List of works - Gregory D. Wiens

A BCWD-resistant line of rainbow trout exhibits higher abundance of IgT+ B cells and heavy chain tau transcripts compared to a susceptible line following challenge with Flavobacterium psychrophilum.

scientific article published on 4 May 2017

A single Ala139-to-Glu substitution in the Renibacterium salmoninarum virulence-associated protein p57 results in antigenic variation and is associated with enhanced p57 binding to chinook salmon leukocytes.

scientific article

Accurate genomic predictions for BCWD resistance in rainbow trout are achieved using low-density SNP panels: Evidence that long-range LD is a major contributing factor

scientific article published on 05 June 2018

Acute mortality, bacterial load, and pathology of select lines of adult rainbow trout challenged with Weissella sp. NC36.

scientific article published in December 2013

Analysis of the gut and gill microbiome of resistant and susceptible lines of rainbow trout (Oncorhynchus mykiss)

scientific article published on 01 December 2018

Aquacultured rainbow trout (Oncorhynchus mykiss) possess a large core intestinal microbiota that is resistant to variation in diet and rearing density.

scientific article published on 14 June 2013

Assessment of genetic correlation between bacterial cold water disease resistance and spleen index in a domesticated population of rainbow trout: identification of QTL on chromosome Omy19.

scientific article

B cell signatures of BCWD-resistant and susceptible lines of rainbow trout: a shift towards more EBF-expressing progenitors and fewer mature B cells in resistant animals

scientific article

Biochemical reference intervals and pathophysiological changes in Flavobacterium psychrophilum-resistant and -susceptible rainbow trout lines

scientific article published on October 2014

Challenges associated with heterologous expression of Flavobacterium psychrophilum proteins in Escherichia coli

scientific article published on 13 June 2008

Characterization of Toll-like receptor 3 gene in rainbow trout (Oncorhynchus mykiss).

scientific article published on August 2005

Complete Genome Sequence of Flavobacterium psychrophilum Strain CSF259-93, Used To Select Rainbow Trout for Increased Genetic Resistance against Bacterial Cold Water Disease.

scientific article

Dataset of proinflammatory cytokine and cytokine receptor gene expression in rainbow trout (Oncorhynchus mykiss) measured using a novel GeXP multiplex, RT-PCR assay

scientific article published on 12 February 2017

Deletion in HCDR3 rescues T15 antibody mutants from a secretion defect caused by mutations in HCDR2

scientific article published on 01 November 1996

Detection and Validation of QTL Affecting Bacterial Cold Water Disease Resistance in Rainbow Trout Using Restriction-Site Associated DNA Sequencing

scientific article published on 16 September 2015

Detection of QTL in rainbow trout affecting survival when challenged with Flavobacterium psychrophilum

scientific article published on 16 November 2013

Differential expression and evolution of three tandem, interleukin-1 receptor-like 1 genes in rainbow trout (Oncorhynchus mykiss)

article

Differential expression of long non-coding RNAs in three genetic lines of rainbow trout in response to infection with Flavobacterium psychrophilum.

scientific article published on 27 October 2016

Elevated temperature treatment as a novel method for decreasing p57 on the cell surface of Renibacterium salmoninarum

scientific article published on 01 April 1999

Evaluation of Genome-Enabled Selection for Bacterial Cold Water Disease Resistance Using Progeny Performance Data in Rainbow Trout: Insights on Genotyping Methods and Genomic Prediction Models

scientific article

Evaluation of a whole cell, p57- vaccine against Renibacterium salmoninarum

scientific article published on 01 April 1999

Evidence of major genes affecting resistance to bacterial cold water disease in rainbow trout using Bayesian methods of segregation analysis.

scientific article published on 10 September 2010

Flavobacterium branchiophilum and F. succinicans associated with bacterial gill disease in rainbow trout Oncorhynchus mykiss (Walbaum) in water recirculation aquaculture systems

scientific article published on 10 April 2014

Genetic Diversity of Flavobacterium psychrophilum Isolates from Three Oncorhynchus spp. in the United States, as Revealed by Multilocus Sequence Typing

scientific article published on 25 March 2016

Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor

scientific article published on 22 August 2008

Genomic Diversity and Evolution of the Fish Pathogen Flavobacterium psychrophilum

scientific article published on 7 February 2018

Genomic selection models double the accuracy of predicted breeding values for bacterial cold water disease resistance compared to a traditional pedigree-based model in rainbow trout aquaculture.

