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List of works by Fabien Pierrel

A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone

scientific article published on 24 January 2019

Biosynthesis and physiology of coenzyme Q in bacteria.

scientific article published on 28 January 2014

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity

scientific article

Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly.

scientific article

Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6

scientific article

Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency

scientific article

Coq6 is responsible for the C4-deamination reaction in coenzyme Q biosynthesis in Saccharomyces cerevisiae

scientific article published on 10 August 2015

Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster

scientific article published on October 2010

Demethylmenaquinol is a substrate of Escherichia coli nitrate reductase A (NarGHI) and forms a stable semiquinone intermediate at the NarGHI quinol oxidation site

scientific article

Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency.

scientific article published on 18 October 2013

Enzymatic modification of tRNAs: MiaB is an iron-sulfur protein

scientific article published on 6 March 2002

Evolution of Ubiquinone Biosynthesis: Multiple Proteobacterial Enzymes with Various Regioselectivities To Catalyze Three Contiguous Aromatic Hydroxylation Reactions.

scientific article published on July 2016

Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency.

scientific article published on 22 June 2017

Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis

scientific article

Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein

scientific article published on 11 March 2008

Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast.

scientific article

Metal Ion availability in mitochondria.

scientific article published on 16 January 2007

MiaB protein from Thermotoga maritima. Characterization of an extremely thermophilic tRNA-methylthiotransferase

scientific article published on 24 May 2003

MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA.

scientific article published on 30 August 2004

MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters.

scientific article published on 4 April 2007

Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase

scientific article

Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway

scientific article

Structural Reconstruction of <i>E. coli</i> Ubi Metabolon Using an AlphaFold2-Based Computational Framework

scientific article published in 2024

The Biosynthetic Pathway of Ubiquinone Contributes to Pathogenicity of Francisella novicida

scientific article published on 20 September 2021

The COQ2 genotype predicts the severity of coenzyme Q10 deficiency

scientific journal article

The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding.

scientific article

The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ.

scientific article published on 30 May 2017

The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10

scientific article

Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrins

scientific article published on 01 May 2014

Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage.

scientific article

Ubiquinone Biosynthesis over the Entire O2 Range: Characterization of a Conserved O2-Independent Pathway

scientific article published on 09 July 2019

Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6

scientific article published on 10 July 2019

Vitamin K2 cannot substitute Coenzyme Q as electron carrier in the mitochondrial respiratory chain of mammalian cells

scientific article published on 25 April 2019

ubiI,a New Gene inEscherichia coliCoenzyme Q Biosynthesis, Is Involved in Aerobic C5-hydroxylation

scientific article

ubiJ, a new gene required for aerobic growth and proliferation in macrophage, is involved in coenzyme Q biosynthesis in Escherichia coli and Salmonella enterica serovar Typhimurium

scientific article published on 18 October 2013