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List of works by Luís Filipe C Castro

"Out of the Can": A Draft Genome Assembly, Liver Transcriptome, and Nutrigenomics of the European Sardine, Sardina pilchardus

scientific article published on 09 October 2018

A Gbx homeobox gene in amphioxus: insights into ancestry of the ANTP class and evolution of the midbrain/hindbrain boundary

scientific article

A complete enzymatic capacity for long-chain polyunsaturated fatty acid biosynthesis is present in the Amazonian teleost tambaqui, Colossoma macropomum

scientific article published on 02 October 2018

A cytosolic carbonic anhydrase molecular switch occurs in the gills of metamorphic sea lamprey

scientific article published on 05 October 2016

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages

scientific article published on 30 April 2013

A draft genome sequence of the elusive giant squid, Architeuthis dux

scientific article published on 01 January 2020

A mollusk VDR/PXR/CAR-like (NR1J) nuclear receptor provides insight into ancient detoxification mechanisms

scientific article published on 17 February 2016

A mollusk retinoic acid receptor (RAR) ortholog sheds light on the evolution of ligand binding.

scientific article

A novel Acetyl-CoA synthetase short-chain subfamily member 1 (Acss1) gene indicates a dynamic history of paralogue retention and loss in vertebrates

article

A real-time PCR assay for differential expression of vitellogenin I and II genes in the liver of the sentinel fish species Lipophrys pholis.

scientific article published on 8 October 2013

A resource for sustainable management: De novo assembly and annotation of the liver transcriptome of the Atlantic chub mackerel, Scomber colias.

scientific article published on 13 March 2018

ABC transporters, CYP1A and GSTα gene transcription patterns in developing stages of the Nile tilapia (Oreochromis niloticus) ⬇️

scientific article published on July 7, 2012

Acid phosphatase polymorphism in European shad (Fish: Clupeids)

scientific article published on 01 August 1999

Acyl-coenzyme A oxidases 1 and 3 in brown trout (Salmo trutta f. fario): Can peroxisomal fatty acid β-oxidation be regulated by estrogen signaling?

scientific article published on 27 October 2015

Adaptive evolution of the Retinoid X receptor in vertebrates

scientific article published on 14 December 2011

An Orthologue of the Retinoic Acid Receptor (RAR) Is Present in the Ecdysozoa Phylum Priapulida

scientific article published on 29 November 2019

An antecedent of the MHC-linked genomic region in amphioxus

scientific article published on 29 January 2004

An important resource for understanding bio-adhesion mechanisms: Cement gland transcriptomes of two goose barnacles, Pollicipes pollicipes and Lepas anatifera (Cirripedia, Thoracica)

Anti-androgenic effects of sewage treatment plant effluents in the prosobranch gastropod Nucella lapillus

scientific article

Basal Gnathostomes provide unique insights into the evolution of vitamin B12 binders.

scientific article published on 31 December 2014

Cartilaginous fishes offer unique insights into the evolution of the nuclear receptor gene repertoire in gnathostomes

scientific article published on 08 June 2020

Cetacea are natural knockouts for IL20

scientific article published on 12 July 2018

Chromosomal mapping of ANTP class homeobox genes in amphioxus: piecing together ancestral genomes.

scientific article

Chronic effects of clofibric acid in zebrafish (Danio rerio): a multigenerational study

scientific article published on 16 January 2015

Cloning and expression analysis of the 17β hydroxysteroid dehydrogenase type 12 (HSD17B12) in the neogastropod Nucella lapillus.

scientific article published on 13 October 2012

Comparative Analysis of the Adhesive Proteins of the Adult Stalked Goose Barnacle Pollicipes pollicipes (Cirripedia: Pedunculata)

article published in 2018

Complete Inactivation of Sebum-Producing Genes Parallels the Loss of Sebaceous Glands in Cetacea

article

Convergent inactivation of the skin-specific C-C motif chemokine ligand 27 in mammalian evolution

scientific article published on 02 May 2019

Cross-interference of two model peroxisome proliferators in peroxisomal and estrogenic pathways in brown trout hepatocytes.

