List of works by Paolo Bruzzi

5-Fluorouracil, epirubicin and cyclophosphamide versus epirubicin and paclitaxel in node-positive early breast cancer: a phase-III randomized GONO-MIG5 trial

scientific article published on 10 December 2015

A PET/CT approach to spinal cord metabolism in amyotrophic lateral sclerosis

scientific article published on 15 July 2016

A multicenter, randomized, double blind placebo-controlled trial of amoxicillin/clavulanate for the prophylaxis of fever and infection in neutropenic children with cancer

scientific article published on April 2003

A revised day +7 predictive score for transplant-related mortality: serum cholinesterase, total protein, blood urea nitrogen, gamma glutamyl transferase, donor type and cell dose.

scientific article published in July 2003

A risk score model predictive of the presence of additional disease in the axilla in early-breast cancer patients with one or two metastatic sentinel lymph nodes

article

Accelerated versus standard cyclophosphamide, epirubicin and 5-fluorouracil or cyclophosphamide, methotrexate and 5-fluorouracil: a randomized phase III trial in locally advanced breast cancer.

scientific article

Accuracy of sentinel lymph node biopsy after neo-adjuvant chemotherapy in patients with locally advanced breast cancer and clinically positive axillary nodes

scientific article published on 22 June 2011

Activity of first-line epirubicin and paclitaxel in metastatic breast cancer is independent of type of adjuvant therapy.

scientific article published on March 2004

Actual and preferred place of death of cancer patients. Results from the Italian survey of the dying of cancer (ISDOC).

scientific article published on May 2006

Added prognostic value of ischaemic threshold in radionuclide myocardial perfusion imaging: a common-sense integration of exercise tolerance and ischaemia severity.

scientific article published on 5 December 2014

Adjuvant chemotherapy in the treatment of colon cancer: randomized multicenter trial of the Italian National Intergroup of Adjuvant Chemotherapy in Colon Cancer (INTACC).

scientific article published in September 2003

Adjuvant mitotane treatment for adrenocortical carcinoma

scientific article

Adjuvant sequential methotrexate --> 5-fluorouracil vs 5-fluorouracil plus leucovorin in radically resected stage III and high-risk stage II colon cancer.

scientific article published on January 2005

Adult advanced chronic lymphocytic leukemia: computational analysis of whole-body CT documents a bone structure alteration.

scientific article published on 5 March 2014

An approach to the design and implementation of clinical trials of empirical antibiotic therapy in febrile and neutropenic cancer patients.

scientific article published on November 1995

Analysis and clinical relevance of human leukocyte antigen class I, heavy chain, and beta2-microglobulin downregulation in breast cancer.

scientific article published on 3 May 2009

Antioxidant supplement and long-term reduction of recurrent adenomas of the large bowel. A double-blind randomized trial

scientific article published on 13 October 2012

Association of breast cancer and polymorphisms of interleukin-10 and tumor necrosis factor-alpha genes

scientific article published on 01 October 2003

Attributable risks for oesophageal cancer in Northern Italy

article

Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life

scientific article published on 16 November 2004

BCR-ABL nuclear entrapment kills human CML cells: ex vivo study on 35 patients with the combination of imatinib mesylate and leptomycin B.

scientific article published on 25 October 2005

Bevacizumab plus fluorouracil: the value of being part of a developing story

scientific article published on 28 February 2005

Bladder cancer

scientific article published on 01 January 2002

Body Mass Index and Prognosis of Metastatic Breast Cancer Patients Receiving First-Line Chemotherapy

scientific article published on 14 August 2013

Bone marrow transplantation from unrelated donors: the impact of mismatches with substitutions at position 116 of the human leukocyte antigen class I heavy chain

article

Breast cancer incidence after hormonal treatments for infertility: systematic review and meta-analysis of population-based studies.

scientific article

CMV infection after transplant from cord blood compared to other alternative donors: the importance of donor-negative CMV serostatus

scientific article published on 27 May 2011

CTLA-4 +49A>G polymorphism of recipients of HLA-matched sibling allogeneic stem cell transplantation is associated with survival and relapse incidence.

scientific article published on 18 December 2009

Can we measure long-term treatment effects in multiple sclerosis?

