List of works - Luitgard Nagel-Steger

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

scientific article published on 21 May 2015

A novel, enzymatically active conformation of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I).

scientific article published on 5 March 2002

A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations

scientific article published in March 2017

Amyloid aggregation inhibitory mechanism of arginine-rich D-peptides

scientific article published in January 2014

Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation

scientific article published on 29 May 2015

An Account of Amyloid Oligomers: Facts and Figures Obtained from Experiments and Simulations

scientific article published on 22 February 2016

An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure.

scientific article

Analysis of heterogeneity in molecular weight and shape by analytical ultracentrifugation using parallel distributed computing

scientific article published in January 2009

Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

scientific article published on 30 May 2017

Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.

scientific article published in December 2015

Characterizing the Effect of Multivalent Conjugates Composed of Aβ-Specific Ligands and Metal Nanoparticles on Neurotoxic Fibrillar Aggregation

scientific article published on 12 July 2016

Combining independent drug classes into superior, synergistically acting hybrid molecules.

scientific article published in November 2010

Corrigendum to: Posttranslational Modification of the NADP-Malic Enzyme Involved in C4 Photosynthesis Modulates the Enzymatic Activity during the Day

scientific article published on 24 October 2021

Determinants of structural and functional plasticity of a widely conserved protease chaperone complex

scientific article published on 27 June 2010

Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation

scientific article

Double-strand DNA end-binding and sliding of the toroidal CRISPR-associated protein Csn2.

scientific article published on 26 April 2013

EDTA aggregates induce SYPRO orange-based fluorescence in thermal shift assay

scientific article

Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins

scientific article published on 13 January 2014

Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease

scientific article published on April 2012

Immobilization of homogeneous monomeric, oligomeric and fibrillar Aβ species for reliable SPR measurements

scientific article

Increase of Positive Net Charge and Conformational Rigidity Enhances the Efficacy of d-Enantiomeric Peptides Designed to Eliminate Cytotoxic Aβ Species.

scientific article published on 31 May 2016

Inhibition of amyloid Aβ aggregation by high pressures or specific d-enantiomeric peptides

scientific article published on 14 March 2018

Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide

scientific article published on 5 February 2008

Interaction of the cellular prion protein with raft-like lipid membranes

scientific article published in January 2007

Interference with Amyloid-β Nucleation by Transient Ligand Interaction

scientific article published on 05 June 2019

Modulation of aggregate size- and shape-distributions of the amyloid-beta peptide by a designed beta-sheet breaker

scientific article published on 24 February 2009

Molecular adaptations of NADP-malic enzyme for its function in C4 photosynthesis in grasses

scientific article published on 24 June 2019

Molecular interactions between prions as seeds and recombinant prion proteins as substrates resemble the biological interspecies barrier in vitro

scientific article

Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering

scientific article

Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice

scientific article

Posttranslational Modification of the NADP-Malic Enzyme Involved in C4 Photosynthesis Modulates the Enzymatic Activity during the Day

scientific article published on 30 July 2019

Prevention of Alzheimer's disease-associated Abeta aggregation by rationally designed nonpeptidic beta-sheet ligands

scientific article

QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers

scientific article

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

article

Reduction of Alzheimer's disease amyloid plaque load in transgenic mice by D3, A D-enantiomeric peptide identified by mirror image phage display

scientific article

Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division

scientific article

Seeded fibrillation as molecular basis of the species barrier in human prion diseases

scientific article

Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases

scientific article

Solution-Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies

scientific article published on 22 July 2019

Stoichiometric Zn2+ interferes with the self-association of Aβ42: Insights from size distribution analysis

scientific article published on 21 February 2018

Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association

scientific article published in Scientific Reports

Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response

scientific article published on 03 May 2018

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

scientific article published on 24 November 2017

The Chlamydia pneumoniae Adhesin Pmp21 Forms Oligomers with Adhesive Properties

scientific article published on 22 August 2016

The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.

scientific article published on 22 November 2013

The mammalian autophagy initiator complex contains 2 HORMA domain proteins

scientific article published on 3 August 2015

The off-rate of monomers dissociating from amyloid-β protofibrils

scientific article published on 18 November 2013

Toward the Mode of Action of the Clinical Stage All-d-Enantiomeric Peptide RD2 on Aβ42 Aggregation

scientific article published on 22 November 2019

List of works by Luitgard Nagel-Steger

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

A novel, enzymatically active conformation of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I).

A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations

Amyloid aggregation inhibitory mechanism of arginine-rich D-peptides

Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation

An Account of Amyloid Oligomers: Facts and Figures Obtained from Experiments and Simulations

An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure.

Analysis of heterogeneity in molecular weight and shape by analytical ultracentrifugation using parallel distributed computing

Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.

Characterizing the Effect of Multivalent Conjugates Composed of Aβ-Specific Ligands and Metal Nanoparticles on Neurotoxic Fibrillar Aggregation

Combining independent drug classes into superior, synergistically acting hybrid molecules.

Corrigendum to: Posttranslational Modification of the NADP-Malic Enzyme Involved in C4 Photosynthesis Modulates the Enzymatic Activity during the Day

Determinants of structural and functional plasticity of a widely conserved protease chaperone complex

Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation

Double-strand DNA end-binding and sliding of the toroidal CRISPR-associated protein Csn2.

EDTA aggregates induce SYPRO orange-based fluorescence in thermal shift assay

Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins

Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease

Immobilization of homogeneous monomeric, oligomeric and fibrillar Aβ species for reliable SPR measurements

Increase of Positive Net Charge and Conformational Rigidity Enhances the Efficacy of d-Enantiomeric Peptides Designed to Eliminate Cytotoxic Aβ Species.

Inhibition of amyloid Aβ aggregation by high pressures or specific d-enantiomeric peptides

Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide

Interaction of the cellular prion protein with raft-like lipid membranes

Interference with Amyloid-β Nucleation by Transient Ligand Interaction

Modulation of aggregate size- and shape-distributions of the amyloid-beta peptide by a designed beta-sheet breaker

Molecular adaptations of NADP-malic enzyme for its function in C4 photosynthesis in grasses

Molecular interactions between prions as seeds and recombinant prion proteins as substrates resemble the biological interspecies barrier in vitro

Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering

Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice

Posttranslational Modification of the NADP-Malic Enzyme Involved in C4 Photosynthesis Modulates the Enzymatic Activity during the Day

Prevention of Alzheimer's disease-associated Abeta aggregation by rationally designed nonpeptidic beta-sheet ligands

QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

Reduction of Alzheimer's disease amyloid plaque load in transgenic mice by D3, A D-enantiomeric peptide identified by mirror image phage display

Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division

Seeded fibrillation as molecular basis of the species barrier in human prion diseases

Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases

Solution-Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies

Stoichiometric Zn2+ interferes with the self-association of Aβ42: Insights from size distribution analysis

Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association

Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

The Chlamydia pneumoniae Adhesin Pmp21 Forms Oligomers with Adhesive Properties

The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.

The mammalian autophagy initiator complex contains 2 HORMA domain proteins

The off-rate of monomers dissociating from amyloid-β protofibrils

Toward the Mode of Action of the Clinical Stage All-d-Enantiomeric Peptide RD2 on Aβ42 Aggregation