List of works - Kylie M. Wagstaff

A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

scientific article

An AlphaScreen®-based assay for high-throughput screening for specific inhibitors of nuclear import.

scientific article published on February 2011

Author Correction: Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

scientific article published in Scientific Reports

Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting

scientific article published on 08 May 2018

Efficient gene delivery using reconstituted chromatin enhanced for nuclear targeting.

scientific article

Enhanced tumour cell nuclear targeting in a tumour progression model

scientific article

Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner

scientific article published on 6 April 2015

Global enhancement of nuclear localization‐dependent nuclear transport in transformed cells ⬇️

scientific article published on December 12, 2011

Histone-mediated transduction as an efficient means for gene delivery.

scientific article published on 27 February 2007

Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening

scientific article published on 11 January 2018

Interactome of the inhibitory isoform of the nuclear transporter Importin 13.

scientific article

Interactome of the negative regulator of nuclear import BRCA1-binding protein 2

scientific article

Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress

scientific article

Intramolecular masking of nuclear localization signals: analysis of importin binding using a novel AlphaScreen-based method

scientific article published on 7 November 2005

Investigating dengue virus nonstructural protein 5 (NS5) nuclear import.

scientific article published on January 2014

Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus ⬇️

scientific article published on May 1, 2012

Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import

Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

scientific article published on 24 March 2019

Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design.

scientific article published on 18 December 2017

Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.

scientific article

Nuclear drug delivery to target tumour cells.

scientific article published on 15 October 2009

Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication

scientific article published on 22 October 2013

Nuclear import of β-dystroglycan is facilitated by ezrin-mediated cytoskeleton reorganization

scientific article

Nuclear localization and secretion competence are conserved among henipavirus matrix proteins.

scientific article published on 5 January 2017

Nuclear localization of the dystrophin-associated protein α-dystrobrevin through importin α2/β1 is critical for interaction with the nuclear lamina/maintenance of nuclear integrity.

scientific article published on 30 January 2015

Nuclear trafficking of proteins from RNA viruses: potential target for antivirals?

scientific article published on 28 June 2012

Nucleocytoplasmic shuttling of the Duchenne muscular dystrophy gene product dystrophin Dp71d is dependent on the importin α/β and CRM1 nuclear transporters and microtubule motor dynein.

scientific article published on 30 January 2014

Nucleocytoplasmic shuttling of the West Nile virus RNA-dependent RNA polymerase NS5 is critical to infection.

scientific article

Nucleocytoplasmic transport of DNA: enhancing non-viral gene transfer.

scientific article published on September 2007

Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization.

scientific article published in August 2014

PKA-site phosphorylation of importin13 regulates its subcellular localization and nuclear transport function

scientific article published on 31 August 2018

Protein transduction: cell penetrating peptides and their therapeutic applications

scientific article

Quantitative analysis of localization and nuclear aggregate formation induced by GFP-lamin A mutant proteins in living HeLa cells.

scientific article published on July 2006

Quantitative analysis of protein-protein interactions by native page/fluorimaging.

scientific article published in July 2005

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

scientific article published on 10 January 2018

Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells

scientific article

Targeted delivery to the nucleus.

scientific article published on 4 July 2007

The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins

scientific article

The C-terminus of apoptin represents a unique tumor cell-enhanced nuclear targeting module

scientific article published on 01 December 2008

The N-terminal basic domain of the HIV-1 matrix protein does not contain a conventional nuclear localization sequence but is required for DNA binding and protein self-association.

scientific article published on 29 January 2008

The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

scientific article

Transcriptomic profile dataset of embryonic stem cells (Wild-type and IPO13-Knock Out) with and without oxidative stress

publication published on 28 March 2022

Tumor cell-specific photothermal killing by SELEX-derived DNA aptamer-targeted gold nanorods.

scientific article published on 8 December 2015

List of works by Kylie M. Wagstaff

A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

An AlphaScreen®-based assay for high-throughput screening for specific inhibitors of nuclear import.

Author Correction: Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting

Efficient gene delivery using reconstituted chromatin enhanced for nuclear targeting.

Enhanced tumour cell nuclear targeting in a tumour progression model

Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner

Global enhancement of nuclear localization‐dependent nuclear transport in transformed cells ⬇️

Histone-mediated transduction as an efficient means for gene delivery.

Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening

Interactome of the inhibitory isoform of the nuclear transporter Importin 13.

Interactome of the negative regulator of nuclear import BRCA1-binding protein 2

Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress

Intramolecular masking of nuclear localization signals: analysis of importin binding using a novel AlphaScreen-based method

Investigating dengue virus nonstructural protein 5 (NS5) nuclear import.

Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus ⬇️

Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import

Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design.

Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.

Nuclear drug delivery to target tumour cells.

Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication

Nuclear import of β-dystroglycan is facilitated by ezrin-mediated cytoskeleton reorganization

Nuclear localization and secretion competence are conserved among henipavirus matrix proteins.

Nuclear localization of the dystrophin-associated protein α-dystrobrevin through importin α2/β1 is critical for interaction with the nuclear lamina/maintenance of nuclear integrity.

Nuclear trafficking of proteins from RNA viruses: potential target for antivirals?

Nucleocytoplasmic shuttling of the Duchenne muscular dystrophy gene product dystrophin Dp71d is dependent on the importin α/β and CRM1 nuclear transporters and microtubule motor dynein.

Nucleocytoplasmic shuttling of the West Nile virus RNA-dependent RNA polymerase NS5 is critical to infection.

Nucleocytoplasmic transport of DNA: enhancing non-viral gene transfer.

Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization.

PKA-site phosphorylation of importin13 regulates its subcellular localization and nuclear transport function

Protein transduction: cell penetrating peptides and their therapeutic applications

Quantitative analysis of localization and nuclear aggregate formation induced by GFP-lamin A mutant proteins in living HeLa cells.

Quantitative analysis of protein-protein interactions by native page/fluorimaging.

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells

Targeted delivery to the nucleus.

The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins

The C-terminus of apoptin represents a unique tumor cell-enhanced nuclear targeting module

The N-terminal basic domain of the HIV-1 matrix protein does not contain a conventional nuclear localization sequence but is required for DNA binding and protein self-association.

The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

Transcriptomic profile dataset of embryonic stem cells (Wild-type and IPO13-Knock Out) with and without oxidative stress

Tumor cell-specific photothermal killing by SELEX-derived DNA aptamer-targeted gold nanorods.