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List of works by Eduardo Díaz-Rubio

5-fluorouracil as a protracted continuous infusion plus irinotecan (CPT-11) in patients with advanced colorectal cancer treated with fluoropyrimidine-based regimens as first line

scientific article published in August 2003

A 50-gene signature is a novel scoring system for tumor-infiltrating immune cells with strong correlation with clinical outcome of stage I/II non-small cell lung cancer

scientific article published on 10 October 2014

A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families

scientific article published on 3 May 2011

A breast cancer family from Spain with germline mutations in both the BRCA1 and BRCA2 genes.

scientific article published in August 2002

A double-blind, randomised comparison of the anti-emetic efficacy of two intravenous doses of dolasetron mesilate and granisetron in patients receiving high dose cisplatin chemotherapy.

scientific article published in May 1996

A panel discussion of controversies and challenges in the adjuvant treatment of colon cancer.

scientific article

A phase I, dose-finding study of irinotecan (CPT-11) short i.v. infusion combined with fixed dose of 5-fluorouracil (5-FU) protracted i.v. infusion in adult patients with advanced solid tumours

scientific article published on 26 October 2004

A phase II trial of weekly high dose continuous infusion 5-fluorouracil plus oral leucovorin in patients with advanced colorectal cancer. The Spanish Cooperative Group for Gastrointestinal Tumor Therapy (TTD).

scientific article published in August 1995

A polymorphism in the cytidine deaminase promoter predicts severe capecitabine-induced hand-foot syndrome

scientific article published on 16 February 2011

A preliminary report of a phase II trial. UFT plus oral folinic acid as therapy for metastatic colorectal cancer in older patients. Spanish Group for the Treatment of Gastrointestinal Tumors (TTd Group).

scientific article

A prospective randomized trial of continuous infusion 5-fluorouracil (5-FU) versus 5-FU plus cisplatin in patients with advanced colorectal cancer. A trial of the Spanish Cooperative Group for Digestive Tract Tumor Therapy (T.T.D.)

scientific article published in February 1992

A randomized study of navelbine compared to navelbine and cisplatin compared to vindesine and cisplatin in the treatment of inoperable non-small-cell lung carcinoma. The results of a European multicenter study including 612 patients

scientific article

APC Yin-Yang haplotype associated with colorectal cancer risk.

scientific article

About 1% of the breast and ovarian Spanish families testing negative for BRCA1 and BRCA2 are carriers of RAD51D pathogenic variants

scientific article published on May 2014

Acute and anticipatory emesis in breast cancer patients

scientific article published on September 1996

Adjuvant chemotherapy for early-stage non-small-cell lung cancer. Single-centre experience and literature review.

scientific article published on September 2008

Adjuvant treatment of colorectal cancer (current expert opinion derived from the Third International Conference: Perspectives in Colorectal Cancer, Dublin, 2001).

scientific article published in July 2002

Alternative splicing and molecular characterization of splice site variants: BRCA1 c.591C>T as a case study.

scientific article published on 5 November 2009

An EORTC Gastrointestinal Group phase III evaluation of combinations of methyl-CCNU, 5-fluorouracil, and adriamycin in advanced gastric cancer

scientific article published in September 1987

Analysis of BRCA1 and BRCA2 genes in Spanish breast/ovarian cancer patients: a high proportion of mutations unique to Spain and evidence of founder effects

scientific article published in October 2003

Analysis of the Oxidative Damage Repair Genes NUDT1, OGG1, and MUTYH in Patients from Mismatch Repair Proficient HNPCC Families (MSS-HNPCC)

scientific article published on 25 February 2011

Ask the Experts: NICE guidance on the diagnosis and treatment of colorectal cancer

scientific article published in August 2012

Assessment of Topoisomerase II α status in breast cancer by quantitative PCR, gene expression microarrays, immunohistochemistry, and fluorescence in situ hybridization

scientific article

Assignment of tumor subtype by genomic testing and pathologic-based approximations: implications on patient's management and therapy selection.

scientific article published on 2 August 2013

Association Between BRCA1 Mutations and Ratio of Female to Male Births in Offspring of Families With Breast Cancer, Ovarian Cancer, or Both

scientific article published in The Journal of the American Medical Association

Association between BRCA1 and BRCA2 mutations and cancer phenotype in Spanish breast/ovarian cancer families: implications for genetic testing

scientific article published in February 2002

Association of K-ras codon 12 transversions with short survival in non-small cell lung cancer

scientific article published in December 1996

Aztreonam in association with piperacillin as an empirical antibiotic-treatment in febrile granulocytopenic patients with solid tumors ⬇️

scientific article published on January 1, 1994

BRCA1 Alternative splicing landscape in breast tissue samples.

