List of works by Jeremy C. Mottram

17-AAG-Induced Activation of the Autophagic Pathway in <i>Leishmania</i> Is Associated with Parasite Death

scientific article published on 19 May 2021

3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism

scientific article published on 4 November 2002

A DiCre recombinase-based system for inducible expression in Leishmania major.

scientific article published on 16 June 2017

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

scientific article published on 27 September 2018

A cysteine proteinase cDNA from Trypanosoma brucei predicts an enzyme with an unusual C-terminal extension

scientific article published in December 1989

A developmentally regulated cysteine proteinase gene of Leishmania mexicana

scientific article

A family of trypanosome cdc2-related protein kinases

scientific article

A novel CDC2-related protein kinase from Leishmania mexicana, LmmCRK1, is post-translationally regulated during the life cycle.

scientific article

A potential role for ICP, a Leishmanial inhibitor of cysteine peptidases, in the interaction between host and parasite

scientific article

A transcriptional analysis of the Trypanosoma brucei hsp83 gene cluster

scientific article published in November 1989

ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major

scientific article

An essential role for the Leishmania major metacaspase in cell cycle progression.

scientific article

An essential signal peptide peptidase identified in an RNAi screen of serine peptidases of Trypanosoma brucei

scientific article

Analysis of the S(2) subsite specificities of the recombinant cysteine proteinases CPB of Leishmania mexicana, and cruzain of Trypanosoma cruzi, using fluorescent substrates containing non-natural basic amino acids

scientific article

Analysis of the roles of cysteine proteinases of Leishmania mexicana in the host-parasite interaction

scientific article published in October 2000

Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

scientific article published on 17 February 2020

Antigen presentation by Leishmania mexicana-infected macrophages: activation of helper T cells specific for amastigote cysteine proteinases requires intracellular killing of the parasites.

scientific article published on April 1995

Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets.

scientific article

Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129, and miR-210.

scientific article

Autophagy in protists.

scientific article published on February 2011

Biochemical and Immunological Characterization of Toxoplasma gondii Macrophage Migration Inhibitory Factor

scientific article

Bloodstream and metacyclic variant surface glycoprotein gene expression sites of Trypanosoma brucei gambiense

scientific article published in June 1990

Bloodstream form Trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes

scientific article published on 28 February 2006

Cathepsin B-like and cell death in the unicellular human pathogen Leishmania

scientific article published on 2 September 2010

Cathepsin B-like cysteine proteinase-deficient mutants of Leishmania mexicana.

scientific article published in September 1997

Cell death in Leishmania induced by stress and differentiation: programmed cell death or necrosis?

scientific article published in October 2002

Cell death in parasitic protozoa: regulated or incidental?

scientific article published on 03 December 2012

Characterisation of a gene for a cysteine protease from Theileria annulata

scientific article

Characterisation of theQMgene ofTrypanosoma brucei

scientific article published on 01 June 2002

Characterization of a multi-copy gene for a major stage-specific cysteine proteinase of Leishmania mexicana

scientific article published on October 1992

Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major

scientific article published on 04 February 2009

Chemical shift assignments of Leishmania mexicana ICP, a novel cysteine peptidase inhibitor

scientific article published on January 2006

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania

scientific article published on 28 October 2011

Clan CD cysteine peptidases of parasitic protozoa

scientific article

Combinatorial library of peptidotriazoles: identification of [1,2,3]-triazole inhibitors against a recombinant Leishmania mexicana cysteine protease

scientific article

Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi

scientific article

Comparative genomic analysis of three Leishmania species that cause diverse human disease

scientific article

Comparative structural analysis of the caspase family with other clan CD cysteine peptidases

scientific article

Comparative study of the ability of Leishmania mexicana promastigotes and amastigotes to alter macrophage signaling and functions.

scientific article published on 5 April 2010

Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in Leishmania mexicana cell cycle regulation

scientific article published on 16 March 2016

Conditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9-1-1 complex in the maintenance of the plastic genome of Leishmania

scientific article published on 01 December 2018

Conservation of cation-transporting ATPase genes in Leishmania

scientific article published in March 1991

Correction: Cytokinesis in Bloodstream Stage Trypanosoma brucei Requires a Family of Katanins and Spastin

scientific article

Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome

scientific article

Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor

scientific article

Crystal structure of a Trypanosoma brucei metacaspase

scientific article

Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections

scientific article published on 29 June 2023

Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression

scientific article published on 18 May 2016

Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine

scientific article published on 30 May 2006

Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana.

