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List of works by Alfredo Berzal-Herranz

2'-Hydroxyl groups important for exon polymerization and reverse exon ligation reactions catalyzed by a group I ribozyme

scientific article published on 01 September 1993

Activity of core-modified 10-23 DNAzymes against HCV.

scientific article

An experimental method for selecting effective target sites and designing hairpin ribozymes.

scientific article published in January 2004

Analysis of the mechanism of action of the antisense RNA that controls the replication of the repABC plasmid p42d

scientific article published on 30 April 2010

Anchoring hairpin ribozymes to long target RNAs by loop-loop RNA interactions

scientific article published on 01 February 2002

Aptamers: Biomedical Interest and Applications

scientific article published on 16 March 2017

Comparative kinetic analysis of structural variants of the hairpin ribozyme reveals further potential to optimize its catalytic performance.

scientific article published in October 1999

Control of replication of plasmid R1: the intergenic region between copA and repA modulates the level of expression of repA.

scientific article published on January 1991

Design and optimization of sequence-specific hairpin ribozymes

scientific article published on 01 January 2004

Detection of immune response activation by exogenous nucleic acids by a multiplex RT-PCR method.

scientific article published on 4 March 2014

Determination of HCV RNA concentration by direct quantitation of the products from a single RT-PCR.

scientific article published on December 1997

DnaA dependent replication of plasmid R1 occurs in the presence of point mutations that disrupt the dnaA box of oriR.

scientific article published in May 1992

Effect of 3' terminal codon pairs with different frequency of occurrence on the expression of cat gene in Escherichia coli

scientific article

Efficient HIV-1 inhibition by a 16 nt-long RNA aptamer designed by combining in vitro selection and in silico optimisation strategies.

scientific article

Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter

scientific article published on 25 August 2008

End-to-end crosstalk within the hepatitis C virus genome mediates the conformational switch of the 3'X-tail region

scientific article published on 17 September 2013

Four ribose 2'-hydroxyl groups essential for catalytic function of the hairpin ribozyme

scientific article published on 01 September 1993

Functional Information Stored in the Conserved Structural RNA Domains of Flavivirus Genomes

scientific article (publication date: 2017)

Glucose conjugation of anti-HIV-1 oligonucleotides containing unmethylated CpG motifs reduces their immunostimulatory activity

scientific article published on 11 February 2015

HIV RNA dimerisation interference by antisense oligonucleotides targeted to the 5′ UTR structural elements ⬇️

scientific article published on July 20, 2012

HIV-1 TAR as anchoring site for optimized catalytic RNAs.

scientific article

Human interferon gamma: significance of the C-terminal flexible domain for its biological activity

scientific article published on 01 May 2003

In vitro and ex vivo selection procedures for identifying potentially therapeutic DNA and RNA molecules.

scientific article published on 28 June 2010

In vitro selection and evolution of RNA: applications for catalytic RNA, molecular recognition, and drug discovery.

scientific article published on January 1993

In vitro selection of active hairpin ribozymes by sequential RNA-catalyzed cleavage and ligation reactions.

scientific article published in January 1992

In vitro selection of hairpin ribozymes

scientific article published on 01 December 1996

Inhibition of HIV-1 replication and dimerization interference by dual inhibitory RNAs.

scientific article

Inhibition of HIV-1 replication by RNA targeted against the LTR region

scientific article

Inhibition of HIV-1 replication by RNA-based strategies.

scientific article

Inhibition of HIV-1 replication by an improved hairpin ribozyme that includes an RNA decoy

scientific article published on 20 April 2005

Inhibition of hepatitis C virus internal ribosome entry site-mediated translation by an RNA targeting the conserved IIIf domain.

scientific article

Insights into the specificity of RNA cleavage by the Escherichia coli MazF toxin

scientific article published in June 2004

Interfering with hepatitis C virus IRES activity using RNA molecules identified by a novel in vitro selection method.