scientific article

BRCA2 gene mutations and coagulation-associated biomarkers

scientific article published in March 2016

BRCA2gene: a candidate for clinical testing in familial colorectal cancer type X

scientific article published on 18 June 2014

Bevacizumab in combination with metronomic chemotherapy in patients with anthracycline- and taxane-refractory breast cancer.

scientific article published in October 2008

Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study.

scientific article

Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database.

scientific article

Brain metastases in metastatic breast cancer patients receiving trastuzumab-based therapies.

scientific article

Brain metastasis and carcinomatous meningitis from vulvar squamous cell carcinoma: case report

scientific article

Breast cancer: complete response with the combination of sunitinib and trastuzumab in a patient with grade III ductal carcinoma.

scientific article published in January 2010

Breast metastases as the first sign of recurrence of a cutaneous melanoma

scientific article published in January 2006

C8-T1 Radiculopathy Due to an Intradural Extramedullary Metastasis of a Pancreatic Neuroendocrine Tumor: Case Report and Review of the Literature.

scientific article published on May 2016

Cancer risk and overall survival in mismatch repair proficient hereditary non-polyposis colorectal cancer, Lynch syndrome and sporadic colorectal cancer

scientific article published on 6 September 2013

Capecitabine (Xeloda) in combination with oxaliplatin: a phase I, dose-escalation study in patients with advanced or metastatic solid tumors.

scientific article

Capecitabine versus 5-fluorouracil/folinic acid as adjuvant therapy for stage III colon cancer: final results from the X-ACT trial with analysis by age and preliminary evidence of a pharmacodynamic marker of efficacy ⬇️

scientific article published on September 6, 2011

Capecitabine/oxaliplatin, a safe and active first-line regimen for older patients with metastatic colorectal cancer: post hoc analysis of a large phase II study

scientific article published in July 2005

Capillary electrophoresis analysis of conventional splicing assays: IARC analytical and clinical classification of 31 BRCA2 genetic variants.

scientific article published on 28 October 2013

Carboplatin: an active drug in metastatic breast cancer.

scientific article

Cardiac metastasis from uterine leiomyosarcoma

scientific article published in May 2006

Celecoxib in a 12-year-old boy with familial adenomatous polyposis.

scientific article published in March 2010

Changes in the expression of plasma proteins associated with thrombosis in BRCA1 mutation carriers

scientific article published on 7 February 2012

Characterization of four novel BRCA2 large genomic rearrangements in Spanish breast/ovarian cancer families: review of the literature, and reevaluation of the genetic mechanisms involved in their origin

scientific article published on 21 March 2012

Chemotherapy for gastric cancer.

scientific article

Circulating tumor cell count is a prognostic factor in metastatic colorectal cancer patients receiving first-line chemotherapy plus bevacizumab: a Spanish Cooperative Group for the Treatment of Digestive Tumors study.

scientific article

Circulating tumor cells in colorectal cancer: correlation with clinical and pathological variables

scientific article published on 22 January 2008

Circulating tumor cells in metastatic breast cancer: timing of blood extraction for analysis

scientific article published on 01 October 2009

Circulating tumor cells in solid tumor in metastatic and localized stages

scientific article published on 01 November 2009

Circulating tumoral cells lack circadian-rhythm in hospitalized metastasic breast cancer patients

scientific article published on 01 November 2006

Circulating tumour cells in locally advanced breast cancer

scientific article published on 01 August 2009

Cis-platinum as second-line chemotherapy in advanced gastric adenocarcinoma. A phase II study of the EORTC gastrointestinal tract cancer cooperative group

scientific article published in November 1985

Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancérologie Digestive Database ⬇️

scientific article

Clinical evaluation of the simultaneous blockade of the dopamine D-2, Histamine H-1, and muscarinic cholinergic receptors in cancer chemotherapy-induced emesis: Results of a controlled trial

scientific article published in November 1986

Clinical practice guidelines on antiemetics in oncology.

scientific article

Clinical relevance of MMP-9, MMP-2, TIMP-1 and TIMP-2 in colorectal cancer

scientific article published in January 2005

Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data

scientific article

Clustering of cancer-related mutations in a subset ofBRCA1alleles: A study in the Spanish population

article

Colon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior.

