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List of works by Giuseppe Manco

A new phosphotriesterase from Sulfolobus acidocaldarius and its comparison with the homologue from Sulfolobus solfataricus.

scientific article published on 27 January 2007

A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: cloning, overexpression and properties

scientific article published on 21 May 2005

Activation of the Rhizobium leguminosarum glnII gene by NtrC is dependent on upstream DNA sequences

scientific article published on September 1992

Active site loop conformation regulates promiscuous activity in a lactonase from Geobacillus kaustophilus HTA426

scientific article

Alicyclobacillus acidocaldarius thermophilic esterase EST2's activity in milk and cheese models.

scientific article

An efficient thermostable organophosphate hydrolase and its application in pesticide decontamination.

scientific article

Analysis of thermal adaptation in the HSL enzyme family

scientific article

Biocatalytic membrane reactor development for organophosphates degradation

scientific article published on 17 November 2018

Biochemical and thermostability features of acetyl esterase Aes from Escherichia coli

scientific article published in January 2007

Boosted large-scale production and purification of a thermostable archaeal phosphotriesterase-like lactonase for organophosphate decontamination.

scientific article published on 11 January 2017

Carboxylesterases: a world with still words to say.

scientific article

Cell surface display of organophosphorus hydrolase for sensitive spectrophotometric detection of p-nitrophenol substituted organophosphates

scientific article published on 27 October 2013

Cloning, overexpression, and properties of a new thermophilic and thermostable esterase with sequence similarity to hormone-sensitive lipase subfamily from the archaeon Archaeoglobus fulgidus

scientific article published in January 2000

Comparison of the DING protein from the archaeon Sulfolobus solfataricus with human phosphate-binding protein and Pseudomonas fluorescence DING counterparts.

scientific article published on 11 January 2018

Comprehensive analysis of surface charged residues involved in thermal stability in Alicyclobacillus acidocaldarius esterase 2.

scientific article published on 3 October 2012

Crystallization and preliminary X-ray diffraction analysis of the hyperthermophilic Sulfolobus solfataricus phosphotriesterase.

scientific article

Crystallization and preliminary X-ray diffraction studies of Aes acetyl-esterase from Escherichia coli

scientific article

Crystallization and preliminary X-ray diffraction studies of the carboxylesterase EST2 from Alicyclobacillus acidocaldarius

scientific article published in July 1999

Denaturant-induced unfolding of the acetyl-esterase from Escherichia coli.

scientific article published in November 2004

Denaturing action of urea and guanidine hydrochloride towards two thermophilic esterases.

scientific article published in November 2002

Determination of Picomolar Concentrations of Paraoxon in Human Urine by Fluorescence-Based Enzymatic Assay

scientific article published on 07 November 2019

Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate

scientific article

Domain organization and DNA-induced conformational changes of an archaeal family B DNA polymerase.

scientific article

Domain organization and biochemical features of Sulfolobus solfataricus DNA polymerase

scientific article published in August 1998

EBP1 and DRBP76/NF90 binding proteins are included in the major histocompatibility complex class II RNA operon.

scientific article

Effect of Mutations on mRNA and Globin Stability: The Cases of Hb Bernalda/Groene Hart and Hb Southern Italy

scientific article published on 31 July 2020

Effect of trifluoroethanol on the conformational stability of a hyperthermophilic esterase: a CD study

scientific article published in June 2003

Evolution in the amidohydrolase superfamily: substrate-assisted gain of function in the E183K mutant of a phosphotriesterase-like metal-carboxylesterase

scientific article published on June 2009

Five-substrate cocktail as a sensor array for measuring enzyme activity fingerprints of lipases and esterases

scientific article published on 18 January 2011

Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius

scientific article

High yield production and purification of two recombinant thermostable phosphotriesterase-like lactonases from Sulfolobus acidocaldarius and Sulfolobus solfataricus useful as bioremediation tools and bioscavengers.

