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List of works by Jonathan B. Chaires

"Inside-Out" PEGylation of Bovine β-Cross-Linked Hemoglobin

scientific article published on 20 March 2017

A Discovery Funnel for Nucleic Acid Binding Drug Candidates

scientific article

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

scientific article published on 21 May 2015

A new bisintercalating anthracycline with picomolar DNA binding affinity.

scientific article published on December 2005

A premelting conformational transition in poly(dA)-Poly(dT) coupled to daunomycin binding

scientific article published on 01 March 1989

A small molecule--DNA binding landscape

scientific article published in September 2015

A thermodynamic investigation of the melting of B-Z junction forming DNA oligomers

scientific article published on 01 February 1994

A thermodynamic signature for drug-DNA binding mode

scientific article published on 19 April 2006

Activation of the proapoptotic Bcl-2 protein Bax by a small molecule induces tumor cell apoptosis

scientific article published on 13 January 2014

Allostery: DNA does it, too.

scientific article

An improved model for the hTERT promoter quadruplex

scientific article published on 19 December 2014

An integrated molecular dynamics (MD) and experimental study of higher order human telomeric quadruplexes

scientific article published on June 2010

An investigation of G-quadruplex structural polymorphism in the human telomere using a combined approach of hydrodynamic bead modeling and molecular dynamics simulation

scientific article

An octakis-intercalating molecule

scientific article

Analysis of drug-DNA binding isotherms: a Monte Carlo approach

scientific article published in January 1994

Analysis of multidimensional G-quadruplex melting curves

scientific article

Anthracycline antibiotics. Interaction with DNA and nucleosomes and inhibition of DNA synthesis.

scientific article

Binding of Two Novel Bisdaunorubicins to DNA Studied by NMR Spectroscopy, ⬇️

scientific article published on July 22, 1997

Binding of daunomycin to calf thymus nucleosomes

scientific article published on 01 January 1983

Binding of daunomycin to diaminopurine- and/or inosine-substituted DNA

scientific article published on 01 January 1998

Binding of netropsin to several DNA constructs: evidence for at least two different 1:1 complexes formed from an -AATT-containing ds-DNA construct and a single minor groove binding ligand.

scientific article published on 22 June 2006

Binding: a polemic and rough guide

scientific article published in January 2008

Biocalorimetry

scientific article published on 01 April 2015

Biophysical characterization of the human telomeric (TTAGGG)4 repeat in a potassium solution

scientific article published on 24 March 2007

Biophysical chemistry of the daunomycin-DNA interaction.

scientific article published on April 1990

Calculation of hydrodynamic properties for G-quadruplex nucleic acid structures from in silico bead models

scientific article published in January 2013

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition.

scientific article

Calorimetric analysis of the plasma proteome

scientific article

Calorimetry outside the box: a new window into the plasma proteome.

scientific article

Characterization of Quadruplex DNA Structure by Circular Dichroism.

scientific article published on 2 March 2017

Characterization of a K+-induced conformational switch in a human telomeric DNA oligonucleotide using 2-aminopurine fluorescence

scientific article

Characterization of preferred deoxyribonuclease I cleavage sites

scientific article published on 01 February 1994

Chemical cross-linking of ethidium to DNA by glyoxal

scientific article published on 01 October 1998

Clinical application of plasma thermograms. Utility, practical approaches and considerations.

scientific article

Competition dialysis: an assay to measure the structural selectivity of drug-nucleic acid interactions.

scientific article

Criteria for the mode of binding of DNA binding agents.

scientific article published on June 1995

Daunomycin binding to deoxypolynucleotides with alternating sequences: complete thermodynamic profiles of heterogeneous binding sites

scientific article published on 01 October 2002

Daunomycin binding to detergent micelles: a model system for evaluating the hydrophobic contribution to drug-DNA interactions

scientific article published on 11 September 2007

Daunomycin inhibits the B leads to Z transition in poly d(G-C).

scientific article

Design, synthesis, and evaluation of novel biarylpyrimidines: a new class of ligand for unusual nucleic acid structures

scientific article published on 01 August 2006

Detection of cervical cancer biomarker patterns in blood plasma and urine by differential scanning calorimetry and mass spectrometry

scientific article published on 08 January 2014

Discovery of novel triple helical DNA intercalators by an integrated virtual and actual screening platform

scientific article

Drug--DNA interactions.

scientific article

Effect of O6-methylguanine on the stability of G-quadruplex DNA.

