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List of works by Boon Chin Heng

"Waste" follicular aspirate from fertility treatment--a potential source of human germline stem cells?

scientific article published in February 2005

17β-estradiol protects human eyelid-derived adipose stem cells against cytotoxicity and increases transplanted cell survival in spinal cord injury

scientific article published on 22 December 2013

3D-Printed Atsttrin-Incorporated Alginate/Hydroxyapatite Scaffold Promotes Bone Defect Regeneration with TNF/TNFR Signaling Involvement

scientific article

Aberrant profile of gene expression in cloned mouse embryos derived from donor cumulus nuclei

scientific article

Adhesion, proliferation, and gene expression profile of human umbilical vein endothelial cells cultured on bilayered polyelectrolyte coatings composed of glycosaminoglycans.

scientific article published on September 2010

Allogenous tendon stem/progenitor cells in silk scaffold for functional shoulder repair

scientific article published on 08 March 2012

An autologous cell lysate extract from human embryonic stem cell (hESC) derived osteoblasts can enhance osteogenesis of hESC.

scientific article

An overview and synopsis of techniques for directing stem cell differentiation in vitro.

scientific article published on 31 January 2004

Are stem cells inherently more prone to cryopreservation-induced apoptosis compared to ordinary somatic cells?

scientific article published on 17 December 2008

Biomedical Applications of Dental and Oral-Derived Stem Cells

scientific article published on 3 January 2017

Can RNA interference be used to expand the plasticity of autologous adult stem cells?

scientific article published on 14 September 2004

Can the high nuclear to cytoplasmic ratio of human embryonic stem cells make them more vulnerable to physical stress encountered with bulk-passage protocols?

scientific article published on 01 January 2005

Can the therapeutic advantages of allogenic umbilical cord blood-derived stem cells and autologous bone marrow-derived mesenchymal stem cells be combined and synergized?

scientific article published on 01 November 2006

Caspase inhibitor Z-VAD-FMK enhances the freeze-thaw survival rate of human embryonic stem cells

scientific article published on 01 October 2007

Cellular behavior of human mesenchymal stem cells cultured on single-walled carbon nanotube film

article by Chor Yong Tay et al published April 2010 in Carbon

Cellular uptake of Poly‐(D,L‐lactide‐co‐glycolide) (PLGA) nanoparticles synthesized through solvent emulsion evaporation and nanoprecipitation method ⬇️

scientific article published on January 21, 2011

Clinical outcome of fresh and vitrified-warmed blastocyst and cleavage-stage embryo transfers in ethnic Chinese ART patients

scientific article

Combined effects of TGFbeta1 and BMP2 in serum-free chondrogenic differentiation of mesenchymal stem cells induced hyaline-like cartilage formation.

scientific article

Combining RNA interference with PTD-fusion transcription factors: a novel integrated strategy for achieving trans-differentiation of adult stem cells?

scientific article published in January 2005

Combining transfusion of stem/progenitor cells into the peripheral circulation with localized transplantation in situ at the site of tissue/organ damage: a possible strategy to optimize the efficacy of stem cell transplantation therapy

scientific article published on 01 January 2005

Comments about possible use of human embryonic stem cell-derived cardiomyocytes to direct autologous adult stem cells into the cardiomyogenic lineage.

scientific article

Comparative cytotoxicity evaluation of lanthanide nanomaterials on mouse and human cell lines with metabolic and DNA-quantification assays.

scientific article published on September 2010

Comparison of enzymatic and non-enzymatic means of dissociating adherent monolayers of mesenchymal stem cells

scientific article published on 10 March 2009

Comparison of osteogenesis of human embryonic stem cells within 2D and 3D culture systems.

scientific article published on January 2008

Comparison of the response of human embryonic stem cells and their differentiated progenies to oxidative stress

scientific article published in August 2009

Composite scaffolds of nano-hydroxyapatite and silk fibroin enhance mesenchymal stem cell-based bone regeneration via the interleukin 1 alpha autocrine/paracrine signaling loop.

scientific article published on 14 February 2015

Could the transit-amplifying stage of stem cell differentiation be the most suited for transplantation purposes?