scientific article published on 23 December 2014

Cancer of the nasopharynx

scientific article published on 01 February 2003

Clinical application of micronucleus test: a case-control study on the prediction of breast cancer risk/susceptibility

scientific article

Clinical performance of the (1,3)-β-D-glucan assay in early diagnosis of nosocomial Candida bloodstream infections

scientific article published on 12 October 2011

Clinical trials of multiple sclerosis monitored with enhanced MRI: new sample size calculations based on large data sets

scientific article

Cohort study of women affected by gross cystic disease. Correlation between cationic and hormonal composition of breast cyst fluid and the risk of breast cancer.

scientific article published in January 1990

Combined MRI lesions and relapses as a surrogate for disability in multiple sclerosis.

scientific article published on 5 October 2011

Comments on "evidence for acute neurotoxicity after chemotherapy"

scientific article published on 17 March 2011

Concomitant versus sequential administration of epirubicin and paclitaxel as first-line therapy in metastatic breast carcinoma: results for the Gruppo Oncologico Nord Ovest randomized trial.

scientific article

Concurrent vs sequential adjuvant chemotherapy and hormone therapy in breast cancer: a multicenter randomized phase III trial.

scientific article

Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours

Diagnosis and prognosis disclosure among cancer patients. Results from an Italian mortality follow-back survey

scientific article published on 21 March 2006

Diagnostic accuracy of computed tomographic colonography for the detection of advanced neoplasia in individuals at increased risk of colorectal cancer.

scientific article

Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA).

scientific article published on 03 March 2016

Disseminated neuroblastoma in children older than one year at diagnosis: comparable results with three consecutive high-dose protocols adopted by the Italian Co-Operative Group for Neuroblastoma

scientific article published in April 2003

Distal hyperplastic polyps do not predict proximal adenomas: results from a multicentric study of colorectal adenomas.

scientific article published in August 1997

Divergent determinants of 18F-NaF uptake and visible calcium deposition in large arteries: relationship with Framingham risk score.

scientific article published on 8 December 2013

Divergent targets of glycolysis and oxidative phosphorylation result in additive effects of metformin and starvation in colon and breast cancer

scientific article published on 22 January 2016

Do patients with rectosigmoid adenomas 5 mm or less in diameter need total colonoscopy?

scientific article published on 01 September 1999

Dose-dense FEC followed by dose-dense ixabepilone as neoadjuvant treatment for breast cancer patients: a feasibility study.

scientific article

Dose-dense adjuvant chemotherapy in early breast cancer patients: results from a randomized trial

scientific article

Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial

scientific article published on 7 May 2012

Duration of chemotherapy for metastatic breast cancer: a systematic review and meta-analysis of randomized clinical trials.

scientific article published on 04 April 2011

Effect of a palliative home care team on hospital admissions among patients with advanced cancer

scientific article published on 01 June 2003

Effectiveness of a project to prevent HIV vertical transmission in the Republic of Congo

scientific article published on 14 April 2013

Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial

scientific article published on 01 August 1995

Efficacy of normal saline versus heparinized saline solution for locking catheters of totally implantable long-term central vascular access devices in adult cancer patients

scientific article published in July 2012

Epirubicin plus low-dose trastuzumab in HER2 positive metastatic breast cancer

scientific article

Estrogen-Like Action of Tamoxifen on Vaginal Epithelium in Breast Cancer Patients ⬇️

scientific article published on 01 January 1981

Excellent outcome with reduced treatment for infants with disseminated neuroblastoma without MYCN gene amplification

scientific article

False-positive galactomannan platelia Aspergillus test results for patients receiving piperacillin-tazobactam.

scientific article published on 27 February 2004

Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial

scientific article published on 2 March 2015

Follow-up studies of patients with categorized breast cysts. Methodological issues

scientific article

Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients

scientific article published on 28 March 2016

Gonadotropin-releasing hormone analogues for the prevention of chemotherapy-induced premature ovarian failure in cancer women: systematic review and meta-analysis of randomized trials

scientific article

HER2 expression and efficacy of dose-dense anthracycline-containing adjuvant chemotherapy in breast cancer patients

scientific article published on July 2005

HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: a pooled analysis of randomized trials

scientific article published on 25 December 2007

High dose-intensity chemotherapy, with accelerated cyclophosphamide-doxorubicin-etoposide and granulocyte-macrophage colony stimulating factor, in the treatment of small cell lung cancer.

