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List of works by Ilse Vanhorebeek

AKIpredictor, an online prognostic calculator for acute kidney injury in adult critically ill patients: development, validation and comparison to serum neutrophil gelatinase-associated lipocalin

scientific article published on 27 January 2017

Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities

scientific journal article

Achieving enteral nutrition during the acute phase in critically ill children: Associations with patient characteristics and clinical outcome

scientific article published on 16 September 2020

Amino acid concentrations in critically ill children following cardiac surgery*.

scientific article published in May 2014

Amino acid supplements in critically ill patients

scientific article published on 6 December 2017

Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial

scientific article published in 2022

Assessment of quadriceps muscle mass with ultrasound in critically ill patients: intra- and inter-observer agreement and sensitivity

Charisma: an integrated approach to automatic H&E-stained skeletal muscle cell segmentation using supervised learning and novel robust clump splitting.

scientific article published on 13 August 2013

Circulating Levels of the Shed Scavenger Receptor sCD163 and Association with Outcome of Critically Ill Patients

scientific article published on 13 November 2012

Circulating phthalates during critical illness in children are associated with long-term attention deficit: a study of a development and a validation cohort.

scientific article published on 14 December 2015

Continuous Monitoring of Urine Output And Hemodynamic Disturbances Improves Early Detection of Acute Kidney Injury During First Week of Icu Stay.

scientific article published in October 2015

Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study

scientific article published on 13 December 2011

Corrigendum to: 'Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: The Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of

scholarly article published in European Heart Journal

Cortisol Response to Critical Illness: Effect of Intensive Insulin Therapy

article

Cost-effectiveness study of early versus late parenteral nutrition in critically ill children (PEPaNIC): preplanned secondary analysis of a multicentre randomised controlled trial

scientific article published on 15 January 2018

Critical Care Management of Stress-Induced Hyperglycemia

Critical illness-induced dysglycemia and the brain

scientific article

Diabetes of injury: novel insights

scientific article published on December 2006

Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice.

scientific article published on 23 February 2017

Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later

scientific article published in 2021

Dynamics and prognostic value of the hypothalamus-pituitary-adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study

scientific article published on 11 November 2019

Early Supplemental Parenteral Nutrition in Critically Ill Children: An Update

scientific article published on 11 June 2019

Early detection of acute kidney injury during the first week of the ICU.

scientific article

Early hypophosphatemia in critically ill children and the effect of parenteral nutrition: A secondary analysis of the PEPaNIC RCT

scientific article published in 2022

Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits

scientific article published on 6 March 2012

Early versus Late Parenteral Nutrition in Critically Ill Children

scientific article published on 15 March 2016

Early versus Late Parenteral Nutrition in Critically Ill Children

scientific article published on 01 July 2016

Early versus late parenteral nutrition in critically ill, term neonates: a preplanned secondary subgroup analysis of the PEPaNIC multicentre, randomised controlled trial

scientific article published on 11 May 2018

Effect of Intensive Insulin Therapy on the Somatotropic Axis of Critically Ill Children

scientific article published on 01 June 2011

Effect of early parenteral nutrition during paediatric critical illness on DNA methylation as a potential mediator of impaired neurocognitive development: a pre-planned secondary analysis of the PEPaNIC international randomised controlled trial

scientific article published on 19 February 2020

Effect of early supplemental parenteral nutrition in the paediatric ICU: a preplanned observational study of post-randomisation treatments in the PEPaNIC trial.

scientific article published on 15 May 2017

Effect of tight glucose control with insulin on the thyroid axis of critically ill children and its relation with outcome

scientific article

Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial

scientific article published on 10 September 2013

Effects of hyperglycemia and intensive insulin therapy on neurons and glial cells during critical illness

Endocrine aspects of acute and prolonged critical illness

scientific article published on January 2006

Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver

scientific article published on 01 May 2020

FGF21 Response to Critical Illness: Effect of Blood Glucose Control and Relation With Cellular Stress and Survival

scientific article published on 14 August 2015

Fibroblast growth factor 21 response to critical illness: effect of blood glucose control and relation with mitochondrial dysfunction, the integrated stress response and survival.

scientific article published in October 2015

Glucose dysregulation and neurological injury biomarkers in critically ill children

scientific article published on 28 July 2010

Glucose homeostasis, nutrition and infections during critical illness.

scientific article published on 7 January 2017

Glucose, Insulin, and the Kidney

Glycaemic control and perioperative organ protection

scientific article published on March 2008

Glycaemic control in paediatric critical care – Authors' reply

scientific article published in The Lancet

Glycaemic control in trauma patients, is there a role?

