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List of works by Michael Stürzl

"Run-off" synthesis and application of defined single-stranded DNA hybridization probes

scientific article published on 01 February 1990

'Run-off' polymerization with digoxigenin labelled nucleotides creates highly sensitive and strand specific DNA hybridization probes: synthesis and application

scientific article published on 01 April 1992

A novel chip-based parallel transfection assay to evaluate paracrine cell interactions

scientific article published on 22 February 2012

A possible role for interferon-alpha and activated natural killer cells in remission of AIDS-related Kaposi's sarcoma: in vitro studies

scientific article

A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.

scientific article published on 19 August 2016

A systems biology approach to identify the combination effects of human herpesvirus 8 genes on NF-kappaB activation

scientific article

Absolute quantification of DcR3 and GDF15 from human serum by LC-ESI MS.

scientific article published on 30 March 2015

Activation of NF-κB by the Kaposi's sarcoma-associated herpesvirus K15 protein involves recruitment of the NF-κB-inducing kinase, IκB kinases, and phosphorylation of p65.

scientific article published on 3 September 2014

Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy

scientific article published in November 2008

Autonomously vascularized cellular constructs in tissue engineering: opening a new perspective for biomedical science

scientific article published on January 2007

Axial prevascularization of porous matrices using an arteriovenous loop promotes survival and differentiation of transplanted autologous osteoblasts

scientific article published on 01 July 2007

Azidothymidine Sensitizes Primary Effusion Lymphoma Cells to Kaposi Sarcoma-Associated Herpesvirus-Specific CD4+ T Cell Control and Inhibits vIRF3 Function

scientific article

Big but weak: how many pathogenic genes does human herpesvirus-8 need to cause Kaposi's sarcoma? (Review)

scientific article published on 01 February 1999

CD40 antigen is expressed by endothelial cells and tumor cells in Kaposi's sarcoma

scientific article published on May 1996

Cell death inhibition by KSHV.

scientific article published in October 2015

Cellular and molecular features of HIV-associated Kaposi's sarcoma

scientific article published on 01 September 1992

Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity

scientific article published on 12 November 2018

Chronic intestinal inflammation in mice expressing viral Flip in epithelial cells

scientific article published on 13 August 2018

Clearance of Human Herpesvirus 8 from Blood and Regression of Leukopenia‐Associated Aggressive Classic Kaposi’s Sarcoma during Interferon‐α Therapy: A Case Report

scientific article published on 12 October 2001

Cocultivation of Mesenchymal Stem Cells and Endothelial Progenitor Cells Reveals Antiapoptotic and Proangiogenic Effects.

scientific article

Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations

scientific article published on 30 August 2014

Consensus-interferon and platelet-derived growth factor adversely regulate proliferation and migration of Kaposi's sarcoma cells by control of c-myc expression

scientific article published on December 1996

Correction: KETOS: Clinical decision support and machine learning as a service - A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services

scientific article published on 13 November 2019

Cytochemical and molecular properties of simian virus 40 transformed Kaposi's sarcoma-derived cells: evidence for the secretion of a member of the fibroblast growth factor family

scientific article published on December 1989

Cytokine profile of HIV-positive Kaposi's sarcoma derived cells in vitro

scientific article published on 01 March 1999

Cytokine-mediated growth promotion of Kaposi's sarcoma and primary effusion lymphoma.

scientific article

Cytotoxic effect of Efavirenz in BxPC-3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation.

scientific article published on 5 December 2017

DNA stool test for colorectal cancer: hypermethylation of the secreted frizzled-related protein-1 gene

scientific article published in October 2007

Deletion of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells

scientific article published on 27 July 2011

EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX.

scientific article published on 21 December 2004

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

scientific article

Endothelial cells of human colorectal cancer and healthy colon reveal phenotypic differences in culture

scientific article

Engineering of vascularized transplantable bone tissues: induction of axial vascularization in an osteoconductive matrix using an arteriovenous loop

scientific article published in July 2006

Expression and localization of axin 2 in colorectal carcinoma and its clinical implication.

scientific article published on 24 May 2013

Expression of HHV-8 latency-associated T0.7 RNA in spindle cells and endothelial cells of AIDS-associated, classical and African Kaposi's sarcoma

scientific article published on July 1997

Expression of Human Herpesvirus 8-Encoded Cyclin D in Kaposi's Sarcoma Spindle Cells

scientific article published on December 17, 1997

Expression of K13/v-FLIP gene of human herpesvirus 8 and apoptosis in Kaposi's sarcoma spindle cells.

