List of works - Jinfang Zhu

A molecular roadmap of reprogramming somatic cells into iPS cells

scientific article published on December 2012

A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival.

scientific article

An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation ⬇️

scientific article (publication date: July 2011)

B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow

scientific article published on 2 February 2016

Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite

scientific article

Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation.

scientific article published on 7 March 2018

CD4 T Helper Cell Subsets and Related Human Immunological Disorders

scientific article published on 28 October 2020

CD4 T cells: fates, functions, and faults

scientific article

CD4+ T cell plasticity-Th2 cells join the crowd.

scientific article

Cloning of a cDNA encoding a nerve growth factor precursor from the Agkistrodon halys Pallas

scientific article published on 01 March 1999

Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

scientific article

Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells.

scientific article published on 23 January 2017

Differentiation of effector CD4 T cell populations (*)

scientific article (publication date: 2010)

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells

scientific journal article

Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

scientific article published on 02 February 2009

Dynamic balance between master transcription factors determines the fates and functions of CD4 T cell and innate lymphoid cell subsets.

scientific article

Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance

scientific article

Erratum: Corrigendum: Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

article

Erratum: Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

scientific article

Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells.

scientific article published on 8 September 2010

Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

scientific article published on 22 September 2013

Foreign antigen-independent memory-phenotype CD4+ T cells: a new player in innate immunity?

scientific article

GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors

scientific article

GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice

scientific article

Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types ⬇️

scientific article published on August 26, 2011

Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells

scientific article

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

scientific article

Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

scientific article

Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.

scientific article

Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation

scientific article published on 01 May 2002

Heterogeneity and plasticity of T helper cells

scientific article

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

scientific article published on 31 January 2019

How are T(H)2-type immune responses initiated and amplified?

scientific article

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

scientific article

IL-4 selectively enhances FcγRIII expression and signaling on mouse mast cells ⬇️

scientific article published on August 1, 2003

Immunologic applications of conditional gene modification technology in the mouse

scientific article

In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production.

scientific article

Individual T helper cells have a quantitative cytokine memory

scientific article

Interleukin 2 plays a central role in Th2 differentiation.

scholarly article

Interleukin-4 elicits apoptosis of developing mast cells via a Stat6-dependent mitochondrial pathway

scientific article

KLF13 sustains thymic memory-like CD8+ T cells in BALB/c mice by regulating IL-4–generating invariant natural killer T cells ⬇️

scientific article published on April 11, 2011

Lipid phosphatases identified by screening a mouse phosphatase shRNA library regulate T-cell differentiation and protein kinase B AKT signaling.

scientific article

Lymphoid tissue inducer-A divergent member of the ILC family.

scientific article published on 13 February 2018

MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1.

scientific article

Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts.

scientific article published in August 2003

Molecular switches for regulating the differentiation of inflammatory and IL-10-producing anti-inflammatory T-helper cells

scientific article published on 20 August 2019

Mysterious ILC2 tissue adaptation

scientific article published on 01 October 2018

Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis.

scientific article published on 17 June 2016

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

scientific article

Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells

scientific article

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

article by Chaido Stathopoulou et al published 21 August 2018 in Immunity

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.

scientific article

Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment.

scientific article

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense.

scientific article

STAT6-Dependent Regulation of Th9 Development ⬇️

scientific article published on December 16, 2011

Seventeen-Year Journey Working With a Master.

scientific article

Small-Molecule RORγt Antagonists: One Stone Kills Two Birds

scientific article published on 28 February 2017

Stat5 activation plays a critical role in Th2 differentiation

scientific article published on 01 November 2003

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

scientific article published on 06 October 2013

T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production

scientific article

TCR signaling fuels T(reg) cell suppressor function

scientific article

TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expression. ⬇️

scientific article published on 08 August 2013

Tet2: breaking down barriers to T cell cytokine expression

scientific article

Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis

scientific article published on March 2017

The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

scientific article (publication date: 25 April 2016)

The positive and negative control actions of PTPase on IL-2 signaling

scientific article published on 01 December 1999

The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination

scientific article published on 17 May 2018

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

scientific article

The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma

scientific journal article

The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells

scientific article

The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation

scientific article

The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses

scientific article published on 04 October 2012

Thpok-independent repression of Runx3 by Gata3 during CD4+ T-cell differentiation in the thymus.

scientific article published on 12 February 2013

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

scientific article published on January 2014

Transcriptional Regulatory Network for the Development of Innate Lymphoid Cells

scientific article

Transcriptional regulation of Th2 cell differentiation.

scientific article

Transcriptional regulators dictate innate lymphoid cell fates

scientific article published on 20 January 2017

Transcriptional regulatory networks for CD4 T cell differentiation

scientific article

Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.

scientific article published in February 2018

Transient T-bet expression functionally specifies a distinct T follicular helper subset

scientific article published on 19 September 2018

miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression

scientific article

List of works by Jinfang Zhu

A molecular roadmap of reprogramming somatic cells into iPS cells

A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival.

An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation ⬇️

B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow

Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite

Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation.

CD4 T Helper Cell Subsets and Related Human Immunological Disorders

CD4 T cells: fates, functions, and faults

CD4+ T cell plasticity-Th2 cells join the crowd.

Cloning of a cDNA encoding a nerve growth factor precursor from the Agkistrodon halys Pallas

Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells.

Differentiation of effector CD4 T cell populations (*)

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells

Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

Dynamic balance between master transcription factors determines the fates and functions of CD4 T cell and innate lymphoid cell subsets.

Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance

Erratum: Corrigendum: Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

Erratum: Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells.

Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

Foreign antigen-independent memory-phenotype CD4+ T cells: a new player in innate immunity?

GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors

GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice

Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types ⬇️

Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.

Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation

Heterogeneity and plasticity of T helper cells

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

How are T(H)2-type immune responses initiated and amplified?

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

IL-4 selectively enhances FcγRIII expression and signaling on mouse mast cells ⬇️

Immunologic applications of conditional gene modification technology in the mouse

In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production.

Individual T helper cells have a quantitative cytokine memory

Interleukin 2 plays a central role in Th2 differentiation.

Interleukin-4 elicits apoptosis of developing mast cells via a Stat6-dependent mitochondrial pathway

KLF13 sustains thymic memory-like CD8+ T cells in BALB/c mice by regulating IL-4–generating invariant natural killer T cells ⬇️

Lipid phosphatases identified by screening a mouse phosphatase shRNA library regulate T-cell differentiation and protein kinase B AKT signaling.

Lymphoid tissue inducer-A divergent member of the ILC family.

MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1.

Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts.

Molecular switches for regulating the differentiation of inflammatory and IL-10-producing anti-inflammatory T-helper cells

Mysterious ILC2 tissue adaptation

Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis.

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.

Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment.

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense.

STAT6-Dependent Regulation of Th9 Development ⬇️

Seventeen-Year Journey Working With a Master.

Small-Molecule RORγt Antagonists: One Stone Kills Two Birds

Stat5 activation plays a critical role in Th2 differentiation

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production

TCR signaling fuels T(reg) cell suppressor function

TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expression. ⬇️

Tet2: breaking down barriers to T cell cytokine expression

Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis

The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation

The positive and negative control actions of PTPase on IL-2 signaling

The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma

The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells

The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation

The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses

Thpok-independent repression of Runx3 by Gata3 during CD4+ T-cell differentiation in the thymus.

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

Transcriptional Regulatory Network for the Development of Innate Lymphoid Cells

Transcriptional regulation of Th2 cell differentiation.

Transcriptional regulators dictate innate lymphoid cell fates

Transcriptional regulatory networks for CD4 T cell differentiation

Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.