List of works - Franck Perez

"Antibodies--Europe. Engineering the next generation of antibodies".

scientific article published in March 2008

8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis

scientific article

A dimerized single-chain variable fragment system for the assessment of neutralizing activity of phage display-selected antibody fragments specific for cytomegalovirus

scientific article

A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.

scientific article published on 29 December 2015

A multi-Fc-species system for recombinant antibody production

scientific article

A plus-end raft to control microtubule dynamics and function

scientific article

A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint

scientific article

A siRNA screen identifies RAD21, EIF3H, CHRAC1 and TANC2 as driver genes within the 8q23, 8q24.3 and 17q23 amplicons in breast cancer with effects on cell growth, survival and transformation

scientific article published on 22 October 2013

Analysis of de novo Golgi complex formation after enzyme-based inactivation

scientific article

Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport

scientific article

Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy

scientific article published on 10 October 2019

Bacterial cytoplasm as an effective cell compartment for producing functional VHH-based affinity reagents and Camelidae IgG-like recombinant antibodies

scientific article

CCR5 adopts three homodimeric conformations that control cell surface delivery.

scientific article

CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics

scientific article

CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein belonging to the CLIP-170 family

scientific article

CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development

scientific article published in April 2013

Characterization of single chain antibody targets through yeast two hybrid

scientific article

Control of protein trafficking by reversible masking of transport signals

scientific article

Delivery of antibodies to the cytosol: debunking the myths

scientific article

Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs

scientific article

Direct selection of monoclonal phosphospecific antibodies without prior phosphoamino acid mapping

scientific article

Diversifying the secretory routes in neurons

scientific article

Dymeclin deficiency causes postnatal microcephaly, hypomyelination and reticulum-to-Golgi trafficking defects in mice and humans

scientific article published on 4 February 2015

ESCRT machinery is required for plasma membrane repair

scientific article published on 30 January 2014

Fluorescence-based analysis of trafficking in mammalian cells

scientific article published on January 2013

Fully in vitro selection of recombinant antibodies

scientific article

Golgi trafficking defects in postnatal microcephaly: The evidence for "Golgipathies".

scientific article

Hodgkin and Reed-Sternberg cell-associated autoantigen CLIP-170/restin is a marker for dendritic cells and is involved in the trafficking of macropinosomes to the cytoskeleton, supporting a function-based concept of Hodgkin and Reed-Sternberg cells

scientific article

Identification of G protein alpha subunit-palmitoylating enzyme

scientific article

Identification of pharmacological agents that induce HMGB1 release

scientific article

Identification of pharmacological inhibitors of conventional protein secretion

scientific article published in Scientific Reports

Imaging GTP-bound tubulin: from cellular to in vitro assembled microtubules

scientific article published on January 2013

Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells

scientific article

Interplay between microtubule dynamics and intracellular organization

scientific article

Intrabodies, potent tools to unravel the function and dynamics of intracellular proteins

scientific article published in December 2009

Kinesin is involved in protecting nascent microtubules from disassembly after recovery from nocodazole treatment

scientific article

Kinesin-1 regulates microtubule dynamics via a c-Jun N-terminal kinase-dependent mechanism

scientific article

Laser induced wounding of the plasma membrane and methods to study the repair process

scientific article published on 8 January 2015

Local palmitoylation cycles define activity-regulated postsynaptic subdomains

scientific article

Localized Mechanical Stress Promotes Microtubule Rescue.

scientific article published on 22 November 2016

Methods in Cell Biology. Methods for analysis of Golgi complex function. Preface

scientific article published in January 2013

Microtubule-independent secretion requires functional maturation of Golgi elements

scientific article published on 13 July 2016

NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.

scientific article

Nanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts

scientific article

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

scientific article published on 10 November 2020

Organelles under light control

journal article; published in Nature on 2015-01-07

Phospholipase C γ1 regulates early secretory trafficking and cell migration via interaction with p115.

