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List of works by R Charlotte Moffett

Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation

scientific article

Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice.

scientific article published on 20 June 2013

Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes.

scientific article published on 20 July 2012

Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice

scientific article published on 19 November 2015

Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice.

scientific article

Co-culture of clonal beta cells with GLP-1 and glucagon-secreting cell line impacts on beta cell insulin secretion, proliferation and susceptibility to cytotoxins.

scientific article published on 22 March 2016

Differential expression of glucagon-like peptide-2 (GLP-2) is involved in pancreatic islet cell adaptations to stress and beta-cell survival

scientific article

Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity.

scientific article published on 28 May 2015

Emerging role of GIP and related gut hormones in fertility and PCOS

scientific article published on 11 January 2020

Evaluation of the role of N-methyl-D-aspartate (NMDA) receptors in insulin secreting beta-cells

scientific article published on 10 December 2015

Functional GIP receptors play a major role in islet compensatory response to high fat feeding in mice

scientific article published on 14 February 2015

Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy

scientific article

Influence of neuropeptide Y and pancreatic polypeptide on islet function and beta-cell survival

scientific article published on 6 January 2017

Islet distribution of Peptide YY and its regulatory role in primary mouse islets and immortalised rodent and human beta-cell function and survival.

scientific article published on 24 July 2016

Locally produced xenin and the neurotensinergic system in pancreatic islet function and β-cell survival

scientific article

Molecular mechanisms mediating the beneficial metabolic effects of [Arg4]tigerinin-1R in mice with diet-induced obesity and insulin resistance.

scientific article published on 11 March 2016

Pharmacological characterization and antidiabetic activity of a long-acting glucagon-like peptide-1 analogue conjugated to an antithrombin III-binding pentasaccharide.

scientific article published on 30 April 2015

Positive effects of GLP-1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJ db/db mice with degenerative diabetes

scientific article published on 18 November 2014

Responses of GLP1-secreting L-cells to cytotoxicity resemble pancreatic β-cells but not α-cells

scientific article published on 19 December 2014

Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress

scientific article

Synthesis and Evaluation of a Series of Long-Acting Glucagon-Like Peptide-1 (GLP-1) Pentasaccharide Conjugates for the Treatment of Type 2 Diabetes.

scientific article published on 09 June 2015

[Erratum] Effects of glucose-dependent insulinotropic polypeptide receptor knockout and a high-fat diet on cognitive function and hippocampal gene expression in mice

scientific article published on 15 July 2015

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