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List of works by Kazuyuki Kitatani

Acceleration by ceramide of calcium-dependent translocation of phospholipase A2 from cytosol to membranes in platelets

scientific article published on 01 October 2000

Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid

scientific article

Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease

scientific article published on 27 August 2015

Ceramide Accelerates Dephosphorylation of Extracellular Signal-Regulated Kinase 1/2 to Decrease Prostaglandin D2 Production in RBL-2H3 Cells ⬇️

scientific article published on November 15, 2001

Ceramide enhances susceptibility of membrane phospholipids to phospholipase A2 through modification of lipid organization in platelet membranes

scientific article published on 01 December 1999

Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid

scientific article published on 14 September 2015

Ceramide nanoliposomes as a MLKL-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer

scientific article published on 27 October 2017

Ceramide synthase 2-C<sub>24:1</sub> -ceramide axis limits the metastatic potential of ovarian cancer cells

scientific article published on 01 February 2021

Ceramide-induced enhancement of secretory phospholipase A2 expression via generation of reactive oxygen species in tumor necrosis factor-alpha-stimulated mesangial cells

scientific article

Dietary glucosylceramides suppress tumor growth in a mouse xenograft model of head and neck squamous cell carcinoma by the inhibition of angiogenesis through an increase in ceramide.

scientific article published in August 2014

Fasudil improves the endothelial dysfunction in the aorta of spontaneously hypertensive rats.

scientific article

Identification and characterization of protein phosphatase 2C activation by ceramide ⬇️

scientific article published on May 21, 2012

Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer.

scientific article

Inhibitory effects of dietary glucosylceramides on squamous cell carcinoma of the head and neck in NOD/SCID mice.

scientific article published on 6 November 2010

Involvement of lipoxygenase pathway in docosapentaenoic acid-induced inhibition of platelet aggregation

scientific article published on 01 November 2000

Isofagomine in vivo effects in a neuronopathic Gaucher disease mouse.

scientific article

La-Related Protein 4 as a Suppressor for Motility of Ovarian Cancer Cells

scientific article published on 01 January 2019

Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.

scientific article published on 30 December 2005

Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis

scientific article

Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641.

scientific article published on 15 May 2007

Network Analysis of a Comprehensive Knowledge Repository Reveals a Dual Role for Ceramide in Alzheimer's Disease

scientific article published on 5 February 2016

Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers

scientific article published on 15 December 2017

P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment.

scientific article published on 07 August 2017

Pharmacological preconditioning of ATP-sensitive potassium channel openers on acute urinary retention-induced bladder dysfunction in the rat.

scientific article published on 28 February 2012

Phospholipase C and protein kinase C-β 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation

scientific article published on 20 October 2011

Potential of Tyrosine Kinase Receptor TIE-1 as Novel Therapeutic Target in High-PI3K-Expressing Ovarian Cancer

scientific article published on 26 June 2020

Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK.

scientific article published on 9 October 2006

Regulated secretion of acid sphingomyelinase: implications for selectivity of ceramide formation.

scientific article

Regulation of CC Ligand 5/RANTES by Acid Sphingomyelinase and Acid Ceramidase ⬇️

scientific article published on February 18, 2011

Regulation of Necroptosis by Phospholipids and Sphingolipids

scientific article published on 05 March 2020

Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway

scientific article published on 3 October 2012

Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway.

scientific article

Regulation of death and growth signals at the plasma membrane by sphingomyelin synthesis: implications for hematological malignancies

scientific article published on September 2011

Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies

scientific article published on 22 May 2015

Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism

scientific article

Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse

scientific article

Sphingolipids in Inflammation: From Bench to Bedside

scientific article published on 24 February 2016

Sphingomyelin Synthase 1-generated Sphingomyelin Plays an Important Role in Transferrin Trafficking and Cell Proliferation ⬇️

scientific article published on August 19, 2011

Stimulation by ceramide of phospholipase A2 activation through a mechanism related to the phospholipase C-initiated signaling pathway in rabbit platelets

scientific article published on 01 January 1999

Stimulation by de novo-synthesized ceramide of phospholipase A(2)-dependent cholesterol esterification promoted by the uptake of oxidized low-density lipoprotein in macrophages.

scientific article

Study profile of The Tohoku Medical Megabank Community-Based Cohort Study

scientific article published on 11 January 2020

The role of K ATP channels on ischemia-reperfusion injury in the rat testis

scientific article published on 28 March 2012

Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1: the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer

scientific article published on 9 November 2015

Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism.

scientific article published on 14 February 2005

Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer

scientific article published in Scientific Reports

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