List of works by Manu Shankar-Hari

A Comparison of Mortality From Sepsis in Brazil and England

article

A dynamic COVID-19 immune signature includes associations with poor prognosis

scientific article published on 17 August 2020

A life-threatening sore throat masquerading as swine flu

scientific article published in The Lancet

Acceptance and transfer to a regional severe respiratory failure and veno-venous extracorporeal membrane oxygenation (ECMO) service: predictors and outcomes.

scientific article published on 23 November 2017

Accounting for Heterogeneity in Relative Treatment Effects for Use in Cost-Effectiveness Models and Value-of-Information Analyses.

scientific article published on 23 February 2015

Activated protein C in severe acute pancreatitis without sepsis? Not just yet ...

scientific article

Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis

scientific article published on 14 March 2017

Acute Respiratory Distress Syndrome Phenotypes and Identifying Treatable Traits. The Dawn of Personalized Medicine for ARDS.

scientific article published in February 2017

Acute respiratory distress syndrome (ARDS) phenotyping

scientific article published on 05 December 2018

An evaluation of the feasibility, cost and value of information of a multicentre randomised controlled trial of intravenous immunoglobulin for sepsis (severe sepsis and septic shock): incorporating a systematic review, meta-analysis and value [...]

scientific article

Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

scientific article

Association of cardiometabolic microRNAs with COVID-19 severity and mortality

scientific article published on 01 January 2022

Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis

scientific article published on 09 September 2020

Author Correction: A dynamic COVID-19 immune signature includes associations with poor prognosis

scientific article published on 27 November 2020

Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective

scientific article published on 12 December 2012

COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland

scientific article published on 09 October 2020

Can Concurrent Abnormalities in Free Light Chains and Immunoglobulin Concentrations Identify a Target Population for Immunoglobulin Trials in Sepsis?

scientific article

Caring for Sepsis Patients: An Update

scientific article published on 19 October 2017

Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study.

scientific article

Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y12 Inhibition

scientific article published on 21 April 2020

Continuous renal replacement therapy (CRRT) in patients with liver disease: is circuit life different?

scientific article

Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials

scientific article published on 20 July 2020

Current gaps in sepsis immunology: new opportunities for translational research

scientific article published on 17 October 2019

Defining Septic Shock—Reply

scientific article published in The Journal of the American Medical Association

Demographic Shifts, Case Mix, Activity, and Outcome for Elderly Patients Admitted to Adult General ICUs in the United Kingdom, Wales, and Northern Ireland

scholarly article by Andrew Jones published in January 2020

Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

scientific article

Differences in Impact of Definitional Elements on Mortality Precludes International Comparisons of Sepsis Epidemiology-A Cohort Study Illustrating the Need for Standardized Reporting

scientific article published on 27 June 2016

Divide and conquer: identifying acute respiratory distress syndrome subphenotypes.

scientific article published on 17 July 2017

Do Sepsis-3 Criteria Facilitate Earlier Recognition of Sepsis and Septic Shock? A Retrospective Cohort Study

scientific article published on 01 March 2019

Do we need a new definition of sepsis?

scientific article published on 3 February 2015

Early PREdiction of Severe Sepsis (ExPRES-Sepsis) study: protocol for an observational derivation study to discover potential leucocyte cell surface biomarkers

scientific article published on August 2016

Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study

scientific article published on 05 October 2018

Endogenous IgG hypogammaglobulinaemia in critically ill adults with sepsis: systematic review and meta-analysis.

scientific article published on 14 May 2015

Epidemiology of sepsis and septic shock in critical care units: comparison between sepsis-2 and sepsis-3 populations using a national critical care database.

scientific article published in October 2017

Estimating attributable fraction of mortality from sepsis to inform clinical trials.

scientific article published on 25 January 2018

Evidence for a causal link between sepsis and long-term mortality: a systematic review of epidemiologic studies

scientific article

Fatal cardiovascular instability secondary to hypercalcaemia and intracellular calcium deposition complicating T-cell leukaemia-lymphoma.

scientific article published on 3 May 2016

Focus on sepsis

scientific article published on 02 July 2019

Genetic mechanisms of critical illness in Covid-19

scientific article published on 11 December 2020

Healthcare-associated bloodstream infections in critically ill patients: descriptive cross-sectional database study evaluating concordance with clinical site isolates.

scientific article

Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

scientific article published on 03 May 2019

How could we enhance translation of sepsis immunology to inform immunomodulation trials in sepsis?

scientific article published on 26 May 2017

How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?

