List of works - Christos Chinopoulos

A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration

scientific article

A kinetic assay of mitochondrial ADP-ATP exchange rate in permeabilized cells.

scientific article

A novel kinetic assay of mitochondrial ATP-ADP exchange rate mediated by the ANT.

scientific article published on March 2009

A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+ release from mitochondria.

scientific article

ATP synthase complex and the mitochondrial permeability transition pore: poles of attraction

scientific article published on 19 June 2017

Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

scientific article

Absence of Ca2+-induced mitochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in C. crangon and P. serratus

scientific article

Acute sources of mitochondrial NAD+ during respiratory chain dysfunction

scientific article published on 05 February 2020

Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells

scientific article

Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder

scientific article published on 13 September 2018

Bioenergetics and the formation of mitochondrial reactive oxygen species.

scientific article published on 23 October 2006

Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme

scientific article

Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation

scientific article

Characterization of the N-acetylaspartate biosynthetic enzyme from rat brain

scientific article published in August 2003

Complex contribution of cyclophilin D to Ca2+-induced permeability transition in brain mitochondria, with relation to the bioenergetic state

scientific article

Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages

scientific article published on 23 January 2015

Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice.

scientific article published on 10 March 2017

Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: inhibition of alpha-ketoglutarate dehydrogenase

scientific article

Emergence of a spermine-sensitive, non-inactivating conductance in mature hippocampal CA1 pyramidal neurons upon reduction of extracellular Ca2+: dependence on intracellular Mg2+ and ATP.

scientific article published on 7 September 2006

Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation

scientific article published on 25 January 2020

Exclusive neuronal expression of SUCLA2 in the human brain

scientific article

Inhibition of glutamate-induced delayed calcium deregulation by 2-APB and La3+ in cultured cortical neurones

scientific article

Isolation and Functional Assessment of Mitochondria from Small Amounts of Mouse Brain Tissue ⬇️

scientific article published on January 1, 2011

Localization of SUCLA2 and SUCLG2 subunits of succinyl CoA ligase within the cerebral cortex suggests the absence of matrix substrate-level phosphorylation in glial cells of the human brain

scientific article

Measurement of ADP-ATP exchange in relation to mitochondrial transmembrane potential and oxygen consumption

scientific article

Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease

scientific article

Mitochondrial Ca2+ sequestration and precipitation revisited

scientific article published on 26 July 2010

Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis

article

Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

scientific article published in September 2004

Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury.

scientific article published in September 2004

Mitochondrial consumption of cytosolic ATP: not so fast.

scientific article published on 07 April 2011

Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.

scientific article published on 03 January 2014

Mitochondrial permeability transition pore: Back to the drawing board.

scientific article

Modeling of ATP-ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria.

scientific article published on 26 October 2009

Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

scientific journal article

Modulation of the mitochondrial permeability transition by cyclophilin D: moving closer to F(0)-F(1) ATP synthase?

scientific article published on 08 May 2011

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

scientific article published on 14 April 2014

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.

scientific article

Mutated SUCLG1 causes mislocalization of SUCLG2 protein, morphological alterations of mitochondria and an early-onset severe neurometabolic disorder

scientific article published on 16 November 2018

Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT.

scientific article published on 12 April 2018

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria

scientific article published on 10 April 2012

Response to "Leigh-like syndrome with mild mtDNA depletion due to the SUCLG1 variant c.626C>A"

scientific article published on 13 December 2018

Reversible depolarization of in situ mitochondria by oxidative stress parallels a decrease in NAD(P)H level in nerve terminals

scientific article published on 01 May 2000

Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios

scientific article (publication date: October 2016)

Succinate in ischemia: Where does it come from?

scientific article published on 05 August 2019

The "B space" of mitochondrial phosphorylation.

scientific article published on 03 May 2011

The Effect of 2-Ketobutyrate on Mitochondrial Substrate-Level Phosphorylation

scientific article published on 27 February 2019

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

scientific article published on 8 March 2013

The suppressor of AAC2 Lethality SAL1 modulates sensitivity of heterologously expressed artemia ADP/ATP carrier to bongkrekate in yeast

scientific article (publication date: 2013)