scientific article

Colorectal cancer metastasis resectability after treatment with the combination of oxaliplatin, irinotecan and 5-fluorouracil. Final results of a phase II study

scientific article published in January 2008

Combination of oral idarubicin and prednimustine in advanced breast cancer: a phase II study

scientific article published in February 1997

Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors.

scientific article

Comparative Survival Analysis of p53 Gene Mutations and Protein Accumulation in Colorectal Cancer

scientific article published in 1998

Comparative study on the tolerance and efficacy of high doses of metoclopramide and clebopride in vomiting induced by cisplatin

scientific article published in June 1989

Comparison of Two Types of Liquid Biopsies in Patients With Hepatocellular Carcinoma Awaiting Orthotopic Liver Transplantation.

scientific article published in November 2015

Comprehensive annotation of splice junctions supports pervasive alternative splicing at the BRCA1 locus: a report from the ENIGMA consortium

scientific article published on 25 February 2014

Consensus on the treatment of pancreatic cancer in Spain.

scientific article published on May 2009

Continuing single-agent bevacizumab as maintenance therapy after induction XELOX (or FOLFOX) plus bevacizumab in first-line treatment of metastatic colorectal cancer

scientific article published on 16 October 2012

Cooperative role of telomerase activity and p16 expression in the prognosis of non-small-cell lung cancer

scientific article published on 01 January 2002

Correlation between response to neoadjuvant chemotherapy and survival in locally advanced breast cancer patients

article

Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma

scientific article published in February 2006

Cost-effectiveness analysis of interferon as adjuvant therapy in high-risk melanoma patients in Spain

scientific article published in December 2000

Cuirasse skin metastases secondary to gastric adenocarcinoma

scientific article published in June 2005

Current status of immunotherapy in neoplasms

scientific article published on December 31, 1975

Delayed hypersensitivity in postnecrotic and alcoholic cirrhosis

scientific article published in November 1978

Denaturing gradient gel electrophoresis-based analysis of loss of heterozygosity distinguishes nonobvious, deleterious BRCA1 variants from nonpathogenic polymorphisms

scientific article published in November 1999

Detection and quantification of circulating tumor cells in peripheral blood in patients with colon cancer

scientific article published in September 2007

Differential colorectal carcinogenesis: Molecular basis and clinical relevance

scientific article

Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications

scientific article published in February 2004

Documento de Consenso sobre el uso de factores estimuladores de colonias de granulocitos biosimilares para la corrección de la neutropenia asociada en pacientes con cáncer

scientific article published in March 2010

Doxorubicin in combination with fluorouracil and cyclophosphamide (i.v. FAC regimen, day 1, 21) versus methotrexate in combination with fluorouracil and cyclophosphamide (i.v. CMF regimen, day 1, 21) as adjuvant chemotherapy for operable breast canc

scientific article

Dual role of LOH at MMR loci in hereditary non-polyposis colorectal cancer?

scientific article published on 14 November 2005

ESMO consensus guidelines for the management of patients with metastatic colorectal cancer.

scientific article published on 5 July 2016

Effect of high RNA concentrations in real time reverse transcription quantitative polymerase chain reaction (RT-qPCR) yields.

scientific article

Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials

scientific article

Eight novel germlineMLH1andMSH2mutations in hereditary non-polyposis colorectal cancer families from Spain

scientific article published on 13 November 2001

Elderly patients with advanced colorectal cancer derive similar benefit without excessive toxicity after first-line chemotherapy with oxaliplatin-based combinations: comparative outcomes from the 03-TTD-01 phase III study.

scientific article

Elementary, My Dear Watson

scientific article published in May 2007

Emetic control in breast cancer patients receiving iv CMF

scientific article published in January 1996

Epidemiología de las tromboembolias pulmonares asintomáticas en los enfermos con cáncer

scientific article published in October 2004

Epididymal metastases as the first sign of a colon cancer recurrence

scientific article published in August 2005

Erlotinib versus pemetrexed for pretreated non-squamous non-small cell lung cancer patients in clinical practice

scientific article published on 20 February 2013

Etoposide (E) + epirebicin (E) + cisplatin (P) combination chemotherapy (EEP) In advanced gastric cancer: Negative impact on clinical outcome

scientific article published in December 1992

European edition of the NCCN clinical practice guidelines: relevance of the translation and adaptation into Spanish

scientific article published on 7 September 2016

Evaluation of clinical efficacy of new medical treatments in advanced colorectal cancer. Results of a workshop organized by the EORTC GITCCG. European Organization for Research and Treatment of Cancer. Gastrointestinal Tract Cancer Cooperative Group

