List of works - Niels Fischer

Atomic-resolution protein structure determination by cryo-EM

scientific article published on 21 October 2020

Conformational rearrangements upon start codon recognition in human 48S translation initiation complex

scientific article published on 30 April 2022

Energy barriers and driving forces in tRNA translocation through the ribosome

scientific article

Experimental identification of downhill protein folding.

scientific article

Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome

scientific article published on 15 June 2015

GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM.

scientific article published on 10 August 2015

GraFix: sample preparation for single-particle electron cryomicroscopy

scientific article

Mechanism of ribosome rescue by alternative ribosome-rescue factor B

scientific article published on 14 August 2020

ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space

scientific article (publication date: September 2015)

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

scientific article

Ribosome dynamics during decoding

scientific article published on March 2017

Spontaneous reverse movement of mRNA-bound tRNA through the ribosome.

scientific article published on 18 March 2007

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

scientific article published on July 2005

Structural mechanism of GTPase-powered ribosome-tRNA movement

scientific article published in 2021

Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM

scientific article

The pathway to GTPase activation of elongation factor SelB on the ribosome

scientific article published on 14 November 2016

Towards understanding selenocysteine incorporation into bacterial proteins

scientific article published on October 2007

List of works by Niels Fischer

Atomic-resolution protein structure determination by cryo-EM

Conformational rearrangements upon start codon recognition in human 48S translation initiation complex

Energy barriers and driving forces in tRNA translocation through the ribosome

Experimental identification of downhill protein folding.

Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome

GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM.

GraFix: sample preparation for single-particle electron cryomicroscopy

Mechanism of ribosome rescue by alternative ribosome-rescue factor B

ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

Ribosome dynamics during decoding

Spontaneous reverse movement of mRNA-bound tRNA through the ribosome.

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

Structural mechanism of GTPase-powered ribosome-tRNA movement

Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM

The pathway to GTPase activation of elongation factor SelB on the ribosome

Towards understanding selenocysteine incorporation into bacterial proteins