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List of works by Luisa M Villar

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

scientific article

A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands

scientific article published on 12 November 2014

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors

scientific article

A sensitive and reproducible method for the detection of oligoclonal IgM bands

scientific article published in December 2001

AAE and IgA myeloma

scientific article published on 01 October 2002

Accuracy of CSF and MRI criteria for dissemination in space in the diagnosis of multiple sclerosis

scientific article published on 19 September 2007

Adaptive natural killer cell response to cytomegalovirus and disability progression in multiple sclerosis.

scientific article published on 11 September 2015

An ultrasensitive method for the detection of oligoclonal IgG bands

scientific article published on 01 January 2004

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

scientific article published on 18 May 2016

Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions

scientific article published on 14 November 2019

Anti-SPAG16 antibodies in primary progressive multiple sclerosis are associated with an elevated progression index

scientific article published on 26 December 2015

Anti-myelin antibodies play an important role in the susceptibility to develop proteolipid protein-induced experimental autoimmune encephalomyelitis.

scientific article

Assessment of the reproducibility of oligoclonal IgM band detection for its application in daily clinical practice

scientific article

Autoantigen induced clonal expansion in immortalized B cells from the peripheral blood of multiple sclerosis patients

scientific article published on 5 June 2013

Axonal and oligodendrocyte-localized IgM and IgG deposits in MS lesions

scientific article published on 23 April 2012

Biomarkers in multiple sclerosis

scientific article published in April 2013

Blood lymphocyte subsets identify optimal responders to IFN-beta in MS.

scientific article

Brain atrophy and lesion load are related to CSF lipid-specific IgM oligoclonal bands in clinically isolated syndromes

scientific article published on 16 February 2011

CD106 and activated-CD29 are expressed on myelomatous bone marrow plasma cells and their downregulation is associated with tumour progression

scientific article published on 01 October 2002

CD29 expressed on plasma cells is activated by divalent cations and soluble CD106 contained in the bone marrow plasma: refractory activation is associated with enhanced proliferation and exit of clonal plasma cells to circulation in multiple myeloma

scientific article published on 02 December 2011

CSF oligoclonal band patterns reveal disease heterogeneity in multiple sclerosis

scientific article (publication date: 25 June 2009)

Cerebrospinal fluid chitinase 3-like 1 levels are associated with conversion to multiple sclerosis.

scientific article published on 17 March 2010

Cerebrospinal fluid immunological biomarkers associated with axonal damage in multiple sclerosis

scientific article published on 17 October 2014

Chitinase 3-like 1 is associated with the response to interferon-beta treatment in multiple sclerosis.

scientific article

Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

scientific article published on 13 February 2015

Circulating microparticles reflect treatment effects and clinical status in multiple sclerosis

scientific article published on 01 January 2014

Clinical usefulness of prognostic biomarkers in optic neuritis

scientific article published on 22 December 2017

Clinically isolated syndromes: a new oligoclonal band test accurately predicts conversion to MS.

scientific article published in February 2006

Cognitive impairment in early stages of multiple sclerosis is associated with high cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain

scientific article published on 22 June 2018

Comment on the article by Stauch et al. ‘Intrathecal IgM synthesis in paediatric MS is not a negative prognostic marker of disease progression: quantitative versus qualitative IgM analysis’

scientific article published on 24 August 2011

Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis

scientific article published on 21 May 2013

Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study.

scientific article

Correction to: Blood lymphocyte subsets identify optimal responders to IFN-beta in MS.

scientific article published on 24 November 2017

Current concepts in immunology

scientific article published in September 2008

DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands

scientific article

Decreased soluble IFN-β receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker.

