List of works - Derek T. Logan

A De Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch

scientific article

A Glycyl Radical Site in the Crystal Structure of a Class III Ribonucleotide Reductase

scientific article published in Science

A metal-binding site in the catalytic subunit of anaerobic ribonucleotide reductase

scientific article (publication date: April 2003)

A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies

scientific article

A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

scientific article published on 16 May 2022

A surface-exposed GH26 β-mannanase from Bacteroides ovatus: Structure, role, and phylogenetic analysis of BoMan26B

scientific article published on 18 April 2019

An Aspergillus nidulans β-mannanase with high transglycosylation capacity revealed through comparative studies within glycosidase family 5

scientific article

Are crystallographic B-factors suitable for calculating protein conformational entropy?

scientific article published on 01 August 2019

Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins

scientific article

Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH-Π interactions

scientific article

Closing the circle on ribonucleotide reductases ⬇️

scientific article published on 01 March 2011

Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.

scientific article

Crystal Structure of N -Glycosylated Human Glypican-1 Core Protein

scientific article

Crystal structure of a mutant elongation factor G trapped with a GTP analogue

scientific article published in August 2005

Crystal structure of human chondroadherin: solving a difficult molecular-replacement problem using de novo models

scientific article published in January 2017

Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP

scientific article

Crystallization and preliminary X-ray analysis of three serotypes of foot-and-mouth disease virus

scientific article published in December 1992

Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase

scientific article

Current status and future opportunities for serial crystallography at MAX IV Laboratory

scientific article published on 21 August 2020

DNA building blocks: keeping control of manufacture

scientific article

Deoxyribonucleotide synthesis in anaerobic microorganisms: the class III ribonucleotide reductase

scientific article

Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.

scientific article published on 4 December 2017

Elucidation of hydrogen bonding patterns in ligand-free, lactose- and glycerol-bound galectin-3C by neutron crystallography to guide drug design.

scientific article published on 19 April 2018

Exploring ligand dynamics in protein crystal structures with ensemble refinement

scientific article published on 29 July 2021

Expression, purification, crystallization and preliminary X-ray diffraction analysis of Thermotoga neapolitana beta-glucosidase B.

scientific article

Folding catalysis by transient coordination of Zn2+ to the Cu ligands of the ALS-associated enzyme Cu/Zn superoxide dismutase 1

scientific article

Folding of S6 structures with divergent amino acid composition: pathway flexibility within partly overlapping foldons

scientific article published on 12 September 2006

FragMAX: the fragment-screening platform at the MAX IV Laboratory

scientific article published on 27 July 2020

Functional features cause misfolding of the ALS-provoking enzyme SOD1

scientific article

Galactomannan Catabolism Conferred by a Polysaccharide Utilization Locus of Bacteroides ovatus: ENZYME SYNERGY AND CRYSTAL STRUCTURE OF A β-MANNANASE.

scientific article

Global structural motions from the strain of a single hydrogen bond

scientific article

High-resolution crystal structures of the flavoprotein NrdI in oxidized and reduced states--an unusual flavodoxin. Structural biology

scientific article

Implications of the inability of Listeria monocytogenes EGD-e to grow anaerobically due to a deletion in the class III NrdD ribonucleotide reductase for its use as a model laboratory strain

scientific article

Improvements in the order, isotropy and electron density of glypican-1 crystals by controlled dehydration

scientific article

Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding

scientific article published on 23 January 2019

Kinetics of transient radicals in Escherichia coli ribonucleotide reductase. Formation of a new tyrosyl radical in mutant protein R2.

scientific article

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

scientific article published on 21 March 2019

Modern mRNA proofreading and repair: clues that the last universal common ancestor possessed an RNA genome?

scientific article published in 2005

Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions.

scientific article

Neutron crystallographic studies reveal hydrogen bond and water-mediated interactions between a carbohydrate-binding module and its bound carbohydrate ligand

scientific article

Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit

scientific article published in February 2018

Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C

scientific article

Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area

scientific article published on 30 July 2009

Purification, crystallization and preliminary X-ray diffraction analysis of human chondroadherin

scientific article published on 23 May 2008

Refinement of protein structures using a combination of quantum-mechanical calculations with neutron and X-ray crystallographic data

Refinement of protein structures using a combination of quantum-mechanical calculations with neutron and X-ray crystallographic data. Corrigendum

scientific article published on 01 January 2020

Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates

scientific article

Small-angle X-ray Scattering Study of a Rex Family Repressor: Conformational Response to NADH and NAD+ Binding in Solution

article

Structural Aspects of N-Glycosylations and the C-terminal Region in Human Glypican-1.

scientific article

Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones

scientific article

Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones

scientific article published on 02 August 2016

Structural and Biophysical Characterization of Human EXTL3: Domain Organization, Glycosylation, and Solution Structure.

scientific article published on 18 January 2018

Structural and functional analyses of beta-glucosidase 3B from Thermotoga neapolitana: a thermostable three-domain representative of glycoside hydrolase 3

scientific article

Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus

scientific article published in October 1990

Structural basis for adenosylcobalamin activation in AdoCbl-dependent ribonucleotide reductases

scientific article

Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules

scientific article

Structural insights into fusidic acid resistance and sensitivity in EF-G.

scientific article published in May 2005

Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase

scientific article published on 10 October 2004

Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions

scientific article published on 11 July 2019

Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex

scientific article

Structure of a major immunogenic site on foot-and-mouth disease virus

scientific article

Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH.

