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List of works by Jorge F. Gaspar

(1-3)-beta-D-glucan in association with lactate dehydrogenase as biomarkers of Pneumocystis pneumonia (PcP) in HIV-infected patients.

scientific article published on 3 February 2014

8,15-epoxylabdane and norlabdane diterpenoids from Eragrostis viscosa.

scientific article published on 26 February 2010

ACMA (9-amino-6-chloro-2-methoxy acridine) forms three complexes in the presence of DNA.

scientific article

Aromatic DNA adduct levels in coke oven workers: correlation with polymorphisms in genes GSTP1, GSTM1, GSTT1 and CYP1A1.

scientific article published in May 2002

Association of Polymorphisms in ERCC2 Gene with Non-Familial Thyroid Cancer Risk

article

Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study.

scientific article published on 25 September 2009

Association of polymorphisms in genes of the homologous recombination DNA repair pathway and thyroid cancer risk

scientific article published in October 2009

Biological assays and noncovalent interactions of pyridine-2-carbaldehyde thiosemicarbazonecopper(II) drugs with [poly(dA-dT)](2), [poly(dG-dC)] (2), and calf thymus DNA.

scientific article published on 20 January 2010

Breast cancer risk and common single nucleotide polymorphisms in homologous recombination DNA repair pathway genes XRCC2, XRCC3, NBS1 and RAD51.

scientific article

Chemical features of flavonols affecting their genotoxicity. Potential implications in their use as therapeutical agents.

scientific article

Clinical relevance of multiple single-nucleotide polymorphisms in Pneumocystis jirovecii Pneumonia: development of a multiplex PCR-single-base-extension methodology.

scientific article

Combined effects of glutathione S-transferase polymorphisms and thyroid cancer risk

scientific article published in May 2004

Cytogenetic and DNA damage on workers exposed to styrene.

scientific article published on 20 August 2010

Cytogenetic and molecular biomonitoring of a Portuguese population exposed to pesticides

article

Cytogenetic damage induced by acrylamide and glycidamide in mammalian cells: correlation with specific glycidamide-DNA adducts

scientific article published on 6 November 2006

Cytotoxicity and chromosomal aberrations induced by acrylamide in V79 cells: role of glutathione modulators

scientific article published on 22 April 2009

DNA damage and susceptibility assessment in industrial workers exposed to styrene.

scientific article published in January 2012

DNA polymorphisms as modulators of genotoxicity and cancer.

scientific article

Detection of Pneumocystis jirovecii dihydropteroate synthase polymorphisms in patients with Pneumocystis pneumonia.

scientific article published on January 2005

Development of pyridine-containing macrocyclic copper(II) complexes: potential role in the redox modulation of oxaliplatin toxicity in human breast cells

scientific article published on 20 June 2012

Dihydropteroate synthase (DHPS) genotyping by PCR-RFLP analysis of Pneumocystis jirovecii repeated isolates from HIV-infected patients: a preliminary study

scientific article published on January 2003

GSTM1, GSTT1, and GSTP1 genotypes and the genotoxicity of hydroquinone in human lymphocytes

scientific article

Genetic Polymorphisms in Detoxification and DNA Repair Genes and Susceptibility to Glycidamide-Induced DNA Damage

article

Genetic characterization of the UCS and Kex1 loci of Pneumocystis jirovecii.

scientific article published on 21 August 2008

Genotoxic damage in hospital workers exposed to ionizing radiation and metabolic gene polymorphisms.

scientific article

Genotoxic damage in pathology anatomy laboratory workers exposed to formaldehyde

scientific article published on 31 July 2008

Genotoxic effect of exposure to metal(loid)s. A molecular epidemiology survey of populations living and working in Panasqueira mine area, Portugal

scientific article published on 13 September 2013

Genotoxic effects of doxorubicin in cultured human lymphocytes with different glutathione S-transferase genotypes

scientific article published on 26 May 2011

Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.

scientific article published on 30 March 2012

Genotoxicity of instant coffee and of some phenolic compounds present in coffee upon nitrosation.

scientific article published in January 2000

Genotoxicity of instant coffee: possible involvement of phenolic compounds

scientific article published in June 1999

Genotoxicity of nitrosated red wine and of the nitrosatable phenolic compounds present in wine: tyramine, quercetin and malvidine-3-glucoside.

scientific article

Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde

scientific article published on 22 February 2015

Induction of chromosomal aberrations by phenolic compounds: possible role of reactive oxygen species.

scientific article published in September 2003

Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide

scientific article published on 31 January 2013

Macrocyclic copper(II) complexes: superoxide scavenging activity, structural studies and cytotoxicity evaluation.

scientific article published on 11 February 2007

Mechanisms of induction of chromosomal aberrations by hydroquinone in V79 cells.

scientific article published in November 2003

Mechanisms of myricetin mutagenicity in V79 cells: involvement of radicalar species

scientific article published on 01 January 1996

Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells

scientific article published on November 2013

Menopausal age and XRCC1 gene polymorphisms: role in breast cancer risk

scientific article published on 01 January 2007

Metabolism of galangin by rat cytochromes P450: relevance to the genotoxicity of galangin ⬇️

scientific article published on October 24, 1997

Mutagenic activity of glycine upon nitrosation in the presence of chloride and human gastric juice: a possible role in gastric carcinogenesis

scientific article published in January 1996

Mutagenicity of kaempferol in V79 cells: The role of cytochromes P450 ⬇️

scientific article published on January 1, 1996

Newneo-Clerodanes fromTinnea antiscorbuticaWelv

Normal red blood cells partially decrease diepoxybutane-induced chromosome breakage in cultured lymphocytes from Fanconi anaemia patients

scientific article published on December 2010

Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1.

scientific article published in February 2004

Oxidative injury in V79 Chinese hamster cells: protective role of the superoxide dismutase mimetic MnTM-4-PyP.

scientific article

Polymorphisms in base excision repair genes and thyroid cancer risk.

scientific article

Population structure of Pneumocystis jirovecii isolated from immunodeficiency virus-positive patients

scientific article published on 7 January 2010

Preparation of organometallic ruthenium-arene-diaminotriazine complexes as binding agents to DNA.

scientific article

Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide

scientific article

Role of haemoglobin in the protection of cultured lymphocytes against diepoxybutane (DEB), assessed by in vitro induced chromosome breakage

scientific article published in April 2003

SNPs/pools: a methodology for the identification of relevant SNPs in breast cancer epidemiology

scientific article published on 24 October 2011

Stereochemical effects in the metabolic activation of nitrosopiperidines: correlations with genotoxicity.

scientific article published in March 2004

Styrene-oxide N-terminal valine haemoglobin adducts as biomarkers of occupational exposure to styrene

scientific article published on 15 June 2007

Styrene-oxide N-terminal valine haemoglobin adducts in reinforced plastic workers: possible influence of genetic polymorphism of drug-metabolising enzymes

scientific article published on 05 May 2007

The Brazilian Founder MutationTP53p.R337H is Uncommon in Portuguese Women Diagnosed with Breast Cancer

scientific article published on 23 July 2014

The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms in individual susceptibility to well-differentiated thyroid cancer

scientific article

The role of ERCC2 polymorphisms in breast cancer risk

scientific article published on 01 October 2006

The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.

scientific article published in September 2009

The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk.

scientific article published on October 2010

The role of foetal red blood cells in protecting cultured lymphocytes against diepoxybutane-induced chromosome breaks.

scientific article published on 27 December 2005

Three new labdanes isolated from Eragrostis viscosa

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