scientific article published on 20 March 2018

Highly Sensitive Detection of Chemically Modified Thio-Organophosphates by an Enzymatic Biosensing Device: An Automated Robotic Approach

scientific article published on 02 March 2020

Hyperthermophilic phosphotriesterases/lactonases for the environment and human health.

scientific article

Improving the promiscuous nerve agent hydrolase activity of a thermostable archaeal lactonase.

scientific article published on 27 July 2010

Inhibition of glutamine synthetase II expression by the product of the gstI gene

scientific article published on 01 July 2000

Innovative Biocatalysts as Tools to Detect and Inactivate Nerve Agents

scientific article published in Scientific Reports

Irreversible inhibition of the thermophilic esterase EST2 from Alicyclobacillus acidocaldarius.

scientific article published on 12 July 2008

Mn2+ modulates the kinetic properties of an archaeal member of the PLL family.

scientific article

Modification of the enantioselectivity of two homologous thermophilic carboxylesterases from Alicyclobacillus acidocaldarius and Archaeoglobus fulgidus by random mutagenesis and screening

scientific article published on 26 March 2002

Non-lipolytic and lipolytic sequence-related carboxylesterases: a comparative study of the structure-function relationships of rabbit liver esterase 1 and bovine pancreatic bile-salt-activated lipase

scientific article published on 22 July 2010

Oxalacetate decarboxylase and pyruvate carboxylase activities, and effect of sulfhydryl reagents in malic enzyme from Sulfolobus solfataricus

scientific article published in November 1988

Pyruvate dehydrogenase complex and lactate dehydrogenase as targets for therapy of acute liver failure

scientific article published on 23 March 2018

Redox stress proteins are involved in adaptation response of the hyperthermoacidophilic archaeon Sulfolobus solfataricus to nickel challenge.

scientific article published on 12 August 2007

Regulation of nitrogen metabolism is altered in a glnB mutant strain of Rhizobium leguminosarum.

scientific article

Residues at the active site of the esterase 2 from Alicyclobacillus acidocaldarius involved in substrate specificity and catalytic activity at high temperature

scientific article published on 10 July 2001

Role of the N terminus in enzyme activity, stability and specificity in thermophilic esterases belonging to the HSL family

scientific article published in January 2005

Role of the N-terminal region for the conformational stability of esterase 2 from Alicyclobacillus acidocaldarius.

scientific article published on 23 January 2007

Structural and Functional Characterization of New SsoPox Variant Points to the Dimer Interface as a Driver for the Increase in Promiscuous Paraoxonase Activity

scientific article published on 01 March 2020

Structural and kinetic overview of the carboxylesterase EST2 from alicyclobacillus acidocaldarius: a comparison with the other members of the HSL family.

scientific article published on January 2009

Structural basis for natural lactonase and promiscuous phosphotriesterase activities

scientific article

Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus.

scientific article published on 27 February 2009

Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases.

scientific article published on 17 November 2005

Temperature- and denaturant-induced unfolding of two thermophilic esterases.

scientific article published in January 2002

The conserved N-terminal helix of acylpeptide hydrolase from archaeon Aeropyrum pernix K1 is important for its hyperthermophilic activity

scientific article

The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family.

scientific article published in October 2004

The esterase from the thermophilic eubacterium Bacillus acidocaldarius: structural-functional relationship and comparison with the esterase from the hyperthermophilic archaeon Archaeoglobus fulgidus.

scientific article published in August 2000

The thermophilic esterase from Archaeoglobus fulgidus: structure and conformational dynamics at high temperature.

scientific article

Thermostable esterase 2 from Alicyclobacillus acidocaldarius as biosensor for the detection of organophosphate pesticides

scientific article published on 2 February 2011

Uridylylation of the PII protein in Rhizobium leguminosarum.

scientific article

Use of an inhibitor to identify members of the hormone-sensitive lipase family

scientific article published in November 2006

WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2

scientific article published on 07 May 2020

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