List of works - Michael Schnürch

A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry

scientific article published on 01 August 2018

Allosteric GABAA Receptor Modulators-A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility

scientific article published on 24 February 2020

Application of continuous flow and alternative energy devices for 5-hydroxymethylfurfural production

scientific article published on 14 January 2011

Aryl Bromides and Aryl Chlorides for the Direct Arylation of Benzylic Amines Mediated by Ruthenium(II)

scientific article published on 22 March 2013

Biocompatible metal-assisted C-C cross-coupling combined with biocatalytic chiral reductions in a concurrent tandem cascade

Continuous Formation of Limonene Carbonates in Supercritical Carbon Dioxide

scientific article published in 2022

Corrigendum to "Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands" [Bioorg. Med. Chem. Lett. 25/2 (2015) 400-403].

scientific article published on 20 February 2015

Counterion Enhanced Organocatalysis: A Novel Approach for the Asymmetric Transfer Hydrogenation of Enones

scientific article published on 15 June 2020

Counterion-Enhanced Pd/Enamine Catalysis: Direct Asymmetric α-Allylation of Aldehydes with Allylic Alcohols by Chiral Amines and Achiral or Racemic Phosphoric Acids

scientific article published on 15 December 2020

Design and Synthesis of a Compound Library Exploiting 5-Methoxyleoligin as Potential Cholesterol Efflux Promoter

scientific article published on 04 February 2020

Direct Arylation of Benzo[b]furan and Other Benzo-Fused Heterocycles.

scientific article

Direct Functionalization of C-H Bonds by Iron, Nickel, and Cobalt Catalysis.

scientific article published on 7 June 2017

Direct functionalization of (un)protected tetrahydroisoquinoline and isochroman under iron and copper catalysis: two metals, two mechanisms

scientific article

Efforts to induce cardiac electrophysiological properties in skeletal myoblasts in vitro.

scientific article published on 5 November 2008

Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABA Receptors

scientific article published on 23 July 2018

Expansion of the Concept of Nonlinear Effects in Catalytic Reactions Beyond Asymmetric Catalysis

scientific article published on 02 March 2016

Exploration of C-H and N-H-bond functionalization towards 1-(1,2-diarylindol-3-yl)tetrahydroisoquinolines

scientific article published on 15 September 2014

Extraction techniques for bioactive compounds of cannabis

scientific article published in 2023

Facile, solvent and ligand free iron catalyzed direct functionalization of N-protected tetrahydroisoquinolines and isochroman

scientific article published on 22 October 2010

First selective direct mono-arylation of piperidines using ruthenium-catalyzed C-H activation.

scientific article published on 3 April 2013

Halogenated 2'-chlorobithiazoles via Pd-catalyzed cross-coupling reactions

scientific article published on 01 May 2006

Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface

scientific article published on May 2013

Improved simplicity and practicability in copper-catalyzed alkynylation of tetrahydroisoquinoline

scientific article published on 9 December 2016

Investigations into the Kinetic Modeling of the Direct Alkylation of Benzylic Amines: Dissolution of K2CO3 Is Responsible for the Observation of an Induction Period

scientific article published on 10 August 2015

Investigations of the generality of quaternary ammonium salts as alkylating agents in direct C-H alkylation reactions: solid alternatives for gaseous olefins

scientific article published on 01 April 2019

Investigations of the halogen dance reaction on N-substituted 2-thiazolamines.

scientific article published in January 2005

Leoligin-inspired synthetic lignans with selectivity for cell-type and bioactivity relevant for cardiovascular disease

scientific article published on 14 May 2019

Linked magnolol dimer as a selective PPARγ agonist - Structure-based rational design, synthesis, and bioactivity evaluation

scientific article

Magnolol dimer-derived fragments as PPARγ-selective probes

scientific article published on 01 October 2018

Mechanistic and Kinetic Studies of the Direct Alkylation of Benzylic Amines: A Formal C(sp(3))-H Activation Proceeds Actually via a C(sp(2))-H Activation Pathway

scientific article published on 8 December 2014

Mechanistic investigations and substrate scope evaluation of ruthenium-catalyzed direct sp3 arylation of benzylic positions directed by 3-substituted pyridines

scientific article

Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands

scientific article

Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes.

scientific article

Novel and efficient access to phenylamino-pyrimidine type protein kinase C inhibitors utilizing a Negishi cross-coupling strategy.

scientific article published in June 2005

One-pot synthesis of triazines as potential agents affecting cell differentiation.

scientific article

Palladium(II)-Catalyzed Regioselective Ortho Arylation of sp(2) C-H Bonds of N-Aryl-2-amino Pyridine Derivatives

scientific article published on 13 June 2012

Photocatalytic deaminative benzylation and alkylation of tetrahydroisoquinolines with N-alkylpyrydinium salts

scientific article published on 21 April 2020

Quaternary Ammonium Salts as Alkylating Reagents in C-H Activation Chemistry

scientific article published on 07 August 2017

Rhodium-catalyzed direct alkylation of benzylic amines using alkyl bromides

scientific article published on 13 November 2018

Ruthenium catalyzed decarbonylative arylation at sp3 carbon centers in pyrrolidine and piperidine heterocycles

scientific article published on 6 September 2007

Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates

scientific article published on 26 March 2012

Ruthenium(II)-catalyzed sp3 C-H bond arylation of benzylic amines using aryl halides

scientific article published on 12 July 2012

SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2– Benzodiazepine Site

scientific article published on 08 August 2018

Selective Ru(0)-catalyzed deuteration of electron-rich and electron-poor nitrogen-containing heterocycles

scientific article published on 24 April 2012

Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells

scientific article

Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes

scientific article published on 31 July 2020

Synthesis of 5-arylated N-arylthiazole-2-amines as potential skeletal muscle cell differentiation promoters

scientific article published on 02 February 2011

Tandem catalysis: from alkynoic acids and aryl iodides to 1,2,3-triazoles in one pot

scientific article published on 10 March 2011

Targeting aphA : a new high-throughput screening assay identifies compounds that reduce prime virulence factors of Vibrio cholerae.

