List of works - Renzo Luisi

1,3-Dibromo-1,1-difluoro-2-propanone as a Useful Synthon for a Chemoselective Preparation of 4-Bromodifluoromethyl Thiazoles

scientific article published on 05 November 2018

2-Lithio-3,3-dimethyl-2-oxazolinyloxirane: carbanion or azaenolate? Structure, configurational stability, and stereodynamics in solution

scientific article

A Study of Graphene-Based Copper Catalysts: Copper(I) Nanoplatelets for Batch and Continuous-Flow Applications

scientific article published on 13 August 2019

A convenient enantioselective CBS-reduction of arylketones in flow-microreactor systems.

scientific article published on 18 April 2016

A direct and sustainable synthesis of tertiary butyl esters enabled by flow microreactors.

scientific article

A facile and regioselective multicomponent synthesis of chiral aryl-1,2-mercaptoamines in water followed by monoamine oxidase (MAO-N) enzymatic resolution

scientific article published on 04 October 2019

A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles.

scientific article published in June 2017

A stereospecific synthesis of oxazolinyloxiranes

scientific article published on 01 May 2001

Alpha- vs ortho-lithiation of N-alkylarylaziridines: probing the role of the nitrogen inversion process

scientific article

Alpha-substituted alpha-lithiated oxiranes: useful reactive intermediates.

scientific article published on June 2008

An efficient route to tetrahydronaphthols via addition of ortho-lithiated stilbene oxides to alpha,beta-unsaturated fischer carbene Complexes

scientific article published on 01 October 2005

Asymmetric synthesis of cyclopropanes from lithiated aryloxiranes and alpha,beta-unsaturated Fischer carbene complexes

scientific article published in July 2005

Azetidine-Borane Complexes: Synthesis, Reactivity, and Stereoselective Functionalization

scientific article published on 30 July 2018

Aziridinyl anions: generation, reactivity, and use in modern synthetic chemistry.

scientific article published on September 2010

BH3-promoted stereoselective β-lithiation of N-alkyl-2-phenylaziridines

scientific article published on 02 March 2011

Carbolithiation of S-alkenyl-N-aryl thiocarbamates: carbanion arylation in a connective route to tertiary thiols.

scientific article published on 15 April 2013

Continuous Flow Synthesis of Heterocycles: A Recent Update on the Flow Synthesis of Indoles

scientific article published on 16 July 2020

Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis

scientific article

Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents

scientific article published on 4 November 2014

Directed ortho lithiation of N-alkylphenylaziridines

scientific article published on 01 August 2005

Easy access to constrained peptidomimetics and 2,2-disubstituted azetidines by the unexpected reactivity profile of α-lithiated N-Boc-azetidines

scientific article published on 01 November 2015

Enantioselective carbolithiation of S-alkenyl-N-aryl thiocarbamates: kinetic and thermodynamic control

scientific article published on 01 February 2015

Exploiting a "Beast" in Carbenoid Chemistry: Development of a Straightforward Direct Nucleophilic Fluoromethylation Strategy

scientific article

Flow Microreactor Technology for Taming Highly Reactive Chloroiodomethyllithium Carbenoid: Direct and Chemoselective Synthesis of α-Chloroaldehydes

scientific article published on 10 April 2020

Flow Technology for the Genesis and Use of (Highly) Reactive Organometallic Reagents

scientific article published on 06 November 2019

Harnessing the ortho-directing ability of the azetidine ring for the regioselective and exhaustive functionalization of arenes.

scientific article published on 5 August 2014

Highly Chemoselective NH- and O-Transfer to Thiols Using Hypervalent Iodine Reagents: Synthesis of Sulfonimidates and Sulfonamides.

scientific article published on 13 April 2018

Lithiation of N-alkyl-(o-tolyl)aziridine: stereoselective synthesis of isochromans.