scientific article published on 9 September 2016

Description of a Solid Phase Enzymoassay for the Detection of Reverse Transcriptase, DNA Polymerase, and Deoxyribonuclease

scientific article published on 01 January 1993

Description of an enzyme-linked immunosorbent assay for the detection of protein tyrosine kinase

scientific article published on 01 February 1991

Detection of soluble class i molecules (non hla-a or hla-b) in serum, spleen membranes and lymphocytes in culture

article

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

scientific article published on 17 June 2019

Early Differential Diagnosis of Multiple Sclerosis Using a New Oligoclonal Band Test

scientific article published on 01 April 2005

Exploring potential mechanisms of action of natalizumab in secondary progressive multiple sclerosis

scientific article

Guidelines for uniform reporting of body fluid biomarker studies in neurologic disorders

scientific article published on 22 August 2014

Gut dysbiosis and neuroimmune responses to brain infection with Theiler's murine encephalomyelitis virus.

scientific article published on 14 March 2017

HLA class II genotypic frequencies in atopic asthma

scientific article published on 01 August 2003

High frequency of co-infection by Epstein-Barr virus types 1 and 2 in patients with multiple sclerosis

scientific article published on 14 July 2011

High levels of cerebrospinal fluid free kappa chains predict conversion to multiple sclerosis

scientific article

How oral probiotics affect the severity of an experimental model of progressive multiple sclerosis? Bringing commensal bacteria into the neurodegenerative process

scientific article published on 01 November 2020

Identification of the major HHV-6 antigen recognized by cerebrospinal fluid IgG in multiple sclerosis.

scientific article

Immunoglobulin M oligoclonal bands: biomarker of targetable inflammation in primary progressive multiple sclerosis.

scientific article

Immunological markers of optimal response to natalizumab in multiple sclerosis.

scientific article

Immunological mechanisms that associate with oligoclonal IgM band synthesis in multiple sclerosis

scientific article published on 01 October 2010

Implication of soluble and membrane HLA class I and serum IL-10 in liver graft acceptance

scientific article published on 01 June 1999

Importance of age at diagnosis in multiple sclerosis

scientific article published on 01 March 2010

Increased Soluble Serum HLA Class I Antigens in Patients with Lymphoma

scientific article published on 01 December 1997

Increased beta 2-microglobulin in CSF of multiple sclerosis

scientific article published on September 1987

Increased peripheral blood CD5+ B cells predict earlier conversion to MS in high-risk clinically isolated syndromes

scientific article published on 24 March 2011

Influence of oligoclonal IgM specificity in multiple sclerosis disease course

scientific article published on 17 October 2007

Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis.

scientific article

Interleukin-6 dimers produced by endothelial cells inhibit apoptosis of B-chronic lymphocytic leukemia cells

scientific article published on 01 January 2001

Intrathecal IgM synthesis in neurologic diseases: Relationship with disability in MS

scientific article published on 01 March 2002

Intrathecal IgM synthesis is a prognostic factor in multiple sclerosis

scientific article published on 01 February 2003

Intrathecal IgM synthesis predicts the onset of new relapses and a worse disease course in MS.

scientific article

Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation

scientific article

Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS.

scientific article

Intrathecal synthesis of soluble class I antigens (sHLA) in patients with HIV infection and tuberculous meningitis

scientific article published in December 1990

Intrathecal synthesis of soluble class I antigens in multiple sclerosis

scientific article published in January 1992

Involved/uninvolved heavy/light chain index can predict progression in transplanted multiple myeloma patients.

scientific article

Involved/uninvolved immunoglobulin ratio identifies monoclonal gammopathy of undetermined significance patients at high risk of progression to multiple myeloma

scientific article published on 22 November 2013

Laboratory guidelines for the diagnosis and follow-up of patients with monoclonal gammopathies

scientific article

Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab

scientific article

Lipid-specific immunoglobulin M in CSF predicts adverse long-term outcome in multiple sclerosis.

scientific article

MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes.

scientific article published on 24 November 2015

Metabolomic signatures associated with disease severity in multiple sclerosis

scientific article published on 27 January 2017

Methimazole Has No Dose-Related Effect on the Serum Concentrations of Soluble Class I Major Histocompatibility Complex Antigens, Soluble Interleukin-2 Receptor, and β2-Microglobulin in Patients with Graves' Disease

scientific article published on 01 February 1996

Multimarker risk stratification approach at multiple sclerosis onset.

