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List of works by Rainer Pepperkok

'Harvester': a fast meta search engine of human protein resources

scientific article (publication date: 12 August 2004)

A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways

scientific article

A correlative light and electron microscopy method based on laser micropatterning and etching

scientific article

A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2.

scientific article published on 22 December 2014

A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

scientific article

A microscope-based screening platform for large-scale functional protein analysis in intact cells

scientific article published in November 2003

A microtubule-independent role of p150glued in secretory cargo concentration at endoplasmic reticulum exit sites

scientific article

A new approach to manipulate the fate of single neural stem cells in tissue

scientific article

A novel laser nanosurgery approach supports de novo Golgi biogenesis in mammalian cells

scientific article

A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic

scientific article published on 15 November 2017

A role for kinesin-2 in COPI-dependent recycling between the ER and the Golgi complex

scientific article

Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells

Adaptive fluorescence microscopy by online feedback image analysis

scientific article

An Ordered Inheritance Strategy for the Golgi Apparatus: Visualization of Mitotic Disassembly Reveals a Role for the Mitotic Spindle ⬇️

scientific article published on May 18, 1998

An RNAi screen identifies KIF15 as a novel regulator of the endocytic trafficking of integrin

scientific article published on 21 March 2014

An RNAi screening platform to identify secretion machinery in mammalian cells

An antibody against secretogranin I (chromogranin B) is packaged into secretory granules

scientific article published in July 1989

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome

scientific article

Arrays of Transfected Mammalian Cells for High Content Screening Microscopy

article

At the cutting edge: applications and perspectives of laser nanosurgery in cell biology.

scientific article

Automated sanger DNA sequencing with one label in less than four lanes on gel

scientific article published on 01 January 1989

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging

scientific article

Automatic identification of subcellular phenotypes on human cell arrays

scientific article published on June 2004

Automatic microinjection system facilitates detection of growth inhibitory mRNA

scientific article

Being in the right location at the right time

scientific article

Beta-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo

scientific article published in July 1993

Biogenesis of tubular ER-to-Golgi transport intermediates

scientific article

Bioinformatic "Harvester": a search engine for genome-wide human, mouse, and rat protein resources

scientific article

Birth and life of tissue macrophages and their migration in embryogenesis and inflammation in medaka

scientific article published in January 2007

Breaking the COPI monopoly on Golgi recycling

scientific article

CDNAs for functional genomics and proteomics: the German Consortium

scientific article published on October 2003

CLEM<i>Site</i>, a software for automated phenotypic screens using light microscopy and FIB-SEM

scientific article published in 2022

CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum

scientific article

COPI vesicles accumulating in the presence of a GTP restricted arf1 mutant are depleted of anterograde and retrograde cargo

scientific article published on 01 January 2000

COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites

scientific journal article

COPs regulating membrane traffic

scientific article published on January 1995

Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells

scientific article

Casein kinase II is required for transition of G0/G1, early G1, and G1/S phases of the cell cycle.

scientific article published on March 1994

Cell growth stimulation by EGF: inhibition through antisense-oligodeoxynucleotides demonstrates important role of casein kinase II.

scientific article published on December 1991

Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

scientific article published on June 1990

Cell-to-cell communication: current views and future perspectives

scientific article published on 26 February 2013

Cellular Microbiochemistry

Cellular interactions and tubulin detyrosination in fibroblastic and epithelial cells

scientific article published on January 1991

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

scientific article published on January 2013

Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts

scientific article published on 22 September 2004

Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A

scientific article

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

scientific article (publication date: November 2002)

Coat proteins in intracellular membrane transport

scientific article published on August 1994

Confocal microscopy analysis of native, full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells

scientific article

Coupling of ER exit to microtubules through direct interaction of COPII with dynactin

scientific article

Cyclin A is required at two points in the human cell cycle

scientific article

DetecTiff: a novel image analysis routine for high-content screening microscopy

scientific article

Detection and quantification of protein-microtubules interactions using green fluorescent protein photoconversion

scientific article published in September 2006

Differential effects of a GTP-restricted mutant of Sar1p on segregation of cargo during export from the endoplasmic reticulum

scientific article published in July 2004

Differential requirements for ts-O45-G and procollagen biosynthetic transport

scientific article published on 5 June 2007

Dissociation of coatomer from membranes is required for brefeldin A-induced transfer of Golgi enzymes to the endoplasmic reticulum

scientific article published on April 1997

Dynamics of COPII vesicles and the Golgi apparatus in cultured Nicotiana tabacum BY-2 cells provides evidence for transient association of Golgi stacks with endoplasmic reticulum exit sites.