scientific article published on 01 May 1998

Evaluation of the specificity of a lymphoid chalone ⬇️

scientific article published on November 1, 1975

Experimental study of the protective effect of glutathione against cisplatin-induced nephrotoxicity

scientific article published in November 1996

Extraction from bovine spleen of immunosuppressant with no activity on hematopoietic spleen colony formation

scientific article published in July 1973

Extrapyramidal reactions induced by intravenous metoclopramide

scientific article published on September 1984

Failure of high-dose tocopherol to prevent alopecia induced by doxorubicin

scientific article published on 2 October 1986

First-Line Cetuximab Plus Capecitabine in Elderly Patients with Advanced Colorectal Cancer: Clinical Outcome and Subgroup Analysis According toKRASStatus from a Spanish TTD Group Study ⬇️

scientific article published on February 23, 2012

First-line XELOX plus bevacizumab followed by XELOX plus bevacizumab or single-agent bevacizumab as maintenance therapy in patients with metastatic colorectal cancer: the phase III MACRO TTD study

scientific article published on 10 January 2012

First-line single-agent cetuximab in elderly patients with metastatic colorectal cancer. A phase II clinical and molecular study of the Spanish group for digestive tumor therapy (TTD).

scientific article published on 29 December 2009

Frequency and variability of genomic rearrangements on MSH2 in Spanish Lynch Syndrome families.

scientific article published on 11 September 2013

Gastrointestinal Tract Cancer Liaison Office: an attempt to organise clinical research in Europe

scientific article

Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors.

scientific article published in May 2002

Genomic predictors of response to doxorubicin versus docetaxel in primary breast cancer

scientific article published on 5 April 2011

Genomic rearrangements at the BRCA1 locus in Spanish families with breast/ovarian cancer.

scientific article published on 22 June 2006

Glutathione S-transferase P1 c.313A > G polymorphism could be useful in the prediction of doxorubicin response in breast cancer patients.

scientific article published on 2 November 2011

Glutathione administration against cisplatin-induced nephrotoxicity does not modify its cytotoxic activity

scientific article published on 01 September 1997

Guidelines for the detection and treatment of liver metastases of colorectal cancer.

scientific article

Guides for adjuvant treatment of colon cancer. TTD Group (Spanish Cooperative Group for Gastrointestinal Tumor Therapy).

scientific article published in February 2006

How health-related quality of life assessment should be used in advanced colorectal cancer clinical trials

scientific article published on 18 April 2017

Iatrogenic intestinal obstruction: a rare complication of capsule endoscopy in a patient with familial adenomatous polyposis.

scientific article published in February 2007

Identification of E545k mutation in plasma from a PIK3CA wild-type metastatic breast cancer patient by array-based digital polymerase chain reaction: Circulating-free DNA a powerful tool for biomarker testing in advance disease

scientific article published on 27 April 2015

Ifosfamide encephalopathy and methylene-blue: a case report

scientific article published on August 1996

Ifosfamide in advanced epidermoid head and neck cancer

scientific article published in 1993

Immediate vs. delayed imipenem treatment in cancer patients with profound neutropenia induced by high-dose chemotherapy: results of a randomized study.

scientific article published on September 2002

Immunohistochemistry and microsatellite instability testing for selecting MLH1, MSH2 and MSH6 mutation carriers in hereditary non-polyposis colorectal cancer.

scientific article

Immunomagnetic quantification of circulating tumoral cells in patients with prostate cancer: clinical and pathological correlation

scientific article published on 01 January 2010

Impact of cetuximab in current treatment of metastatic colorectal cancer.

scientific article published on 30 January 2014

Individual patient data analysis of progression-free survival versus overall survival as a first-line end point for metastatic colorectal cancer in modern randomized trials: findings from the analysis and research in cancers of the digestive system d

scientific article published in January 2015

Interstitial Pneumonitis and Lung Fibrosis during Adjuvant Treatment of Melanoma with Interferon Alpha according to the Kirkwood Schedule

scientific article published in 2005

Introduction. Critical role of anti-angiogenesis and VEGF inhibition in colorectal cancer.

scientific article

Irinotecan (CPT-11) in metastatic colorectal cancer patients resistant to 5-fluorouracil (5-FU): a phase II study

scientific article published in October 2003

Irinotecan in combination with fluorouracil in a 48-hour continuous infusion as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a Spanish Cooperative Group for the Treatment of Digestive Tumors study.

