Search filters

List of works by Laura E. Edgington

A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages

scientific article

An optimized activity-based probe for the study of caspase-6 activation

scientific article published in March 2012

Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2.

scientific article published on 16 July 2016

Application of a Sulfoxonium Ylide Electrophile to Generate Cathepsin X-Selective Activity-Based Probes

scientific article published on 14 February 2020

Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

scientific article published on 16 September 2019

Cathepsin B inhibition limits bone metastasis in breast cancer

scientific article published on 19 January 2012

Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity

scientific article published in 2009

Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer

scientific article

Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe

scientific article published on 24 August 2015

Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo

scientific article published on 21 October 2013

Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation

scientific article published on 25 November 2016

Functional imaging of legumain in cancer using a new quenched activity-based probe

scientific article published on 18 December 2012

Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes ⬇️

scientific article published on November 16, 2011

In vivo imaging and biochemical characterization of protease function using fluorescent activity-based probes

scientific article published on January 2013

Ion Mobility–Based Enrichment-Free N-Terminomics Analysis Reveals Novel Legumain Substrates in Murine Spleen

scientific article published in 2024

Legumain is activated in macrophages during pancreatitis

scientific article published on 11 August 2016

Live Cell Imaging and Profiling of Cysteine Cathepsin Activity Using a Quenched Activity-Based Probe

scientific article published in January 2017

Long noncoding RNAs: novel links to inflammatory bowel disease?

scientific article published on 4 August 2016

Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion

scientific article

N-Terminomics/TAILS Profiling of Macrophages after Chemical Inhibition of Legumain

scientific article published on 27 November 2019

Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe

scientific article

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

scientific article

Novel broad-spectrum activity-based probes to profile malarial cysteine proteases

scientific article published on 10 January 2020

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

article by Chaido Stathopoulou et al published 21 August 2018 in Immunity

Pathophysiological roles of proteases in gastrointestinal disease

scientific article published on 23 December 2015

Probes to monitor activity of the paracaspase MALT1.

scientific article

Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome

article published in the Proceedings of the National Academy of Sciences of the United States of America

The apoptosis repressor with a CARD domain (ARC) gene is a direct hypoxia-inducible factor 1 target gene and promotes survival and proliferation of VHL-deficient renal cancer cells

scientific article published on 16 December 2013

Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model

scientific article published on 13 October 2011

Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86

scientific article published on 11 April 2022

Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity

scientific article

Paulina is supported by:

About Paulina

Help