List of works - Michelle Peckham

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

scientific article

The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head

scientific article published on 18 July 2005

Physiological properties of the dorsal longitudinal flight muscle and the tergal depressor of the trochanter muscle of Drosophila melanogaster

scientific article published on June 1990

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome

scientific journal article

Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes

scientific article

A FERM domain autoregulates Drosophila myosin 7a activity

scientific article

Dimerization of mammalian kinesin-3 motors results in superprocessive motion

scientific article published on 02 April 2014

The SAH domain extends the functional length of the myosin lever

scientific article published on 15 December 2009

Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse

scientific journal article

Targeted homozygous deletion of M-band titin in cardiomyocytes prevents sarcomere formation

scientific article published on October 2006

Visualizing single molecules inside living cells using total internal reflection fluorescence microscopy.

scientific article

Structural implications of β-cardiac myosin heavy chain mutations in human disease

scientific article

Alteration in crossbridge kinetics caused by mutations in actin

scientific article published in November 1990

The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblasts

scientific article published on 18 January 2004

Alignment of myoblasts on ultrafine gratings inhibits fusion in vitro.

scientific article published on July 2002

Modulation of cell spreading and cell-substrate adhesion dynamics by dystroglycan.

scientific article

LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells

scientific article published on January 2006

Preferential Adhesion to and Survival on Patterned Laminin Organizes Myogenesisin Vitro

scientific article published on 01 February 1997

Affimer proteins are versatile and renewable affinity reagents

scientific article

A targeted deletion of the C-terminal end of titin, including the titin kinase domain, impairs myofibrillogenesis

scientific article published in December 2003

Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells

scientific article published on 6 December 2015

Engineering a multi-nucleated myotube, the role of the actin cytoskeleton

scientific article published on September 2008

Specific changes to the mechanism of cell locomotion induced by overexpression of beta-actin.

scientific article published in April 2001

The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis

scientific article

Evidence for differential post-translational modifications of slow myosin heavy chain during murine skeletal muscle development

scientific article published in February 2000

Constitutive and variable regions of Z-disk titin/connectin in myofibril formation: a dominant-negative screen

scientific article published in February 1997

Construction of an instant structured illumination microscope

scientific article published on 22 July 2015

Stable single α-helices are constant force springs in proteins

scientific article

Myogenic cells express multiple myosin isoforms

scientific article published on October 1, 1997

Microtubule assembly in cultured myoblasts and myotubes following nocodazole induced microtubule depolymerisation

scientific article published in January 2003

Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells

scientific article

Actin filament organization in aligned prefusion myoblasts

scientific article

Labile heat and changes in rate of relaxation of frog muscles.

scientific article published on May 1986

Intranuclear rod myopathy: molecular pathogenesis and mechanisms of weakness

scientific article published on December 2007

Coiled coils and SAH domains in cytoskeletal molecular motors

scientific article published on October 1, 2011

Cardiomyopathy mutations in the tail of β-cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes

scientific article published on 18 September 2013

Microtubule proliferation in right ventricular myocytes of rats with monocrotaline-induced pulmonary hypertension

scientific article published on 21 December 2012

Site-Specific Labeling of Affimers for DNA-PAINT Microscopy

scientific article published on 15 July 2018

Myosin crossbridge orientation in demembranated muscle fibres studied by birefringence and X-ray diffraction measurements

scientific article published on 01 November 1989

How myosin organization of the actin cytoskeleton contributes to the cancer phenotype

scientific article published on August 2016

Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation

scientific article published on 10 June 2016

Apolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanisms

scientific article

The sarcomere length dependence of the rate of heat production during isometric tetanic contraction of frog muscles

article

Heterologous expression of wild-type and mutant beta-cardiac myosin changes the contractile kinetics of cultured mouse myotubes

scientific article published on 7 February 2003

Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability

scientific article published on 13 March 2017

Human congenital myopathy actin mutants cause myopathy and alter Z-disc structure in Drosophila flight muscle

scientific article published on 5 January 2013

A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development

scientific article

Histone deacetylase 3 indirectly modulates tubulin acetylation

scientific article published on 8 October 2015

A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip

scientific article

Alternative reagents to antibodies in imaging applications

scientific article published on 27 July 2017

List of works by Michelle Peckham

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head

Physiological properties of the dorsal longitudinal flight muscle and the tergal depressor of the trochanter muscle of Drosophila melanogaster

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome

Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes

A FERM domain autoregulates Drosophila myosin 7a activity

Dimerization of mammalian kinesin-3 motors results in superprocessive motion

The SAH domain extends the functional length of the myosin lever

Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse

Targeted homozygous deletion of M-band titin in cardiomyocytes prevents sarcomere formation

Visualizing single molecules inside living cells using total internal reflection fluorescence microscopy.

Structural implications of β-cardiac myosin heavy chain mutations in human disease

Alteration in crossbridge kinetics caused by mutations in actin

The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblasts

Alignment of myoblasts on ultrafine gratings inhibits fusion in vitro.

Modulation of cell spreading and cell-substrate adhesion dynamics by dystroglycan.

LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells

Preferential Adhesion to and Survival on Patterned Laminin Organizes Myogenesisin Vitro

Affimer proteins are versatile and renewable affinity reagents

A targeted deletion of the C-terminal end of titin, including the titin kinase domain, impairs myofibrillogenesis

Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells

Engineering a multi-nucleated myotube, the role of the actin cytoskeleton

Specific changes to the mechanism of cell locomotion induced by overexpression of beta-actin.

The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis

Evidence for differential post-translational modifications of slow myosin heavy chain during murine skeletal muscle development

Constitutive and variable regions of Z-disk titin/connectin in myofibril formation: a dominant-negative screen

Construction of an instant structured illumination microscope

Stable single α-helices are constant force springs in proteins

Myogenic cells express multiple myosin isoforms

Microtubule assembly in cultured myoblasts and myotubes following nocodazole induced microtubule depolymerisation

Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells

Actin filament organization in aligned prefusion myoblasts

Labile heat and changes in rate of relaxation of frog muscles.

Intranuclear rod myopathy: molecular pathogenesis and mechanisms of weakness

Coiled coils and SAH domains in cytoskeletal molecular motors

Cardiomyopathy mutations in the tail of β-cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes

Microtubule proliferation in right ventricular myocytes of rats with monocrotaline-induced pulmonary hypertension

Site-Specific Labeling of Affimers for DNA-PAINT Microscopy

Myosin crossbridge orientation in demembranated muscle fibres studied by birefringence and X-ray diffraction measurements

How myosin organization of the actin cytoskeleton contributes to the cancer phenotype

Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation

Apolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanisms

The sarcomere length dependence of the rate of heat production during isometric tetanic contraction of frog muscles

Heterologous expression of wild-type and mutant beta-cardiac myosin changes the contractile kinetics of cultured mouse myotubes

Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability

Human congenital myopathy actin mutants cause myopathy and alter Z-disc structure in Drosophila flight muscle

A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development

Histone deacetylase 3 indirectly modulates tubulin acetylation

A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip

Alternative reagents to antibodies in imaging applications