scientific article published on 01 January 2005

Culture media conditioned by heat-shocked osteoblasts enhances the osteogenesis of bone marrow-derived mesenchymal stromal cells.

scientific article published on May 2007

Cytotoxicity of hydroxyapatite nanoparticles is shape and cell dependent.

scientific article

Cytotoxicity of zinc oxide (ZnO) nanoparticles is influenced by cell density and culture format.

scientific article published on 12 October 2010

Differential resistance of human embryonic stem cells and somatic cell types to hydrogen peroxide-induced genotoxicity may be dependent on innate basal intracellular ROS levels

scientific article published on 9 July 2015

Differentiated fibroblastic progenies of human embryonic stem cells for toxicology screening.

scientific article published on March 2008

Differentiation therapy of cancer. Potential advantages over conventional therapeutic approaches targeting death of cancer/tumor cells

scientific article published on 05 August 2005

Directing endothelial differentiation of human embryonic stem cells via transduction with an adenoviral vector expressing the VEGF(165) gene.

scientific article published in June 2007

Directing stem cells into the keratinocyte lineage in vitro.

scientific article

Down-regulation of Rac GTPase-activating protein OCRL1 causes aberrant activation of Rac1 in osteoarthritis development

scientific article published on May 2015

Effect of Rho-associated kinase (ROCK) inhibitor Y-27632 on the post-thaw viability of cryopreserved human bone marrow-derived mesenchymal stem cells

scientific article published on 3 March 2009

Effect of cell-seeding density on the proliferation and gene expression profile of human umbilical vein endothelial cells within ex vivo culture.

scientific article

Effects of compatibility of deproteinized antler cancellous bone with various bioactive factors on their osteogenic potential

scientific article published on 3 September 2013

Effects of culture conditions and bone morphogenetic protein 2 on extent of chondrogenesis from human embryonic stem cells

scientific article published on 11 January 2007

Effects of deer age on the physicochemical properties of deproteinized antler cancellous bone: an approach to optimize osteoconductivity of bone graft

scientific article published on 04 June 2015

Effects of granulosa coculture on in-vitro oocyte meiotic maturation within a putatively less competent murine model

scientific article published in September 2004

Efficacy of hESC-MSCs in knitted silk-collagen scaffold for tendon tissue engineering and their roles.

scientific article

Electrospun scaffolds for multiple tissues regeneration in vivo through topography dependent induction of lineage specific differentiation.

scientific article

Electrostatic binding of nanoparticles to mesenchymal stem cells via high molecular weight polyelectrolyte chains

scientific article published in June 2009

Evaluation of human embryonic stem cells and their differentiated fibroblastic progenies as cellular models for in vitro genotoxicity screening

scientific article published on 23 May 2014

Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles ⬇️

scientific article published on June 9, 2011

Fetal and adult fibroblasts display intrinsic differences in tendon tissue engineering and regeneration.

scientific article

Functional biomaterials for cartilage regeneration.

scientific article published on 10 April 2012

G protein-coupled receptors revisited: therapeutic applications inspired by synthetic biology

scientific article published on 11 October 2013

Heterogeneity of baseline neural marker expression by undifferentiated mesenchymal stem cells may be correlated to donor age.

scientific article published on 28 January 2014

Histological evaluation of osteogenesis of 3D-printed poly-lactic-co-glycolic acid (PLGA) scaffolds in a rabbit model.

scientific article published on 11 February 2009

Human Embryonic Stem Cell-Derived Neural Lineages as In Vitro Models for Screening the Neuroprotective Properties of Lignosus rhinocerus (Cooke) Ryvarden

scientific article published on 19 August 2019

Human embryonic stem cells may display higher resistance to genotoxic stress as compared to primary explanted somatic cells.

scientific article published in June 2008

Hyaluronan binding to link module of TSG-6 and to G1 domain of aggrecan is differently regulated by pH.