scientific article published on October 1999

Expression of adhesion molecules, platelet-activating factor, and chemokines by Kaposi's sarcoma cells

scientific article published on 01 November 1994

Expression of calcitonin receptor-like receptor in human vascular tumours

scientific article published on October 2006

Expression of human herpesvirus-8 (HHV-8) encoded pathogenic genes in Kaposi's Sarcoma (KS) primary lesions

article

Expression of platelet-derived growth factor and its receptor in AIDS-related Kaposi sarcoma in vivo suggests paracrine and autocrine mechanisms of tumor maintenance

scientific article published on August 1, 1992

Expression of the human herpesvirus 8-encoded viral macrophage inflammatory protein-1 gene in Kaposi's sarcoma lesions

scientific article published in June 1998

Expression of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells.

scientific article

Fibrin gel-immobilized VEGF and bFGF efficiently stimulate angiogenesis in the AV loop model

scientific article published on September 2007

GBP-1 acts as a tumor suppressor in colorectal cancer cells.

scientific article

Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor.

scientific article published on 4 November 2013

Gene expression analysis of ischaemia and reperfusion in human microsurgical free muscle tissue transfer.

scientific article published on April 2011

Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton

scientific article

Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin alpha4 expression.

scientific article published on 12 August 2008

Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct

scientific article published on December 6, 2012

Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases

scientific article

HHV-8 and multistep tumorigenesis

scientific article published on 01 August 1999

HIV-1 Tat increases the adhesion of monocytes and T-cells to the endothelium in vitro and in vivo: implications for AIDS-associated vasculopathy

scientific article published in September 2004

Hepatoma-derived integrated HBV DNA causes multi-stage transformation in vitro

scientific article published on 01 April 1996

High throughput screening of gene functions in mammalian cells using reversely transfected cell arrays: review and protocol.

scientific article published on February 2008

Human guanylate binding protein-1 (hGBP-1) characterizes and establishes a non-angiogenic endothelial cell activation phenotype in inflammatory diseases

scientific article

Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis

scientific article

Human herpesvirus-8 (HHV-8) gene expression in Kaposi's sarcoma (KS) primary lesions: an in situ hybridization study

scientific article published in April 1999

Human herpesvirus-8 and Kaposi's sarcoma: relationship with the multistep concept of tumorigenesis.

scientific article

Hypoxia generates a more invasive phenotype of tumour cells: an in vivo experimental setup based on the chorioallantoic membrane.

scientific article

IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: implications for AIDS-Kaposi's sarcoma pathogenesis

scientific article published on 01 January 1999

IFN-γ and TNF-α-induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling

scientific article

IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin-directed vascular barrier disruption

scientific article published on 01 November 2019

IFN-γ-driven intratumoral microenvironment exhibits superior prognostic effect compared with an IFN-α-driven microenvironment in patients with colon carcinoma

scientific article published on 8 October 2013

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD

scientific article published on 25 September 2018

IRAK-M Expression in Tumor Cells Supports Colorectal Cancer Progression through Reduction of Antimicrobial Defense and Stabilization of STAT3.

scientific article

IT infrastructure components to support clinical care and translational research projects in a comprehensive cancer center.

scientific article published on January 2011

Identification of Predictive Markers for Response to Neoadjuvant Chemoradiation in Rectal Carcinomas by Proteomic Isotope Coded Protein Label (ICPL) Analysis.

scientific article published on 4 February 2016

Identification of interleukin-1 and platelet-derived growth factor-B as major mitogens for the spindle cells of Kaposi's sarcoma: a combined in vitro and in vivo analysis

scientific article published on 01 May 1995

Increased expression of guanylate binding protein-1 in lesional skin of patients with cutaneous lupus erythematosus

scientific article published on 02 December 2010

Induction of apoptosis in Kaposi's sarcoma spindle cell cultures by the subunits of human chorionic gonadotropin

article

Induction of apoptosis in circulating angiogenic cells by microparticles

scientific article published on 01 July 2011

Infection with human immunodeficiency virus-1 increases expression of vascular endothelial cell growth factor in T cells: implications for acquired immunodeficiency syndrome-associated vasculopathy.

scientific article published on June 1999

Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin

scientific article (publication date: 15 August 1999)

Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein

scientific article

Interesting image. Tc-99m sestamibi SPECT/CT as a new tool for monitoring perfusion and viability of buried perforator based free flaps in breast reconstruction after breast cancer

scientific article published in January 2010

Interferon Gamma Counteracts the Angiogenic Switch and Induces Vascular Permeability in Dextran Sulfate Sodium Colitis in Mice.

scientific article published on 9 July 2015

Interferon-alpha counteracts the angiogenic switch and reduces tumor cell proliferation in a spontaneous model of prostatic cancer.

scientific article published on 23 February 2009

Interferon-α prevents apoptosis of endothelial cells after short-term exposure but induces replicative senescence after continuous stimulation

Interplay of GTPases and Cytoskeleton in Cellular Barrier Defects during Gut Inflammation.

scientific article published on 5 October 2017

Intracellular localization map of human herpesvirus 8 proteins

scientific article

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner

scientific article

Inverse relation of Fas-ligand and tumor-infiltrating lymphocytes in angiosarcoma: indications of apoptotic tumor counterattack.

scientific article published on September 2001

Isolation of Human Endothelial Cells from Normal Colon and Colorectal Carcinoma - An Improved Protocol

scientific article published on 04 April 2018

Isolation of endothelial cells from human tumors

scientific article published on January 2011

KETOS: Clinical decision support and machine learning as a service - A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services

scientific article published on 03 October 2019

Kaposi sarcoma-associated herpesvirus/human herpesvirus 8, cytokines, growth factors and HIV in pathogenesis of Kaposi's sarcoma

scientific article published on 01 April 1998

Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity.

scientific article published on 16 January 2014

Kaposi's sarcoma-associated herpesvirus gH/gL: glycoprotein export and interaction with cellular receptors.

scientific article published on 22 October 2008

Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line

scientific article

Kaposi's sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents

scientific article published on 01 March 1998

Kaposi's sarcoma: a review of gene expression and ultrastructure of KS spindle cells in vivo

scientific article published on October 1, 1992

Liposomal doxorubicin in the treatment of AIDS-associated Kaposi's sarcoma: clinical, histological and cell biological evaluation

scientific article published on 01 May 1994

Malignant progression of invasive tumour cells seen in hypoxia present an accumulation of beta-catenin in the nucleus at the tumour front.

scientific article

Maternal HIV type 1 infection suppresses MMP-1 expression in endothelial cells of uninfected newborns: nonviral vertical transmission of HIV type 1-related effects

scientific article published in November 2005

Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma.

scientific article published on 10 October 2016

Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.

scientific article published on 30 March 2018

Mechanism of GTPase-activity-induced self-assembly of human guanylate binding protein 1.

scientific article published on 5 May 2010

Mechanism of paclitaxel activity in Kaposi's sarcoma.

scientific article

MiRNA-21 Expression Decreases from Primary Tumors to Liver Metastases in Colorectal Carcinoma

scientific article published on 4 February 2016

Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure

scientific article published on 21 November 2019

Molecular characterization of peripheral arterial disease in proximal extremity arteries.

scientific article

Molecular mechanisms of lymphatic metastasis in solid tumors of the gastrointestinal tract

scientific article

Molecular signature for lymphatic metastasis in colorectal carcinomas

scientific article

Molecular staging of lymph node-negative colon carcinomas by one-step nucleic acid amplification (OSNA) results in upstaging of a quarter of patients in a prospective, European, multicentre study

scientific article

Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8

scientific article published on October 1, 1997

Morphologic HIV demonstration in formalin embedded material--techniques, problems, results

scientific article published in January 1991

Multiple Interferon Regulatory Factor and NF-κB Sites Cooperate in Mediating Cell-Type- and Maturation-Specific Activation of the Human CD83 Promoter in Dendritic Cells

scientific article published on January 22, 2013

Nitric oxide synthases in Kaposi's sarcoma are expressed predominantly by vessels and tissue macrophages

scientific article published on 01 August 1998

Noninvasive Bioluminescence Imaging of AKT Kinase Activity in Subcutaneous and Orthotopic NSCLC Xenografts: Correlation of AKT Activity with Tumor Growth Kinetics

scientific article published on 09 March 2017

Notch3 signalling promotes tumour growth in colorectal cancer.

scientific article published on 19 May 2011

Nuclear factor-kappaB motif and interferon-alpha-stimulated response element co-operate in the activation of guanylate-binding protein-1 expression by inflammatory cytokines in endothelial cells

scientific article

Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1.