scientific article published on February 2017

Harmful somatic mutations: lessons from the dark side

scientific article published on 01 April 1998

Histopathologic Changes in Disease-Resistant-Line and Disease-Susceptible-Line Juvenile Rainbow Trout Experimentally Infected with Flavobacterium psychrophilum

scientific article published on September 2014

Identification of immunogenic proteins within distinct molecular mass fractions of Flavobacterium psychrophilum

scientific article published in November 2011

Identification of novel rainbow trout (Onchorynchus mykiss) chemokines, CXCd1 and CXCd2: mRNA expression after Yersinia ruckeri vaccination and challenge

scientific article published on 29 March 2006

Identification of potential vaccine target antigens by immunoproteomic analysis of a virulent and a non-virulent strain of the fish pathogen Flavobacterium psychrophilum.

scientific article published on February 2007

Identification of single nucleotide polymorphism markers associated with bacterial cold water disease resistance and spleen size in rainbow trout

scientific article

Identification, characterization and genetic mapping of TLR1 loci in rainbow trout (Oncorhynchus mykiss).

scientific article

Identification, characterization and genetic mapping of TLR7, TLR8a1 and TLR8a2 genes in rainbow trout (Oncorhynchus mykiss).

scientific article

Inefficient assembly and intracellular accumulation of antibodies with mutations in V(H) CDR2.

scientific article published in June 1998

Large-Scale Analysis of Flavobacterium psychrophilum Multilocus Sequence Typing Genotypes Recovered from North American Salmonids Indicates that both Newly Identified and Recurrent Clonal Complexes Are Associated with Disease

scientific article published on 06 March 2019

Mapping of neutralizing epitopes on Renibacterium salmoninarum p57 by use of transposon mutagenesis and synthetic peptides

scientific article

Microevolution of Renibacterium salmoninarum: evidence for intercontinental dissemination associated with fish movements

scientific article published on 31 October 2013

Mutation of a single conserved residue in VH complementarity-determining region 2 results in a severe Ig secretion defect.

scientific article published in August 2001

Origin and evolution of TNF and TNF receptor superfamilies

scientific article published on 19 April 2011

Potential mechanisms of attenuation for rifampicin-passaged strains of Flavobacterium psychrophilum

scientific article published on 16 September 2015

Proinflammatory cytokine and cytokine receptor gene expression kinetics following challenge with Flavobacterium psychrophilum in resistant and susceptible lines of rainbow trout (Oncorhynchus mykiss).

scientific article

Proteomic analysis of Flavobacterium psychrophilum cultured in vivo and in iron-limited media

scientific article published on 01 December 2009

Rainbow trout (Oncorhynchus mykiss) resistance to columnaris disease is heritable and favorably correlated with bacterial cold water disease resistance.

scientific article

Rainbow trout resistance to bacterial cold-water disease is moderately heritable and is not adversely correlated with growth.

scientific article published on 21 November 2008

Recovering antibody secretion using a hapten ligand as a chemical chaperone.

scientific article

Reduction of rainbow trout spleen size by splenectomy does not alter resistance against bacterial cold water disease

scientific article

Renibacterium salmoninarum p57 antigenic variation is restricted in geographic distribution and correlated with genomic markers

Replacements in the exposed loop of the T15 antibody VH CDR2 affect carrier recognition of PC-containing pathogens

scientific article published on 01 February 1999

Response to selection for bacterial cold water disease resistance in rainbow trout.

scientific article published on 12 February 2010

Serine proteinase of Renibacterium salmoninarum digests a major autologous extracellular and cell-surface protein

scientific article published on 01 October 1991

Similar Genetic Architecture with Shared and Unique Quantitative Trait Loci for Bacterial Cold Water Disease Resistance in Two Rainbow Trout Breeding Populations

scientific article published on 23 October 2017

Somatic mutation in VH complementarity-determining region 2 and framework region 2: differential effects on antigen binding and Ig secretion

scientific article published on 01 August 1997

Spleen size predicts resistance of rainbow trout to Flavobacterium psychrophilum challenge.