scientific article

ING2 (inhibitor of growth protein-2) plays a crucial role in preimplantation development

scientific article published on 12 February 2015

Immunoliposome-mediated delivery of neomycin phosphotransferase for the lineage-specific selection of differentiated/committed stem cell progenies: potential advantages over transfection with marker genes, fluorescence-activated and magnetic affinit

scientific article published on 01 January 2005

In vitroassessment of cellular responses to rod-shaped hydroxyapatite nanoparticles of varying lengths and surface areas ⬇️

scientific article published on August 23, 2010

Incorporating protein transduction domains (PTD) within intracellular proteins associated with the 'stemness' phenotype. Novel use of such recombinant 'fusion' proteins to overcome current limitations of applying autologous adult stem cells in regen

scientific article published on 01 January 2005

Incorporating protein transduction domains (PTD) within recombinant 'fusion' transcription factors. A novel strategy for directing stem cell differentiation?

scientific article

Incorporation of bioactive polyvinylpyrrolidone-iodine within bilayered collagen scaffolds enhances the differentiation and subchondral osteogenesis of mesenchymal stem cells

scientific article published on 23 May 2013

Increased expression of nestin in human pterygial epithelium

scientific article published on 18 June 2013

Induced Pluripotent Stem Cells (iPSC)--can direct delivery of transcription factors into the cytosol overcome the perils of permanent genetic modification?

scientific article published on 01 January 2008

Induced adult stem (iAS) cells and induced transit amplifying progenitor (iTAP) cells-a possible alternative to induced pluripotent stem (iPS) cells?

scientific article

Induced pluripotent stem cells: a new tool for toxicology screening? ⬇️

scientific article published on 27 February 2009

Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo

scientific article

Intra-articular injection of human meniscus stem/progenitor cells promotes meniscus regeneration and ameliorates osteoarthritis through stromal cell-derived factor-1/CXCR4-mediated homing

scientific article published on 21 January 2014

Intra-articular transplantation of atsttrin-transduced mesenchymal stem cells ameliorate osteoarthritis development

scientific article published on 30 March 2015

Kinetics of cell death of frozen-thawed human embryonic stem cell colonies is reversibly slowed down by exposure to low temperature.

scientific article published in November 2006

Lentiviral-encoded shRNA silencing of proteoglycan decorin enhances tendon repair and regeneration within a rat model

scientific article

Local delivery of FTY720 in PCL membrane improves SCI functional recovery by reducing reactive astrogliosis.

scientific article published on 15 May 2015

Long-term effects of knitted silk-collagen sponge scaffold on anterior cruciate ligament reconstruction and osteoarthritis prevention.

scientific article published on 25 June 2014

Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: potential advantages over antibodies expressed within the intracellular environment (Intrabody)

scientific article published on 01 January 2005

Making cell-permeable recombinant telomerase (trans-telomerase) through fusion of its catalytic subunit (hTERT) with protein transduction domains (PTD): a possible strategy to overcome replicative senescence during ex vivo culture of primary explant

scientific article published on 01 January 2005

Mammalian oocyte polarity can be exploited for the automation of somatic cell nuclear transfer--in the development of a 'cloning biochip'.

scientific article published on 27 December 2005

Mechanical dissociation of human embryonic stem cell colonies by manual scraping after collagenase treatment is much more detrimental to cellular viability than is trypsinization with gentle pipetting.

scientific article published on May 2007

Mesenchymal stem cell sheets revitalize nonviable dense grafts: implications for repair of large-bone and tendon defects

scientific article published in July 2006

Mohawk promotes the tenogenesis of mesenchymal stem cells through activation of the TGFβ signaling pathway

scientific article

Neural Differentiation of Human Pluripotent Stem Cells for Nontherapeutic Applications: Toxicology, Pharmacology, and In Vitro Disease Modeling.

scientific article published on 25 May 2015

New insights on brain-derived neurotrophic factor epigenetics: from depression to memory extinction

scientific article published on 17 August 2020

New perspectives in chondrogenic differentiation of stem cells for cartilage repair.

scientific article published on 20 March 2006

Osteoarthritis and therapy.

scientific article

Osteoconductive effectiveness of bone graft derived from antler cancellous bone: an experimental study in the rabbit mandible defect model

scientific article

Osteogenic differentiation within intact human embryoid bodies result in a marked increase in osteocalcin secretion after 12 days of in vitro culture, and formation of morphologically distinct nodule-like structures.