scientific article published on 6 April 2017

De novo assembly of the kidney and spleen transcriptomes of the cosmopolitan blue shark, Prionace glauca

scientific article published on 06 December 2017

Dietary Creatine Supplementation in Gilthead Seabream () Increases Dorsal Muscle Area and the Expression of and Genes

article

Dietary Oil Source and Selenium Supplementation Modulate Fads2 and Elovl5 Transcriptional Levels in Liver and Brain of Meagre (Argyrosomus regius).

scientific article

Diets supplemented with Saccharina latissima influence the expression of genes related to lipid metabolism and oxidative stress modulating rainbow trout (Oncorhynchus mykiss) fillet composition

scientific article published on 16 April 2020

Differences in retinoid levels and metabolism among gastropod lineages: imposex-susceptible gastropods lack the ability to store retinoids in the form of retinyl esters

scientific article published on 11 August 2013

Dispersal of NK homeobox gene clusters in amphioxus and humans

scholarly article

Disruption of zebrafish (Danio rerio) embryonic development after full life-cycle parental exposure to low levels of ethinylestradiol.

scientific article published on 5 August 2009

Diversity and history of the long-chain acyl-CoA synthetase (Acsl) gene family in vertebrates

scientific article

Dynamics of PPARs, fatty acid metabolism genes and lipid classes in eggs and early larvae of a teleost.

scientific article published on February 2013

Ecotoxicology of deep-sea environments: Functional and biochemical effects of suspended sediments in the model species Mytilus galloprovincialis under hyperbaric conditions

scientific article published on 14 March 2019

Effects of Tributyltin and Other Retinoid Receptor Agonists in Reproductive-Related Endpoints in the Zebrafish (Danio rerio).

scientific article published on January 2015

Effects of the PPARα agonist WY-14,643 on plasma lipids, enzymatic activities and mRNA expression of lipid metabolism genes in a marine flatfish, Scophthalmus maximus.

scientific article

Estrogenic and anti-estrogenic influences in cultured brown trout hepatocytes: Focus on the expression of some estrogen and peroxisomal related genes and linked phenotypic anchors.

scientific article published on 24 October 2015

Estrogenic chemical effects are independent from the degree of sex role reversal in pipefish

scientific article published on 28 October 2013

Evolution and Functional Characteristics of the Novel elovl8 That Play Pivotal Roles in Fatty Acid Biosynthesis

scientific article published in 2021

Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages. ⬇️

scientific article published on 10 May 2019

Evolutionary functional elaboration of the Elovl2/5 gene family in chordates

scientific article published on 09 February 2016

Expansion, retention and loss in the Acyl-CoA synthetase "Bubblegum" (Acsbg) gene family in vertebrate history.

scientific article published on 22 April 2018

Expression of intercellular lipid transport and cholesterol metabolism genes in eggs and early larvae stages of turbot, Scophthalmus maximus, a marine aquaculture species

article

Fluorescentin situHybridisation to Amphioxus Chromosomes

article

From the Amazon: A comprehensive liver transcriptome dataset of the teleost fish tambaqui, Colossoma macropomum

scientific article published on 07 March 2019

Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates

scientific article

Gene expression analysis of ABC efflux transporters, CYP1A and GSTα in Nile tilapia after exposure to benzo(a)pyrene.

scientific article published on 23 December 2011

Genes for de novo biosynthesis of omega-3 polyunsaturated fatty acids are widespread in animals.

scientific article

Genome specific PPARαB duplicates in salmonids and insights into estrogenic regulation in brown trout

scientific article published on 14 April 2017

Genomic approach in evaluating the role of androgens on the growth of Atlantic cod (Gadus morhua) previtellogenic oocytes.

scientific article

He cycling gonad: Retinoic-acid synthesis and degradation patterns during adult zebrafish Danio rerio oogenesis

scientific article published on 21 February 2018

Hidden in the blow - a matrix to characterise cetaceans’ respiratory microbiome: short-finned pilot whale as case study

scientific article published in 2024

Imposex development in Hexaplex trunculus (Gastropoda: Caenogastropoda) involves changes in the transcription levels of the retinoid X receptor (RXR).

