List of works - Gabriella Gobbi

Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood.

scientific article published on 3 November 2011

Alterations of the thalamo-cortical system in rats prenatally exposed to ethanol are prevented by concurrent administration of acetyl- l-carnitine

scientific article published on 01 November 1995

An index of 5-HT synthesis changes during early antidepressant treatment: alpha-[11C]methyl-L-tryptophan PET study

scientific article published on 6 September 2007

Anatomical and cellular localization of melatonin MT1 and MT2 receptors in the adult rat brain

scientific article

Antidepressant combination versus antidepressants plus second-generation antipsychotic augmentation in treatment-resistant unipolar depression

scientific article

Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis

scientific article

Antinociceptive properties of selective MT(2) melatonin receptor partial agonists

scientific article published on 7 July 2015

Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam

scientific article

Brain TRPV1: a depressing TR(i)P down memory lane?

scientific article published on 22 October 2008

Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

article

Cannabinoids and emotionality: a neuroanatomical perspective.

scientific article published on 27 July 2011

Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex.

scientific article published in October 2007

Characterization of serotonin neurotransmission in knockout mice: implications for major depression

scientific article published on January 2012

Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission

scientific article published on 5 December 2009

Chronic nandrolone decanoate exposure during adolescence affects emotional behavior and monoaminergic neurotransmission in adulthood

scientific article

Clonidine fails to modify dopaminergic neuronal activity during morphine withdrawal

scientific article published in October 2001

Clozapine blocks dopamine, 5-HT2 and 5-HT3 responses in the medial prefrontal cortex: an in vivo microiontophoretic study.

scientific article

Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress

scientific article published on 15 January 2009

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

scientific article published on 13 August 2006

Differential Function of Melatonin MT and MT Receptors in REM and NREM Sleep

Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery.

scientific article published in April 2018

Dysfunction of serotonergic activity and emotional responses across the light-dark cycle in mice lacking MT2 receptors

scientific article published on 01 April 2020

Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission

scientific article published on 22 February 2012

Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs

scientific article

Effects of quetiapine and olanzapine in patients with psychosis and violent behavior: a pilot randomized, open-label, comparative study

scientific article

Efficacy of Topiramate, Valproate, and Their Combination on Aggression/Agitation Behavior in Patients With Psychosis

scientific article published on 01 October 2006

Electrophysiological characterization of dopamine neuronal activity in the ventral tegmental area across the light-dark cycle

scientific article published on 4 July 2014

Endocannabinoids in the treatment of mood disorders: evidence from animal models

scientific article published on January 2009

Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review

scientific article

Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice

scientific article

Father absence in the monogamous california mouse impairs social behavior and modifies dopamine and glutamate synapses in the medial prefrontal cortex

scientific article published on 4 December 2013

Franco Fraschini, MD, PhD (1932-2020)

scientific article published on 19 October 2020

Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus.

scientific article

Growth hormone response to growth hormone-releasing hormone in early abstinent alcoholic patients

scientific article published on 01 January 1993

Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine

scientific article published on 30 November 2020

High frequency stimulation of the anterior vermis modulates behavioural response to chronic stress: involvement of the prefrontal cortex and dorsal raphe?

scientific article published on 02 May 2018

Lurasidone and Mood Stabilizers in Treatment-Resistant Unipolar Depression: A Case Report Study

scientific article published on 26 January 2017

Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission

scientific article

Male inmate profiles and their biological correlates

scientific article

Melancholic-Like behaviors and circadian neurobiological abnormalities in melatonin MT1 receptor knockout mice.

scientific article published on 31 January 2015

Melatonin MT1 receptor as a novel target in neuropsychopharmacology: MT1 ligands, pathophysiological and therapeutic implications, and perspectives

scientific article published on 25 April 2019

Melatonin, selective and non-selective MT1/MT2 receptors agonists: differential effects on the 24-h vigilance states

scientific article published on 7 January 2014

Mirtazapine and paroxetine in major depression: a comparison of monotherapy versus their combination from treatment initiation

scientific article

Monoamine oxidase A gene promoter methylation and transcriptional downregulation in an offender population with antisocial personality disorder

scientific article

Monoaminergic changes in locus coeruleus and dorsal raphe nucleus following noradrenaline depletion.