scientific article published on 12 May 2016

VUT-MK142 : a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes.

scientific article published on August 2013

List of works by Michael Schnürch

A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry

Allosteric GABAA Receptor Modulators-A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility

Application of continuous flow and alternative energy devices for 5-hydroxymethylfurfural production

Aryl Bromides and Aryl Chlorides for the Direct Arylation of Benzylic Amines Mediated by Ruthenium(II)

Biocompatible metal-assisted C-C cross-coupling combined with biocatalytic chiral reductions in a concurrent tandem cascade

Continuous Formation of Limonene Carbonates in Supercritical Carbon Dioxide

Corrigendum to "Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands" [Bioorg. Med. Chem. Lett. 25/2 (2015) 400-403].

Counterion Enhanced Organocatalysis: A Novel Approach for the Asymmetric Transfer Hydrogenation of Enones

Counterion-Enhanced Pd/Enamine Catalysis: Direct Asymmetric α-Allylation of Aldehydes with Allylic Alcohols by Chiral Amines and Achiral or Racemic Phosphoric Acids

Design and Synthesis of a Compound Library Exploiting 5-Methoxyleoligin as Potential Cholesterol Efflux Promoter

Direct Arylation of Benzo[b]furan and Other Benzo-Fused Heterocycles.

Direct Functionalization of C-H Bonds by Iron, Nickel, and Cobalt Catalysis.

Direct functionalization of (un)protected tetrahydroisoquinoline and isochroman under iron and copper catalysis: two metals, two mechanisms

Efforts to induce cardiac electrophysiological properties in skeletal myoblasts in vitro.

Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABA Receptors

Expansion of the Concept of Nonlinear Effects in Catalytic Reactions Beyond Asymmetric Catalysis

Exploration of C-H and N-H-bond functionalization towards 1-(1,2-diarylindol-3-yl)tetrahydroisoquinolines

Extraction techniques for bioactive compounds of cannabis

Facile, solvent and ligand free iron catalyzed direct functionalization of N-protected tetrahydroisoquinolines and isochroman

First selective direct mono-arylation of piperidines using ruthenium-catalyzed C-H activation.

Halogenated 2'-chlorobithiazoles via Pd-catalyzed cross-coupling reactions

Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface

Improved simplicity and practicability in copper-catalyzed alkynylation of tetrahydroisoquinoline

Investigations into the Kinetic Modeling of the Direct Alkylation of Benzylic Amines: Dissolution of K2CO3 Is Responsible for the Observation of an Induction Period

Investigations of the generality of quaternary ammonium salts as alkylating agents in direct C-H alkylation reactions: solid alternatives for gaseous olefins

Investigations of the halogen dance reaction on N-substituted 2-thiazolamines.

Leoligin-inspired synthetic lignans with selectivity for cell-type and bioactivity relevant for cardiovascular disease

Linked magnolol dimer as a selective PPARγ agonist - Structure-based rational design, synthesis, and bioactivity evaluation

Magnolol dimer-derived fragments as PPARγ-selective probes

Mechanistic and Kinetic Studies of the Direct Alkylation of Benzylic Amines: A Formal C(sp(3))-H Activation Proceeds Actually via a C(sp(2))-H Activation Pathway

Mechanistic investigations and substrate scope evaluation of ruthenium-catalyzed direct sp3 arylation of benzylic positions directed by 3-substituted pyridines

Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands

Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes.

Novel and efficient access to phenylamino-pyrimidine type protein kinase C inhibitors utilizing a Negishi cross-coupling strategy.

One-pot synthesis of triazines as potential agents affecting cell differentiation.

Palladium(II)-Catalyzed Regioselective Ortho Arylation of sp(2) C-H Bonds of N-Aryl-2-amino Pyridine Derivatives

Photocatalytic deaminative benzylation and alkylation of tetrahydroisoquinolines with N-alkylpyrydinium salts

Quaternary Ammonium Salts as Alkylating Reagents in C-H Activation Chemistry

Rhodium-catalyzed direct alkylation of benzylic amines using alkyl bromides

Ruthenium catalyzed decarbonylative arylation at sp3 carbon centers in pyrrolidine and piperidine heterocycles

Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates

Ruthenium(II)-catalyzed sp3 C-H bond arylation of benzylic amines using aryl halides

SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2– Benzodiazepine Site

Selective Ru(0)-catalyzed deuteration of electron-rich and electron-poor nitrogen-containing heterocycles

Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells

Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes

Synthesis of 5-arylated N-arylthiazole-2-amines as potential skeletal muscle cell differentiation promoters

Tandem catalysis: from alkynoic acids and aryl iodides to 1,2,3-triazoles in one pot

Targeting aphA : a new high-throughput screening assay identifies compounds that reduce prime virulence factors of Vibrio cholerae.

VUT-MK142 : a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes.