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List of works by Sascha Martens

A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins

scientific article published on 07 April 2020

A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy

scientific article published on 01 July 2020

A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress

scientific article published on 27 August 2020

A division of labor in mTORC1 signaling and autophagy

scientific article published on 04 December 2018

Accessory Interaction Motifs in the Atg19 Cargo Receptor Enable Strong Binding to the Clustered Ubiquitin-related Atg8 Protein.

scientific article published on 11 July 2016

Activation and targeting of ATG8 protein lipidation

scientific article published on 05 May 2020

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

scientific article published on 18 August 2017

Autophagy at sea.

scientific article published on 29 July 2013

Beyond Atg8 binding: The role of AIM/LIR motifs in autophagy.

scientific article published on 25 January 2017

C2 domains and membrane fusion

scientific article published on January 2011

Cargo binding to Atg19 unmasks additional Atg8 binding sites to mediate membrane-cargo apposition during selective autophagy.

scientific article published on 6 April 2014

Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation.

scientific article published on 22 March 2017

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

scientific article

Dissecting the role of the Atg12-Atg5-Atg16 complex during autophagosome formation

scientific article published on 15 January 2013

Excluding the unwanted during autophagy

scientific article

FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates

scientific article published on 07 March 2019

Forming giant vesicles with controlled membrane composition, asymmetry, and contents

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HIV-1 Nef membrane association depends on charge, curvature, composition and sequence.

scientific article published on 22 November 2009

How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates

scientific article published on 22 May 2019

How cells coordinate waste removal through their major proteolytic pathways

scientific article published in July 2015

How synaptotagmin promotes membrane fusion.

scientific article

Hrr25 kinase promotes selective autophagy by phosphorylating the cargo receptor Atg19.

scientific article

In vitro systems for Atg8 lipidation

scientific article published on 13 November 2014

Insights into autophagosome biogenesis from in vitro reconstitutions.

scientific article published on 13 April 2016

Intrinsic lipid binding activity of ATG16L1 supports efficient membrane anchoring and autophagy

scientific article published on 01 April 2019

Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells

scientific article published on 25 April 2024

Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells

scientific article

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

scientific article

Mechanism of cargo-directed Atg8 conjugation during selective autophagy.

scientific article published on 23 November 2016

Mechanisms and regulation of autophagosome formation ⬇️

scientific article published on 02 June 2012

Mechanisms of Selective Autophagy

scientific article published on 11 February 2016

Mechanisms of membrane fusion: disparate players and common principles.

scientific article

Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis

scientific journal article

Membrane curvature in synaptic vesicle fusion and beyond.

scientific article

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Necessary, but also Sufficient?

scientific article published on 30 April 2016

Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy.

scientific article published on 28 September 2015

Phasing out the bad-How SQSTM1/p62 sequesters ubiquitinated proteins for degradation by autophagy.

scientific article published on 20 July 2018

Phospholipids in Autophagosome Formation and Fusion

scientific article

Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria

scientific article published on 30 March 2016

Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation

scientific article published on 01 September 2020

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy

scientific article published on 23 April 2021

Role of C2 domain proteins during synaptic vesicle exocytosis

scientific article published on 01 February 2010

Sorting out "non-canonical" autophagy.

scientific article published on 5 February 2018

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii

scientific article

The interferon-inducible GTPases.

scientific article published on January 2006

p62 filaments capture and present ubiquitinated cargos for autophagy

scientific article published on 17 January 2018

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