scientific article published in August 2009

Metalation of 2-chloromethyl-2-oxazolines: synthesis of 1,2,3-tris(oxazolinyl)cyclopropanes and derivatives

scientific article published in February 2002

Michael addition of chloroalkyloxazolines to electron-poor alkenes: synthesis of heterosubstituted cyclopropanes.

scientific article published in February 2003

Michael addition of ortho-lithiated aryloxiranes to alpha,beta-unsaturated malonates: synthesis of tetrahydroindenofuranones

scientific article published on 19 April 2008

Modular and Chemoselective Strategy for the Direct Access to α-Fluoroepoxides and Aziridines via the Addition of Fluoroiodomethyllithium to Carbonyl-Like Compounds

scientific article published on 02 January 2019

New anti-viral drugs for the treatment of the common cold

scientific article

New arylaziridinyldifluoroborates: useful Suzuki-Miyaura reagents

scientific article published in March 2010

New synthesis of optically active 5-isoxazolidinones and beta-amino acids

scientific article published on 01 December 2003

Nitrogen Stereodynamics and Complexation Phenomena as Key Factors in the Deprotonative Dynamic Resolution of Alkylideneaziridines: A Spectroscopic and Computational Study.

scientific article

Nitrogen dynamics and reactivity of chiral aziridines: generation of configurationally stable aziridinyllithium compounds

scientific article published on 04 April 2011

One-pot preparation of piperazines by regioselective ring-opening of non-activated arylaziridines

scientific article published on 30 January 2012

One-pot regioselective synthesis of nitrophenyloxazolinyl styrene oxides by the Darzens reaction of vicarious nucleophilic substitution-formed carbanions of 2-dichloromethyl-4,4-dimethyloxazoline

scientific article published in July 2004

Oxazolinyloxiranyllithium-mediated stereoselective synthesis of alpha-epoxy-beta-amino acids

scientific article published on 01 July 2003

Oxiranyl anion-mediated synthesis of highly enantiomerically enriched styrene oxide derivatives

scientific article published on 01 July 2002

Pharmaceutical development of novel lactate-based 6-fluoro-l-DOPA formulations.

scientific article published on 4 October 2016

Recent advances in the chemistry of metallated azetidines.

scientific article published on 9 November 2016

Recent advances in the stereoselective synthesis of aziridines.

scientific article published on 13 May 2014

Regio- and Stereoselective Synthesis of Sulfur-Bearing Four-Membered Heterocycles: Direct Access to 2,4-Disubstituted Thietane 1-Oxides

scientific article published on 02 December 2015

Regio- and stereoselective lithiation and electrophilic substitution reactions of N-Alkyl-2,3-diphenylaziridines: solvent effect.

scientific article published on 6 March 2007

Regio- and stereoselective lithiation of 2,3-diphenylaziridines: a multinuclear NMR investigation

scientific article

Regio- and stereoselective lithiation of terminal oxazolinylaziridines: the aziridine N-substituent and the oxazolinyl group effect

scientific article published on 26 July 2007

Regioselective functionalization of 2-arylazetidines: evaluating the ortho-directing ability of the azetidinyl ring and the α-directing ability of the N-substituent

scientific article published on 06 January 2014

Solvent- and temperature-dependent functionalisation of enantioenriched aziridines

scientific article published on 12 November 2010

Stereo- and Enantioselective Addition of Organolithiums to 2-Oxazolinylazetidines as a Synthetic Route to 2-Acylazetidines

scientific article published on 10 September 2019

Stereocontrolled lithiation/trapping of chiral 2-alkylideneaziridines: investigation into the role of the aziridine nitrogen stereodynamics

scientific article published on 01 November 2014

Stereoselective synthesis of novel 4,5-epoxy-1,2-oxazin-6-ones and alpha,beta-epoxy-gamma-amino acids from beta-lithiated oxazolinyloxiranes and nitrones