scientific article published on 01 April 2014

Immune Activation in Sepsis

scientific article published on 12 October 2017

Immunoglobulins and sepsis

scientific article

Influence of aetiology of acute respiratory distress syndrome and early differences in oxygenation on outcome

scientific article published in March 2010

International survey on the management of mechanical ventilation during ECMO in adults with severe respiratory failure.

scientific article published on 30 June 2015

Intravenous immunoglobulin for severe sepsis and septic shock: clinical effectiveness, cost-effectiveness and value of a further randomised controlled trial

scientific article

Judging quality of current septic shock definitions and criteria

scientific article

Just Because Things Are Not Different, Does Not Mean They Are the Same: Biomarker Patterns in Acute Respiratory Distress Syndrome

scientific article

Lessons From ARDS for Non-ARDS Research: Remembrance of Trials Past

scientific article published in The Journal of the American Medical Association

Long-term adherence to a 5 day antibiotic course guideline for treatment of intensive care unit (ICU)-associated Gram-negative infections

scientific article published on 25 February 2014

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

scientific article published on 26 October 2020

Lung Recruitability in Severe Acute Respiratory Distress Syndrome Requiring Extracorporeal Membrane Oxygenation

scientific article published on 01 September 2019

Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study.

scientific article published on 17 April 2018

Major surgery and the immune system: from pathophysiology to treatment

article

Maternal Risk Modeling in Critical Care-Development of a Multivariable Risk Prediction Model for Death and Prolonged Intensive Care

scientific article published on 13 March 2020

Neurogenic diabetes insipidus presenting in a patient with subacute liver failure: a case report

scientific article published on 30 July 2010

Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection

scientific article published on 18 August 2020

Population enrichment for critical care trials: phenotypes and differential outcomes

scientific article published on 01 October 2019

Predictive value of cell-surface markers in infections in critically ill patients: protocol for an observational study (ImmuNe FailurE in Critical Therapy (INFECT) Study).

scientific article published on 18 July 2016

Prevalence of Gram-negative bacilli resistance in adult critically ill patients at admission screening

scientific article published on 11 March 2011

Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies

scientific article

Quantitative assessment of the effects of therapeutic hypothermia on early repolarization in idiopathic ventricular fibrillation survivors: a 7-year cohort study

scientific article published in January 2014

Race, Ethnicity, and Sepsis

scientific article published on 01 June 2018

Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis

scientific article published on 23 January 2020

Readmission Diagnoses After Pediatric Severe Sepsis Hospitalization

scientific article published on 01 April 2019

Redox state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis

scientific article

Relationship between Anaemia, Haemolysis, Inflammation and Haem Oxygenase-1 at Admission with Sepsis: a pilot study

scientific article published in Scientific Reports

Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation

scientific article published on 28 April 2020

Risk Factors at Index Hospitalization Associated With Longer-term Mortality in Adult Sepsis Survivors

scientific article published on 03 May 2019

Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex

scientific article published in 2022

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

scientific article published on 07 June 2021

Sepsis hysteria: excess hype and unrealistic expectations

scientific article published on 01 October 2019

Septic shock resuscitation in the first hour

scientific article published on 11 October 2017

Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis?

scientific article published on 28 October 2019

Statin therapy in critical illness: an international survey of intensive care physicians' opinions, attitudes and practice

scientific article published on 28 June 2012

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis

scientific article published on 14 February 2019

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

scientific article

The diagnostic and prognostic significance of monitoring blood levels of immature neutrophils in patients with systemic inflammation.

scientific article

The influence of statin exposure on inflammatory markers in patients with early bacterial infection: pilot prospective cohort study

scientific article

The intensive care medicine research agenda on septic shock

scientific article

The use of enrichment to reduce statistically indeterminate or negative trials in critical care

scientific article published on 20 March 2017

Trends in Intensive Care for Patients with COVID-19 in England, Wales and Northern Ireland

scientific article published on 11 December 2020

Trials on oxygen supplementation in sepsis: better late than never

scientific article published on 26 November 2019

Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges

scientific article

Use of Hydrocortisone Based on Plasma Biomarkers in Patients with Septic Shock: Another One Bites the Dust?

scientific article published on 01 September 2020

Using Bayesian Methods to Augment the Interpretation of Critical Care Trials: An Overview of Theory and Example Reanalysis of the Alveolar Recruitment Trial

scientific article published on 03 December 2020

Utility of an antibiotic guideline in hospital-associated infections

scientific article published in March 2010

qSOFA, Cue Confusion

scientific article published on 6 February 2018

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