scientific article published on August 2005

Physical regulation of stem cells differentiation into teno-lineage: current strategies and future direction.

scientific article published on 31 December 2014

Pluripotent Human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy.

scientific article published on 6 January 2016

Possible Advantages of Stem Cell Transfusion into the Peripheral Circulation, As Opposed to Localized Transplantation In Situ

scientific article published on 01 August 2005

Potential applications of intracellular antibodies (intrabodies) in stem cell therapeutics.

scientific article

Reduced mitotic activity at the periphery of human embryonic stem cell colonies cultured in vitro with mitotically-inactivated murine embryonic fibroblast feeder cells.

scientific article published in March 2005

Reduction in exposure of human embryos outside the incubator enhances embryo quality and blastulation rate.

scientific article published on 28 December 2009

Scaffold implants for the controlled release of heparan sulfate (HS) and other glycosaminoglycan (GAG) species: this could facilitate the homing of adult stem cells for tissue/organ regeneration.

scientific article published in January 2005

Seeding density matters: extensive intercellular contact masks the surface dependence of endothelial cell-biomaterial interactions

scientific article published on 08 January 2011

Slow-cooling protocols for microcapsule cryopreservation

scientific article published in June 2004

Soluble molecules are key in maintaining the immunomodulatory activity of murine mesenchymal stromal cells.

scientific article published on 16 January 2012

Strategies for directing the differentiation of stem cells into the osteogenic lineage in vitro.

scientific article published on 26 July 2004

Strategies for the cryopreservation of microencapsulated cells.

scientific article published on January 2004

Systemically Transplanted Bone Marrow-derived Cells Contribute to Dental Pulp Regeneration in a Chimeric Mouse Model

scientific article published on 10 December 2015

The analysis of intermolecular interactions in concentrated hyaluronan solutions suggest no evidence for chain-chain association

scientific article

The differentiation status of stem cells and their derivatives: a key consideration in transplantation medicine

scientific article published on 01 November 2004

The effect of decellularized matrices on human tendon stem/progenitor cell differentiation and tendon repair.

scientific article

The effect of incorporation of exogenous stromal cell-derived factor-1 alpha within a knitted silk-collagen sponge scaffold on tendon regeneration

scientific article published on 01 October 2010

The promotion of osteochondral repair by combined intra-articular injection of parathyroid hormone-related protein and implantation of a bi-layer collagen-silk scaffold.

scientific article published on 20 May 2013

Therapeutic angiogenesis by transplantation of human embryonic stem cell-derived CD133+ endothelial progenitor cells for cardiac repair

scientific article

Toxicity of zinc oxide (ZnO) nanoparticles on human bronchial epithelial cells (BEAS-2B) is accentuated by oxidative stress

scientific article published on 20 April 2010

Transcatheter injection-induced changes in human bone marrow-derived mesenchymal stem cells

scientific article published on 22 June 2009

Translating human embryonic stem cells from 2-dimensional to 3-dimensional cultures in a defined medium on laminin- and vitronectin-coated surfaces

scientific article published on 23 December 2011

Transplanted human embryonic stem cells as biological 'catalysts' for tissue repair and regeneration

scientific article published on 01 January 2005

Utilising human embryonic stem cells as "catalysts" for biological repair and regeneration. Challenges and some possible strategies

scientific article published on 01 May 2005

Utilizing stem cells for myocardial repair--to differentiate or not to differentiate prior to transplantation?

scientific article published on 01 July 2005

Vitrification of mouse embryos at 2-cell, 4-cell and 8-cell stages by cryotop method

scientific article

Vitrified-warmed blastocyst transfer cycles yield higher pregnancy and implantation rates compared with fresh blastocyst transfer cycles--time for a new embryo transfer strategy?

scientific article published on April 2011

Well-aligned chitosan-based ultrafine fibers committed teno-lineage differentiation of human induced pluripotent stem cells for Achilles tendon regeneration

scientific article published on 26 March 2015

Wnt and Rho GTPase signaling in osteoarthritis development and intervention: implications for diagnosis and therapy.

scientific article published on 11 July 2013

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