scientific article published on 12 July 2013

Imposex induction is mediated through the Retinoid X Receptor signalling pathway in the neogastropod Nucella lapillus

scientific article published on 11 August 2007

In vitro exposure of Nile tilapia (Oreochromis niloticus) testis to estrogenic endocrine disrupting chemicals: mRNA expression of genes encoding steroidogenic enzymes

scientific article published on July 2011

Is there a compromise between nutrient uptake and gas exchange in the gut of Misgurnus anguillicaudatus, an intestinal air-breathing fish?

scientific article published on 4 September 2007

LXRα and LXRβ Nuclear Receptors Evolved in the Common Ancestor of Gnathostomes

scientific article published on 04 January 2017

Linking chemical exposure to lipid homeostasis: A municipal waste water treatment plant influent is obesogenic for zebrafish larvae

scientific article published on 06 July 2019

Liver transcriptome resources of four commercially exploited teleost species

scientific article published on 07 July 2020

Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire

scientific article

Losing Genes: The Evolutionary Remodeling of Cetacea Skin ⬇️

scholarly article

Molecular and functional characterization of a fads2 orthologue in the Amazonian teleost, Arapaima gigas.

scientific article published on 29 September 2016

Molecular ontogeny of the stomach in the catshark Scyliorhinus canicula

scientific article published in Scientific Reports

Multi-matrix quantification and risk assessment of pesticides in the longest river of the Iberian peninsula

scientific article published on 5 August 2016

Natural history of SLC11 genes in vertebrates: tales from the fish world

scientific article

New insights into the mechanism of imposex induction in the dogwhelk Nucella lapillus

scientific article published in May 2005

No more than 14: the end of the amphioxus Hox cluster

scientific article

Normalization strategies for gene expression studies by real-time PCR in a marine fish species, Scophthalmus maximus.

scientific article published on 19 March 2013

Of Retinoids and Organotins: The Evolution of the Retinoid X Receptor in Metazoa

scientific article published on 11 April 2020

Organotin levels in seafood from Portuguese markets and the risk for consumers

scientific article published on 23 February 2009

Peroxisome proliferator-activated receptor gamma (PPARγ) in brown trout: Interference of estrogenic and androgenic inputs in primary hepatocytes.

scientific article published on 9 August 2016

Pex11α in brown trout (Salmo trutta f. fario): Expression dynamics during the reproductive cycle reveals sex-specific seasonal patterns

scientific article

PseudoChecker: an integrated online platform for gene inactivation inference

scientific article published on 25 May 2020

Rapid-behaviour responses as a reliable indicator of estrogenic chemical toxicity in zebrafish juveniles.

scientific article published on 8 September 2011

Recurrent gene loss correlates with the evolution of stomach phenotypes in gnathostome history.

scientific article

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain

scientific article

Retention of fatty acyl desaturase 1 (fads1) in Elopomorpha and Cyclostomata provides novel insights into the evolution of long-chain polyunsaturated fatty acid biosynthesis in vertebrates

scientific article published on 19 October 2018

Retinoid level dynamics during gonad recycling in the limpet Patella vulgata

scientific article published on 24 October 2015

Retinoid metabolism in invertebrates: when evolution meets endocrine disruption

scientific article

Retinol metabolism in the mollusk Osilinus lineatus indicates an ancient origin for retinyl ester storage capacity

scientific article

Seasonal and gender variation of peroxisome proliferator activated receptors expression in brown trout liver.

scientific article published on 3 December 2008

Sex-steroids and hypolipidemic chemicals impacts on brown trout lipid and peroxisome signaling — Molecular, biochemical and morphological insights

scientific article published on 07 June 2018

Silencing of PPARαBb mRNA in brown trout primary hepatocytes: effects on molecular and morphological targets under the influence of an estrogen and a PPARα agonist

scientific article published on 07 December 2018

Statins: An undesirable class of aquatic contaminants?

scientific article

Testosterone-induced modulation of peroxisomal morphology and peroxisome-related gene expression in brown trout (Salmo trutta f. fario) primary hepatocytes.

