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Authors whose works are in public domain in at least one jurisdiction

List of works by Donald S Kirkpatrick

A Biologist's Field Guide to Multiplexed Quantitative Proteomics

scientific article published on 12 February 2016

A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway

scientific article published on 3 February 2013

A Perturbed Ubiquitin Landscape Distinguishes Between Ubiquitin in Trafficking and in Proteolysis ⬇️

scientific article published on March 22, 2011

A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation.

scientific article

A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834

scientific article published on 6 April 2015

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

scientific article published on 29 January 2012

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis.

scientific article published on 28 December 2015

Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions.

scientific article

Chaperone mediated detection of small molecule target binding in cells

scientific article published on 23 January 2020

Characterizing ubiquitination sites by peptide-based immunoaffinity enrichment.

scientific article

Complementary proteomic tools for the dissection of apoptotic proteolysis events.

scientific article published on 29 March 2012

Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling

scientific article

Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death.

scientific article

Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry

scientific article

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

scientific journal article

Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies

scientific article published on 10 December 2015

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling

scientific article published in February 2018

Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration

scientific article published on 28 October 2013

Engineering and Structural Characterization of a Linear Polyubiquitin-Specific Antibody ⬇️

scientific article published on December 29, 2011

Extended ubiquitin species are protein-based DUB inhibitors

scientific article published on 6 July 2014

Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.

scientific article

GPS navigation of the protein-stability landscape

scientific article published on 01 January 2009

Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics

scientific article published on 03 February 2020

HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.

scientific article published on 31 December 2012

Immunoaffinity enrichment coupled to quantitative mass spectrometry reveals ubiquitin-mediated signaling events

scientific article

Loss of the tumor suppressor BAP1 causes myeloid transformation

scientific article published on 09 August 2012

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

scientific article published on November 2007

Modulation of K11-linkage formation by variable loop residues within UbcH5A

scientific article

Monitoring protein communities and their responses to therapeutics

scientific article published on 05 March 2020

Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome.

scientific article

NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.

scientific article published on 30 June 2016

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

scientific article

OTULIN limits cell death and inflammation by deubiquitinating LUBAC

scientific article published in Nature

Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

scientific article published on September 2014

PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes.

scientific article

PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity.

scientific article

Peptide level immunoaffinity enrichment enhances ubiquitination site identification on individual proteins

scientific article published on 18 October 2013

Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition

scientific article

Preparation of distinct ubiquitin chain reagents of high purity and yield

scientific article

Proteomic insights into ubiquitin and ubiquitin-like proteins.

scientific article

Publisher Correction: Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics

scientific article published on 26 February 2020

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

article

Quantitative phosphoproteomic analysis of the PI3K-regulated signaling network.

scientific article published on 10 June 2016

Ribosome binding of a single copy of the SecY complex: implications for protein translocation

scientific article

Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle

scientific article published on 27 June 2017

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling.

scientific article

Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations

scientific article published in December 2012

The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications

scientific article

The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking

scientific article published on 4 March 2008

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

scientific article

Transcription factor Etv5 is essential for the maintenance of alveolar type II cells

scientific article

USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria

scientific article

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.

scientific article published on 21 September 2017

Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling

scientific article

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

scientific article

Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities.

scientific article

Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling

scientific article (publication date: 2011)

Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment

scientific article

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

scientific article published on 26 November 2010

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