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List of works by Michael D Crabtree

123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo.

scientific article published on 15 January 2015

Author Correction: Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations.

scientific article published on 9 March 2018

Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes.

scientific article published on 25 April 2018

Conserved Helix-Flanking Prolines Modulate Intrinsically Disordered Protein:Target Affinity by Altering the Lifetime of the Bound Complex

scientific article

Folding and binding pathways of BH3-only proteins are encoded within their intrinsically disordered sequence, not templated by partner proteins.

scientific article published in May 2018

GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins.

scientific article published on 8 August 2016

In vitro pharmacological characterization and in vivo validation of LSN3172176 a novel M1 selective muscarinic receptor agonist tracer molecule for positron emission tomography (PET).

scientific article published on 11 April 2018

Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies

scientific article

Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations

scientific article

Thermodynamic mapping of effector protein interfaces with RalA and RalB.

scientific article published on 5 February 2015