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List of works by Motofumi Kumazoe

1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose increases a population of T regulatory cells and inhibits IgE production in ovalbumin-sensitized mice

scientific article

6-Azido-6-deoxy-l-idose as a Hetero-Bifunctional Spacer for the Synthesis of Azido-Containing Chemical Probes.

scientific article

67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis ⬇️

scientific article published on January 25, 2013

67-kDa laminin receptor-dependent protein phosphatase 2A (PP2A) activation elicits melanoma-specific antitumor activity overcoming drug resistance

scientific article

Epigallocatechin-3-O-gallate up-regulates microRNA-let-7b expression by activating 67-kDa laminin receptor signaling in melanoma cells.

scientific article

Equol suppresses inflammatory response and bone erosion due to rheumatoid arthritis in mice

scientific article

FOXO3 is essential for CD44 expression in pancreatic cancer cells.

scientific article published on 28 November 2016

Green Tea Catechin Metabolites Exert Immunoregulatory Effects on CD4(+) T Cell and Natural Killer Cell Activities.

scientific article

Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216.

scientific article

Green tea cultivar 'Benifuuki' potentiates split vaccine-induced immunoglobulin A production.

scientific article published on 3 August 2016

Green tea extract containing a highly absorbent catechin prevents diet-induced lipid metabolism disorder

scientific article published on 25 September 2013

Green tea polyphenol EGCG induces lipid-raft clustering and apoptotic cell death by activating protein kinase Cδ and acid sphingomyelinase through a 67 kDa laminin receptor in multiple myeloma cells.

scientific article published on April 2012

Green tea polyphenol epigallocatechin-O-gallate induces cell death by acid sphingomyelinase activation in chronic myeloid leukemia cells.

scientific article

Hydrogen sulphide donors selectively potentiate a green tea polyphenol EGCG-induced apoptosis of multiple myeloma cells.

scientific article published on 27 July 2017

IL-4 receptor α in non-lipid rafts is the target molecule of strictinin in inhibiting STAT6 activation

scientific article published on 21 June 2014

Isoflavones suppress the expression of the FcεRI high-affinity immunoglobulin E receptor independent of the estrogen receptor.

scientific article

Metabolic profiling-based data-mining for an effective chemical combination to induce apoptosis of cancer cells

scientific article

Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

scientific article published on 12 January 2017

Oxygen partial pressure modulates 67‐kDa laminin receptor expression, leading to altered activity of the green tea polyphenol, EGCG ⬇️

scientific article published on July 31, 2012

PDE3 inhibitor and EGCG combination treatment suppress cancer stem cell properties in pancreatic ductal adenocarcinoma.

scientific article

Phosphodiesterase 5 inhibitor acts as a potent agent sensitizing acute myeloid leukemia cells to 67-kDa laminin receptor-dependent apoptosis

scientific article published in August 2013

SphK1 inhibitor potentiates the anti-cancer effect of EGCG on leukaemia cells

scientific article published on 25 May 2016

Sphingosine Kinase-1 Protects Multiple Myeloma from Apoptosis Driven by Cancer-Specific Inhibition of RTKs.

scientific article published on 11 August 2015

The Combination of Green Tea Extract and Eriodictyol Inhibited High-Fat/High-Sucrose Diet-Induced Cholesterol Upregulation Is Accompanied by Suppression of Cholesterol Synthesis Enzymes

scientific article published in January 2016

The FOXO3/PGC-1β signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma

scientific article

The Synthesis of trans-Flavan-3-ol Gallates by Regioselective Oxidative Etherification and Their Cytotoxicity Mediated by 67 LR.

scientific article published on 13 July 2016

Vardenafil, a clinically available phosphodiesterase inhibitor, potentiates the killing effect of EGCG on CLL cells

scientific article published on 24 September 2014

Vitamin A enhances antitumor effect of a green tea polyphenol on melanoma by upregulating the polyphenol sensing molecule 67-kDa laminin receptor

scientific article

γ-Tocotrienol upregulates aryl hydrocarbon receptor expression and enhances the anticancer effect of baicalein.

scientific article published on 04 April 2016

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