The ‘ins and outs’ of Ca2+ in mitochondria

scientific article published on 01 September 2010

Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma

scientific article published on 29 May 2019

Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations

scientific article published on 05 August 2016

What Makes You Can Also Break You, Part II: Mitochondrial Permeability Transition Pore Formation by Dimers of the F1FO ATP-Synthase?

scientific article published on 30 May 2013

What Makes You Can also Break You, Part III: Mitochondrial Permeability Transition Pore Formation by an Uncoupling Channel within the C-Subunit Ring of the F1FO ATP Synthase?

scientific article published on 3 September 2014

What makes you can also break you: mitochondrial permeability transition pore formation by the c subunit of the F(1)F(0) ATP-synthase?

scientific article published on 19 February 2013

Which way does the citric acid cycle turn during hypoxia? The critical role of α-ketoglutarate dehydrogenase complex.

scientific article published on February 2013

List of works by Christos Chinopoulos

A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration

A kinetic assay of mitochondrial ADP-ATP exchange rate in permeabilized cells.

A novel kinetic assay of mitochondrial ATP-ADP exchange rate mediated by the ANT.

A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+ release from mitochondria.

ATP synthase complex and the mitochondrial permeability transition pore: poles of attraction

Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

Absence of Ca2+-induced mitochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in C. crangon and P. serratus

Acute sources of mitochondrial NAD+ during respiratory chain dysfunction

Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells

Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder

Bioenergetics and the formation of mitochondrial reactive oxygen species.

Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme

Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation

Characterization of the N-acetylaspartate biosynthetic enzyme from rat brain

Complex contribution of cyclophilin D to Ca2+-induced permeability transition in brain mitochondria, with relation to the bioenergetic state

Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages

Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice.

Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: inhibition of alpha-ketoglutarate dehydrogenase

Emergence of a spermine-sensitive, non-inactivating conductance in mature hippocampal CA1 pyramidal neurons upon reduction of extracellular Ca2+: dependence on intracellular Mg2+ and ATP.

Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation

Exclusive neuronal expression of SUCLA2 in the human brain

Inhibition of glutamate-induced delayed calcium deregulation by 2-APB and La3+ in cultured cortical neurones

Isolation and Functional Assessment of Mitochondria from Small Amounts of Mouse Brain Tissue ⬇️

Localization of SUCLA2 and SUCLG2 subunits of succinyl CoA ligase within the cerebral cortex suggests the absence of matrix substrate-level phosphorylation in glial cells of the human brain

Measurement of ADP-ATP exchange in relation to mitochondrial transmembrane potential and oxygen consumption

Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease

Mitochondrial Ca2+ sequestration and precipitation revisited

Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis

Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury.

Mitochondrial consumption of cytosolic ATP: not so fast.

Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.

Mitochondrial permeability transition pore: Back to the drawing board.

Modeling of ATP-ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria.

Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

Modulation of the mitochondrial permeability transition by cyclophilin D: moving closer to F(0)-F(1) ATP synthase?

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.

Mutated SUCLG1 causes mislocalization of SUCLG2 protein, morphological alterations of mitochondria and an early-onset severe neurometabolic disorder

Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT.

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria

Response to "Leigh-like syndrome with mild mtDNA depletion due to the SUCLG1 variant c.626C>A"

Reversible depolarization of in situ mitochondria by oxidative stress parallels a decrease in NAD(P)H level in nerve terminals

Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios

Succinate in ischemia: Where does it come from?

The "B space" of mitochondrial phosphorylation.

The Effect of 2-Ketobutyrate on Mitochondrial Substrate-Level Phosphorylation

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

The suppressor of AAC2 Lethality SAL1 modulates sensitivity of heterologously expressed artemia ADP/ATP carrier to bongkrekate in yeast

The ‘ins and outs’ of Ca2+ in mitochondria

Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma

Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations

What Makes You Can Also Break You, Part II: Mitochondrial Permeability Transition Pore Formation by Dimers of the F1FO ATP-Synthase?

What Makes You Can also Break You, Part III: Mitochondrial Permeability Transition Pore Formation by an Uncoupling Channel within the C-Subunit Ring of the F1FO ATP Synthase?

What makes you can also break you: mitochondrial permeability transition pore formation by the c subunit of the F(1)F(0) ATP-synthase?

Which way does the citric acid cycle turn during hypoxia? The critical role of α-ketoglutarate dehydrogenase complex.