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List of works by Michael C. Phillips

A comparison of the interfacial interactions of the apoprotein from high density lipoprotein and β-casein with phospholipids

scientific article published on October 17, 1975

A comparison of the surface activities of human apolipoproteins A-I and A-II at the air/water interface

scientific article published on 01 April 1988

A comparison of the surface activities of rat plasma apolipoproteins C-II, C-III-0, C-III-3

scientific article published on 01 May 1983

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state.

scientific article published on 13 November 2017

A quantitative analysis of apolipoprotein binding to SR-BI: multiple binding sites for lipid-free and lipid-associated apolipoproteins

scientific article published on 01 April 2003

A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol

scientific article published on 27 September 2011

A technique to estimate the apparent surface pressure of emulsion particles using apolipoproteins as probes

scientific article published on 01 September 1992

ABCA1-induced cell surface binding sites for ApoA-I.

scientific article published on 3 May 2007

Alpha-helix formation is required for high affinity binding of human apolipoprotein A-I to lipids

scientific article published on 12 March 2004

Apolipoprotein A-I helical structure and stability in discoidal high-density lipoprotein (HDL) particles by hydrogen exchange and mass spectrometry.

scientific article

Apolipoprotein B-100 conformation and particle surface charge in human LDL subspecies: implication for LDL receptor interaction

scientific article published on 01 September 1998

Apolipoprotein E isoforms and lipoprotein metabolism

scientific article

Apolipoprotein-mediated plasma membrane microsolubilization. Role of lipid affinity and membrane penetration in the efflux of cellular cholesterol and phospholipid

scientific article published on 01 January 1999

Aromatic residue position on the nonpolar face of class a amphipathic helical peptides determines biological activity

scientific article published on 8 April 2004

Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic alpha-helix as a recognition motif

scientific article published on 01 June 2000

Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening

scientific article published on 25 October 2012

Cellular cholesterol efflux mediated by cyclodextrins

scientific article published on July 1995

Cellular cholesterol efflux mediated by cyclodextrins. Demonstration Of kinetic pools and mechanism of efflux.

scientific article published on July 1996

Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apoA-I.

scientific article published on 5 February 2008

Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I.

scientific article published on 17 January 2006

Characterization of the heparin binding sites in human apolipoprotein E.

scientific article published on 14 February 2003

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport

scientific article

Cholesterol transfer from small and large unilamellar vesicles

scientific article published on 01 September 1984

Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol.

scientific article

Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry.

scientific article published on 10 April 2013

Comparison of the effects of inorganic and organic (hydrophobic) cations on the physical states of proteins and phospholipid bilayer membranes

scientific article published on August 15, 1977

Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism.

scientific article published on September 2002

Complex and cluster formation in mixed lecithincholesterol bilayers. Cooperativity of motion in lipid systems

scientific article published on 01 November 1971

Conformation of the lecithin polar group in charged vesicles

scientific article published in Nature

Conformational flexibility of the N-terminal domain of apolipoprotein a-I bound to spherical lipid particles

scientific article published on 2 October 2008

Contributions of domain structure and lipid interaction to the functionality of exchangeable human apolipoproteins.

scientific article

Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of apolipoprotein A-I.

scientific article published in August 2006

Contributions of the carboxyl-terminal helical segment to the self-association and lipoprotein preferences of human apolipoprotein E3 and E4 isoforms

scientific article published on 18 January 2008

Cytoskeleton disruption in J774 macrophages: consequences for lipid droplet formation and cholesterol flux

scientific article published on 8 October 2011

Differences between conformations of lecithin and phosphatidylethanolamine polar groups and their effects on interactions of phospholipid bilayer membranes

scientific article published on 01 December 1972

Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain

scientific article published in September 2000

Differences in the interaction of inorganic and organic (hydrophobic) cations with phosphatidylserine membranes

scientific article published on December 16, 1975

Domain structure and lipid interaction in human apolipoproteins A-I and E, a general model

scientific article published on 22 April 2003

Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4.

scientific article published in April 2006

Effect of substrate physical state on the activity of acid cholesteryl ester hydrolase

scientific article published on February 1990

Effect of the arrangement of tandem repeating units of class A amphipathic alpha-helixes on lipid interaction

scientific article published on 01 January 1995

Effect of the cholesterol content of reconstituted LpA-I on lecithin:cholesterol acyltransferase activity

scientific article published on 01 March 1995

Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux

scientific article published on 30 September 2008

Effects of acceptor particle size on the efflux of cellular free cholesterol

scientific article published on July 1995

Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function

scientific article published on 19 March 2007

Effects of apolipoprotein A-I on ATP-binding cassette transporter A1-mediated efflux of macrophage phospholipid and cholesterol: formation of nascent high density lipoprotein particles

scientific article published on 19 August 2003

Effects of apolipoprotein structure on the kinetics of apolipoprotein transfer between phospholipid vesicles

scientific article published in January 1991

Effects of cholesterol and lipoproteins on endocytosis by a monocyte-like cell line

scientific article published on December 1986

Effects of enrichment of fibroblasts with unesterified cholesterol on the efflux of cellular lipids to apolipoprotein A-I.