scientific article published on March 2008

Suggestive Association of Major Histocompatibility IB Genetic Markers with Resistance to Bacterial Cold Water Disease in Rainbow Trout (Oncorhynchus mykiss)

scientific article published on 15 February 2008

Temporal and pathogen-load dependent changes in rainbow trout (Oncorhynchus mykiss) immune response traits following challenge with biotype 2 Yersinia ruckeri.

scientific article published on 30 June 2010

The structural basis of repertoire shift in an immune response to phosphocholine

scientific article

The type IX secretion system is required for virulence of the fish pathogen Flavobacterium psychrophilum

scientific article published on 12 June 2020

Transfer of serum and cells from Yersinia ruckeri vaccinated doubled-haploid hot creek rainbow trout into outcross F1 progeny elucidates mechanisms of vaccine-induced protection.

scientific article published on 14 December 2013

Whole-body transcriptome of selectively bred, resistant-, control-, and susceptible-line rainbow trout following experimental challenge with Flavobacterium psychrophilum

scientific article

List of works by Gregory D. Wiens

A BCWD-resistant line of rainbow trout exhibits higher abundance of IgT+ B cells and heavy chain tau transcripts compared to a susceptible line following challenge with Flavobacterium psychrophilum.

A single Ala139-to-Glu substitution in the Renibacterium salmoninarum virulence-associated protein p57 results in antigenic variation and is associated with enhanced p57 binding to chinook salmon leukocytes.

Accurate genomic predictions for BCWD resistance in rainbow trout are achieved using low-density SNP panels: Evidence that long-range LD is a major contributing factor

Acute mortality, bacterial load, and pathology of select lines of adult rainbow trout challenged with Weissella sp. NC36.

Analysis of the gut and gill microbiome of resistant and susceptible lines of rainbow trout (Oncorhynchus mykiss)

Aquacultured rainbow trout (Oncorhynchus mykiss) possess a large core intestinal microbiota that is resistant to variation in diet and rearing density.

Assessment of genetic correlation between bacterial cold water disease resistance and spleen index in a domesticated population of rainbow trout: identification of QTL on chromosome Omy19.

B cell signatures of BCWD-resistant and susceptible lines of rainbow trout: a shift towards more EBF-expressing progenitors and fewer mature B cells in resistant animals

Biochemical reference intervals and pathophysiological changes in Flavobacterium psychrophilum-resistant and -susceptible rainbow trout lines

Challenges associated with heterologous expression of Flavobacterium psychrophilum proteins in Escherichia coli

Characterization of Toll-like receptor 3 gene in rainbow trout (Oncorhynchus mykiss).

Complete Genome Sequence of Flavobacterium psychrophilum Strain CSF259-93, Used To Select Rainbow Trout for Increased Genetic Resistance against Bacterial Cold Water Disease.

Dataset of proinflammatory cytokine and cytokine receptor gene expression in rainbow trout (Oncorhynchus mykiss) measured using a novel GeXP multiplex, RT-PCR assay

Deletion in HCDR3 rescues T15 antibody mutants from a secretion defect caused by mutations in HCDR2

Detection and Validation of QTL Affecting Bacterial Cold Water Disease Resistance in Rainbow Trout Using Restriction-Site Associated DNA Sequencing

Detection of QTL in rainbow trout affecting survival when challenged with Flavobacterium psychrophilum

Differential expression and evolution of three tandem, interleukin-1 receptor-like 1 genes in rainbow trout (Oncorhynchus mykiss)

Differential expression of long non-coding RNAs in three genetic lines of rainbow trout in response to infection with Flavobacterium psychrophilum.

Elevated temperature treatment as a novel method for decreasing p57 on the cell surface of Renibacterium salmoninarum

Evaluation of Genome-Enabled Selection for Bacterial Cold Water Disease Resistance Using Progeny Performance Data in Rainbow Trout: Insights on Genotyping Methods and Genomic Prediction Models

Evaluation of a whole cell, p57- vaccine against Renibacterium salmoninarum

Evidence of major genes affecting resistance to bacterial cold water disease in rainbow trout using Bayesian methods of segregation analysis.

Flavobacterium branchiophilum and F. succinicans associated with bacterial gill disease in rainbow trout Oncorhynchus mykiss (Walbaum) in water recirculation aquaculture systems

Genetic Diversity of Flavobacterium psychrophilum Isolates from Three Oncorhynchus spp. in the United States, as Revealed by Multilocus Sequence Typing

Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor

Genomic Diversity and Evolution of the Fish Pathogen Flavobacterium psychrophilum

Genomic selection models double the accuracy of predicted breeding values for bacterial cold water disease resistance compared to a traditional pedigree-based model in rainbow trout aquaculture.