scientific article

N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands

scientific article published in October 2009

N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands

scientific article

Neurochemical and psychotropic effects of bupropion in healthy male subjects

scientific article

Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function

scientific article

Nociceptive responses in MT2 receptor knockout mice compared to MT1 and double MT1 /MT2 receptor knockout mice

scientific article published on 19 May 2020

PM361. The hallucinogen D-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors

scientific article published on 27 May 2016

PT628. First in class melatonin MT2 receptors agonists for neuropathic pain.

scientific article

Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex

scientific article published in November 2009

Practitioner Review: The effects of atypical antipsychotics and mood stabilisers in the treatment of depressive symptoms in paediatric bipolar disorder.

scientific article published on 5 May 2017

Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway

scientific article

Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand

scientific journal article

Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study.

scientific article

Quetiapine in Postpartum Psychosis

scientific article published on 01 December 2014

Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide.

scientific article published on 23 April 2018

Role of palmitoylethanolamide (PEA) in depression: Translational evidence

Schizophrenia and serious violence: A clinical-profile analysis incorporating impulsivity and substance-use disorders

scientific article published on 26 March 2011

Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways.

scientific article published on February 2015

Serotonin firing activity as a marker for mood disorders: lessons from knockout mice

scientific article

Serotonin transporter gene promoter methylation in peripheral cells in healthy adults: Neural correlates and tissue specificity

scientific article published on 31 July 2017

Short-Term Natural Course of Depressive Symptoms and Family-Related Stress in Adolescents After Separation From Father

scientific article

Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle.

scientific article

Sleep well. Untangling the role of melatonin MT1 and MT2 receptors in sleep

scientific article published on 21 January 2019

Sleep-wake characterization of double MT₁/MT₂ receptor knockout mice and comparison with MT₁ and MT₂ receptor knockout mice

scientific article published on 16 January 2013

Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex

scientific article published on 22 February 2006

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

scientific article

Targeting melatonin MT2 receptors: A novel pharmacological avenue for inflammatory and neuropathic pain.

scientific article published on 8 February 2017

The cannabinoid CB1receptor and the endocannabinoid anandamide: possible antidepressant targets

scientific article published on 01 November 2008

The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus

scientific article published on 18 December 2015

The hallucinogen d-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors

scientific article (publication date: November 2016)

The psychopharmacology of aggressive behavior: a translational approach: part 1: neurobiology

scientific article published on February 2012

The psychopharmacology of aggressive behavior: a translational approach: part 2: clinical studies using atypical antipsychotics, anticonvulsants, and lithium

scientific article published on April 2012

The selective neuropeptide Y Y5 agonist [cPP(1-7),NPY(19-23),Ala31,Aib32,Gln34]hPP differently modulates emotional processes and body weight in the rat.

scientific article

The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants

scientific article published on 03 September 2009

Trace elements among a sample of prisoners with mental and personality disorders and aggression: correlation with impulsivity and ADHD indices

scientific article published on 05 October 2018

Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.

scientific article

Tryptophan via serotonin/kynurenine pathways abnormalities in a large cohort of aggressive inmates: markers for aggression

scientific article published on 23 April 2016

Unusually mild tuberous sclerosis phenotype is associated withTSC2R905Q mutation

scientific article published on 01 November 2006

Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology

scientific article published on January 2014

Valproate augmentation in a subgroup of patients with treatment-resistant unipolar depression

scientific article

d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology.

scientific article

List of works by Gabriella Gobbi

Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood.

Alterations of the thalamo-cortical system in rats prenatally exposed to ethanol are prevented by concurrent administration of acetyl- l-carnitine

An index of 5-HT synthesis changes during early antidepressant treatment: alpha-[11C]methyl-L-tryptophan PET study

Anatomical and cellular localization of melatonin MT1 and MT2 receptors in the adult rat brain

Antidepressant combination versus antidepressants plus second-generation antipsychotic augmentation in treatment-resistant unipolar depression

Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis

Antinociceptive properties of selective MT(2) melatonin receptor partial agonists

Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam

Brain TRPV1: a depressing TR(i)P down memory lane?

Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

Cannabinoids and emotionality: a neuroanatomical perspective.

Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex.

Characterization of serotonin neurotransmission in knockout mice: implications for major depression

Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission

Chronic nandrolone decanoate exposure during adolescence affects emotional behavior and monoaminergic neurotransmission in adulthood

Clonidine fails to modify dopaminergic neuronal activity during morphine withdrawal

Clozapine blocks dopamine, 5-HT2 and 5-HT3 responses in the medial prefrontal cortex: an in vivo microiontophoretic study.

Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

Differential Function of Melatonin MT and MT Receptors in REM and NREM Sleep

Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery.

Dysfunction of serotonergic activity and emotional responses across the light-dark cycle in mice lacking MT2 receptors

Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission

Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs

Effects of quetiapine and olanzapine in patients with psychosis and violent behavior: a pilot randomized, open-label, comparative study

Efficacy of Topiramate, Valproate, and Their Combination on Aggression/Agitation Behavior in Patients With Psychosis

Electrophysiological characterization of dopamine neuronal activity in the ventral tegmental area across the light-dark cycle

Endocannabinoids in the treatment of mood disorders: evidence from animal models

Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review

Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice

Father absence in the monogamous california mouse impairs social behavior and modifies dopamine and glutamate synapses in the medial prefrontal cortex

Franco Fraschini, MD, PhD (1932-2020)

Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus.

Growth hormone response to growth hormone-releasing hormone in early abstinent alcoholic patients

Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine

High frequency stimulation of the anterior vermis modulates behavioural response to chronic stress: involvement of the prefrontal cortex and dorsal raphe?

Lurasidone and Mood Stabilizers in Treatment-Resistant Unipolar Depression: A Case Report Study

Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission

Male inmate profiles and their biological correlates

Melancholic-Like behaviors and circadian neurobiological abnormalities in melatonin MT1 receptor knockout mice.

Melatonin MT1 receptor as a novel target in neuropsychopharmacology: MT1 ligands, pathophysiological and therapeutic implications, and perspectives

Melatonin, selective and non-selective MT1/MT2 receptors agonists: differential effects on the 24-h vigilance states

Mirtazapine and paroxetine in major depression: a comparison of monotherapy versus their combination from treatment initiation

Monoamine oxidase A gene promoter methylation and transcriptional downregulation in an offender population with antisocial personality disorder

Monoaminergic changes in locus coeruleus and dorsal raphe nucleus following noradrenaline depletion.

N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands

N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands

Neurochemical and psychotropic effects of bupropion in healthy male subjects

Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function

Nociceptive responses in MT2 receptor knockout mice compared to MT1 and double MT1 /MT2 receptor knockout mice

PM361. The hallucinogen D-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors

PT628. First in class melatonin MT2 receptors agonists for neuropathic pain.

Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex

Practitioner Review: The effects of atypical antipsychotics and mood stabilisers in the treatment of depressive symptoms in paediatric bipolar disorder.

Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway

Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand

Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study.

Quetiapine in Postpartum Psychosis

Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide.

Role of palmitoylethanolamide (PEA) in depression: Translational evidence

Schizophrenia and serious violence: A clinical-profile analysis incorporating impulsivity and substance-use disorders

Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways.

Serotonin firing activity as a marker for mood disorders: lessons from knockout mice

Serotonin transporter gene promoter methylation in peripheral cells in healthy adults: Neural correlates and tissue specificity

Short-Term Natural Course of Depressive Symptoms and Family-Related Stress in Adolescents After Separation From Father

Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle.

Sleep well. Untangling the role of melatonin MT1 and MT2 receptors in sleep

Sleep-wake characterization of double MT₁/MT₂ receptor knockout mice and comparison with MT₁ and MT₂ receptor knockout mice

Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

Targeting melatonin MT2 receptors: A novel pharmacological avenue for inflammatory and neuropathic pain.

The cannabinoid CB1receptor and the endocannabinoid anandamide: possible antidepressant targets

The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus

The hallucinogen d-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors

The psychopharmacology of aggressive behavior: a translational approach: part 1: neurobiology

The psychopharmacology of aggressive behavior: a translational approach: part 2: clinical studies using atypical antipsychotics, anticonvulsants, and lithium

The selective neuropeptide Y Y5 agonist [cPP(1-7),NPY(19-23),Ala31,Aib32,Gln34]hPP differently modulates emotional processes and body weight in the rat.

The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants

Trace elements among a sample of prisoners with mental and personality disorders and aggression: correlation with impulsivity and ADHD indices