scientific article

Irinotecan-Cetuximab-Bevacizumab as a Salvage Treatment in Heavily Pretreated Metastatic Colorectal Cancer Patients: A Retrospective Observational Study

scientific article published in 2011

Is trastuzumab-induced cardiotoxicity involved in onco-cardiology outcome?

scientific article published in July 2011

LAS 30451: A novel 5-HT3 antagonist

scientific article published in January 1993

La investigación traslacional en la oncología clínica: retos y oportunidades

scientific article published in March 2010

Lack of Germ-line Mutations at the Specific BRCA1-IRIS Coding Sequence in 114 Spanish High-risk Breast/ovarian Families

scientific article published in November 2005

Laparotomic eventration or colonic prolapse after chemotherapy-induced emesis.

scientific article published on March 1988

Lapatinib plus trastuzumab in pretreated human epidermal growth factor receptor 2-positive metastatic breast cancer.

scientific article

Lesión quística en pared torácica en un paciente con carcinoma epidermoide de base de lengua

scientific article published in January 2001

Lethal cardiac toxicity after cisplatin and 5-fluorouracil chemotherapy. Report of a case with necropsy study

scientific article

Limited family structure and triple-negative breast cancer (TNBC) subtype as predictors of BRCA mutations in a genetic counseling cohort of early-onset sporadic breast cancers.

scientific article

Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or ovarian cancer families.

scientific article published on 05 December 2012

Lynch syndrome in a 15-year-old boy

scientific article published on 4 January 2008

MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway.

scientific article published on May 2010

Measuring quality of life in Spain.

scientific article published in November 2001

Meningeal and brain metastases in primary malignant pericardial mesothelioma

scientific article published in September 1994

Metastatic colorectal cancer: integrating irinotecan into combination and sequential chemotherapy.

scientific article

Microsatellite instability correlates with negative expression of estrogen and progesterone receptors in sporadic breast cancer

scientific article published on 01 January 2000

Milkersson-Rosenthal syndrome: contribution of a case with immunologic studies

scientific article

Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways.

scientific article published on October 2007

Molecular haplotyping of tandem single nucleotide polymorphisms by allele-specific PCR

scientific article published in May 2007

Molecular markers and biological targeted therapies in metastatic colorectal cancer: expert opinion and recommendations derived from the 11th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2009.

scientific article published in June 2010

Mutant BRCA1 alleles transmission: different approaches and different biases

scientific article published in January 2005

Neoadjuvant therapy with cisplatin/fluorouracil vs cisplatin/UFT in locally advanced squamous cell head and neck cancer

scientific article published on September 1, 1997

Neutropenic enteritis - a 2-case report and literature-review.

scientific article

New challenges in kidney cancer management: integration of surgery and novel therapies.

scientific article published on March 2015

New chemotherapeutic advances in pancreatic, colorectal, and gastric cancers.

scientific article published on January 2004

New mutation in the hMSH2 gene in a Spanish Muir-Torre syndrome

scientific article published on 01 September 2000

New target-based agents involve new clinical trial designs.

scientific article published on August 2006

Nuevas estrategias de mejora en la accesibilidad a las pruebas de laboratorio de los pacientes en oncología

scientific article published in July 2013

Oncological Evaluation by Positron-emission Tomography, Circulating Tumor Cells and Alpha Fetoprotein in Patients With Hepatocellular Carcinoma on the Waiting List for Liver Transplantation.

scientific article published in November 2016

Oncological translational research in the Spanish national health system: the INTRO study.

scientific article

Oncologists’ perceptions of cancer pain management in Spain: The real and the ideal

scientific article published in April 2007

Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-Base

article

Osteonecrosis of the jaw as an adverse bisphosphonate event: three cases of bone metastatic prostate cancer patients treated with zoledronic acid

scientific article published in September 2007

Oxaliplatin as single agent in previously untreated colorectal carcinoma patients: A phase II multicentric study

scientific article published on 01 January 1998

Oxaliplatin: results in colorectal carcinoma.

scientific article

Paclitaxel plus vinorelbine in metastatic breast Ca patients with contraindications to receive anthracyclines.

scientific article published on January 1998

Paclitaxel plus vinorelbine: an active regimen in metastatic breast cancer patients with prior anthracycline exposure.

scientific article published on January 2000

Parity and the risk of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers

scientific article published on 16 April 2009

Pharmacogenetic approach for capecitabine or 5-fluorouracil selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer

scientific article published on 28 April 2008

Pharmacokinetic characterization of mitonafide in man.