Glycemic and nonglycemic effects of insulin: how do they contribute to a better outcome of critical illness?

scientific article

Glycemic control and outcome related to cardiopulmonary bypass

scientific article published on 27 March 2015

Glycemic control modulates arginine and asymmetrical-dimethylarginine levels during critical illness by preserving dimethylarginine-dimethylaminohydrolase activity

scientific article

Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: the Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Soc

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)

article published 13 June 2006 in European Heart Journal

Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: full text: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)

article published 1 June 2007 in European Heart Journal Supplements

HLA-DR Expression on Monocyte Subsets in Critically Ill Children

scientific article

Hormonal and metabolic strategies to attenuate catabolism in critically ill patients

scientific article

Hyperglycemia in the Surgical Intensive Care Unit

Hyperglycemic kidney damage in an animal model of prolonged critical illness.

scientific article

ICU-acquired weakness

scientific article published on 19 February 2020

Impact of early parenteral nutrition on catabolism.

scientific article published on 19 March 2013

Impact of early parenteral nutrition on metabolism and kidney injury

scientific article published on 28 March 2013

Impact of early versus late parenteral nutrition on morphological and molecular markers of atrophy and autophagy in skeletal muscle of critically ill patients

scientific article published in 2013

Impact of hyperglycemia on neuropathological alterations during critical illness.

scientific article published on 22 March 2012

Impact of supplemental parenteral nutrition early during critical illness on invasive fungal infections: a secondary analysis of the EPaNIC randomized controlled trial

scientific article published on 02 June 2018

Impact of withholding early parenteral nutrition completing enteral nutrition in pediatric critically ill patients (PEPaNIC trial): study protocol for a randomized controlled trial

scientific article published on May 2015

Increasing glucose load while maintaining normoglycemia does not evoke neuronal damage in prolonged critically ill rabbits

scientific article

Increasing intravenous glucose load in the presence of normoglycemia: effect on outcome and metabolism in critically ill rabbits

scientific article published in February 2010

Indication and practical use of intensive insulin therapy in the critically ill.

scientific article published on August 2007

Insufficient activation of autophagy allows accumulation of cellular damage and may contribute to sustained organ failure in prolonged critically ill patients

scientific article published on 11 March 2011

Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients

scientific article published on 26 January 2011

Insufficient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness

scientific article published in January 2013

Insufficient autophagy relates to mitochondrial dysfunction, organ failure and adverse outcome in an animal model of critical illness.

scientific article published on 20 March 2012

Insulin treatment in intensive care patients

scientific article

Insulin, glucose control and multiple organ dysfunction syndrome

Intensive insulin therapy and brief hypoglycemia do not increase neurological injury markers in critically ill children

scientific article published in March 2010

Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study

scientific article published on 26 January 2009

Intensive insulin therapy in critically ill children: impact on blood glucose dynamics and its relation with mortality

Intensive insulin therapy in high-risk cardiac surgery patients: evidence from the Leuven randomized study

scientific article published on January 2006

Intensive insulin therapy in the intensive care unit

scientific article

Intensive insulin therapy in the intensive care unit: update on clinical impact and mechanisms of action

scientific article published on July 2006

Intensive insulin therapy protects the endothelium of critically ill patients

scientific article

Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model

scientific article published on May 2001

Lectin pathway of complement activation and relation with clinical complications in critically ill children

scientific article published on 15 October 2013

Leukocyte telomere length in paediatric critical illness: effect of early parenteral nutrition

scientific article published on 21 February 2018

Long-term developmental effects of withholding parenteral nutrition for 1 week in the paediatric intensive care unit: a 2-year follow-up of the PEPaNIC international, randomised, controlled trial

scientific article published on 14 September 2018

Metabolic aspects of critical illness polyneuromyopathy

scientific article published on October 2009

Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation

scientific article published on 20 November 2014

Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)

scientific article

Mitochondrial and endoplasmic reticulum dysfunction and related defense mechanisms in critical illness-induced multiple organ failure

scientific article published on 17 February 2017

Mitochondrial fusion, fission, and biogenesis in prolonged critically ill patients

scientific article published on 19 October 2011

Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?

Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?