scientific article published on 22 April 2015

Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus

scientific article published on 28 May 2018

Physico-chemical and biological considerations for membrane wound evolution and repair in animal cells

scientific article

Plasma membrane repair: the adaptable cell life-insurance

scientific article

Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport ⬇️

scientific article published on July 18, 2011

Protein interaction mapping: a Drosophila case study

scientific article published on 14 February 2005

RAB6 and microtubules restrict protein secretion to focal adhesions

scientific article published on 29 May 2019

Rab1 defines a novel pathway connecting the pre-Golgi intermediate compartment with the cell periphery

scientific article

Rab6A and Rab6A' GTPases play non-overlapping roles in membrane trafficking

scientific article

Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170

scientific article (publication date: 28 June 2002)

Recombinant Antibodies to the Small GTPase Rab6 as Conformation Sensors ⬇️

scientific article published on May 9, 2003

Recombinant antibodies against subcellular fractions used to track endogenous Golgi protein dynamics in vivo

scientific article

Recruitment of LC3 to damaged Golgi apparatus

scientific article published on 22 October 2018

Regulation of eIF4F translation initiation complex by the peptidyl prolyl isomerase FKBP7 in taxane-resistant prostate cancer

scientific article published on 15 October 2018

Resolving bundled microtubules using anti-tubulin nanobodies.

scientific article published on 11 August 2015

Role of tetanus neurotoxin insensitive vesicle-associated membrane protein in membrane domains transport and homeostasis

scientific article published in January 2015

Selection and Use of Intracellular Antibodies (Intrabodies) ⬇️

scientific article published on January 1, 2012

Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly.

scientific article

Shigella effector IpaB-induced cholesterol relocation disrupts the Golgi complex and recycling network to inhibit host cell secretion

scientific article

Specific GFP-binding artificial proteins (αRep): a new tool for in vitro to live cell applications

scientific article published on 12 June 2015

Synchronization of secretory cargos trafficking in populations of cells

scientific article published on January 2014

Synchronization of secretory protein traffic in populations of cells

scientific article published on 11 March 2012

Synchronizing Protein Transport in the Secretory Pathway ⬇️

scientific article published on 01 December 2012

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export

scientific article

Targeting CCR5 trafficking to inhibit HIV-1 infection

scientific article published on 16 October 2019

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

scientific article

The gene responsible for Dyggve-Melchior-Clausen syndrome encodes a novel peripheral membrane protein dynamically associated with the Golgi apparatus

scientific article

The many routes of Golgi-dependent trafficking

scientific article published on 12 July 2013

The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis

scientific article

The role of microtubules in secretory protein transport

scientific article published on 29 January 2020

The young and happy marriage of membrane traffic and cell polarity

scientific article published on 10 July 2012

Transmembrane domains control exclusion of membrane proteins from clathrin-coated pits

scientific article published on 7 September 2010

Uncoupling of dynamin polymerization and GTPase activity revealed by the conformation-specific nanobody dynab

scientific article published on 12 October 2017

Whole-cell biopanning with a synthetic phage display library of nanobodies enabled the recovery of follicle-stimulating hormone receptor inhibitors

scientific article published on 7 October 2017

γ-Tubulin Ring Complexes and EB1 play antagonistic roles in microtubule dynamics and spindle positioning

scientific journal article

List of works by Franck Perez

"Antibodies--Europe. Engineering the next generation of antibodies".

8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis

A dimerized single-chain variable fragment system for the assessment of neutralizing activity of phage display-selected antibody fragments specific for cytomegalovirus

A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.

A multi-Fc-species system for recombinant antibody production

A plus-end raft to control microtubule dynamics and function

A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint

A siRNA screen identifies RAD21, EIF3H, CHRAC1 and TANC2 as driver genes within the 8q23, 8q24.3 and 17q23 amplicons in breast cancer with effects on cell growth, survival and transformation

Analysis of de novo Golgi complex formation after enzyme-based inactivation

Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport

Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy

Bacterial cytoplasm as an effective cell compartment for producing functional VHH-based affinity reagents and Camelidae IgG-like recombinant antibodies

CCR5 adopts three homodimeric conformations that control cell surface delivery.

CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics

CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein belonging to the CLIP-170 family

CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development

Characterization of single chain antibody targets through yeast two hybrid

Control of protein trafficking by reversible masking of transport signals

Delivery of antibodies to the cytosol: debunking the myths

Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs

Direct selection of monoclonal phosphospecific antibodies without prior phosphoamino acid mapping

Diversifying the secretory routes in neurons

Dymeclin deficiency causes postnatal microcephaly, hypomyelination and reticulum-to-Golgi trafficking defects in mice and humans

ESCRT machinery is required for plasma membrane repair

Fluorescence-based analysis of trafficking in mammalian cells

Fully in vitro selection of recombinant antibodies

Golgi trafficking defects in postnatal microcephaly: The evidence for "Golgipathies".

Hodgkin and Reed-Sternberg cell-associated autoantigen CLIP-170/restin is a marker for dendritic cells and is involved in the trafficking of macropinosomes to the cytoskeleton, supporting a function-based concept of Hodgkin and Reed-Sternberg cells

Identification of G protein alpha subunit-palmitoylating enzyme

Identification of pharmacological agents that induce HMGB1 release

Identification of pharmacological inhibitors of conventional protein secretion

Imaging GTP-bound tubulin: from cellular to in vitro assembled microtubules

Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells

Interplay between microtubule dynamics and intracellular organization

Intrabodies, potent tools to unravel the function and dynamics of intracellular proteins

Kinesin is involved in protecting nascent microtubules from disassembly after recovery from nocodazole treatment

Kinesin-1 regulates microtubule dynamics via a c-Jun N-terminal kinase-dependent mechanism

Laser induced wounding of the plasma membrane and methods to study the repair process

Local palmitoylation cycles define activity-regulated postsynaptic subdomains

Localized Mechanical Stress Promotes Microtubule Rescue.

Methods in Cell Biology. Methods for analysis of Golgi complex function. Preface

Microtubule-independent secretion requires functional maturation of Golgi elements

NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.

Nanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

Organelles under light control

Phospholipase C γ1 regulates early secretory trafficking and cell migration via interaction with p115.

Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus

Physico-chemical and biological considerations for membrane wound evolution and repair in animal cells

Plasma membrane repair: the adaptable cell life-insurance

Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport ⬇️

Protein interaction mapping: a Drosophila case study

RAB6 and microtubules restrict protein secretion to focal adhesions

Rab1 defines a novel pathway connecting the pre-Golgi intermediate compartment with the cell periphery

Rab6A and Rab6A' GTPases play non-overlapping roles in membrane trafficking

Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170

Recombinant Antibodies to the Small GTPase Rab6 as Conformation Sensors ⬇️

Recombinant antibodies against subcellular fractions used to track endogenous Golgi protein dynamics in vivo

Recruitment of LC3 to damaged Golgi apparatus

Regulation of eIF4F translation initiation complex by the peptidyl prolyl isomerase FKBP7 in taxane-resistant prostate cancer

Resolving bundled microtubules using anti-tubulin nanobodies.

Role of tetanus neurotoxin insensitive vesicle-associated membrane protein in membrane domains transport and homeostasis

Selection and Use of Intracellular Antibodies (Intrabodies) ⬇️

Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly.

Shigella effector IpaB-induced cholesterol relocation disrupts the Golgi complex and recycling network to inhibit host cell secretion

Specific GFP-binding artificial proteins (αRep): a new tool for in vitro to live cell applications

Synchronization of secretory cargos trafficking in populations of cells

Synchronization of secretory protein traffic in populations of cells

Synchronizing Protein Transport in the Secretory Pathway ⬇️

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export

Targeting CCR5 trafficking to inhibit HIV-1 infection

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

The gene responsible for Dyggve-Melchior-Clausen syndrome encodes a novel peripheral membrane protein dynamically associated with the Golgi apparatus

The many routes of Golgi-dependent trafficking

The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis

The role of microtubules in secretory protein transport

The young and happy marriage of membrane traffic and cell polarity

Transmembrane domains control exclusion of membrane proteins from clathrin-coated pits

Uncoupling of dynamin polymerization and GTPase activity revealed by the conformation-specific nanobody dynab