scientific article published on 01 October 2006

Stereoselective synthesis of novel beta,gamma-epoxyhydroxylamines and 4-hydroxyalkyl-1,2-oxazetidines

scientific article published on 01 August 2006

Stereoselective synthesis of pentacarbonyl(3-oxa-2-bicyclo[3.1.0]hexylidene)- and pentacarbonyl(cyclopropylmethoxymethylene)tungsten compounds on the route to cyclopropane-gamma-lactones and -carboxylates

scientific article published on 01 December 2004

Stereospecific beta-lithiation of oxazolinyloxiranes: synthesis of alpha,beta-epoxy-gamma-butyrolactones

scientific article published on 01 May 2002

Stereospecific synthesis of optically active phenylpropylene oxides

scientific article

Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide.

scientific article published in April 2014

Straightforward chemo- and stereoselective fluorocyclopropanation of allylic alcohols: exploiting the electrophilic nature of the not so elusive fluoroiodomethyllithium

scientific article published on 01 July 2019

Supported Catalysts for Continuous Flow Synthesis

scientific article published on 24 November 2018

Synthesis of 1,2,3,4-tetrahydroisoquinolines by microreactor-mediated thermal isomerization of laterally lithiated arylaziridines

scientific article

Synthesis of 1,3-dihydrobenzo[c]furans from ortho-lithiated aryloxiranes

scientific article published on 01 May 2006

Synthesis of 2,3-dihydro-10bh-oxazolo[2,3-a]isoquinolines from ortho-lithiated phenyloxazolinyloxiranes

scientific article published on 04 July 2007

Synthesis of NH-sulfoximines from sulfides by chemoselective one-pot N- and O-transfers.

scientific article

Synthesis of Sulfinamidines and Sulfinimidate Esters by Transfer of Nitrogen to Sulfenamides

scientific article published on 28 August 2020

Synthesis of Sulfonimidamides from Sulfenamides via an Alkoxy-amino-λ6 -sulfanenitrile Intermediate

scientific article published on 28 August 2019

Synthesis of Sulfoximine Carbamates by Rhodium-Catalyzed Nitrene Transfer of Carbamates to Sulfoxides

scientific article published on 02 June 2015

Synthesis of allylic alcohols from oxazolinyloxiranes

scientific article

Synthesis of enantiomerically enriched oxazolinyl[1,2]oxazetidines

scientific article published on 01 December 2003

Synthesis of functionalized arylaziridines as potential antimicrobial agents.

scientific article published on 4 August 2014

Synthesis of glycosyl sulfoximines by a highly chemo- and stereoselective NH- and O-transfer to thioglycosides

scientific article published on 11 May 2020

Synthesis of optically active arylaziridines by regio- and stereospecific lithiation of N-bus-phenylaziridine

scientific article published on 01 January 2009

Synthetic approach to substituted cyclopropanes based on the coupling reaction of lithiated chloroalkyloxazolines with Fischer carbene complexes

scientific article

The renaissance of strained 1-azabicyclo[1.1.0]butanes as useful reagents for the synthesis of functionalized azetidines

scientific article published on 20 July 2020

Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides

scientific article published on 29 April 2016

List of works by Renzo Luisi

1,3-Dibromo-1,1-difluoro-2-propanone as a Useful Synthon for a Chemoselective Preparation of 4-Bromodifluoromethyl Thiazoles

2-Lithio-3,3-dimethyl-2-oxazolinyloxirane: carbanion or azaenolate? Structure, configurational stability, and stereodynamics in solution

A Study of Graphene-Based Copper Catalysts: Copper(I) Nanoplatelets for Batch and Continuous-Flow Applications

A convenient enantioselective CBS-reduction of arylketones in flow-microreactor systems.

A direct and sustainable synthesis of tertiary butyl esters enabled by flow microreactors.

A facile and regioselective multicomponent synthesis of chiral aryl-1,2-mercaptoamines in water followed by monoamine oxidase (MAO-N) enzymatic resolution

A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles.