scientific article

O-GlcNAc transferase inhibits KSHV propagation and modifies replication relevant viral proteins as detected by systematic O-GlcNAcylation analysis

scientific article published on 11 April 2013

O-linked N-acetylglucosaminylation of Sp1 inhibits the human immunodeficiency virus type 1 promoter

scientific article

Oncogenesis in HIV-infection

article

One step nucleic acid amplification (OSNA) - a new method for lymph node staging in colorectal carcinomas

scientific article

PCR-synthesized single-stranded DNA: a useful tool for 'hyb' and 'HAP' standardization for construction of subtraction libraries

scientific article published on April 1, 1990

PU.1 controls fibroblast polarization and tissue fibrosis

scientific article published on 30 January 2019

Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases

scientific article

Permeability analyses and three dimensional imaging of interferon gamma-induced barrier disintegration in intestinal organoids

scientific article published on 07 February 2019

Predictive value of PD-L1 based on mRNA level in the treatment of stage IV melanoma with ipilimumab.

scientific article published on 14 June 2017

Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity.

scientific article published on 8 March 2017

Prognostic value of β1 integrin expression in colorectal liver metastases

scientific article published on 15 December 2013

Quantitative proteome profiling of lymph node-positive vs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis

scientific article published on 12 May 2014

Reactivation and persistence of human herpesvirus-8 infection in B cells and monocytes by Th-1 cytokines increased in Kaposi's sarcoma

scientific article published on 01 June 1999

Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice

scientific article published on 5 May 2017

Reverse Transfected Cell Microarrays in Infectious Disease Research

scientific article published on January 1, 2011

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases.

scientific article published on July 2011

SMYD2 targets RIPK1 and restricts TNF-induced apoptosis and necroptosis to support colon tumor growth

scientific article published on 12 January 2022

Serum Concentrations of Fibroblast Growth Factor 2 Are Increased in HIV Type 1-Infected Patients and Inversely Related to Survival Probability

article

Soluble intercellular adhesion molecule-1 is a prognostic marker in colorectal carcinoma.

scientific article

Structural proteins of Kaposi's sarcoma-associated herpesvirus antagonize p53-mediated apoptosis.

scientific article published on 27 January 2014

T17b murine embryonal endothelial progenitor cells can be induced towards both proliferation and differentiation in a fibrin matrix.

scientific article

Tetramerization of human guanylate-binding protein 1 is mediated by coiled-coil formation of the C-terminal α-helices

scientific article

The Ebola virus glycoprotein and HIV-1 Vpu employ different strategies to counteract the antiviral factor tetherin

scientific article

The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor.

scientific article published in July 1999

The clinical value of von Willebrand factor in colorectal carcinomas.

scientific article published on 23 September 2011

The contribution of systems biology and reverse genetics to the understanding of Kaposi's sarcoma-associated herpesvirus pathogenesis in endothelial cells

scientific article

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

scientific article

The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the Toll-like receptor-induced proinflammatory cytokine response

scientific article

The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression

scientific article

The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines.

scientific article

The viral interferon-regulatory factor-3 is required for the survival of KSHV-infected primary effusion lymphoma cells

scientific article

Transcription Pattern of Human Herpesvirus 8 Open Reading Frame K3 in Primary Effusion Lymphoma and Kaposi's Sarcoma.

scientific article

Transcription pattern of human herpesvirus 8 open reading frame K3 in primary effusion lymphoma and Kaposi's sarcoma.

scientific article published in August 2001

Transcriptional activation of endogenous retroviral sequences in human epidermal keratinocytes by UVB irradiation.

scientific article published on October 1999

Tumor-associated fibroblasts isolated from colorectal cancer tissues exhibit increased ICAM-1 expression and affinity for monocytes.

scientific article published on 20 November 2013

Unique features of different members of the human guanylate-binding protein family.

scientific article

Usability and Suitability of the Omics-Integrating Analysis Platform tranSMART for Translational Research and Education.

scientific article published in October 2017

VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis.

scientific article published on 19 March 2015

Validation of the reliability of computational O-GlcNAc prediction

scientific article published on 9 December 2013

Vascular endothelial growth factor production in normal epidermis and in benign and malignant epithelial skin tumors.

scientific article

Viral inhibitor of apoptosis vFLIP/K13 protects endothelial cells against superoxide-induced cell death.

scientific article

β6 -integrin serves as a novel serum tumor marker for colorectal carcinoma

scientific article published on 29 January 2019