scientific article published in April 2005

Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita

scientific article

Early cell growth stimulation is inhibited by casein kinase II antisense oligodeoxynucleotides

scientific article published in October 1992

Erratum: Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer

scientific article published on 21 September 2015

Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum

scientific article published in November 1999

Factor VIII-eGFP fusion proteins with preserved functional activity for the analysis of the early secretory pathway of factor VIII.

scientific article published in November 2009

From ORFeome to biology: a functional genomics pipeline

scientific article

From experimental setup to bioinformatics: an RNAi screening platform to identify host factors involved in HIV-1 replication

scientific article

Functional genomics assays to study CFTR traffic and ENaC function

scientific article

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

scientific article

GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation

scientific article published on 23 January 2019

Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

scientific article

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway

Golgi depletion from living cells with laser nanosurgery

scientific article

High-content microscopy identifies new neurite outgrowth regulators

scientific article

High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic

scientific article

High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets.

scientific article

High-throughput RNAi screening by time-lapse imaging of live human cells

scientific article

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells

scientific article

High-throughput fluorescence microscopy for systems biology

scientific article published on 19 July 2006

High-throughput microscopy using live mammalian cells

scientific article published on July 2010

Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization

scientific article

Human Proteinpedia enables sharing of human protein data

scientific article

Id proteins control growth induction in mammalian cells

scientific article

Identification of cholesterol-regulating genes by targeted RNAi screening

scientific article

Illuminating the human genome.

scientific article

Illuminating the secretory pathway: when do we need vesicles?

scientific article

Imaging ER-to-Golgi transport: towards a systems view

scientific article published in November 2013

Imaging Platforms for Measurement of Membrane Trafficking

Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues

scientific article

Imaging of procollagen transport reveals COPI-dependent cargo sorting during ER-to-Golgi transport in mammalian cells

scientific article published in March 2002

Immunocytochemical localization of beta-COP to the ER-Golgi boundary and the TGN.

scientific article published on August 1995

Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells

article

Import of firefly luciferase into mammalian peroxisomes in vivo requires nucleoside triphosphates

scientific article published on March 1993

In migrating cells, the Golgi complex and the position of the centrosome depend on geometrical constraints of the substratum

scientific article

In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays

scientific article

In vivo detection of snRNP-rich organelles in the nuclei of mammalian cells ⬇️

scientific article published on July 1, 1991

In vivo selective cytoskeleton dynamics quantification in interphase cells induced by pulsed ultraviolet laser nanosurgery

scientific article published in December 2005

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.

scientific article published in March 2002

Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection

scientific article

Institutional core facilities: prerequisite for breakthroughs in the life sciences: Core facilities play an increasingly important role in biomedical research by providing scientists access to sophisticated technology and expertise

scientific article published on 13 July 2016

Integrating systems biology with clinical research

scientific article published on July 2008

Intracellular distribution of mammalian protein kinase A catalytic subunit altered by conserved Asn2 deamidation

scientific article

Intracellular movement of green fluorescent protein-tagged phosphatidylinositol 3-kinase in response to growth factor receptor signaling

scientific article published on August 1999

Involvement of the transmembrane protein p23 in biosynthetic protein transport

scientific article

KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p

scientific article published on November 1998

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system

scientific article

Laser nanosurgery in cell biology

scientific article published in June 2006

Live imaging of bidirectional traffic from the ERGIC.

scientific article published on 4 January 2005

Localizing the proteome

scientific article

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

scientific article

Maturation of the mammalian secretome

scientific article published in January 2007

Measuring secretory membrane traffic: a quantitative fluorescence microscopy approach

scientific article published on January 2008

Membrane-Permeant Phosphoinositide Derivatives as Modulators of Growth Factor Signaling and Neurite Outgrowth

Microinjection and Electroporation of Macromolecules into Live Cells

scholarly article published 1996

Micropilot: automation of fluorescence microscopy-based imaging for systems biology

scientific article

Microtubules are stabilized in confluent epithelial cells but not in fibroblasts

scientific article

Modification of the cytoplasmic domain affects the subcellular localization of Golgi glycosyl-transferases.

scientific article published on September 1996

Molecular characterization of two functional domains of CLIP-170 in vivo

scientific article (publication date: July 1994)

Molecular recognition of a single sphingolipid species by a protein's transmembrane domain

scientific article published on 9 January 2012

Movement of interphase Golgi apparatus in fused mammalian cells and its relationship to cytoskeletal elements and rearrangement of nuclei

scientific article published on 01 August 1990

Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.

scientific article

Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer

scientific article

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1

scientific article published on 11 November 2011

Observing proteins in their natural habitat: the living cell

scientific article

PIP₃ induces the recycling of receptor tyrosine kinases

scientific article published on 14 January 2014

Partitioning of the Golgi apparatus during mitosis in living HeLa cells

scientific article

Performance of an automated system for capillary microinjection into living cells

scientific article published on 01 August 1988

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

scientific article

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases

scientific article

Plasma membrane translocation of REDD1 governed by GPCRs contributes to mTORC1 activation

scientific article

Positive feedback between Golgi membranes, microtubules and ER exit sites directs de novo biogenesis of the Golgi.

