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List of works by Laurens A van Meeteren

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

scientific article

Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid

scientific article published on March 18, 2011

Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting

scientific article published on 5 April 2012

Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D.

scientific article

Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma

scientific article published in January 2007

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

scientific article published on July 2006

Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis

scientific article published on 12 January 2009

Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis

scientific article

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

scientific article

ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis

scientific article published on 28 January 2014

GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2

scientific article published on July 28, 2013

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate

scientific article (publication date: 3 June 2005)

Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein

scientific article

NRP1 presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation.

scientific article published on 20 March 2014

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

scientific article published on 29 July 2008

Regulation and biological activities of the autotaxin-LPA axis.

scientific article published on 16 March 2007

Regulation of endothelial cell plasticity by TGF-β

scientific article published on August 25, 2011

Spider and bacterial sphingomyelinases D target cellular lysophosphatidic acid receptors by hydrolyzing lysophosphatidylcholine.

scientific article

Structural basis of substrate discrimination and integrin binding by autotaxin

scientific article

Suppression of the p53-dependent replicative senescence response by lysophosphatidic acid signaling

scientific article

Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.

scientific article published on July 2005

TGF-β receptor signaling pathways in angiogenesis; emerging targets for anti-angiogenesis therapy.

scientific article published on December 2011

The ins and outs of lysophosphatidic acid signaling.

scientific article published in August 2004

The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans

scientific article published on 13 November 2012

Upregulation of cytokine expression in fibroblasts exposed to loxosceles sphingomyelinase D: what is the trigger?

scientific article published on 08 March 2007

Vascular endothelial growth factor B controls endothelial fatty acid uptake.

scientific article published on 14 March 2010