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List of works by Francisco Fierro

A novel heptameric sequence (TTAGTAA) is the binding site for a protein required for high level expression of pcbAB, the first gene of the penicillin biosynthesis in Penicillium chrysogenum

scientific article published on 01 January 2000

Autonomously replicating plasmids carrying the AMA1 region in Penicillium chrysogenum

scientific article published on 01 April 1996

Characterisation of the gptA gene, encoding UDP N-acetylglucosamine: dolichol phosphate N-acetylglucosaminylphosphoryl transferase, from the filamentous fungus, Aspergillus niger

scientific article

Characterization and lysine control of expression of the lys1 gene of Penicillium chrysogenum encoding homocitrate synthase

scientific article

Characterization and nitrogen-source regulation at the transcriptional level of the gdhA gene of Aspergillus awamori encoding an NADP-dependent glutamate dehydrogenase.

scientific article

Characterization of the lys2 gene of Penicillium chrysogenum encoding alpha-aminoadipic acid reductase.

scientific article

Cloning and characterization of the gene cahB encoding a cephalosporin C acetylhydrolase from Acremonium chrysogenum.

scientific article published in October 2001

Direct involvement of the CreA transcription factor in penicillin biosynthesis and expression of the pcbAB gene in Penicillium chrysogenum.

scientific article published on 13 May 2014

Electrophoretic karyotype of the filamentous fungus Penicillium purpurogenum and chromosomal location of several xylanolytic genes

scientific article published on 01 December 2001

Electroporation of germinated conidia and young mycelium as an efficient transformation system for Acremonium chrysogenum

scientific article published on 25 June 2018

Expression of genes and processing of enzymes for the biosynthesis of penicillins and cephalosporins

scientific article

Expression of the cefG gene is limiting for cephalosporin biosynthesis in Acremonium chrysogenum

scientific article published on November 1, 1997

Filamentous fungi from extreme environments as a promising source of novel bioactive secondary metabolites

scientific article published on 9 September 2015

Gene organization and plasticity of the beta-lactam genes in different filamentous fungi

scientific article

Genome-wide analysis of differentially expressed genes from Penicillium chrysogenum grown with a repressing or a non-repressing carbon source.

scientific article published on 16 December 2005

Heterotrimeric Galpha protein Pga1 of Penicillium chrysogenum controls conidiation mainly by a cAMP-independent mechanism.

scientific article published in February 2008

Heterotrimeric Gα protein Pga1 from Penicillium chrysogenum triggers germination in response to carbon sources and affects negatively resistance to different stress conditions.

scientific article published on 10 December 2010

High efficiency transformation of Penicillium nalgiovense with integrative and autonomously replicating plasmids

scientific article published in January 2004

Identification of soluble forms of vascular endothelial growth factor receptors, sVEGFR-1 and sVEGFR-2, in bovine dominant follicles

scientific article published on 12 October 2011

Isolation of Penicillium nalgiovense strains impaired in penicillin production by disruption of the pcbAB gene and application as starters on cured meat products.

scientific article published in June 2003

Molecular genetics as a tool to remove bottlenecks in the biosynthesis of β-lactam antibiotics

scientific article published on 01 September 1996

Molecular mechanisms of chromosomal rearrangement in fungi.

scientific article

Mutants blocked in penicillin biosynthesis show a deletion of the entire penicillin gene cluster at a specific site within a conserved hexanucleotide sequence

scientific article published on 01 January 1996

NeVOmics: An Enrichment Tool for Gene Ontology and Functional Network Analysis and Visualization of Data from OMICs Technologies

article

Organization of the gene cluster for biosynthesis of penicillin in Penicillium nalgiovense and antibiotic production in cured dry sausages.

scientific article

Production of penicillin by fungi growing on food products: identification of a complete penicillin gene cluster in Penicillium griseofulvum and a truncated cluster in Penicillium verrucosum.

scientific article published on March 2002

Proteomic analysis of the signaling pathway mediated by the heterotrimeric Gα protein Pga1 of Penicillium chrysogenum.

scientific article published on 6 October 2016

RNAi-Mediated Specific Gene Silencing as a Tool for the Discovery of New Drug Targets in Giardia lamblia; Evaluation Using the NADH Oxidase Gene.

scientific article published on 3 November 2017

Reactive oxygen species regulate lovastatin biosynthesis in Aspergillus terreus during submerged and solid-state fermentations.

scientific article

Resolution of four large chromosomes in penicillin-producing filamentous fungi: the penicillin gene cluster is located on chromosome II (9.6 Mb) in Penicillium notatum and chromosome I (10.4 Mb) in Penicillium chrysogenum.

scientific article

Silencing of the aspergillopepsin B (pepB) gene of Aspergillus awamori by antisense RNA expression or protease removal by gene disruption results in a large increase in thaumatin production

scientific article published on July 2002

Solid-state and submerged fermentations show different gene expression profiles in cephalosporin C production by Acremonium chrysogenum

scientific article published on 07 June 2012

Stem-Loop RT-qPCR as an Efficient Tool for the Detection and Quantification of Small RNAs in Giardia lamblia.

scientific article published on 20 December 2016

The corpora lutea proangiogenic state of VEGF system components is turned to antiangiogenic at the later phase of the oestrous cycle in cows.

scientific article published on 17 September 2014

The heterotrimeric Galpha protein pga1 regulates biosynthesis of penicillin, chrysogenin and roquefortine in Penicillium chrysogenum

scientific article published on 01 November 2008

The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences

scientific article

The pga1 gene of Penicillium chrysogenum NRRL 1951 encodes a heterotrimeric G protein alpha subunit that controls growth and development.

scientific article published on 16 March 2007

The unprocessed preprotein form IATC103S of the isopenicillin N acyltransferase is transported inside peroxisomes and regulates its self-processing

scientific article published in April 2008

Transcriptional and bioinformatic analysis of the 56.8 kb DNA region amplified in tandem repeats containing the penicillin gene cluster in Penicillium chrysogenum.

scientific article published on 18 May 2006

Validation of housekeeping genes as an internal control for gene expression studies in Giardia lamblia using quantitative real-time PCR.

scientific article published on 14 January 2016

Yeast HXK2 gene reverts glucose regulation mutation of penicillin biosynthesis in P. chrysogenum

scientific article published on 9 October 2014

[Role of G-protein alpha sub-units in the morphogenic processes of filamentous Ascomycota fungi].

scientific article