scientific article

Production of siRNA- and cDNA-Transfected Cell Arrays on Noncoated Chambered Coverglass for High-Content Screening Microscopy in Living Cells

scientific article published on 01 January 2007

Profiling DNA damage response following mitotic perturbations

scientific article published on 15 December 2016

Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway

scientific article

Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery.

scientific article published on 12 March 2015

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

scientific article

Quantification of fluorescent spots in time series of 3D confocal microscopy images of endoplasmic reticulum exit sites based on the HMAX transform

Quantifying the influence of yellow fluorescent protein photoconversion on acceptor photobleaching-based fluorescence resonance energy transfer measurements

scientific article published in January 2012

Quantitative 3D-imaging for cell biology and ecology of environmental microbial eukaryotes

scientific article published on 31 October 2017

Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation.

scientific article

RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function

scientific article

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

scientific article

Rab18 and Rab43 have key roles in ER-Golgi trafficking

scientific article

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

scientific article

Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA polymerase and lac repressor

scientific article

Regulation of G1 progression by E2A and Id helix-loop-helix proteins

scientific article

Regulation of microtubule dynamics and nucleation during polarization in MDCK II cells.

scientific article

Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'

scientific article

Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts

scientific article

Reverse transfection on cell arrays for high content screening microscopy

scientific article published in January 2007

Reversible phosphorylation as a molecular switch to regulate plasma membrane targeting of acylated SH4 domain proteins.

scientific article

Secretory cargo regulates the turnover of COPII subunits at single ER exit sites

scientific article published in January 2006

Segregation of COPI-rich and anterograde-cargo-rich domains in endoplasmic-reticulum-to-Golgi transport complexes

scholarly article

Simultaneous detection of multiple green fluorescent proteins in live cells by fluorescence lifetime imaging microscopy

scientific article published on 01 March 1999

Single cell assay with an automated capillary microinjection system

scientific article

Single cell assay with an automated capillary microinjection system

scientific article published on 01 October 1988

Spectral imaging and its applications in live cell microscopy

scientific article

Spectral imaging and linear un-mixing enables improved FRET efficiency with a novel GFP2-YFP FRET pair

scientific article published on 01 November 2002

Sterols regulate ER-export dynamics of secretory cargo protein ts-O45-G.

scientific article published on 22 June 2006

System for quantitation of gene expression in single cells by computerized microimaging: application to c-fos expression after microinjection of anti-casein kinase II antibody.

scientific article published on February 1993

Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction

scientific article published on 3 February 2015

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing

article published in 2009

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

scientific article

Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy

scientific article

Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion

scientific article published on 10 March 2010

The 89,000-Mr murine cytomegalovirus immediate-early protein stimulates c-fos expression and cellular DNA synthesis

scientific article published on September 1988

The German cDNA network: cDNAs, functional genomics and proteomics

scientific article published on January 2003

The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum

article

The LIFEdb database in 2006

scientific article

The Spir actin organizers are involved in vesicle transport processes

scientific journal article

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

scientific article

The cytoplasmic domain of alphavirus E2 glycoprotein contains a short linear recognition signal required for viral budding ⬇️

scientific article published on September 1, 1991

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

scientific article

The intracellular mobility of a viral membrane glycoprotein measured by confocal microscope fluorescence recovery after photobleaching.

scientific article published on May 1994

The many ways to cross the plasma membrane.

scholarly article

The p24 family member p23 is required for early embryonic development

scientific journal article

The potential of high-content high-throughput microscopy in drug discovery

scientific article

The subcellular localization of the mammalian proteome comes a fraction closer

scientific article published on January 2006

Three distinct steps in transport of vesicular stomatitis virus glycoprotein from the ER to the cell surface in vivo with differential sensitivities to GTP gamma S.

scientific article published in July 1998

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

scientific article published on April 1992

Transfected cell microarrays: an efficient tool for high-throughput functional analysis

scientific article published on August 2007

Translocation biosensors to study signal-specific nucleo-cytoplasmic transport, protease activity and protein-protein interactions

scientific article published in July 2005

Visualization of ER-to-Golgi transport in living cells reveals a sequential mode of action for COPII and COPI

scientific journal article

Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates

scientific article

cDNA-derived molecular characteristics and antibodies to a new centrosome-associated and G2/M phase-prevalent protein

scientific journal article

ojoplano-mediated basal constriction is essential for optic cup morphogenesis.

scientific article published on July 2009

siRNA cell arrays for high-content screening microscopy

scientific article published in September 2004

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