scientific article published in March 1992

Phase 1b Dose Escalation Study of Erlotinib in Combination with Infusional 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Advanced Solid Tumors

scientific article published on 15 January 2007

Phase I study of mitonafide with a 3-day administration schedule: early interruption due to severe central nervous system toxicity

scientific article published in January 1994

Phase I study of the combination of oxaliplatin, irinotecan and continuous infusion 5-fluorouracil in digestive tumors

scientific article

Phase I-II study of paclitaxel, cisplatin, and gemcitabine in advanced transitional-cell carcinoma of the urothelium. Spanish Oncology Genitourinary Group.

scientific article

Phase I/II trial of irinotecan plus high-dose 5-fluorouracil (TTD regimen) as first-line chemotherapy in advanced colorectal cancer

scientific article published in April 2004

Phase II Study of Trabectedin in Pretreated Patients with Advanced Colorectal Cancer

scientific article published on 01 May 2007

Phase II open-label study of erlotinib in combination with gemcitabine in unresectable and/or metastatic adenocarcinoma of the pancreas: relationship between skin rash and survival (Pantar study).

scientific article

Phase II study of mitonafide in non-small cell lung cancer (NSCLC).

scientific article published in January 1996

Phase II study of pegylated liposomal doxorubicin plus vinorelbine in breast cancer with previous anthracycline exposure.

scientific article

Phase II trial of UFT activity in pretreated breast cancer patients

scientific article published in December 1993

Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer

scientific article published in November 2007

Phase II trial of miniDOX (reduced dose docetaxel-oxaliplatin-capecitabine) in "suboptimal" patients with advanced gastric cancer (AGC). TTD 08-02.

scientific article published on 10 December 2014

Phase III Study of Capecitabine Plus Oxaliplatin Compared With Continuous-Infusion Fluorouracil Plus Oxaliplatin As First-Line Therapy in Metastatic Colorectal Cancer: Final Report of the Spanish Cooperative Group for the Treatment of Digestive Tumor

article

Platinum-based adjuvant chemotherapy on moderate- and high-risk stage I and II epithelian ovarian cancer patients. Long-term single institution experience and literature review.

scientific article published on February 2011

Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity

scientific article published on 15 February 2014

Post-hepatitis hyperbilirubinemia

scientific article published in November 1972

Practical prognostic index for patients with metastatic recurrent breast cancer: retrospective analysis of 2,322 patients from the GEICAM Spanish El Alamo Register

scientific article published on 10 January 2010

Prednimustine-Induced Myoclonus—a Report of Three Cases

scientific article published in January 1994

Preliminary results of a phase II trial of chronic oral etoposide in breast cancer

scientific article published in January 1993

Preliminary results. UFT/methotrexate/leucovorin for breast Ca patients in progression after HDCT/PBPC support

scientific article published on September 1997

Pretreatment prognostic factors for survival in patients with advanced urothelial tumors treated in a phase I/II trial with paclitaxel, cisplatin, and gemcitabine.

scientific article

Prevalence of germline mutations ofMLH1 andMSH2 in hereditary nonpolyposis colorectal cancer families from Spain

article

Prevalence of p53 overexpression or mutations, but not k-ras mutations, in recurrent patients affected by colorectal-carcinoma.

scientific article

Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomised trials from the Analysis and Research in Cancers of the Digestive System (ARCAD) database ⬇️

scientific article

Prognostic Value of BRAF, PI3K, PTEN, EGFR Copy Number, Amphiregulin and Epiregulin Status in Patients with KRAS Codon 12 Wild-Type Metastatic Colorectal Cancer Receiving First-Line Chemotherapy with Anti-EGFR Therapy.

scientific article published on 4 September 2015

Prognostic and predictive markers of benefit from adjuvant chemotherapy in early-stage non-small cell lung cancer.

scientific article published on July 2009

Prognostic factors in invasive lobular carcinoma of the breast: a multivariate analysis. A multicentre study after seventeen years of follow-up

article

Prognostic value of DNA quantification in early epithelial ovarian carcinoma

scientific article published in March 2001

Progress in metastatic colorectal cancer: growing role of cetuximab to optimize clinical outcome.