scientific article

Cysteine peptidases as virulence factors of Leishmania

scientific article published in August 2004

Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity

scientific article published in October 2003

Cytokinesis in bloodstream stage Trypanosoma brucei requires a family of katanins and spastin

scientific article

Cytokinesis in trypanosomatids

scientific article

Design and evaluation of Trypanosoma brucei metacaspase inhibitors.

scientific article

Differences in substrate specificities between cysteine protease CPB isoforms of Leishmania mexicana are mediated by a few amino acid changes

scientific article published on September 2004

Differentiation of Leishmania major is impaired by over-expression of pyroglutamyl peptidase I.

scientific article

Dipeptidyl alpha-fluorovinyl Michael acceptors: synthesis and activity against cysteine proteases

scientific article published on 23 October 2007

Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishmania major

scientific article published on 19 November 2012

Distinguishing functions of trypanosomatid protein kinases

scientific article published in 2022

Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

scientific article

Drug Discovery for Kinetoplastid Diseases: Future Directions

scientific article published on 13 December 2018

Drug candidate and target for leishmaniasis

scientific article published in Nature

Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation

scientific article

Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major.

scientific article published on 23 February 2006

Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8

scientific article

Essential roles for deubiquitination in Leishmania life cycle progression

scientific article published on 16 June 2020

Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis

scientific article

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

scientific article published on June 1996

Expression and characterization of a recombinant cysteine proteinase of Leishmania mexicana.

scientific article published on April 2000

Expression and substrate specificity of a recombinant cysteine proteinase B of Leishmania braziliensis.

scientific article

Expression of multiple CPB genes encoding cysteine proteases is required for Leishmania mexicana virulence in vivo

scientific article

Functional analysis of Leishmania cyclopropane fatty acid synthetase

scientific article

Functional conservation of a natural cysteine peptidase inhibitor in protozoan and bacterial pathogens

scientific article published in May 2003

Gene disruptions indicate an essential function for the LmmCRK1 cdc2-related kinase of Leishmania mexicana

scientific article published in November 1996

Generation of Leishmania mutants lacking antibiotic resistance genes using a versatile hit-and-run targeting strategy

scientific article

Genetically Validated Drug Targets in Leishmania; Current Knowledge and Future Prospects

scientific article published on 31 January 2018

Genome Dynamics during Environmental Adaptation Reveal Strain-Specific Differences in Gene Copy Number Variation, Karyotype Instability, and Telomeric Amplification

article

Genome sequence of Leishmania mexicana MNYC/BZ/62/M379 expressing Cas9 and T7 RNA polymerase

scientific article published in 2023

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

scientific article

Glycosome turnover in Leishmania major is mediated by autophagy

scientific article published in January 2014

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase

scientific article

High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a

scientific article published on 21 June 2012

Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase

scientific article (publication date: November 2013)

Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei

scientific article (publication date: 2013)

Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3.

scientific article published on 13 September 2011

Identification of lead compounds targeting the cathepsin B-like enzyme of Eimeria tenella

scientific article

Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana

scientific article

Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB

scientific article (publication date: 2013)

Imaging of the host/parasite interplay in cutaneous leishmaniasis

scientific article published on 23 May 2010

In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis

scientific article

Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major

scientific article published on 29 October 2008

Inhibition of Eimeria tenella CDK-related kinase 2: From target identification to lead compounds

scientific article

Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway

scientific article

Inhibitor of cysteine peptidase does not influence the development of Leishmania mexicana in Lutzomyia longipalpis.

scientific article published in May 2009

Inhibitor of serine peptidase 2 enhances Leishmania major survival in the skin through control of monocytes and monocyte-derived cells.

scientific article published on 2 November 2017

Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: chemical library screen and antileishmanial activity

scientific article

Intracellular Targets of Paullones. Identification following affinity purification on immobilized inhibitor

scientific article published on 18 April 2002

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

scientific article published in June 2000

Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes

scientific article

Isolation and sequence of four small nuclear U RNA genes of Trypanosoma brucei subsp. brucei: identification of the U2, U4, and U6 RNA analogs

scientific article published on March 1989

Isolation of Trypanosoma brucei CYC2 and CYC3 cyclin genes by rescue of a yeast G(1) cyclin mutant. Functional characterization of CYC2.

scientific article published in March 2000

Isolation of lmcpc, a gene encoding a Leishmania mexicana cathepsin-B-like cysteine proteinase

scientific article

Leishmania Cysteine Proteinases: Virulence Factors in Quest of a Function—Reply

scientific article published on 01 December 1998

Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

scientific article published on 27 October 2020

Leishmania inhibitor of serine peptidase 2 prevents TLR4 activation by neutrophil elastase promoting parasite survival in murine macrophages

scientific article published on 22 November 2010

Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity

article by Iveth J. González et al published February 2007 in International Journal for Parasitology

