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List of works by Adam McCluskey

(Z)-2-(3,4-Dichlorophenyl)-3-(1H-Pyrrol-2-yl)Acrylonitrile Exhibits Selective Antitumor Activity in Breast Cancer Cell Lines via the Aryl Hydrocarbon Receptor Pathway.

scientific article published on 21 December 2017

1,8-Naphthalimide derivatives: new leads against dynamin I GTPase activity

scientific article published on 29 June 2015

2-Pyridylnitrene from tetrazolo[1,5-a]pyridine and pyrido[2,3-a][1,2,4]oxadiazol-2-one

scientific article published on 23 July 2008

A 'cold synthesis' of heroin and implications in heroin signature analysis utility of trifluoroacetic/acetic anhydride in the acetylation of morphine

scientific article published on 23 March 2006

A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High-Throughput Screening: Application to O-GlcNAc Transferase

scientific article published on 24 February 2020

A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells ⬇️

scientific article published on August 15, 2013

A facile hybrid 'flow and batch' access to substituted 3,4-dihydro-2H-benzo[b][1,4]oxazinones

scientific article

A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone.

scientific article published on 4 April 2018

A highly atom efficient, solvent promoted addition of tetraallylic, tetraallenic, and tetrapropargylic stannanes to carbonyl compounds

scientific article published in November 2001

Actin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletion

scientific article (publication date: 2012)

Amino Alcohol Acrylonitriles as Activators of the Aryl Hydrocarbon Receptor Pathway: An Unexpected MTT Phenotypic Screening Outcome

scientific article published on 28 February 2020

Amino Alcohols as Potential Antibiotic and Antifungal Leads

scientific article published on 22 March 2022

Aminoguanidines: New leads for treatment of Giardia duodenalis infection

scientific article published on 08 April 2019

An ATR‐FTIR Study on the Effect of Molecular Structural Variations on the CO2 Absorption Characteristics of Heterocyclic Amines, Part II ⬇️

scientific article (publication date: 18 June 2012)

An FTIR spectroscopic study on the effect of molecular structural variations on the CO2 absorption characteristics of heterocyclic amines

scientific article published on 5 April 2011

An efficient continuous flow approach to furnish furan-based biaryls

scientific article published on 21 October 2014

An extreme vertices mixture design approach to the optimisation of 1,2,3-trichlorobenzene specific molecularly imprinted polymers

scientific article published on 10 June 2013

An integrated flow and microwave approach to a broad spectrum protein kinase inhibitor

scholarly article in RSC Advances, vol. 5 no. 113, 2015

Analysis of synaptic vesicle endocytosis in synaptosomes by high-content screening.

scientific article

Anhydride modified cantharidin analogues: synthesis, inhibition of protein phosphatases 1 and 2A and anticancer activity.

scientific article published on August 2000

Anti-malarial, anti-algal, anti-tubercular, anti-bacterial, anti-photosynthetic, and anti-fouling activity of diterpene and diterpene isonitriles from the tropical marine sponge Cymbastela hooperi

scientific article published on 2 November 2010

Anticancer activity and protein phosphatase 1 and 2A inhibition of a new generation of cantharidin analogues

scientific article

Australian Federal Police seizures of illicit crystalline methamphetamine ('ice') 1998-2002: impurity analysis

scientific article published on 20 March 2006

Auto-inhibition of Ca(2+)/calmodulin-dependent protein kinase II by its ATP-binding domain.

scientific article

Azido and diazarinyl analogues of bis-tyrphostin as asymmetrical inhibitors of dynamin GTPase

scientific article published on July 2009

Back to (non-)Basics: An Update on Neutral and Charge-Balanced Glycosidase Inhibitors

scientific article published on 2 October 2017

Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis

scientific article published on 9 October 2013

Calcineurin activity is required for the completion of cytokinesis

scientific article

Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines

scientific article published on February 2003

Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.

scientific article published in November 2001

Characterization of a novel role for the dynamin mechanoenzymes in the regulation of human sperm acrosomal exocytosis

scientific article published in October 2017

Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors

scientific article published on 09 January 2014

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

scientific article

Corticotropin releasing hormone: therapeutic implications and medicinal chemistry developments.

