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List of works by Simon P. Mooijaart

A European Research Agenda for Geriatric Emergency Medicine: a modified Delphi study

scientific article published on 21 November 2020

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

APOE genotype modulates the effect of serum calcium levels on cognitive function in old age.

scientific article published in March 2009

Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals

scientific article published on 7 October 2015

Ambulant 24-h glucose rhythms mark calendar and biological age in apparently healthy individuals

scientific article published on 06 February 2013

An Internet-Based Physical Activity Intervention to Improve Quality of Life of Inactive Older Adults: A Randomized Controlled Trial.

scientific article published on 27 April 2016

ApoE plasma levels and risk of cardiovascular mortality in old age

scientific article published on 9 May 2006

Association Between Glycosylated Hemoglobin and Cardiovascular Events and Mortality in Older Adults without Diabetes Mellitus in the General Population: The Leiden 85-Plus Study

scientific article published on June 2015

Association between changes in brain microstructure and cognition in older subjects at increased risk for vascular disease.

scientific article published on 7 August 2015

Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes.

scientific article

Association of liver enzymes and computed tomography markers of liver steatosis with familial longevity

scientific article (publication date: 2014)

Association of visit-to-visit variability in blood pressure with cognitive function in old age: prospective cohort study

scientific article published on 29 July 2013

Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease

scientific article published on 8 October 2014

Blood Pressure Lowering Medication, Visit-to-Visit Blood Pressure Variability, and Cognitive Function in Old Age.

scientific article published on 8 July 2015

Blood pressure trends and mortality: the Leiden 85-plus Study.

scientific article published in January 2013

Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).

scientific article

C-reactive protein and genetic variants and cognitive decline in old age: the PROSPER study

scientific article (publication date: 2011)

C-reactive protein and glucose regulation in familial longevity

scientific article published on 19 January 2011

CYP2D6 Metabolism in Frail Elderly Compared to Non-Frail Elderly: A Pilot Feasibility Study

scientific article

Characteristics of randomized controlled trials designed for elderly: a systematic review

scientific article published on 15 May 2015

Choosing relevant endpoints for older breast cancer patients in clinical trials: an overview of all current clinical trials on breast cancer treatment

scientific article published on 9 July 2014

Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study

scientific article published on 11 March 2013

Cognitive Testing in People at Increased Risk of Dementia Using a Smartphone App: The iVitality Proof-of-Principle Study

scientific article

Complement Factor H polymorphism Y402H associates with inflammation, visual acuity, and cardiovascular mortality in the elderly population at large

scientific article

Complement factor H Y402H decreases cardiovascular disease risk in patients with familial hypercholesterolaemia

scientific article published on 19 December 2008

Complement receptor 1 gene polymorphisms are associated with cardiovascular risk.

scientific article published on 20 December 2016

Correction: Predictive Value of a Profile of Routine Blood Measurements on Mortality in Older Persons in the General Population: The Leiden 85-Plus Study

scientific article published on 9 June 2015

Correction: The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 7 July 2017

Dose-response effects of a Web-based physical activity program on body composition and metabolic health in inactive older adults: additional analyses of a randomized controlled trial.

scientific article

Effects of a web-based intervention on physical activity and metabolism in older adults: randomized controlled trial.

scientific article

Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity

scientific article published on 29 June 2016

Evaluation of the Use of Home Blood Pressure Measurement Using Mobile Phone-Assisted Technology: The iVitality Proof-of-Principle Study.

scientific article published on 13 June 2016

Executive function, but not memory, associates with incident coronary heart disease and stroke

scientific article published on 5 August 2015

External validity of randomized controlled trials in older adults, a systematic review

scientific article

Familial longevity is marked by enhanced insulin sensitivity

scientific article

Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: the Leiden longevity study

scientific article published in March 2010

Functional and Cognitive Impairment, Frailty, and Adverse Health Outcomes in Older Patients Reaching ESRD-A Systematic Review

scientific article published on 24 June 2016

Functional and cognitive impairment, social environment, frailty and adverse health outcomes in older patients with head and neck cancer, a systematic review

scientific article

Functional and cognitive impairment, social functioning, frailty and adverse health outcomes in older patients with esophageal cancer, a systematic review

scientific article published on 19 April 2018

Genes encoding longevity: from model organisms to humans

scientific article published on 15 January 2008

Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study

scientific article published on 05 May 2006

Genetic variation in galectin-3 gene associates with cognitive function at old age.

scientific article

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genomics of human longevity.

scientific article

Geriatric Screeners 2.0: Time for a Paradigm Shift in Emergency Department Vulnerability Research

scientific article published on 13 May 2020

Geriatric Screening, Triage Urgency, and 30-Day Mortality in Older Emergency Department Patients

scientific article published on 04 April 2020

High Innate Production Capacity of Proinflammatory Cytokines Increases Risk for Death from Cancer: Results of the PROSPER Study

scientific article published on 01 December 2009

High Liver Enzyme Concentrations are Associated with Higher Glycemia, but not with Glycemic Variability, in Individuals without Diabetes Mellitus

scientific article published on 13 September 2017

High serum glucose levels are associated with a higher perceived age.