scientific article published on 28 September 2017

The 17beta-hydroxysteroid dehydrogenase 4: Gender-specific and seasonal gene expression in the liver of brown trout (Salmo trutta f. fario).

scientific article published on 5 March 2009

The Crown Pearl V2: an improved genome assembly of the European freshwater pearl mussel Margaritifera margaritifera (Linnaeus, 1758)

scientific article published in 2023

The Echinodermata PPAR: Functional characterization and exploitation by the model lipid homeostasis regulator tributyltin

scientific article published on 01 April 2020

The Gastric Phenotype in the Cypriniform Loaches: A Case of Reinvention?

scientific article

The Mammalian "Obesogen" Tributyltin Targets Hepatic Triglyceride Accumulation and the Transcriptional Regulation of Lipid Metabolism in the Liver and Brain of Zebrafish

scientific article

The Origin and Diversity of Cpt1 Genes in Vertebrate Species

scientific article published on 30 September 2015

The Singularity of Cetacea Behavior Parallels the Complete Inactivation of Melatonin Gene Modules

article

The dopamine receptor D5 gene shows signs of independent erosion in toothed and baleen whales

scientific article published on 11 October 2019

The estrogen receptor of the gastropod Nucella lapillus: modulation following exposure to an estrogenic effluent?

scientific article published on 22 July 2007

The evolution of S100A7: an unusual gene expansion in Myotis bats

article

The evolution of pepsinogen C genes in vertebrates: duplication, loss and functional diversification

scientific article (publication date: 2012)

The evolutionary exploitation of vertebrate peroxisome proliferator-activated receptor γ by organotins

scientific article published on 19 November 2018

The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates

scientific article (publication date: 19 May 2011)

The evolutionary portrait of metazoan NAD salvage

scientific article

The evolutionary road to invertebrate thyroid hormone signaling: Perspectives for endocrine disruption processes

scientific article published on 25 May 2019

The fatty acid elongation genes elovl4a and elovl4b are present and functional in the genome of tambaqui (Colossoma macropomum)

scientific article published on 20 April 2020

The genomic environment around the Aromatase gene: evolutionary insights

scientific article

The last frontier : Coupling technological developments with scientific challenges to improve hazard assessment of deep-sea mining

scientific article published on 20 February 2018

The retinoic acid receptor (RAR) in molluscs: Function, evolution and endocrine disruption insights

scientific article published on 07 January 2019

Tissue expression of PPAR-alpha isoforms in Scophthalmus maximus and transcriptional response of target genes in the heart after exposure to WY-14643 ⬇️

scientific article published on December 25, 2012

Tissue-specific distribution patterns of retinoids and didehydroretinoids in rainbow trout Oncorhynchus mykiss.

scientific article

To bind or not to bind: the taxonomic scope of nuclear receptor mediated endocrine disruption in invertebrate phyla

scientific article published on 8 May 2014

Transgenerational inheritance of chemical-induced signature: A case study with simvastatin

scientific article published on 26 August 2020

Tributyltin (TBT) effects on Hexaplex trunculus and Bolinus brandaris (Gastropoda: Muricidae): Imposex induction and sex hormone levels insights

article published in 2012

Tributyltin Affects Retinoid X Receptor-Mediated Lipid Metabolism in the Marine Rotifer Brachionus koreanus

scientific article published on 19 June 2019

Tributyltin-induced imposex in marine gastropods involves tissue-specific modulation of the retinoid X receptor

scientific article published on 8 October 2010

Two alternative pathways for docosahexaenoic acid (DHA, 22:6n-3) biosynthesis are widespread among teleost fish

scientific article

Unusual loss of chymosin in mammalian lineages parallels neo-natal immune transfer strategies

scientific article published on 26 August 2017

Vitellogenin gene expression in the intertidal blenny Lipophrys pholis: a new sentinel species for estrogenic chemical pollution monitoring in the European Atlantic coast?

scientific article

Zebrafish (Danio rerio) life-cycle exposure to chronic low doses of ethinylestradiol modulates p53 gene transcription within the gonads, but not NER pathways.

scientific article published on 28 April 2012

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