Leishmania mexicana cysteine proteinase-deficient mutants have attenuated virulence for mice and potentiate a Th1 response.

scientific article

Leishmania mexicana metacaspase is a negative regulator of amastigote proliferation in mammalian cells.

scientific article

Leishmania mexicana mutants lacking glycosylphosphatidylinositol (GPI):protein transamidase provide insights into the biosynthesis and functions of GPI-anchored proteins.

scientific article

Leishmania mexicana p12cks1, a homologue of fission yeast p13suc1, associates with a stage-regulated histone H1 kinase.

scientific article

Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression

scientific article published on 12 June 2011

Leishmania mexicana: Enzyme activities of amastigotes and promastigotes and their inhibition by antimonials and arsenicals

scientific article published on 01 April 1985

Leishmania mexicana: Subcellular distribution of enzymes in amastigotes and promastigotes

scientific article published on 01 June 1985

Leishmania mexicana: expression; characterization and activity assessment of E. coli-expressed recombinant CRK3.

scientific article published in October 2012

Mechanism of Trypanosoma brucei gambiense resistance to human serum

scientific article

Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing

scientific article published on 20 November 2007

Molecular cloning, characterization and overexpression of a novel cyclin from Leishmania mexicana

scientific article published on August 2010

Morphological events during the cell cycle of Leishmania major.

scientific article published on 16 September 2011

New Drugs for Human African Trypanosomiasis: A Twenty First Century Success Story

scientific article published on 19 February 2020

New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8

scientific article published on 09 July 2018

Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein

scientific article published on November 2002

Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana

scientific article published on February 1994

Oligopeptidase B deficient mutants of Leishmania major

scientific article

Overexpression of the natural inhibitor of cysteine peptidases in Leishmania mexicana leads to reduced virulence and a Th1 response

scientific article published on 11 May 2009

PFPI-like genes are expressed in Leishmania major but are pseudogenes in other Leishmania species

scientific article published on July 2006

PNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast

scientific article published on 3 March 2016

Parasite proteinases and amino acid metabolism: possibilities for chemotherapeutic exploitation.

scientific article published on January 1997

Pathogenicity and protective immunogenicity of cysteine proteinase-deficient mutants of Leishmania mexicana in non-murine models

scientific article published on 10 October 2005

Plasmodium cdc2-related kinases: Do they regulate stage differentiation?

scientific article published on 01 January 1997

Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation.

scientific article published on 29 August 2013

Processing and trafficking of Leishmania mexicana GP63. Analysis using GP18 mutants deficient in glycosylphosphatidylinositol protein anchoring

scientific article published on 23 May 2002

Processing and trafficking of cysteine proteases in Leishmania mexicana

scientific article published on 01 November 2000

Protease trafficking in two primitive eukaryotes is mediated by a prodomain protein motif

scientific article published on June 1999

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

scientific article

Protein kinases as drug targets in parasitic protozoa

scientific article

Protein kinases as drug targets in trypanosomes and Leishmania

scientific article

Protein turnover and differentiation in Leishmania.

scientific article

Purification of particulate malate dehydrogenase and phosphoenolpyruvate carboxykinase from Leishmania mexicana mexicana

scientific article published on 01 March 1985

Purification, characterization, and crystallization of Trypanosoma metacaspases

scientific article published in January 2014

RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse

scientific article published on 21 July 2017

Recent advances in Leishmania reverse genetics: Manipulating a manipulative parasite

scientific article

Recent advances in identifying and validating drug targets in trypanosomes and leishmanias.

scientific article

Recombinant Leishmania mexicana CRK3:CYCA has protein kinase activity in the absence of phosphorylation on the T-loop residue Thr178.

scientific article

Reduction of Tubulin Expression in Angomonas deanei by RNAi Modifies the Ultrastructure of the Trypanosomatid Protozoan and Impairs Division of Its Endosymbiotic Bacterium

scientific article

Regulators of Trypanosoma brucei cell cycle progression and differentiation identified using a kinome-wide RNAi screen

scientific article (publication date: 2014)

Role for the flagellum attachment zone in Leishmania anterior cell tip morphogenesis

scientific article published on 22 October 2020

Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFα and IFNβ.

scientific article

Role of the Trypanosoma brucei natural cysteine peptidase inhibitor ICP in differentiation and virulence

scientific article published on 17 October 2007

Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions.

scientific article

Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen

scientific article

Sequence of a tRNA gene cluster inTrypanosoma brucei ⬇️

scientific article published on July 25, 1991

Solid-phase library synthesis, screening, and selection of tight-binding reduced peptide bond inhibitors of a recombinant Leishmania mexicana cysteine protease B.

scientific article

Soluble GPI8 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins.

scientific article published on November 2000

Specific negative charges in cysteine protease isoforms of Leishmaniamexicana are highly influential on the substrate binding and hydrolysis.

scientific article

Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases

scientific article published on 9 August 2007

Stable transformation of trypanosomatids through targeted chromosomal integration of the selectable marker gene encoding blasticidin S deaminase.

scientific article

Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin

scientific article published on 7 April 2003

Structures of Leishmania major orthologues of macrophage migration inhibitory factor

scientific article

Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5.

scientific article

Subcellular localisation of purine-metabolising enzymes in Leishmania mexicana mexicana.

scientific article

Substrate specificity and the effect of calcium on Trypanosoma brucei metacaspase 2.

scientific article published on 16 April 2013

Substrate specificity of recombinant cysteine proteinase, CPB, of Leishmania mexicana

scientific article published in August 2001

Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

scientific article published on 23 February 2021

TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection

scientific article published on 27 December 2018

Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes.

scientific article

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

scientific article published on 13 July 2020

The AP3 adaptor is involved in the transport of membrane proteins to acidocalcisomes of Leishmania.

scientific article published on 5 February 2008

The ATR kinase of Trypanosoma brucei links DNA damage signalling and monoallelic control of surface antigen gene expression during antigenic variation

article

The CRK3 protein kinase is essential for cell cycle progression of Leishmania mexicana.

scientific article published in April 2001

The Comparative Genomics and Phylogenomics of Leishmania amazonensis Parasite.

scientific article published on 23 September 2014

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

scientific article

The Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses

scientific article

The SNARE protein family of Leishmania major

scientific article

The Trypanosoma brucei cyclin, CYC2, is required for cell cycle progression through G1 phase and for maintenance of procyclic form cell morphology

scientific article published on 22 March 2004

The amitochondriate eukaryote Trichomonas vaginalis contains a divergent thioredoxin-linked peroxiredoxin antioxidant system.

scientific article published on 20 November 2003

The cell cycle of parasitic protozoa: potential for chemotherapeutic exploitation.

scientific article published on January 2003

The crk3 gene of Leishmania mexicana encodes a stage-regulated cdc2-related histone H1 kinase that associates with p12.

scientific article published in April 1998

The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase. A three-domain architecture with a serine protease-like triad at the active site

scientific article

The genome of the kinetoplastid parasite, Leishmania major

scientific article

The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host

scientific article published on 18 June 2021

The multiple cpb cysteine proteinase genes of Leishmania mexicana encode isoenzymes that differ in their stage regulation and substrate preferences

scientific article published in May 1997

The primitive protozoon Trichomonas vaginalis contains two methionine gamma-lyase genes that encode members of the gamma-family of pyridoxal 5'-phosphate-dependent enzymes

scientific article published in March 1998

The role of conserved residues of chagasin in the inhibition of cysteine peptidases

scientific article published on 15 January 2008

The stage-regulated expression of Leishmania mexicana CPB cysteine proteases is mediated by an intercistronic sequence element

scientific article

The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants

scientific article

The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors

scientific article published on 28 December 2005

The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei

scientific article

Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis

scientific article published on 01 January 2018

Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis

scientific article published on 10 December 2019

Tracking autophagy during proliferation and differentiation of Trypanosoma brucei

scientific article published on 06 January 2014

Trichomonas vaginalis pathobiology new insights from the genome sequence.

scientific article published on January 2011

Trypanosoma brucei CYC1 does not have characteristics of a mitotic cyclin

scientific article published in November 2000

Trypanosoma brucei MOB1 is required for accurate and efficient cytokinesis but not for exit from mitosis

scientific article

Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis

scientific article

Trypanosoma brucei brucei: endocytic recycling is important for mouse infectivity

scientific article published on 20 January 2011

Trypanosoma brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes

scientific article published on 26 July 2013

Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor

scientific article published on 23 September 2011

Vaccination with a preparation based on recombinant cysteine peptidases and canine IL-12 does not protect dogs from infection with Leishmania infantum

scientific article published on 4 January 2006

Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

scientific article

cdc2-related protein kinases and cell cycle control in trypanosomatids.

scientific article published in July 1994

flagellum attachment zone is critical for flagellar pocket shape, development in the sand fly, and pathogenicity in the host

article

tRNAs of Trypanosoma brucei. Unusual gene organization and mitochondrial importation ⬇️

scientific article published on September 25, 1991

α-ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB.

scientific article published on October 2010

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