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List of works by William M. Miller

10th International Chemical and Biological Engineering Conference – CHEMPOR 2008 – Integrating Life Sciences & Engineering Special Section

A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH.

scientific article

A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH. Reprinted from Biotechnology and Bioengineering, Vol. 32, Pp 947-965 (1988).

scientific article published in March 2000

A rapid method for counting cell nuclei using a particle sizer/counter

article

A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis

scientific article

A uniform-shear rate microfluidic bioreactor for real-time study of proplatelet formation and rapidly-released platelets

scientific article published on 27 September 2017

Actin re-distribution in response to hydrogen peroxide in airway epithelial cells

scientific article published in April 2004

Administration of nicotinamide does not increase platelet levels in mice

scientific article

Ammonia inhibits neural cell adhesion molecule polysialylation in Chinese hamster ovary and small cell lung cancer cells.

scientific article

Beneficial effects of reduced oxygen tension and perfusion in long-term hematopoietic cultures

scientific article published on October 1992

Bicarbonate concentration and osmolality are key determinants in the inhibition of CHO cell polysialylation under elevated pCO(2) or pH.

scientific article published on October 1999

Bioreactor design for perfusion-based, highly-vascularized organ regeneration

scientific article published on February 2013

Bioreactor development for stem cell expansion and controlled differentiation

scientific article

Bone marrow niche-inspired, multiphase expansion of megakaryocytic progenitors with high polyploidization potential

scientific article

CHO cell responses to low oxygen: Regulation of oxygen consumption and sensitization to oxidative stress

article

Characterization of Hematopoietic Cell Expansion, Oxygen Uptake, and Glycolysis in a Controlled, Stirred-Tank Bioreactor System

scientific article published on 01 May 1998

Characterization of hybridoma cell responses to elevated pCO(2) and osmolality: intracellular pH, cell size, apoptosis, and metabolism

scientific article

Cholesterol Supplementation During Production Increases the Infectivity of Retroviral and Lentiviral Vectors Pseudotyped with the Vesicular Stomatitis Virus Glycoprotein (VSV-G)

scientific article published on May 2009

Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation

scientific article published on March 2007

Considerations for osmolality measurement under elevated pCO(2): comparison of vapor pressure and freezing point osmometry

scientific article published on January 2000

Continuous exposure of airway epithelial cells to hydrogen peroxide: protection by KGF.

scientific article published on July 2002

Culture materials affect ex vivo expansion of hematopoietic progenitor cells

scientific article

Determination of antibody content in live versus dead hybridoma cells: Analysis of antibody production in osmotically stressed cultures

article

Development of novel perfusion chamber to retain nonadherent cells and its use for comparison of human “mobilized” peripheral blood mononuclear cell cultures with and without irradiated bone marrow stroma

scientific article published on 01 June 1996

Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation

scientific article published in March 2002

Discrimination of fluorinated uridine metabolites in N-417 small cell lung cancer cell extracts via19F- and31P-NMR

scientific article published on 01 February 1994

Donor number estimation for oxygen- and nitrogen-containing solvents via proton NMR shift of chloroform

scholarly article by Susie Hahn published in February 1985

Dual-Purpose Bioreactors to Monitor Noninvasive Physical and Biochemical Markers of Kidney and Liver Scaffold Recellularization

scientific article

Dynamic model of ex vivo granulocytic kinetics to examine the effects of oxygen tension, pH, and interleukin-3.

scientific article published in September 2000

Dynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiation

scientific article

Editorial

Editorial

Effects of NHE1 expression level on CHO cell responses to environmental stress

scientific article published in March 2005

Effects of abrupt and gradual osmotic stress on antibody production and content in hybridoma cells that differ in production kinetics

scientific article published on March 1994

Effects of dissolved oxygen concentration on hybridoma growth and metabolism in continuous culture

scientific article published in September 1987

Effects of elevated pCO(2) and/or osmolality on the growth and recombinant tPA production of CHO cells

scientific article published in October 1996

Effects of osmoprotectant compounds on NCAM polysialylation under hyperosmotic stress and elevated pCO(2).

scientific article published in February 2002

Effects of supported lipid monolayer fluidity on the adhesion of hematopoietic progenitor cell lines to fibronectin-derived peptide ligands for alpha5beta1 and alpha4beta1 integrins

scientific article

Enabling Large-Scale Ex Vivo Production of Megakaryocytes from CD34+ Cells Using Gas-Permeable Surfaces

scientific article published on 08 March 2019

Energy sprawl or energy efficiency: climate policy impacts on natural habitat for the United States of America

scientific article

Energy, water and fish: biodiversity impacts of energy-sector water demand in the United States depend on efficiency and policy measures

scientific article (publication date: 2012)

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development

scientific article

Essential design considerations for the resazurin reduction assay to noninvasively quantify cell expansion within perfused extracellular matrix scaffolds

scientific article published on 16 February 2017

Ex vivo expansion of primitive hematopoietic cells for cellular therapies: An overview