scientific article published on August 2010

Progressive loss of antiemetic efficacy during subsequent courses of chemotherapy

scientific article published in February 1992

Proteins in human bronchial washings (author's transl)

scientific article published in December 1972

Quality Indicators to Assure and Improve Cancer Care in Spain Using the Delphi Technique

scientific article published on May 2016

Randomized study of weekly irinotecan plus high-dose 5-fluorouracil (FUIRI) versus biweekly irinotecan plus 5-fluorouracil/leucovorin (FOLFIRI) as first-line chemotherapy for patients with metastatic colorectal cancer: a Spanish Cooperative Group fo

scientific article

Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with weekly high-dose 48-hour continuous-infusion fluorouracil for advanced colorectal cancer: A Spanish Cooperative Group for Gastrointestinal Tumor Therapy (TTD) study

article

Randomized, double-blind cross-over study of acute cisplatin-induced nausea and vomiting, comparing a new schedule of the combination of metoclopramide and methylprednisolone versus metoclopramide alone

scientific article published in September 1990

Reassessing the TARBP2 mutation rate in hereditary nonpolyposis colorectal cancer.

scientific article

Recommendations and expert opinion on the adjuvant treatment of colon cancer in Spain ⬇️

scientific article published on November 1, 2011

Recommendations and expert opinion on the treatment of locally advanced rectal cancer in Spain.

scientific article published on December 2011

Renal cell cancer metastases to esophagus and stomach successfully treated with radiotherapy and pazopanib

scientific article published in January 2015

Results of two controlled studies on antiemetic combination against vomiting induced by 5-fluorouracil

scientific article published on October 1987

Retrospective evaluation of toxicity in three different schedules of adjuvant chemotherapy for patients with resected colorectal cancer. TTD Spanish Cooperative Group

article

Risk-Adapted Adjuvant Chemotherapy After Concomitant Fluoropyrimidine-Radiotherapy Neoadjuvant Treatment for Patients With Resectable CT3-4 or N+ Rectal Cancer: Five-Year Disease-Free Survival Results of a Single-Center Series.

scientific article published on 24 August 2015

Risk-reduction surgery in BRCA mutation carriers in a Spanish population: adherence and results.

scientific article published in October 2008

Role of Kras status in patients with metastatic colorectal cancer receiving first-line chemotherapy plus bevacizumab: a TTD group cooperative study

scientific article

Role of cetuximab in first-line treatment of metastatic colorectal cancer

scientific article published on April 2014

Role of circulating tumor cells as prognostic marker in resected stage III colorectal cancer

scientific article published on 15 December 2014

Screening for large rearrangements of the BRCA2 gene in Spanish families with breast/ovarian cancer.

scientific article published on 25 October 2006

Second-line therapy for advanced pancreatic cancer: a review of the literature and future directions.

scientific article published on 15 September 2009

Severe perirenal hematoma in a patient with a single kidney treated with sunitinib for metastatic pancreatic neuroendocrine tumor

scientific article published in 2012

Short report: Emesis during past pregnancy: A new prognostic factor in chemotherapy-induced emesis

scientific article published in 1990

Should capecitabine replace 5-fluorouracil in the first-line treatment of metastatic colorectal cancer?

scientific article published on May 2014

Significance of the immunohistochemical detection of lymph node micrometastases in Stage II Colorectal Carcinoma

scientific article published in September 2006

Social value of a quality-adjusted life year (QALY) in Spain: the point of view of oncologists

scientific article published on 13 June 2014

Sorafenib for non-selected patient population with advanced hepatocellular carcinoma: efficacy and safety data according to liver function

scientific article

Spanish Society of Medical Oncology consensus for the use of haematopoietic colony-stimulating factors in cancer patients.

scientific article published on July 2009

Spanish Society of Medical Oncology consensus on the use of erythropoietic stimulating agents in anaemic cancer patients.

scientific article

Spanish family study on hereditary breast and/or ovarian cancer: Analysis of theBRCA1 gene

scientific article published in 2000

Stromelysin-1 promoter mutations impair gelatinase B activation in high microsatellite instability sporadic colorectal tumors

scientific article published in July 2002

Successful rectal cancer local recurrence radiofrequency ablation

scientific article published in May 2008

Superior vena cava syndrome in microcytic carcinoma of the lung: incidence, treatment response and prognostic importance

scientific article published in October 1991

TTD consensus document on the diagnosis and management of exocrine pancreatic cancer.

scientific article published on 12 April 2014

Tegafur and uracil plus leucovorin in advanced colorectal cancer: a phase II trial

scientific article

Telomere function in colorectal cancer.