A stereospecific synthesis of oxazolinyloxiranes

Alpha- vs ortho-lithiation of N-alkylarylaziridines: probing the role of the nitrogen inversion process

Alpha-substituted alpha-lithiated oxiranes: useful reactive intermediates.

An efficient route to tetrahydronaphthols via addition of ortho-lithiated stilbene oxides to alpha,beta-unsaturated fischer carbene Complexes

Asymmetric synthesis of cyclopropanes from lithiated aryloxiranes and alpha,beta-unsaturated Fischer carbene complexes

Azetidine-Borane Complexes: Synthesis, Reactivity, and Stereoselective Functionalization

Aziridinyl anions: generation, reactivity, and use in modern synthetic chemistry.

BH3-promoted stereoselective β-lithiation of N-alkyl-2-phenylaziridines

Carbolithiation of S-alkenyl-N-aryl thiocarbamates: carbanion arylation in a connective route to tertiary thiols.

Continuous Flow Synthesis of Heterocycles: A Recent Update on the Flow Synthesis of Indoles

Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis

Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents

Directed ortho lithiation of N-alkylphenylaziridines

Easy access to constrained peptidomimetics and 2,2-disubstituted azetidines by the unexpected reactivity profile of α-lithiated N-Boc-azetidines

Enantioselective carbolithiation of S-alkenyl-N-aryl thiocarbamates: kinetic and thermodynamic control

Exploiting a "Beast" in Carbenoid Chemistry: Development of a Straightforward Direct Nucleophilic Fluoromethylation Strategy

Flow Microreactor Technology for Taming Highly Reactive Chloroiodomethyllithium Carbenoid: Direct and Chemoselective Synthesis of α-Chloroaldehydes

Flow Technology for the Genesis and Use of (Highly) Reactive Organometallic Reagents

Harnessing the ortho-directing ability of the azetidine ring for the regioselective and exhaustive functionalization of arenes.

Highly Chemoselective NH- and O-Transfer to Thiols Using Hypervalent Iodine Reagents: Synthesis of Sulfonimidates and Sulfonamides.

Lithiation of N-alkyl-(o-tolyl)aziridine: stereoselective synthesis of isochromans.

Metalation of 2-chloromethyl-2-oxazolines: synthesis of 1,2,3-tris(oxazolinyl)cyclopropanes and derivatives

Michael addition of chloroalkyloxazolines to electron-poor alkenes: synthesis of heterosubstituted cyclopropanes.

Michael addition of ortho-lithiated aryloxiranes to alpha,beta-unsaturated malonates: synthesis of tetrahydroindenofuranones

Modular and Chemoselective Strategy for the Direct Access to α-Fluoroepoxides and Aziridines via the Addition of Fluoroiodomethyllithium to Carbonyl-Like Compounds

New anti-viral drugs for the treatment of the common cold

New arylaziridinyldifluoroborates: useful Suzuki-Miyaura reagents

New synthesis of optically active 5-isoxazolidinones and beta-amino acids

Nitrogen Stereodynamics and Complexation Phenomena as Key Factors in the Deprotonative Dynamic Resolution of Alkylideneaziridines: A Spectroscopic and Computational Study.

Nitrogen dynamics and reactivity of chiral aziridines: generation of configurationally stable aziridinyllithium compounds

One-pot preparation of piperazines by regioselective ring-opening of non-activated arylaziridines

One-pot regioselective synthesis of nitrophenyloxazolinyl styrene oxides by the Darzens reaction of vicarious nucleophilic substitution-formed carbanions of 2-dichloromethyl-4,4-dimethyloxazoline

Oxazolinyloxiranyllithium-mediated stereoselective synthesis of alpha-epoxy-beta-amino acids

Oxiranyl anion-mediated synthesis of highly enantiomerically enriched styrene oxide derivatives

Pharmaceutical development of novel lactate-based 6-fluoro-l-DOPA formulations.