scientific article published in May 2008

Effects of hydration, ion release, and excluded volume on the melting of triplex and duplex DNA

scientific article published on 01 January 1999

Energetics and kinetics of a conformational switch in G-quadruplex DNA

scientific article published on March 2009

Enthalpies of DNA melting in the presence of osmolytes

scientific article published on 21 August 2006

Enthalpy/Entropy Compensation: Influence of DNA Flanking Sequence on the Binding of 7-Amino Actinomycin D to Its Primary Binding Site in Short DNA Duplexes ⬇️

scientific article published on October 21, 2003

Equilibrium studies on the interaction of daunomycin with deoxypolynucleotides

scientific article published on 01 August 1983

Equilibrium unfolding of Bombyx mori glycyl-tRNA synthetase

scientific article published on 30 October 2000

Exploiting anthracycline scaffold for designing DNA-targeting agents

scientific article published on 01 January 2001

Folding Landscape of a Parallel G-Quadruplex

scientific article published on 27 February 2019

Folding and unfolding pathways of the human telomeric G-quadruplex

scientific article published on 31 January 2014

G-quadruplex secondary structure from circular dichroism spectroscopy.

scientific article

G-quadruplex structure and stability illuminated by 2-aminopurine phasor plots

scientific article

Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability.

scientific article

Hydration changes for DNA intercalation reactions

scientific article

Hydration is a major determinant of the G-quadruplex stability and conformation of the human telomere 3' sequence of d(AG3(TTAG3)3)

scientific article published on 18 November 2010

Hydration of drug-DNA complexes: greater water uptake for adriamycin compared to daunomycin

scientific article published on 13 September 2008

Hydrodynamic Models of G-Quadruplex Structures

scientific article published on 19 June 2015

Inhibition of the B to Z transition in poly(dGdC).poly(dGdC) by covalent attachment of ethidium: equilibrium studies

scientific article published in November 1991

Inhibition of the B to Z transition in poly(dGdC).poly(dGdC) by covalent attachment of ethidium: kinetic studies

scientific article published on 01 November 1991

Inhibition of the thermally driven B to Z transition by intercalating drugs

scientific article published on 01 December 1986

Insights from a new analytical electrophoresis apparatus

scientific article published on 01 December 1996

Interaction of an acridine dimer with DNA quadruplex structures.

scientific article

Intercalation of trioxatriangulenium ion in DNA: binding, electron transfer, x-ray crystallography, and electronic structure.

scientific article

Interrogation of the plasma proteome with differential scanning calorimetry

scientific article published on 01 November 2007

Isothermal folding of G-quadruplexes.

scientific article

Kinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures

scientific article published on 21 June 2008

Kinetics of the daunomycin--DNA interaction

scientific article published on 01 January 1985

Linkage of cation binding and folding in human telomeric quadruplex DNA.

scientific article

Long-range allosteric effects on the B to Z equilibrium by daunomycin

article published in 1985

Modeling complex equilibria in isothermal titration calorimetry experiments: thermodynamic parameters estimation for a three-binding-site model

scientific article published on 19 December 2012

Molecular docking of intercalators and groove-binders to nucleic acids using Autodock and Surflex

scientific article published on 22 July 2008

Molecular recognition of a RNA:DNA hybrid structure

scientific article published on 01 July 2001

Molecular recognition of nucleic acids: coralyne binds strongly to poly(A).

scientific article published in September 2005

NB-506, an indolocarbazole topoisomerase I inhibitor, binds preferentially to triplex DNA

scientific article published on 01 March 2000

Neither delta- nor lambda-tris(phenanthroline)ruthenium(II) binds to DNA by classical intercalation

scientific article published on 01 October 1992

Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4

scientific article published on 29 October 2012

Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal

scientific article

Oxazine 170 induces DNA:RNA:DNA triplex formation

scientific article published in May 2005

PCR generation of large amounts of purified DNA.

scientific article published on December 1994

Parsing free energies of drug-DNA interactions.

scientific article published on January 2000

Parsing the free energy of anthracycline antibiotic binding to DNA

scientific article published on 01 February 1996

Polymorphism and resolution of oncogene promoter quadruplex-forming sequences.