scientific article

Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects

scientific article published on 01 January 2019

Synthesis of branched and linear 1,4-linked galactan oligosaccharides

scientific article

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

scientific article published on 28 December 2017

The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

scientific article

The Crystal Structure of Thermotoga maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site

scientific article published on 6 July 2015

The cost of long catalytic loops in folding and stability of the ALS-associated protein SOD1

scientific article published on 27 November 2018

The coupling between disulphide status, metallation and dimer interface strength in Cu/Zn superoxide dismutase

scientific article published on 23 September 2006

The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity

scientific article published on 04 April 2022

The evolution of the ribonucleotide reductases: much ado about oxygen

scientific article

The macromolecular crystallography beamline I911-3 at the MAX IV laboratory.

scientific article published on 18 May 2013

The origin and evolution of ribonucleotide reduction

scientific article

The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis

scientific article published on 08 June 2022

Thermodynamics of protein destabilization in live cells

scientific article

Tricking a Protein To Swap Strands.

scientific article

Trimming Down a Protein Structure to Its Bare Foldons: SPATIAL ORGANIZATION OF THE COOPERATIVE UNIT

scientific article

List of works by Derek T. Logan

A De Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch

A Glycyl Radical Site in the Crystal Structure of a Class III Ribonucleotide Reductase

A metal-binding site in the catalytic subunit of anaerobic ribonucleotide reductase

A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies

A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

A surface-exposed GH26 β-mannanase from Bacteroides ovatus: Structure, role, and phylogenetic analysis of BoMan26B

An Aspergillus nidulans β-mannanase with high transglycosylation capacity revealed through comparative studies within glycosidase family 5

Are crystallographic B-factors suitable for calculating protein conformational entropy?

Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins

Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH-Π interactions

Closing the circle on ribonucleotide reductases ⬇️

Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.

Crystal Structure of N -Glycosylated Human Glypican-1 Core Protein

Crystal structure of a mutant elongation factor G trapped with a GTP analogue

Crystal structure of human chondroadherin: solving a difficult molecular-replacement problem using de novo models

Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP

Crystallization and preliminary X-ray analysis of three serotypes of foot-and-mouth disease virus

Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase

Current status and future opportunities for serial crystallography at MAX IV Laboratory

DNA building blocks: keeping control of manufacture

Deoxyribonucleotide synthesis in anaerobic microorganisms: the class III ribonucleotide reductase

Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.

Elucidation of hydrogen bonding patterns in ligand-free, lactose- and glycerol-bound galectin-3C by neutron crystallography to guide drug design.

Exploring ligand dynamics in protein crystal structures with ensemble refinement

Expression, purification, crystallization and preliminary X-ray diffraction analysis of Thermotoga neapolitana beta-glucosidase B.

Folding catalysis by transient coordination of Zn2+ to the Cu ligands of the ALS-associated enzyme Cu/Zn superoxide dismutase 1

Folding of S6 structures with divergent amino acid composition: pathway flexibility within partly overlapping foldons

FragMAX: the fragment-screening platform at the MAX IV Laboratory

Functional features cause misfolding of the ALS-provoking enzyme SOD1

Galactomannan Catabolism Conferred by a Polysaccharide Utilization Locus of Bacteroides ovatus: ENZYME SYNERGY AND CRYSTAL STRUCTURE OF A β-MANNANASE.

Global structural motions from the strain of a single hydrogen bond

High-resolution crystal structures of the flavoprotein NrdI in oxidized and reduced states--an unusual flavodoxin. Structural biology

Implications of the inability of Listeria monocytogenes EGD-e to grow anaerobically due to a deletion in the class III NrdD ribonucleotide reductase for its use as a model laboratory strain

Improvements in the order, isotropy and electron density of glypican-1 crystals by controlled dehydration

Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding

Kinetics of transient radicals in Escherichia coli ribonucleotide reductase. Formation of a new tyrosyl radical in mutant protein R2.

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM

Modern mRNA proofreading and repair: clues that the last universal common ancestor possessed an RNA genome?

Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions.

Neutron crystallographic studies reveal hydrogen bond and water-mediated interactions between a carbohydrate-binding module and its bound carbohydrate ligand

Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit

Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C

Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area

Purification, crystallization and preliminary X-ray diffraction analysis of human chondroadherin

Refinement of protein structures using a combination of quantum-mechanical calculations with neutron and X-ray crystallographic data

Refinement of protein structures using a combination of quantum-mechanical calculations with neutron and X-ray crystallographic data. Corrigendum

Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates

Small-angle X-ray Scattering Study of a Rex Family Repressor: Conformational Response to NADH and NAD+ Binding in Solution

Structural Aspects of N-Glycosylations and the C-terminal Region in Human Glypican-1.

Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones

Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones

Structural and Biophysical Characterization of Human EXTL3: Domain Organization, Glycosylation, and Solution Structure.

Structural and functional analyses of beta-glucosidase 3B from Thermotoga neapolitana: a thermostable three-domain representative of glycoside hydrolase 3

Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus

Structural basis for adenosylcobalamin activation in AdoCbl-dependent ribonucleotide reductases

Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules

Structural insights into fusidic acid resistance and sensitivity in EF-G.

Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase

Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions

Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex

Structure of a major immunogenic site on foot-and-mouth disease virus

Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH.

Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects

Synthesis of branched and linear 1,4-linked galactan oligosaccharides

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

The Crystal Structure of Thermotoga maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site

The cost of long catalytic loops in folding and stability of the ALS-associated protein SOD1

The coupling between disulphide status, metallation and dimer interface strength in Cu/Zn superoxide dismutase

The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity

The evolution of the ribonucleotide reductases: much ado about oxygen

The macromolecular crystallography beamline I911-3 at the MAX IV laboratory.

The origin and evolution of ribonucleotide reduction

The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis

Thermodynamics of protein destabilization in live cells

Tricking a Protein To Swap Strands.

Trimming Down a Protein Structure to Its Bare Foldons: SPATIAL ORGANIZATION OF THE COOPERATIVE UNIT