scientific article published on 22 January 2002

Effects of membrane lipid composition on the kinetics of cholesterol exchange between lipoproteins and different species of red blood cells

scientific article published in August 1990

Effects of membrane lipids and -proteins and cytoskeletal proteins on the kinetics of cholesterol exchange between high density lipoprotein and human red blood cells, ghosts and microvesicles

scientific article

Effects of polymorphism on the lipid interaction of human apolipoprotein E.

scientific article published on 12 August 2003

Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry

scientific article published on 24 October 2012

Effects of the core lipid on the energetics of binding of ApoA-I to model lipoprotein particles of different sizes

scientific article published in August 2005

Effects of the neutral lipid content of high density lipoprotein on apolipoprotein A-I structure and particle stability

scientific article published on 01 November 1995

Efflux of Cholesterol from Different Cellular Pools†

scientific article published on 01 April 2000

Efflux of newly synthesized cholesterol and biosynthetic sterol intermediates from cells. Dependence on acceptor type and on enrichment of cells with cholesterol

scientific article

Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4.

scientific article published on 3 July 2012

Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4.

scientific article published on December 2014

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

scientific article

Helix orientation of the functional domains in apolipoprotein e in discoidal high density lipoprotein particles

scientific article

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

scientific article

High-density lipoprotein heterogeneity and function in reverse cholesterol transport

scientific article published on June 2010

Hydrolysis of lipid monolayers and the substrate specificity of hepatic lipase

scientific article published on 01 April 1986

Hydrophobic free energy and the denaturation of proteins.

scientific article published in November 1977

Identification of a receptor mediating absorption of dietary cholesterol in the intestine

scientific article published on 01 December 1998

Identification of an apolipoprotein A-I structural element that mediates cellular cholesterol efflux and stabilizes ATP binding cassette transporter A1.

scientific article published on 29 March 2004

Importance of different pathways of cellular cholesterol efflux

scientific article published on 23 January 2003

Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids

scientific article published on 21 September 2004

Influence of Apolipoprotein (Apo) A-I Structure on Nascent High Density Lipoprotein (HDL) Particle Size Distribution

scientific article published on August 2, 2010

Influence of C-terminal α-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality.

scientific article

Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I.

scientific article published on 30 October 2010

Influence of apoE domain structure and polymorphism on the kinetics of phospholipid vesicle solubilization

scientific article published on 01 October 2002

Influence of apolipoprotein A-I and apolipoprotein A-II availability on nascent HDL heterogeneity

scientific article published on October 2013

Influence of apolipoprotein A-I domain structure on macrophage reverse cholesterol transport in mice

scientific article published on 11 November 2010

Influence of cholesterol on bilayers of ester- and ether-linked phospholipids. Permeability and 13C-nuclear magnetic resonance measurements

scientific article published on 01 May 1984

Influence of domain stability on the properties of human apolipoprotein E3 and E4 and mouse apolipoprotein E.

scientific article

Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I.

scientific article

Interaction between the 35 kDa apolipoprotein of pulmonary surfactant and saturated phosphatidylcholines. Effects of temperature

scientific article published on October 1986

Interaction between the N- and C-terminal domains modulates the stability and lipid binding of apolipoprotein A-I.

scientific article published on March 2009

Interaction of Apoprotein from Porcine High-Density Lipoprotein with Dimyristoyl Lecithin. 2. Nature of Lipid-Protein Interaction

scientific article published on May 1, 1976

Interaction of Thioflavin T with amyloid fibrils of apolipoprotein A-I N-terminal fragment: Resonance energy transfer study

scientific article published on 15 November 2013

Interactions of apolipoprotein A-I with high-density lipoprotein particles

scientific article published on 4 March 2013

Intestinal sterol absorption mediated by scavenger receptors is competitively inhibited by amphipathic peptides and proteins

scientific article published on 01 October 2000

Ion-Binding to Phospholipids. Interaction of Calcium and Lanthanide Ions with Phosphatidylcholine (Lecithin)

scientific article published on October 1, 1975

Ion-Binding to Phospholipids. Interaction of Calcium with Phosphatidylserine

scientific article published on February 16, 1976

Is ABCA1 a Lipid Transfer Protein?

scientific article published on 5 January 2018

Kinetic and thermodynamic analyses of spontaneous exchange between high-density lipoprotein-bound and lipid-free apolipoprotein A-I.

scientific article

Kinetics and mechanism of exchange of apolipoprotein C-III molecules from very low density lipoprotein particles

scientific article published in March 1999

Lateral compressibility and penetration into phospholipid monolayers and bilayer membranes

scientific article published in Nature

Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles

scientific article published on 30 August 2001

Location and motion of free cholesterol molecules in high density lipoprotein

scientific article published on 01 June 1981

Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano

scientific article published on 6 August 2009

Mechanisms and consequences of cellular cholesterol exchange and transfer.