Modulation of regional nitric oxide metabolism: blood glucose control or insulin?

scientific article published on 22 April 2008

Molecular mechanisms behind clinical benefits of intensive insulin therapy during critical illness: glucose versus insulin

scientific article published on December 2009

Monitoring enteral nutrition efficacy in ICU patients: is there a place for the Brix value-derived fraction of enteral formula in gastric residual volume?

scientific article published in March 2010

Muscle atrophy and preferential loss of myosin in prolonged critically ill patients

scientific article published in January 2012

Neurocognition after paediatric heart surgery: a systematic review and meta-analysis

scientific article

Neurocognitive consequences of iatrogenicphthalate exposure during critical illness in children: a study of a development and validation cohort.

scientific article

Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial

scientific article published on October 2012

Neuropathological Correlates of Hyperglycemia During Prolonged Polymicrobial Sepsis in Mice

scientific article published on 22 May 2015

Non-Thyroidal Illness Syndrome in Critically Ill Children: Prognostic Value and Impact of Nutritional Management

scientific article published on 11 March 2019

Performance of Pediatric Mortality Prediction Scores for PICU Mortality and 90-Day Mortality

scientific article published on 01 February 2019

Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?

scientific article published in 2022

Phthalate and alternative plasticizers in indwelling medical devices in pediatric intensive care units

scientific article published on 01 October 2018

Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit*

article

Predictive value for weakness and 1-year mortality of screening electrophysiology tests in the ICU.

scientific article published on 13 August 2015

Predictive value for weakness and 1-year mortality of screening electrophysiology tests in the ICU.

scientific article

Premorbid obesity, but not nutrition, prevents critical illness-induced muscle wasting and weakness.

scientific article published on 20 July 2016

Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients

scientific article published in January 2005

Receptor for advanced glycation end products axis in critically ill patients

scientific article published on 17 March 2014

Reduced cortisol metabolism drives hypercortisolism in critical illness.

scientific article published on 20 March 2012

Reduced cortisol metabolism during critical illness

scientific article published on 19 March 2013

Role of Glucagon in Catabolism and Muscle Wasting of Critical Illness and Modulation by Nutrition

scientific article published on 5 May 2017

Serial lactate measurements using microdialysis of interstitial fluid do not correlate with plasma lactate in children after cardiac surgery

scientific article published on January 2009

Soluble RAGE and the RAGE ligands HMGB1 and S100A12 in critical illness: impact of glycemic control with insulin and relation with clinical outcome

scientific article published on February 2015

Supplementation of vitamins, trace elements and electrolytes in the PEPaNIC Randomised Controlled Trial: Composition and preparation of the prescription

scientific article published in 2021

Survival Benefits of Intensive Insulin Therapy in Critical Illness: Impact of Maintaining Normoglycemia Versus Glycemia-Independent Actions of Insulin

scientific article published on 01 April 2006

The GH Axis in Relation to Accepting an Early Macronutrient Deficit and Outcome of Critically Ill Patients

scientific article published on 01 November 2019

The Role of Autophagy in Critical Illness-induced Liver Damage

scientific article published on 26 October 2017

The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill.

scientific article

The altered adrenal axis and treatment with glucocorticoids during critical illness

scientific article

The authors reply

article published in 2014

The importance of strict blood glucose control with insulin therapy in the intensive care unit.

scientific article published on August 2008

The neuroendocrine response to critical illness is a dynamic process

scientific article published in January 2006

The pattern recognition molecule collectin-L1 in critically ill children

scientific article published on 8 April 2016

The role of insulin therapy in critically ill patients

scientific article

Therapy insight: the effect of tight glycemic control in acute illness

scientific article published on March 2007

Tight blood glucose control is renoprotective in critically ill patients

scientific article published on 30 January 2008

Tight blood glucose control with insulin in the ICU: facts and controversies

scientific article published on July 2007

Tight blood glucose control: what is the evidence?

scientific article published on September 2007

Tight glycemic control protects the myocardium and reduces inflammation in neonatal heart surgery

scientific article published on July 2010

Time course of altered DNA methylation evoked by critical illness and by early administration of parenteral nutrition in the paediatric ICU

scientific article published on 20 October 2020

Tissue mRNA expression of the glucocorticoid receptor and its splice variants in fatal critical illness

scientific article published on 13 October 2008

Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness

scientific article published in April 2009

What's new in the long-term neurodevelopmental outcome of critically ill children

scientific article

[Glycemic control in the intensive care unit].

scientific article published in May 2009

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