scientific article

High expression of 90K (Mac-2 BP) is associated with poor survival in node-negative breast cancer patients not receiving adjuvant systemic therapies

scientific article published on 01 January 2009

Identification and validation of a new set of five genes for prediction of risk in early breast cancer

scientific article published on 6 May 2013

Impact of body mass index (BMI) on the prognosis of high-risk early breast cancer (EBC) patients treated with adjuvant chemotherapy.

scientific article published on 26 July 2016

Incremental advance or seismic shift? The need to raise the bar of efficacy for drug approval

scientific article published on 13 October 2009

Influence of the spleen on the blood distribution of the leukocytes producing colony-stimulating activity (CSA) in man

scientific article published on 01 January 1981

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.

scientific article published in April 2009

Initial serum (1,3)-β-D-glucan as a predictor of mortality in proven candidaemia: findings from a retrospective study in two teaching hospitals in Italy and Brazil.

scientific article published on 9 June 2015

Intense immunosuppression followed by autologous stem cell transplantation in severe multiple sclerosis

scientific article published on 01 December 2005

Intermediate endpoints of primary systemic therapy in breast cancer patients

scientific article published on 01 January 2011

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

scientific article published on January 2011

Interobserver agreement in the histologic diagnosis of colorectal polyps. the experience of the multicenter adenoma colorectal study (SMAC).

scientific article published in March 2003

Intra-operative evaluation of the sentinel lymph node for T1-N0 breast-cancer patients: always or never? A risk/benefit and cost/benefit analysis

scientific article published on 02 July 2010

Is there a subset of patients with preoperatively diagnosed N2 non-small cell lung cancer who might benefit from surgical resection?

scientific article

Lack of benefit of maintenance paclitaxel in first-line chemotherapy in metastatic breast cancer.

scientific article published in August 2006

Lack of prognostic value of flow cytometric DNA content analysis in colorectal adenocarcinomas

scientific article published on 01 January 1994

Long-term prognosis following macroscopic complete response at second-look laparotomy in advanced ovarian cancer patients treated with platinum-based chemotherapy

scientific article published on 01 January 1995

MRI lesions as a surrogate for relapses in multiple sclerosis: a meta-analysis of randomised trials.

scientific article published on 03 June 2013

Magnetic resonance imaging as a potential surrogate for relapses in multiple sclerosis: a meta-analytic approach.

scientific article published in March 2009

Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy

scientific article published on 01 June 2000

Malignant melanoma

scientific article published on 01 July 2003

Metabolic treatment with L-carnitine in acute anterior ST segment elevation myocardial infarction. A randomized controlled trial

scientific article published on 09 May 2006

Mitomycin-ifosfamide-cisplatinum (MIP) vs MIP-interferon vs cisplatinum-carboplatin in metastatic non-small-cell lung cancer: a FONICAP randomised phase II study. Italian Lung Cancer Task Force.

scientific article

Modelling MRI enhancing lesion counts in multiple sclerosis using a negative binomial model: implications for clinical trials.

scientific article published in February 1999

Modelling new enhancing MRI lesion counts in multiple sclerosis

Modelling new enhancing MRI lesion counts in multiple sclerosis

scientific article published on 01 October 2001

Molecular epidemiology: new rules for new tools?

scientific article published on 14 July 2006

Mortality after bloodstream infections in allogeneic haematopoietic stem cell transplant (HSCT) recipients

scientific article published on 21 December 2011

Multicenter randomized phase III trial of epirubicin plus paclitaxel vs epirubicin followed by paclitaxel in metastatic breast cancer patients: focus on cardiac safety

scientific article published on July 2004

Multicentric, randomized phase III trial of two different adjuvant chemotherapy regimens plus three versus twelve months of trastuzumab in patients with HER2- positive breast cancer (Short-HER Trial; NCT00629278).

scientific article

No standard treatment is available for advanced pancreatic cancer.