scientific article published on 31 May 2017

Multiple myeloma patients in long-term complete response after autologous stem cell transplantation express a particular immune signature with potential prognostic implication.

scientific article

Multiple sclerosis patients with anti-lipid oligoclonal IgM show early favourable response to immunomodulatory treatment

scientific article

Multiple sclerosis: Genetic variability affects CNS IgG production in MS.

scientific article published on 14 April 2015

Multiple sclerosis: Oligoclonal bands--a useful tool to avoid MS misdiagnosis

scientific article published on 16 April 2013

NLRP3 polymorphisms and response to interferon-beta in multiple sclerosis patients.

scientific article published in November 2017

Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles.

scientific article

Natural killer cell subsets in cerebrospinal fluid of patients with multiple sclerosis

scientific article published on May 2015

Neurofilament ELISA validation

scientific article published on 24 October 2009

Neurofilament light chain and oligoclonal bands are prognostic biomarkers in radiologically isolated syndrome

scientific article published on 14 February 2018

Neurofilament light chain level is a weak risk factor for the development of MS.

scientific article published on 12 August 2016

Neurofilament light chain levels in pregnant multiple sclerosis patients: a prospective cohort study

scientific article published on 09 May 2019

Novel cerebrospinal fluid and serum autoantibody targets for clinically isolated syndrome

scientific article published on 28 September 2012

Opsoclonus–myoclonus syndrome and limbic encephalitis associated with GABAB receptor antibodies in CSF

scientific article published on 26 April 2014

Optimal response to dimethyl fumarate associates in MS with a shift from an inflammatory to a tolerogenic blood cell profile

scientific article published in June 2017

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

scientific article

Progressive multifocal leukoencephalopathy, natalizumab, and multiple sclerosis

scientific article published in October 2005

Purification and properties of membrane and cytosolic phosphatidylinositol-specific phospholipases C from human spleen

scientific article published in Journal of Biological Chemistry

Quantification of soluble serum HLA Class I antigens in healthy volunteers and AIDS patients

scientific article published on 01 May 1988

Radiologically isolated syndrome: targeting miRNAs as prognostic biomarkers

scientific article published on 08 December 2020

Regulatory lymphocytes are key factors in MHC-independent resistance to EAE

scientific article

Response to interferon in multiple sclerosis is related to lipid-specific oligoclonal IgM bands

scientific article

Review of the novelties from the 31st ECTRIMS Congress, 2015, presented at the 8th Post-ECTRIMS meeting

scientific article

Review of the novelties presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (I).

scientific article published on September 2013

Review of the novelties presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (II).

scientific article

Review of the novelties presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (III).

scientific article published in October 2013

Soluble HLA class I antigen secretion by normal lymphocytes: relationship with cell activation and effect of interferon-gamma

scientific article published on 01 November 1990

Soluble class I antigen secretion by peripheral blood lymphocytes in multiple sclerosis

scientific article published on 01 January 1993

Soluble class I antigens in serum and CSF of patients with varicella-zoster virus meningitis

scientific article published on October 1989

Soluble class I histocompatibility antigens (s-HLA) and beta 2-microglobulin at delivery

scientific article

Spanish Immunology on the move

scientific article published in June 2015

Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis.

scientific article published in August 2014

Teriflunomide induces a tolerogenic bias in blood immune cells of MS patients

article

The expression of integrins on activated T-cells in multiple sclerosis. Effect of intravenous methylprednisolone treatment

scientific article published on 01 June 1998

The risk of relapse after a clinically isolated syndrome is related to the pattern of oligoclonal bands

scientific article published on 09 June 2010

Thioesterase and protein deacylase activities of porcine pancreatic phospholipase A2

scientific article published on 01 January 1996

Utility of oligoclonal IgG band detection for MS diagnosis in daily clinical practice.

scientific article published on 17 June 2011

Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis

scientific article

Value of oligoclonal band study in clinically isolated syndromes and multiple sclerosis

scientific article published on 01 September 2008

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