Harmful somatic mutations: lessons from the dark side

Histopathologic Changes in Disease-Resistant-Line and Disease-Susceptible-Line Juvenile Rainbow Trout Experimentally Infected with Flavobacterium psychrophilum

Identification of immunogenic proteins within distinct molecular mass fractions of Flavobacterium psychrophilum

Identification of novel rainbow trout (Onchorynchus mykiss) chemokines, CXCd1 and CXCd2: mRNA expression after Yersinia ruckeri vaccination and challenge

Identification of potential vaccine target antigens by immunoproteomic analysis of a virulent and a non-virulent strain of the fish pathogen Flavobacterium psychrophilum.

Identification of single nucleotide polymorphism markers associated with bacterial cold water disease resistance and spleen size in rainbow trout

Identification, characterization and genetic mapping of TLR1 loci in rainbow trout (Oncorhynchus mykiss).

Identification, characterization and genetic mapping of TLR7, TLR8a1 and TLR8a2 genes in rainbow trout (Oncorhynchus mykiss).

Inefficient assembly and intracellular accumulation of antibodies with mutations in V(H) CDR2.

Large-Scale Analysis of Flavobacterium psychrophilum Multilocus Sequence Typing Genotypes Recovered from North American Salmonids Indicates that both Newly Identified and Recurrent Clonal Complexes Are Associated with Disease

Mapping of neutralizing epitopes on Renibacterium salmoninarum p57 by use of transposon mutagenesis and synthetic peptides

Microevolution of Renibacterium salmoninarum: evidence for intercontinental dissemination associated with fish movements

Mutation of a single conserved residue in VH complementarity-determining region 2 results in a severe Ig secretion defect.

Origin and evolution of TNF and TNF receptor superfamilies

Potential mechanisms of attenuation for rifampicin-passaged strains of Flavobacterium psychrophilum

Proinflammatory cytokine and cytokine receptor gene expression kinetics following challenge with Flavobacterium psychrophilum in resistant and susceptible lines of rainbow trout (Oncorhynchus mykiss).

Proteomic analysis of Flavobacterium psychrophilum cultured in vivo and in iron-limited media

Rainbow trout (Oncorhynchus mykiss) resistance to columnaris disease is heritable and favorably correlated with bacterial cold water disease resistance.

Rainbow trout resistance to bacterial cold-water disease is moderately heritable and is not adversely correlated with growth.

Recovering antibody secretion using a hapten ligand as a chemical chaperone.

Reduction of rainbow trout spleen size by splenectomy does not alter resistance against bacterial cold water disease

Renibacterium salmoninarum p57 antigenic variation is restricted in geographic distribution and correlated with genomic markers

Replacements in the exposed loop of the T15 antibody VH CDR2 affect carrier recognition of PC-containing pathogens

Response to selection for bacterial cold water disease resistance in rainbow trout.

Serine proteinase of Renibacterium salmoninarum digests a major autologous extracellular and cell-surface protein

Similar Genetic Architecture with Shared and Unique Quantitative Trait Loci for Bacterial Cold Water Disease Resistance in Two Rainbow Trout Breeding Populations

Somatic mutation in VH complementarity-determining region 2 and framework region 2: differential effects on antigen binding and Ig secretion

Spleen size predicts resistance of rainbow trout to Flavobacterium psychrophilum challenge.

Suggestive Association of Major Histocompatibility IB Genetic Markers with Resistance to Bacterial Cold Water Disease in Rainbow Trout (Oncorhynchus mykiss)

Temporal and pathogen-load dependent changes in rainbow trout (Oncorhynchus mykiss) immune response traits following challenge with biotype 2 Yersinia ruckeri.

The structural basis of repertoire shift in an immune response to phosphocholine

The type IX secretion system is required for virulence of the fish pathogen Flavobacterium psychrophilum

Transfer of serum and cells from Yersinia ruckeri vaccinated doubled-haploid hot creek rainbow trout into outcross F1 progeny elucidates mechanisms of vaccine-induced protection.

Whole-body transcriptome of selectively bred, resistant-, control-, and susceptible-line rainbow trout following experimental challenge with Flavobacterium psychrophilum