scientific article published on June 1995

Non-drug industry funded research

scientific article published on 6 December 2007

Objective response to chemotherapy as a potential surrogate end point of survival in metastatic breast cancer patients

scientific article published on 13 June 2005

Ovarian suppression using luteinizing hormone-releasing hormone agonists during chemotherapy to preserve ovarian function and fertility of breast cancer patients: a meta-analysis of randomized studies.

scientific article published on 7 September 2015

Pathologic complete response as a potential surrogate for the clinical outcome in patients with breast cancer after neoadjuvant therapy: a meta-regression of 29 randomized prospective studies

scientific article

Pegfilgrastim administration after 24 or 72 or 96 h to allow dose-dense anthracycline- and taxane-based chemotherapy in breast cancer patients: a single-center experience within the GIM2 randomized phase III trial

scientific article published on 27 August 2015

Performance of BOADICEA and BRCAPRO genetic models and of empirical criteria based on cancer family history for predicting BRCA mutation carrier probabilities: a retrospective study in a sample of Italian cancer genetics clinics

scientific article published on 5 September 2013

Peripherally inserted central catheters (PICCs) in cancer patients under chemotherapy: A prospective study on the incidence of complications and overall failures.

scientific article

Phase II study of 5-fluorouracil plus leucovorin and interferon alpha 2b in advanced colorectal cancer.

scientific article published on January 1992

Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma

scientific article published on 20 April 2010

Phase II study of combined immunotherapy, chemotherapy, and radiotherapy in the postoperative treatment of advanced non-small-cell lung cancer

scientific article published on 01 January 2000

Phase III study in stage IV non-small-cell lung cancer patients treated with two courses of cisplatin/gemcitabine followed by a randomization to three additional courses of the same combination or gemcitabine alone

scientific article published on 09 March 2007

Planning of a screening programme for cervical cancer in Liguria and evaluation of the attitude of the female population towards cancer detection.

scientific article

Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole. ⬇️

scientific article

Population attributable risk for endometrial cancer in northern Italy

scientific article published on October 1989

Predictive and prognostic value of early response assessment using 18FDG-PET in advanced non-small cell lung cancer patients treated with erlotinib.

scientific article

Preoperative chemo-radiation therapy for localised retroperitoneal sarcoma: a phase I-II study from the Italian Sarcoma Group.

scientific article

Presurgical systemic treatment of nonmetastatic breast cancer: facts and open questions.

scientific article

Prevalence of the E1317Q variant of the APC gene in Italian patients with colorectal adenomas.

scientific article published in January 2002

Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.

scientific article published in May 2004

Primary chemotherapy in operable breast carcinoma comparing CMF (cyclophosphamide, methotrexate, 5-fluorouracil) with an anthracycline-containing regimen: short-term responses translated into long-term outcomes

scientific article published on 14 June 2005

Prognostic effect of DNA aneuploidy from bladder washings in superficial bladder cancer

scientific article published on 01 May 2007

Prognostic factors for survival in patients with advanced renal cell carcinoma undergoing nonmyeloablative allogeneic stem cell transplantation.

scientific article

Prognostic role of lymph-node level involvement in patients undergoing axillary dissection for breast cancer

scientific article published on 01 April 1998

QUOROM and the search for an updated 'clinical method' in the era of evidence-based medicine.

scientific article published in August 2000

Quality of life assessment and clinical decision-making*

scientific article published on 01 December 1997

Raising the bar for antineoplastic agents: how to choose threshold values for superiority trials in advanced solid tumors

scientific article published on 17 September 2014

Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments.

scientific article

Randomized Phase II Trial of Letrozole and Letrozole Plus Low-Dose Metronomic Oral Cyclophosphamide As Primary Systemic Treatment in Elderly Breast Cancer Patients

scientific article published on 01 August 2006

Randomized trial comparing cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) with rotational CMF, epirubicin and vincristine as primary chemotherapy in operable breast carcinoma

scientific article

Rare Cancers Europe (RCE) methodological recommendations for clinical studies in rare cancers: a European consensus position paper.

scientific article

Re: Acute myeloid leukemia or myelodysplastic syndrome following use of granulocyte colony-stimulating factors during breast cancer adjuvant chemotherapy.

scientific article published on 27 June 2007

Referral of Ovarian Cancer Patients for Genetic Counselling by Oncologists: Need for Improvement

scientific article

Refining sorafenib therapy: lessons from clinical practice.