Expansion of primitive human hematopoietic progenitors in a perfusion bioreactor system with IL-3, IL-6, and stem cell factor

scientific article published in March 1993

First-Order Toxicity Assays for Eye Irritation Using Cell Lines: Parameters That Affect in Vitro Evaluation

article

First-order toxicity assays for eye irritation using cell lines: parameters that affect in vitro evaluation

scientific article published on May 1995

Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis

scientific article published on 05 February 2008

Gene expression analysis illuminates the transcriptional programs underlying the functional activity of ex vivo-expanded granulocytes

scientific article published on 5 June 2007

Glycosylation of CHO-Derived Recombinant tPA Produced under Elevated pCO2

scientific article published on 01 January 1999

Hematopoietic cell culture therapies (Part I): Cell culture considerations.

scientific article published on September 1996

Hematopoietic cell culture therapies (Part II): Clinical aspects and applications.

scientific article

Hoxa10 null animals exhibit reduced platelet biogenesis

scientific article

Human megakaryocyte progenitors derived from hematopoietic stem cells of normal individuals are MHC class II-expressing professional APC that enhance Th17 and Th1/Th17 responses

scientific article

Hybridoma antibody content and production rate in continuous culture: Effect of dilution rate

article

Hyperosmotic stress and elevated pCO2 alter monoclonal antibody charge distribution and monosaccharide content

scientific article

Inverse-signal analysis with PCA

Lipopeptides incorporated into supported phospholipid monolayers have high specific activity at low incorporation levels

scientific article

Measurement of trans-epithelial electrical resistance in perfusion: Potential application for in vitro ocular toxicity testing

article

Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition

scientific article

Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions

scientific article published on July 2016

Mimicking stem cell niches to increase stem cell expansion

scientific article published on 08 September 2008

Model-based estimation of myeloid hematopoietic progenitor cells in ex vivo cultures for cell and gene therapies

scientific article published in January 2001

Modulation of glutathione level in CHO cells. Effects of oxygen concentration and prior exposure to hypoxia

scientific article published on October 1992

Mussel-inspired surface chemistry for multifunctional coatings

scientific article

Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes

scientific article published on November 2006

Optimization and critical evaluation of decellularization strategies to develop renal extracellular matrix scaffolds as biological templates for organ engineering and transplantation.

scientific article published on 17 November 2014

Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes

article

Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes

scientific article published in July 2001

Phosphate feeding improves high-cell-concentration NS0 myeloma culture performance for monoclonal antibody production

article

Physiologically significant effects of pH and oxygen tension on granulopoiesis

article

Polymer biocompatibility?effect on hybridoma growth and metabolism

Production of tPA in recombinant CHO cells under oxygen-limited conditions

article

Profiling deacetylase activities in cell lysates with peptide arrays and SAMDI mass spectrometry

scientific article

Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation

scientific article

Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles

scientific article published on October 2007

Real-time method for determining the colony-forming cell content of human hematopoietic cell cultures

article

Role of Nucleotide Sugar Pools in the Inhibition of NCAM Polysialylation by Ammonia

article

Role of tumor suppressor p53 in megakaryopoiesis and platelet function

scientific article published on 21 October 2011

SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation

scientific article (publication date: May 2016)

Selected amino acids protect hybridoma and CHO cells from elevated carbon dioxide and osmolality

scientific article

Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration

scientific article published on 19 November 2014

Small increases in pH enhance retroviral vector transduction efficiency of NIH-3T3 cells

scientific article published on January 2003

Stirred culture of peripheral and cord blood hematopoietic cells offers advantages over traditional static systems for clinically relevant applications

article

Surface presentation of bioactive ligands in a nonadhesive background using DOPA-tethered biotinylated poly(ethylene glycol).

scientific article published on 6 September 2007

Synergistic effect of hydrogen peroxide on polyploidization during the megakaryocytic differentiation of K562 leukemia cells by PMA.

scientific article

The Lactate Issue Revisited: Novel Feeding Protocols To Examine Inhibition of Cell Proliferation and Glucose Metabolism in Hematopoietic Cell Cultures

article

The transient responses of hybridoma cells to nutrient additions in continuous culture: II. Glutamine pulse and step changes

scientific article published in January 1989

Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production

scientific article published on 14 January 2013

Transduction efficiency of pantropic retroviral vectors is controlled by the envelope plasmid to vector plasmid ratio

scientific article

Transient responses of hybridoma cells to nutrient additions in continuous culture: I. Glucose pulse and step changes

scientific article

Transport in a Grooved Perfusion Flat-Bed Bioreactor for Cell Therapy Applications

scientific article published on 01 September 1998

Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis

scientific article published on 8 April 2008

n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines.

scientific article

pH is a potent modulator of erythroid differentiation

article

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