scientific article published in June 2000

Crystal Structure of Ethyl 2,4-Dimethyl-1-phenyl-6-thioxo-1,6-dihydropyrimidine-5-carboxylate: The Product from the Reaction of Ethyl 3-Aminocrotonate, Phenylisothiocyanate and Acetic Anhydride

Cytotoxic 2-phenyacrylnitriles, the importance of the cyanide moiety and discovery of potent broad spectrum cytotoxic agents

scientific article

Cytotoxic compounds from Laurencia pacifica

scientific article published on 20 September 2014

Cytotoxicity of a Series of Norcantharidin-Inspired Tetrahydroepoxyisoindole Carboxamides.

scientific article published on 06 December 2016

Damaging legacy: maternal cigarette smoking has long-term consequences for male offspring fertility.

scientific article published on 30 September 2014

Development of 1,8-naphthalimides as clathrin inhibitors

scientific article

Development of quinone analogues as dynamin GTPase inhibitors

scientific article

Development of second-generation indole-based dynamin GTPase inhibitors

scientific article

Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis

scientific article

Dichlorophenylacrylonitriles as AhR Ligands That Display Selective Breast Cancer Cytotoxicity in vitro

scientific article published on 02 July 2018

Diimidazo[1,2-c:4',5'-e]pyrimidines: N6-N1 conformationally restricted adenosines.

scientific article published in March 1998

Discovery of 4,6-bis(2-((E)-benzylidene)hydrazinyl)pyrimidin-2-Amine with Antibiotic Activity

scientific article published on 04 July 2019

Discovery of acrylonitrile-based small molecules active against Haemonchus contortus

Dynamin 2 is essential for mammalian spermatogenesis.

scientific article published on 11 October 2016

Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism

scientific article

Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa.

scientific article

Effect of template on the formation of phase-inversed molecularly imprinted polymer thin films: an assessment

Efficient preparation and improved sensitivity of molecularly imprinted polymers using room temperature ionic liquids

scientific article published on 09 March 2006

Evaluation of 4-substituted styrenes as functional monomers for the synthesis of theophylline-specific molecularly imprinted polymers

scientific article published on 01 September 2014

Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent

scientific article

FD5180, a Novel Protein Kinase Affinity Probe, and the Effect of Bead Loading on Protein Kinase Identification

Focused library development of 2-phenylacrylamides as broad spectrum cytotoxic agents

scientific article

From Spanish fly to room-temperature ionic liquids (RTILs): synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs

article

Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation.

scientific article published on 25 March 2015

Gram-positive and Gram-negative Antibiotic Activity of Asymmetric and Monomeric Robenidine Analogues

scientific article published on 19 November 2018

Green chemistry approaches to the Knoevenagel condensation: comparison of ethanol, water and solvent free (dry grind) approaches

HIV infection is influenced by dynamin at 3 independent points in the viral life cycle.

scientific article published on 21 March 2017

Hedgehog signalling pathway inhibitors as cancer suppressing agents

Heterocyclic substituted cantharidin and norcantharidin analogues—synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity

scientific article published on 02 April 2007

Identification and validation of small molecule modulators of the NusB-NusE interaction.

scientific article

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis

scientific article

In Silico Docking, Molecular Dynamics and Binding Energy Insights into the Bolinaquinone-Clathrin Terminal Domain Binding Site

article

In situ epoxide generation by dimethyldioxirane oxidation and the use of epichlorohydrin in the flow synthesis of a library of β-amino alcohols.

scientific article published on 4 April 2018

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

scientific article published on 17 January 2013

Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells

scientific article published on 12 July 2011

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles

scientific article

Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction

scientific article published on 01 March 2011

Ionic liquids as porogens for molecularly imprinted polymers: propranolol, a model study

article

Isolation and identification of unique marker compounds from the Tasmanian poppy Papaver somniferum N. Implications for the identification of illicit heroin of Tasmanian origin.