scientific article published on 21 September 2011

Populated Intermediates in the Thermal Unfolding of the Human Telomeric Quadruplex ⬇️

scientific article published on September 27, 2012

Possible origin of differences between van't Hoff and calorimetric enthalpy estimates

scientific article published on 01 February 1997

Preface

scientific article published on 01 August 2015

Preface

scientific article published on 01 September 2015

Preferential binding of H1e histone to GC-rich DNA.

scientific article published on January 1994

Preferential binding of daunomycin to 5'ATCG and 5'ATGC sequences revealed by footprinting titration experiments

scientific article published on 01 July 1990

Probing the molecular recognition of a DNA.RNA hybrid duplex

scientific article published on April 2010

Rapid screening of structurally selective ligand binding to nucleic acids

scientific article published on 01 January 2001

Rational selection of small molecules that increase transcription through the GAA repeats found in Friedreich's ataxia.

scientific article published on 15 September 2006

Relaxation kinetics of E coli ribosomes: evidence for the reaction of 30S · IF3 complex with 50s ribosomal subunits ⬇️

scientific article published on May 1, 1979

Relaxation kinetics of E. coli ribosomes ⬇️

scientific article published on November 1, 1977

Self-association of daunomycin

scientific article published on 01 August 1982

Sequence and structural selectivity of nucleic acid binding ligands

scientific article published on 01 December 1999

Sequence dependence of the free energy of B-Z junction formation in deoxyoligonucleotides

scientific article published in May 1993

Sequence specificity of the daunomycin-DNA interaction

scientific article published on 01 May 1988

Sequence- and structural-selective nucleic acid binding revealed by the melting of mixtures.

scientific article

Sequence-Specific DNA Minor Groove Binders. Design and Synthesis of Netropsin and Distamycin Analogues

scientific article published on 01 September 1998

Singular value decomposition of 3-D DNA melting curves reveals complexity in the melting process

scientific article published on 01 January 1997

Site and sequence specificity of the daunomycin-DNA interaction

scientific article published on 01 December 1987

Specific binding of hoechst 33258 to the d(CGCAAATTTGCG)2 duplex: calorimetric and spectroscopic studies ⬇️

scientific article published on August 15, 1997

Stability and kinetics of G-quadruplex structures

scientific article published on 21 August 2008

Statistical analysis of plasma thermograms measured by differential scanning calorimetry

scientific article published on 29 September 2010

Structural selectivity of aromatic diamidines

scientific article published on 01 November 2004

Structure and stability of Z* DNA

scientific article published on 01 June 1988

Structure and stability of higher-order human telomeric quadruplexes

scientific article published in December 2011

Structure of a DNA-bisdaunomycin complex

scientific article

Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid

scientific article published on 01 August 1982

Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: geometry of intercalation of iremycin and daunomycin

scientific article published on 01 August 1982

Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities

scientific article published on 01 July 1999

Sucrose density gradient sedimentation of E. coli ribosomes ⬇️

scientific article published on November 1, 1977

Synthesis and Biological Evaluation of Bisindenoisoquinolines as Topoisomerase I Inhibitors

scientific article (publication date: August 2006)

Targeting DNA

scientific article published on 01 August 2011

Targeting DNA

scientific article published on 14 May 2008

The tail of the telomere

scientific article published in December 2008

Thermal difference spectra: a specific signature for nucleic acid structures.

scientific article

Thermodynamic characterization of human telomere quadruplex unfolding

scientific article published on December 2013

Thermodynamic characterization of the binding of nucleotides to glycyl-tRNA synthetase

scientific article published in May 2003

Thermodynamic studies for drug design and screening

scientific article published on 08 March 2012

Thermodynamics of the B to Z transition in poly(dGdC)

scientific article published on 01 September 1988

Thermodynamics of the daunomycin-DNA interaction: ionic strength dependence of the enthalpy and entropy

scientific article published on 01 February 1985

Tight Binding of the Antitumor Drug Ditercalinium to Quadruplex DNA

scientific article published on 01 December 2002

Triplex selective 2-(2-naphthyl)quinoline compounds: origins of affinity and new design principles

scientific article

Tris(phenanthroline)ruthenium(II) enantiomer interactions with DNA: mode and specificity of binding

scientific article published on 01 March 1993

Ultratight DNA binding of a new bisintercalating anthracycline antibiotic

scientific article published on 01 February 1998

Unraveling the Thermodynamics of the Folding and Interconversion of Human Telomere G-Quadruplexes

scientific article published on 3 August 2016

Use of competition dialysis in the discovery of G-quadruplex selective ligands.

scientific article published on December 2007

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