scientific article published on June 1987

Mechanisms of high density lipoprotein-mediated efflux of cholesterol from cell plasma membranes

scientific article published in April 1998

Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4.

scientific article published on 3 December 2010

Molecular determinants of plasma cholesteryl ester transfer protein binding to high density lipoproteins.

scientific article published on May 1995

Molecular interactions in mixed lecithin systems

scientific article published on 01 January 1970

Molecular mechanism of apolipoprotein E binding to lipoprotein particles

scientific article published on April 2009

Molecular mechanisms of cellular cholesterol efflux

scientific article

Molecular mechanisms responsible for the differential effects of apoE3 and apoE4 on plasma lipoprotein-cholesterol levels.

scientific article published on 14 February 2013

Monolayer characteristics of some 1,2-diacyl, I-alkyl-2-acyl and 1,2-dialkyl phospholipids at the air-water interface.

scientific article

Monolayer characteristics of some glycolipids at the air-water interface.

scientific article published in February 1975

Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane

scientific article published on 23 June 2007

New insights into the heparan sulfate proteoglycan-binding activity of apolipoprotein E.

scientific article

Novel in vivo method for measuring cholesterol mass flux in peripheral macrophages.

scientific article

Nuclear magnetic resonance study of lecithin-cholesterol interactions

scientific article published on January 28, 1972

Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages

scientific article

Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

scientific article published on 4 February 2015

Role of apolipoproteins in cellular cholesterol efflux

scientific article published on 01 February 1986

Role of the N- and C-terminal domains in binding of apolipoprotein E isoforms to heparan sulfate and dermatan sulfate: a surface plasmon resonance study.

scientific article published on June 2008

Role of the plasma membrane in the mechanism of cholesterol efflux from cells

scientific article published on 01 November 1984

Scavenger Receptor Class B Type I as a Mediator of Cellular Cholesterol Efflux to Lipoproteins and Phospholipid Acceptors

scientific article published on March 6, 1998

Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.

scientific article

Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux

scientific article published on 01 August 1997

Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure

scientific article

Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor

scientific article published on 19 September 2001

Serum albumin acts as a shuttle to enhance cholesterol efflux from cells.

scientific article published on 3 January 2013

Structural analysis of lipoprotein E particles

scientific article

Structural and functional consequences of the Milano mutation (R173C) in human apolipoprotein A-I.

scientific article published on 24 March 2009

Structural and metabolic consequences of liposome-lipoprotein interactions

scientific article published in June 1998

Structural investigations of lipid, polypeptide and protein multilayers.

scientific article

Structure of human apolipoprotein A-IV: a distinct domain architecture among exchangeable apolipoproteins with potential functional implications

scientific article

Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells

scientific article published on 25 May 2007

Studies of synthetic peptides of human apolipoprotein A-I containing tandem amphipathic alpha-helixes.

scientific article

The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins

scientific article

The conformation of apolipoprotein E isoforms in phospholipid complexes and their interaction with human Hep G2 cells

scientific article published on 01 August 1984

The contribution of alpha-helices to the surface activities of proteins

scientific article published on 01 October 1984

The effect of high density lipoprotein phospholipid acyl chain composition on the efflux of cellular free cholesterol.

scientific article published on March 1995

The helical hydrophobic moments and surface activities of serum apolipoproteins

scientific article published on 01 November 1983

The inter- and intra-molecular mixing of hydrocarbon chains in lecithin-water systems

scientific article published on 01 March 1972

The interaction of cholesterol with the sterol free lipids of plasma membranes

scientific article published in August 1970

The interaction of ions with phosphatidylcholine.

scientific article published in August 1977

The physical properties of an effective lung surfactant

scientific article published on 01 June 1979

The roles of C-terminal helices of human apolipoprotein A-I in formation of high-density lipoprotein particles

scientific article published on 9 October 2013

The roles of different pathways in the release of cholesterol from macrophages.

scientific article published on 29 August 2007

The stoichiometry and dynamics of lecithin-cholesterol clusters in bilayer membranes.

scientific article published in July 1974

The surface properties of apolipoproteins A-I and A-II at the lipid/water interface

scientific article published on 01 August 1989

The uptake of cholesterol at the small-intestinal brush border membrane is inhibited by apolipoproteins

scientific article published on 01 July 1997

Two-step mechanism of binding of apolipoprotein E to heparin: implications for the kinetics of apolipoprotein E-heparan sulfate proteoglycan complex formation on cell surfaces

scientific article published on 6 December 2004

Wild-type ApoA-I and the Milano variant have similar abilities to stimulate cellular lipid mobilization and efflux

scientific article published on 05 July 2007