scientific article published on 20 November 2011

High-Sensitivity Cardiac Troponin Concentration and Risk of First-Ever Cardiovascular Outcomes in 154,052 Participants

scientific article

High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk

scientific article published on 16 February 2016

Homocysteine and familial longevity: the Leiden Longevity Study

scientific article

Human insulin/IGF-1 and familial longevity at middle age.

scientific article

Initial disease severity and quality of care of emergency department sepsis patients who are older or younger than 70 years of age.

scientific article published on 25 September 2017

International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey ⬇️

scientific article

Levels of 25-hydroxyvitamin D in familial longevity: the Leiden Longevity Study

scientific article

Liver X receptor alpha associates with human life span

scientific article published on 01 April 2007

Low blood pressure predicts increased mortality in very old age even without heart failure: the Leiden 85-plus Study.

scientific article published on 17 December 2012

Low serum free triiodothyronine levels mark familial longevity: the Leiden Longevity Study

scientific article published on 16 December 2009

Low thyroid function and anemia in old age: the Leiden 85-plus study

scientific article published on 01 February 2015

Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease

scientific article published on 14 August 2020

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

scientific article published on 12 August 2019

N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk

scientific article published on 9 July 2014

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study.

scientific article published on 17 July 2009

Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997.

scientific article published on 11 December 2017

Physician's Prescribing Preference as an Instrumental Variable: Exploring Assumptions Using Survey Data.

scientific article

Plasma apolipoprotein CI protects against mortality from infection in old age.

scientific article published in February 2008

Plasma levels of apolipoprotein E and cognitive function in old age.

scientific article published in April 2007

Plasma levels of apolipoprotein E and risk of stroke in old age.

scientific article published in April 2007

Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study

scientific article

Predicting mortality in acutely hospitalized older patients: a retrospective cohort study

scientific article published on 29 January 2016

Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study.

scientific article

Predictive value of a profile of routine blood measurements on mortality in older persons in the general population: the Leiden 85-plus Study

scientific article

Predictors and Outcomes of Revisits in Older Adults Discharged from the Emergency Department

scientific article published on 28 February 2018

Proton magnetic resonance spectroscopy shows lower intramyocellular lipid accumulation in middle-aged subjects predisposed to familial longevity.

scientific article published on 15 November 2011

Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines

scientific article published on 30 October 2019

Reduced insulin/IGF-1 signalling and human longevity.

scientific article

Regression Discontinuity Design: Simulation and Application in Two Cardiovascular Trials with Continuous Outcomes.

scientific article

Regression discontinuity was a valid design for dichotomous outcomes in three randomized trials

scientific article published on 24 February 2018

Renal function in familial longevity: the Leiden Longevity Study.

scientific article published on 2 January 2014

Responsiveness of the innate immune system and glucose concentrations in the oldest old.

scientific article published on 11 August 2011

Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study

scientific article published on 18 December 2012

Resting heart rate, heart rate variability and functional decline in old age.

scientific article

Risk stratification and treatment effect of statins in secondary cardiovascular prevention in old age: Additive value of N-terminal pro-B-type natriuretic peptide

scientific article published on 24 November 2015

Secondary phenotype analysis in ascertained family designs: application to the Leiden longevity study ⬇️

scientific article

Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over

scientific article published on 19 September 2018

Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST).

scientific article

Subclinical Thyroid Dysfunction and Depressive Symptoms among the Elderly: A Prospective Cohort Study.

scientific article published on 14 July 2015

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

scientific article

Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk

scholarly article by David Nanchen et al published March 2012 in The Journal of Clinical Endocrinology and Metabolism

Subclinical thyroid dysfunction and cognitive decline in old age

scientific article

Subclinical thyroid dysfunction and functional capacity among elderly.

scientific article

The Cognitive decline in Older Patients with End stage renal disease (COPE) study - rationale and design.

scientific article published on 10 June 2017

The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study

scientific article published on 01 May 2018

The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 10 January 2017

The development, implementation and evaluation of a transitional care programme to improve outcomes of frail older patients after hospitalisation

scientific article published on 13 June 2016

The effect of cognitive impairment on the predictive value of multimorbidity for the increase in disability in the oldest old: the Leiden 85-plus Study

scientific article

The heart-brain connection: a multidisciplinary approach targeting a missing link in the pathophysiology of vascular cognitive impairment.

scientific article

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012

The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes

scientific article published on 17 November 2011

The most commonly used disease severity scores are inappropriate for risk stratification of older emergency department sepsis patients: an observational multi-centre study.

scientific article published on 11 September 2017

Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

scientific article published on 3 April 2017

User preferences and usability of iVitality: optimizing an innovative online research platform for home-based health monitoring

scientific article

VDR gene variants associate with cognitive function and depressive symptoms in old age.

scientific article

Variation in the SHC1 gene and longevity in humans

scientific article (publication date: February 2004)

Variation in the human TP53 gene affects old age survival and cancer mortality.

scientific article

Variation in treatment strategies of Swiss general practitioners for subclinical hypothyroidism in older adults

scientific article published on 28 July 2015

Ventricular Repolarization is Associated with Cognitive Function, but Not with Cognitive Decline and Brain Magnetic Resonance Imaging (MRI) Measurements in Older Adults

scientific article published on 26 March 2020

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