scientific article published on October 2009

The Antiemetic Efficacy of Thiethylperazine and Methylprednisolone Versus Thiethylperazine and Placebo in Breast Cancer Patients Treated with Adjuvant Chemotherapy (Fluorouracil, Doxorubicin and Cyclophosphamide): A randomized, double-blind, cross-ov

scientific article published in January 1991

The CHEK2 1100delC allele is not relevant for risk assessment in HNPCC and HBCC Spanish families

scientific article published in June 2005

The Natural Course of Emesis After Carboplatin Treatment

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The Spanish experience with high-dose infusional 5-fluorouracil (5-FU) in colorectal cancer. The Spanish Cooperative Group For Gastrointestinal Tumor Therapy (TTD)

scientific article published on January 1, 1996

The diagnosis and management of gastric cancer: expert discussion and recommendations from the 12th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2010

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The diagnosis and management of rectal cancer: expert discussion and recommendations derived from the 9th World Congress on Gastrointestinal Cancer, Barcelona, 2007.

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The management of pancreatic cancer. Current expert opinion and recommendations derived from the 8th World Congress on Gastrointestinal Cancer, Barcelona, 2006

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The neo-adjuvant, surgical and adjuvant treatment of gastric adenocarcinoma. Current expert opinion derived from the Seventh World Congress on Gastrointestinal Cancer, Barcelona, 2005

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Therapeutic equivalence of single oral doses of dolasetron mesilate and multiple doses of ondansetron for the prevention of emesis after moderately emetogenic chemotherapy

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Topoisomerase 2 alpha: a real predictor of anthracycline efficacy?

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Trastuzumab associated with successive cytotoxic therapies beyond disease progression in metastatic breast cancer.

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Treatment of advanced ovarian cancer with cisplatin, adriamycin and cyclophosphamide (PAC)

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Treatment of cancer of the ovary in advanced stages (III and IV)

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Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging.

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Two consecutive phase II trials of biweekly oxaliplatin plus weekly 48-hour continuous infusion of nonmodulated high-dose 5-fluorouracil as first-line treatment for advanced colorectal cancer

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UFT in combination with oxaliplatin: clinical phase I study in patients with advanced or metastatic solid tumors.

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UFT plus or minus calcium folinate for metastatic colorectal cancer in older patients

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Use of granulocyte growth factors in solid tumours

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Venous International Assessment, VIA scale, validated classification procedure for the peripheral venous system.

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Weekly continuous infusion of 5-fluorouracil with oral leucovorin in metastatic breast cancer patients with primary resistance to doxorubicin.

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Weekly high-dose infusion of 5-fluorouracil in advanced colorectal cancer

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Working towards a consensus on the oncological approach of breakthrough pain: a Delphi survey of Spanish experts

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XELOX vs FOLFOX-4 as first-line therapy for metastatic colorectal cancer: NO16966 updated results.

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[Biomarkers and anti-EGFR therapies for KRAS wild-type tumors in metastatic colorectal cancer patients]

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[Does an effective adjuvant treatment in colorectal cancer exist?]

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[Epithelial cancer of the ovary. Current perspectives (1)]

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[Epithelial cancer of the ovary: current perspectives. (2)]

scientific article published on 15 September 1983

[Goodpasture's syndrome. Apropos of 2 new cases]

scientific article published on 01 August 1980

[Heterogeneity of blastogenic factors secreted by lymphocytes studied in vitro]

scientific article published on 30 November 1973

[High-dose chemotherapy with four drugs and peripheral blood progenitor cell autologous transplantation in disseminated breast cancer]

scientific article published on 6 December 1997

[Incidence and significance of monoclonal gammopathy in a Spanish nosocomial population]

scientific article published on 26 March 1983

[Induced urticaria by cyclophosphamide. Apropos of 2 cases]

scientific article published on 31 March 1980

[Monographies of the National Royal Academy of Medicine]

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[PET detection of recurring rectal adenocarcinoma in an unusual location. Case report]

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[Personalized medicine in oncology: one drug, one biomarker]

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[Study of 16 protein fractions in the bronchial mucus in chronic bronchitis]

scientific article published on 15 March 1973

[The behavior of immunoglobulins and other plasma proteins in chronic myeloid leukemia studied by immunological methods]

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[The challenge of cancer survival in adults: therapeutic progress from the perspective of the clinican]

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[Translational research in clinical oncology: challenges and opportunities]

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[Treatment of microcytic carcinoma of the lung with vincristine, adriamycin, cyclophosphamide and VP-16]

scientific article published in October 1986

p53 exon 5 mutations as a prognostic indicator of shortened survival in non-small-cell lung cancer ⬇️

scientific article published on January 1, 1997

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