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List of works by Philipp Sasse

Activity of complex III of the mitochondrial electron transport chain is essential for early heart muscle cell differentiation

scientific article

Adult germ line stem cells as a source of functional neurons and glia

scientific article

Cardiac conduction disturbances and differential effects on atrial and ventricular electrophysiological properties in desmin deficient mice

scientific article published on 01 August 2010

Cardiomyocytes obtained from induced pluripotent stem cells with long-QT syndrome 3 recapitulate typical disease-specific features in vitro

scientific article

Cellular cardiomyoplasty in a transgenic mouse model

scientific article published on 01 February 2002

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels

scientific article published on 05 April 2013

Differential Role of bFGF and VEGF for Vasculogenesis

scientific article published on 01 January 2002

Diversity of Ca2+ signaling in developing cardiac cells.

scientific article published on October 2006

EBIO Does Not Induce Cardiomyogenesis in Human Pluripotent Stem Cells but Modulates Cardiac Subtype Enrichment by Lineage-Selective Survival.

scientific article published on 4 January 2017

Engineered Context-Sensitive Agonism: Tissue-Selective Drug Signaling through a G Protein-Coupled Receptor

scientific article published on 15 November 2016

Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia

scientific article published in Nature

Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium

scientific article

Enhanced heterogeneity of myocardial conduction and severe cardiac electrical instability in annexin A7-deficient mice

scientific article published on 06 July 2007

Enrichment and terminal differentiation of striated muscle progenitors in vitro

scientific article

Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation.

scientific article published on 6 December 2017

Frequency-dependent drug screening using optogenetic stimulation of human iPSC-derived cardiomyocytes.

scientific article

Functional expression of the Na+/Ca2+ exchanger in the embryonic mouse heart

scientific article published on 8 December 2006

Human Connexin43E42K mutation from a sudden infant death victim leads to impaired ventricular activation and neonatal death in mice

scientific article published on 10 December 2014

Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction

scientific article

Improved heart repair upon myocardial infarction: Combination of magnetic nanoparticles and tailored magnets strongly increases engraftment of myocytes.

scientific article published on 15 November 2017

Induction of pluripotency in adult unipotent germline stem cells

scientific article published in July 2009

Intracellular Ca2+ oscillations, a potential pacemaking mechanism in early embryonic heart cells

scientific article published on August 2007

Local Gene Targeting and Cell Positioning Using Magnetic Nanoparticles and Magnetic Tips: Comparison of Mathematical Simulations with Experiments ⬇️

scientific article published on December 30, 2011

Loss of annexin A7 leads to alterations in frequency-induced shortening of isolated murine cardiomyocytes

scientific article

Membrane potential dependent modulations of calcium oscillations in insulin-secreting INS-1 cells.

scientific article

MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization

scientific article

Modeling long QT syndromes using induced pluripotent stem cells: current progress and future challenges.

scientific article published on 21 December 2012

Modulation of L-type Ca(2+) channel current density and inactivation by beta-adrenergic stimulation during murine cardiac embryogenesis

scientific article published on 24 October 2008

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion

scientific article

NCX current in the murine embryonic heart: development-dependent regulation by Na+

scientific article published on 01 March 2007

Neuronal connexin-36 can functionally replace connexin-45 in mouse retina but not in the developing heart.

scientific article published on October 2010

Oct4-induced pluripotency in adult neural stem cells.

scientific article

Optical pacing of the heart: the long way to enlightenment

scientific article published on 01 October 2011

Optogenetic activation of Gq signalling modulates pacemaker activity of cardiomyocytes

scientific article published on 27 February 2014

Optogenetic cardiac pacemakers: science or fiction?

scientific article published on 30 October 2014

Optogenetic control of contractile function in skeletal muscle

scientific article

Optogenetic control of heart muscle in vitro and in vivo

scientific article published on 03 October 2010

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations.

scientific article

Optogenetic stimulation of G-signaling in the heart with high spatio-temporal precision

scientific article published on 20 March 2019

Optogenetic termination of atrial fibrillation in mice.

scientific article published on 23 December 2017

Perlecan is critical for heart stability.

scientific article published on 10 August 2008

Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart

scientific article

Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling

scientific article

S100A1 enhances the L-type Ca2+ current in embryonic mouse and neonatal rat ventricular cardiomyocytes

scientific article

Scalable Electrophysiological Investigation of iPS Cell-Derived Cardiomyocytes Obtained by a Lentiviral Purification Strategy

scientific article published on 8 January 2015

Selective optogenetic control of G<sub>q</sub> signaling using human Neuropsin

scientific article published on 01 April 2022

Spot light on skeletal muscles: optogenetic stimulation to understand and restore skeletal muscle function.

scientific article published on 16 September 2017

Sympathetic control of cardiac output by noradrenaline: quasi-synaptic quantal release or interstitial diffusion and spillover?

scientific article published on 10 May 2018

Synchronization of excitable cardiac cultures of different origin

scientific article published on 23 June 2017

Systemic gene transfer enables optogenetic pacing of mouse hearts.

scientific article published on 12 January 2015

The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans.

scientific article

Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation.

scientific article published on May 2015

beta(2)-adrenoceptor antagonist ICI 118,551 decreases pulmonary vascular tone in mice via a G(i/o) protein/nitric oxide-coupled pathway.

scientific article published on 26 May 2009

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