scientific article published on 31 October 2014

Relationship between tumour shrinkage and reduction in Ki67 expression after primary chemotherapy in human breast cancer

scientific article

Reporting of subgroup analyses from clinical trials

scientific article published on 01 September 2012

Retrospective study of childhood ganglioneuroma.

scientific article published on April 2008

Role of carbonic anhydrase IX expression in prediction of the efficacy and outcome of primary epirubicin/tamoxifen therapy for breast cancer

scientific article published on 01 September 2006

Role of micronucleus test in predicting breast cancer susceptibility: a systematic review and meta-analysis

scientific article

START: a European state-of-the-art on-line instrument for clinical oncologists.

scientific article

Screening women at intermediate risk: harm or charm?

scientific article published on 01 September 2012

Self-perceived normality in defecation habits

scientific article

Sentinel Lymph Node Biopsy Versus Axillary Dissection in Node-Negative Early-Stage Breast Cancer: 15-Year Follow-Up Update of a Randomized Clinical Trial.

scientific article published on 14 March 2016

Sentinel node biopsy compared with complete axillary dissection for staging early breast cancer with clinically negative lymph nodes: results of randomized trial

scientific article published on 27 January 2009

Steroid biochemistry and categorization of breast cyst fluid: relation to breast cancer risk.

scientific article published on June 1994

Surrogate endpoints for EDSS worsening in multiple sclerosis: A meta-analytic approach

scientific article published on 23 June 2010

Survival of metastatic breast carcinoma patients over a 20-year period: a retrospective analysis based on individual patient data from six consecutive studies

scientific article

Syncope and risk of sudden death in hypertrophic cardiomyopathy.

scientific article published on 23 March 2009

TOSCA - first international registry to address knowledge gaps in the natural history and management of tuberous sclerosis complex.

scientific article

The FMR1 CGG repeat test is not a candidate prescreening tool for identifying women with a high probability of being carriers of BRCA mutations

scientific article published on 25 September 2013

The distribution of magnetic resonance imaging response to interferonβ–1b in multiple sclerosis

article

The distribution of the magnetic resonance imaging response to glatiramer acetate in multiple sclerosis.

scientific article published in August 2005

The general practitioner's approach to irritable bowel syndrome: from intention to practice

scientific article published on 21 October 2005

The general practitioner's management of patients with a new diagnosis of irritable bowel syndrome

scientific article published on 01 January 2006

The prognostic importance of left ventricular outflow obstruction in hypertrophic cardiomyopathy varies in relation to the severity of symptoms

scientific article published on 01 April 2005

The relationship between oral contraceptive use, cancer and vascular disease

scientific article

Therapy of endocrine disease: outcomes in patients with Cushing's disease undergoing transsphenoidal surgery: systematic review assessing criteria used to define remission and recurrence.

scientific article

Thymidine labelling index as prognostic factor in resected non-small cell lung cancer

scientific article published in January 1990

Time to progression in metastatic breast cancer patients treated with epirubicin is not improved by the addition of either cisplatin or lonidamine: final results of a phase III study with a factorial design

scientific article published in October 2002

Timing of adjuvant chemotherapy and tamoxifen in women with breast cancer: findings from two consecutive trials of Gruppo Oncologico Nord-Ovest-Mammella Intergruppo (GONO-MIG) Group

scientific article published on 17 October 2007

Transaortic Chordal Cutting: Mitral Valve Repair for Obstructive Hypertrophic Cardiomyopathy With Mild Septal Hypertrophy

scientific article published on 01 October 2015

Treatment of localised resectable neuroblastoma. Results of the LNESG1 study by the SIOP Europe Neuroblastoma Group.

scientific article published on 02 September 2008

Twelve-year experience with left atrial resection in the treatment of non-small cell lung cancer.

scientific article published in July 2004

Vatalanib in advanced colorectal cancer: two studies with identical results

scientific article published on 04 April 2011

Why are Cochrane hepato-biliary reviews undervalued by physicians as an aid for clinical decision-making?

scientific article published on 08 August 2009

Will Rogers phenomenon in multiple sclerosis.

scientific article

Wolfe's mammographic patterns in women with gross cystic disease of the breast

scientific article published on 01 July 1995

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