scientific article

Ionic requirements for RNA binding, cleavage, and ligation by the hairpin ribozyme

scientific article published on 01 February 1993

Ligation of RNA molecules by the hairpin ribozyme

scientific article published on 01 January 1997

Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response

scientific article published on 09 January 2016

Non-Shine-Dalgarno initiators of translation selected from combinatorial DNA libraries

scientific article published in January 2003

Novel RNA polymerization reaction catalyzed by a group I ribozyme.

scientific article

Novel guanosine requirement for catalysis by the hairpin ribozyme

scientific article published in Nature

Novel system for analysis of group I 3' splice site reactions based on functional trans-interaction of the P1/P10 reaction helix with the ribozyme's catalytic core.

scientific article published on March 1995

Potential of the Other Genetic Information Coded by the Viral RNA Genomes as Antiviral Target

scientific article published on 13 March 2019

Preventing nondesired RNA-primed RNA extension catalyzed by T7 RNA polymerase.

scientific article

RNA aptamer‐mediated interference of HCV replication by targeting the CRE‐5BSL3.2 domain ⬇️

scientific article published on July 17, 2012

RNA self-cleavage activated by ultraviolet light-induced oxidation

scientific article published on 11 October 2011

RNase/anti-RNase activities of the bacterial parD toxin-antitoxin system

scientific article published on May 2005

Ribozymes: recent advances in the development of RNA tools ⬇️

scientific article published on April 1, 2003

Selection of targets and the most efficient hairpin ribozymes for inactivation of mRNAs using a self-cleaving RNA library

scientific article

Self-initiation of translation of mRNAs devoid of translational initiators in Escherichia coli.

scientific article published in January 2001

Specificity of the hairpin ribozyme. Sequence requirements surrounding the cleavage site

scientific article published on 01 October 1999

Structure and function analysis of the essential 3'X domain of hepatitis C virus

scientific article published on 06 November 2019

Substrate selection rules for the hairpin ribozyme determined by in vitro selection, mutation, and analysis of mismatched substrates

scientific article published in January 1993

Targets and tools: recent advances in the development of anti-HCV nucleic acids.

scientific article published on June 2006

The 5'-tail of antisense RNAII of pMV158 plays a critical role in binding to the target mRNA and in translation inhibition of repB.

scientific article published on 30 June 2015

The 5BSL3.2 Functional RNA Domain Connects Distant Regions in the Hepatitis C Virus Genome

scientific article published on 31 October 2017

The Capsicum L3 gene-mediated resistance against the tobamoviruses is elicited by the coat protein

scientific article published in June 1995

The HCV genome domains 5BSL3.1 and 5BSL3.3 act as managers of translation

scientific article published in Scientific Reports

The Role of the RNA-RNA Interactome in the Hepatitis C Virus Life Cycle

scientific article published on 21 February 2020

The antisense sequence of the HIV-1 TAR stem-loop structure covalently linked to the hairpin ribozyme enhances its catalytic activity against two artificial substrates

scientific article published on 01 February 1999

The chaperone-like activity of the hepatitis C virus IRES and CRE elements regulates genome dimerization

scientific article published on 24 February 2017

The cis-acting replication element of the Hepatitis C virus genome recruits host factors that influence viral replication and translation

scientific article published on 11 May 2016

The folding of the hepatitis C virus internal ribosome entry site depends on the 3'-end of the viral genome

scientific article published on 12 October 2012

The functional RNA domain 5BSL3.2 within the NS5B coding sequence influences hepatitis C virus IRES-mediated translation.

scientific article published on 20 May 2011

The kis and kid genes of the parD maintenance system of plasmid R1 form an operon that is autoregulated at the level of transcription by the co-ordinated action of the Kis and Kid proteins.

scientific article published in November 1991

Two Examples of RNA Aptamers with Antiviral Activity. Are Aptamers the Wished Antiviral Drugs?

scientific article published on 22 July 2020

Unmasking the information encoded as structural motifs of viral RNA genomes: a potential antiviral target.

scientific article published on 27 August 2013

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