Recent advances in the chemistry of metallated azetidines.

Recent advances in the stereoselective synthesis of aziridines.

Regio- and Stereoselective Synthesis of Sulfur-Bearing Four-Membered Heterocycles: Direct Access to 2,4-Disubstituted Thietane 1-Oxides

Regio- and stereoselective lithiation and electrophilic substitution reactions of N-Alkyl-2,3-diphenylaziridines: solvent effect.

Regio- and stereoselective lithiation of 2,3-diphenylaziridines: a multinuclear NMR investigation

Regio- and stereoselective lithiation of terminal oxazolinylaziridines: the aziridine N-substituent and the oxazolinyl group effect

Regioselective functionalization of 2-arylazetidines: evaluating the ortho-directing ability of the azetidinyl ring and the α-directing ability of the N-substituent

Solvent- and temperature-dependent functionalisation of enantioenriched aziridines

Stereo- and Enantioselective Addition of Organolithiums to 2-Oxazolinylazetidines as a Synthetic Route to 2-Acylazetidines

Stereocontrolled lithiation/trapping of chiral 2-alkylideneaziridines: investigation into the role of the aziridine nitrogen stereodynamics

Stereoselective synthesis of novel 4,5-epoxy-1,2-oxazin-6-ones and alpha,beta-epoxy-gamma-amino acids from beta-lithiated oxazolinyloxiranes and nitrones

Stereoselective synthesis of novel beta,gamma-epoxyhydroxylamines and 4-hydroxyalkyl-1,2-oxazetidines

Stereoselective synthesis of pentacarbonyl(3-oxa-2-bicyclo[3.1.0]hexylidene)- and pentacarbonyl(cyclopropylmethoxymethylene)tungsten compounds on the route to cyclopropane-gamma-lactones and -carboxylates

Stereospecific beta-lithiation of oxazolinyloxiranes: synthesis of alpha,beta-epoxy-gamma-butyrolactones

Stereospecific synthesis of optically active phenylpropylene oxides

Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide.

Straightforward chemo- and stereoselective fluorocyclopropanation of allylic alcohols: exploiting the electrophilic nature of the not so elusive fluoroiodomethyllithium

Supported Catalysts for Continuous Flow Synthesis

Synthesis of 1,2,3,4-tetrahydroisoquinolines by microreactor-mediated thermal isomerization of laterally lithiated arylaziridines

Synthesis of 1,3-dihydrobenzo[c]furans from ortho-lithiated aryloxiranes

Synthesis of 2,3-dihydro-10bh-oxazolo[2,3-a]isoquinolines from ortho-lithiated phenyloxazolinyloxiranes

Synthesis of NH-sulfoximines from sulfides by chemoselective one-pot N- and O-transfers.

Synthesis of Sulfinamidines and Sulfinimidate Esters by Transfer of Nitrogen to Sulfenamides

Synthesis of Sulfonimidamides from Sulfenamides via an Alkoxy-amino-λ6 -sulfanenitrile Intermediate

Synthesis of Sulfoximine Carbamates by Rhodium-Catalyzed Nitrene Transfer of Carbamates to Sulfoxides

Synthesis of allylic alcohols from oxazolinyloxiranes

Synthesis of enantiomerically enriched oxazolinyl[1,2]oxazetidines

Synthesis of functionalized arylaziridines as potential antimicrobial agents.

Synthesis of glycosyl sulfoximines by a highly chemo- and stereoselective NH- and O-transfer to thioglycosides

Synthesis of optically active arylaziridines by regio- and stereospecific lithiation of N-bus-phenylaziridine

Synthetic approach to substituted cyclopropanes based on the coupling reaction of lithiated chloroalkyloxazolines with Fischer carbene complexes

The renaissance of strained 1-azabicyclo[1.1.0]butanes as useful reagents for the synthesis of functionalized azetidines

Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides