List of works - Casey T. Weaver

A distal conserved sequence element controls Ifng gene expression by T cells and NK cells.

scientific article

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells

scientific article

Antigen and lipopolysaccharide play synergistic roles in the effector phase of airway inflammation in mice

scientific article

Autoimmunity: increasing suspects in the CD4+ T cell lineup

scientific article published on 17 December 2009

B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice

scientific article published on 9 December 2011

Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection

scientific article published on 17 May 2018

Bioluminescence-based visualization of CD4 T cell dynamics using a T lineage-specific luciferase transgenic model

scientific article published on 3 August 2009

Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1

scientific article

Context is key in the gut

scientific article published in Nature

Daughter's Tolerance of Mom Matters in Mate Choice.

scientific article

Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus.

scientific article published on 28 October 2011

Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene

scientific article published on 01 June 2003

Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription

scientific article published on 9 January 2014

Development and survival of Th17 cells within the intestines: the influence of microbiome- and diet-derived signals

scientific article

Development of dermatitis in CD18-deficient PL/J mice is not dependent on bacterial flora, and requires both CD4+ and CD8+ T lymphocytes

scientific article

Developmental plasticity of Th17 and Treg cells.

scientific article published on 11 June 2009

Developmental regulation of Th17-cell capacity in human neonates

scientific article published on 19 December 2011

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.

scientific article

Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation.

scientific article published on December 2008

Dwelling on T cell fate decisions

scientific article published in May 2013

Early Upregulation of T Cell IL-10 Production Plays an Important Role in Oral Tolerance Induction

article

Editorial overview: lymphocyte development

scientific article published on 9 April 2009

Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis

scientific article published on 17 November 2008

Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model

scientific article

Emergence of the Th17 pathway and its role in host defense.

scientific article published on January 2008

Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

scientific article

Experimental Models to Study Molecular Mechanisms Underlying Intestinal Inflammation

article

Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness

scientific article published on 6 April 2011

Gene delivery into primary T cells: overview and characterization of a transgenic model for efficient adenoviral transduction.

scientific article

Heterogeneity of single cell cytokine gene expression in clonal T cell populations ⬇️

scientific article published on October 1, 1994

IFN-gamma-inducible chemokines enhance adaptive immunity and colitis

scientific article published on 01 October 2003

IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance

scientific article

IL-2 coordinates IL-2-producing and regulatory T cell interplay.

scientific article

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis.

scientific article published on 18 June 2013

IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism.

scientific article published on 14 June 2013

IL-9 as a mediator of Th17-driven inflammatory disease

scientific article published on 13 July 2009

Imaging CD8+ T cell dynamics in vivo using a transgenic luciferase reporter

scientific article published on 14 August 2007

Immunology. T-bet or not T-bet

scientific article published on 01 November 2003

Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination

scientific article published on 12 June 2015

Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis.

scientific article

Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function

scientific article published on 01 September 1999

Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective.

scientific article published on December 2009

Intestinal effector T cells in health and disease.

scientific article published on September 2009

Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.

scientific article published on 14 April 2015

Lineage-specific Effects of 1,25-Dihydroxyvitamin D3 on the Development of Effector CD4 T Cells ⬇️

scientific article published on November 3, 2010

Linking vitamin d deficiency to inflammatory bowel disease

scientific article

MMP induced by Gr-1+ cells are crucial for recruitment of Th cells into the airways.

scientific article published on August 2009

Membrane IL-1: a key protein in antigen presentation

scientific article published on 01 May 1987

Memory CD4 T cells emerge from effector T-cell progenitors

scientific article published on 5 March 2008

Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR.

scientific article published in August 1999

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli

scientific article published on July 2010

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

scientific article

Narcissistic helpers

scientific article published in Nature

Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

scientific article published on 13 December 2011

Neutrophils produce interleukin 17A (IL-17A) in a dectin-1- and IL-23-dependent manner during invasive fungal infection.

scientific article published on August 2011

New developments in experimental models of inflammatory bowel disease.

scientific article

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals.

scientific article published on July 2013

One road to the TH17 pathway: how TH1 led to TH17 (and vice versa), and first came last

scientific article published on 02 July 2020

Oral-antigen delivery by way of a multiple emulsion system enhances oral tolerance.

scientific article

PD-L1hi B cells are critical regulators of humoral immunity.

scientific article published on 22 January 2015

Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice

scientific article published on 05 August 2013

Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation

scientific article

Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis

scientific article published on 07 November 2019

Reciprocal interactions of the intestinal microbiota and immune system.

scientific article

Regional differences in L-selectin expression in murine intestinal lymphocytes☆☆☆

article

Regulation of the Ifng locus in the context of T-lineage specification and plasticity.

scientific article

Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo

scientific article published on 23 December 2011

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10

scientific article published on 12 August 2007

Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants

scientific article

Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.

scientific article

Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

scientific article

Single-cell analyses of CD4+ T cells from alpha beta T cell receptor-transgenic mice: a distinct mucosal cytokine phenotype in the absence of transgene-specific antigen

scientific article published on 01 July 1997

Stem-cell-like qualities of immune memory; CD4+ T cells join the party.

scientific article published on February 2012

T-cell subsets: the more the merrier

scientific article published on 01 January 2007

TGF-beta promotes Th17 cell development through inhibition of SOCS3.

scientific article

TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity

scientific article published on 01 July 2020

Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis

scientific article published on 18 May 2015

Th17 cells mediate clade-specific, serotype-independent mucosal immunity

scientific article

Th17: The ascent of a new effector T-cell subset. Preface

scientific article published in March 2009

Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria

scientific article published on 29 November 2012

The AP-1 transcription factor Batf controls T(H)17 differentiation

scientific article

The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin ⬇️

scientific article published on November 15, 2012

The Th17 family: flexibility follows function.

scientific article published on March 2013

The central role of the Th17 lineage in regulating the inflammatory/autoimmune axis

scientific article published on 01 December 2007

The genetics of inflammatory bowel disease

scientific article published on 01 October 2007

The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells.

scientific article published on 13 February 2014

The β-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22.

scientific article published on 29 August 2012

Transforming growth factor-beta induces development of the T(H)17 lineage

scientific article (publication date: 11 May 2006)

γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response.

scientific article

List of works by Casey T. Weaver

A distal conserved sequence element controls Ifng gene expression by T cells and NK cells.

Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells

Antigen and lipopolysaccharide play synergistic roles in the effector phase of airway inflammation in mice

Autoimmunity: increasing suspects in the CD4+ T cell lineup

B cell-derived IL-10 does not regulate spontaneous systemic autoimmunity in MRL.Fas(lpr) mice

Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection

Bioluminescence-based visualization of CD4 T cell dynamics using a T lineage-specific luciferase transgenic model

Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1

Context is key in the gut

Daughter's Tolerance of Mom Matters in Mate Choice.

Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus.

Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene

Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription

Development and survival of Th17 cells within the intestines: the influence of microbiome- and diet-derived signals

Development of dermatitis in CD18-deficient PL/J mice is not dependent on bacterial flora, and requires both CD4+ and CD8+ T lymphocytes

Developmental plasticity of Th17 and Treg cells.

Developmental regulation of Th17-cell capacity in human neonates

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.

Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation.

Dwelling on T cell fate decisions

Early Upregulation of T Cell IL-10 Production Plays an Important Role in Oral Tolerance Induction

Editorial overview: lymphocyte development

Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis

Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model

Emergence of the Th17 pathway and its role in host defense.

Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

Experimental Models to Study Molecular Mechanisms Underlying Intestinal Inflammation

Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness

Gene delivery into primary T cells: overview and characterization of a transgenic model for efficient adenoviral transduction.

Heterogeneity of single cell cytokine gene expression in clonal T cell populations ⬇️

IFN-gamma-inducible chemokines enhance adaptive immunity and colitis

IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance

IL-2 coordinates IL-2-producing and regulatory T cell interplay.

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis.

IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism.

IL-9 as a mediator of Th17-driven inflammatory disease

Imaging CD8+ T cell dynamics in vivo using a transgenic luciferase reporter

Immunology. T-bet or not T-bet

Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination

Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis.

Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function

Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective.

Intestinal effector T cells in health and disease.

Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.

Lineage-specific Effects of 1,25-Dihydroxyvitamin D3 on the Development of Effector CD4 T Cells ⬇️

Linking vitamin d deficiency to inflammatory bowel disease

MMP induced by Gr-1+ cells are crucial for recruitment of Th cells into the airways.

Membrane IL-1: a key protein in antigen presentation

Memory CD4 T cells emerge from effector T-cell progenitors

Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR.

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

Narcissistic helpers

Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

Neutrophils produce interleukin 17A (IL-17A) in a dectin-1- and IL-23-dependent manner during invasive fungal infection.

New developments in experimental models of inflammatory bowel disease.

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals.

One road to the TH17 pathway: how TH1 led to TH17 (and vice versa), and first came last

Oral-antigen delivery by way of a multiple emulsion system enhances oral tolerance.

PD-L1hi B cells are critical regulators of humoral immunity.

Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice

Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation

Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis

Reciprocal interactions of the intestinal microbiota and immune system.

Regional differences in L-selectin expression in murine intestinal lymphocytes☆☆☆

Regulation of the Ifng locus in the context of T-lineage specification and plasticity.

Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo

Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10

Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants

Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.

Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

Single-cell analyses of CD4+ T cells from alpha beta T cell receptor-transgenic mice: a distinct mucosal cytokine phenotype in the absence of transgene-specific antigen

Stem-cell-like qualities of immune memory; CD4+ T cells join the party.

T-cell subsets: the more the merrier

TGF-beta promotes Th17 cell development through inhibition of SOCS3.

TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity

Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis

Th17 cells mediate clade-specific, serotype-independent mucosal immunity

Th17: The ascent of a new effector T-cell subset. Preface