scientific article

Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity

scientific article

Microwave induced MIP synthesis: comparative analysis of thermal and microwave induced polymerisation of caffeine imprinted polymers

article

Modified norcantharidins; synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity

scientific article published on April 2004

Molecular dynamics approaches to the design and synthesis of PCB targeting molecularly imprinted polymers: interference to monomer-template interactions in imprinting of 1,2,3-trichlorobenzene.

scientific article published on 16 December 2013

Molecularly imprinted films of acrylonitrile/methyl methacrylate/acrylic acid terpolymers: influence of methyl methacrylate in the binding performance of L-ephedrine imprinted films

scientific article published on 18 March 2013

Myristyl Trimethyl Ammonium Bromide and Octadecyl Trimethyl Ammonium Bromide Are Surface-Active Small Molecule Dynamin Inhibitors that Block Endocytosis Mediated by Dynamin I or Dynamin II

scientific article published on 16 August 2007

N-2-Propenyl-(5-dimethylamino)-1-naphthalene Sulfonamide, a Novel Fluorescent Monomer for the Molecularly Imprinted Polymer-Based Detection of 2,4-Dinitrotoluene in the Gas Phase

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

scientific article published on May 2017

New impurity profiles of recent Australian imported ‘ice’: Methamphetamine impurity profiling and the identification of (pseudo)ephedrine and Leuckart specific marker compounds

article

Norcantharidin analogues with nematocidal activity in Haemonchus contortus

scientific article published on 13 April 2011

Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition

scientific article

Norcantharimide analogues possessing terminal phosphate esters and their anti-cancer activity ⬇️

scientific article published on September 15, 2011

Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation

scientific article published on 20 June 2007

Parallel Solution-Phase Synthesis of Targeted Tyrphostin Libraries with Anticancer Activity

Pharmacophore development for corticotropin-releasing hormone: new insights into inhibitor activity.

scientific article published on July 1999

Phenothiazine-derived antipsychotic drugs inhibit dynamin and clathrin-mediated endocytosis

scientific article published on 9 April 2015

Protein phosphatase inhibition: structure based design. Towards new therapeutic agents

scientific article published on January 2004

Protein-protein interactions as antibiotic targets: A medicinal chemistry perspective

scholarly article by Peter J. Cossar et al published 13 July 2018 in Medicinal Research Reviews

Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.

scientific article

Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.

scientific article

Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors

scientific article published on 7 June 2016

Robenidine Analogues as Gram-Positive Antibacterial Agents

scientific article published on 10 February 2016

Role of dynamin in elongated cell migration in a 3D matrix

scientific article

Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition

scientific article

Scrambled and fried: cigarette smoke exposure causes antral follicle destruction and oocyte dysfunction through oxidative stress.

scientific article published on 18 May 2013

Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies

scientific article

Serine/threonine phosphatases in socioeconomically important parasitic nematodes—Prospects as novel drug targets? ⬇️

scientific article published on August 21, 2010

Serine/threonine protein phosphatase inhibition enhances the effect of thymidylate synthase inhibition

scientific article published on 25 November 2003

Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway

scientific article

Small molecule Hedgehog pathway antagonists

scientific article

Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells

scientific article published on 04 December 2020

Small molecule inhibitors of dynamin I GTPase activity: development of dimeric tyrphostins

scientific article published in December 2005

Small molecule inhibitors of protein kinases in cancer- how to overcome resistance.

scientific article published on October 2006

Small molecules demonstrate the role of dynamin as a bi-directional regulator of the exocytosis fusion pore and vesicle release

scientific article published on 5 May 2015

Small-Molecule Inhibitors of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity

scientific article published on 25 July 2017

Steroids from an Australian sponge Psammoclema sp.

scientific article published in January 2009

Synthesis and Cytotoxicity of Octahydroepoxyisoindole-7-carboxylic Acids and Norcantharidin-Amide Hybrids as Norcantharidin Analogues

scientific article published on 14 May 2019

Synthesis and anticancer activity of a series of norcantharidin analogues

scientific article

Synthesis and anticancer activity of focused compound libraries from the natural product lead, oroidin

scientific article

Synthesis and biological activity of Delta-5,6-norcantharimides: importance of the 5,6-bridge

scientific article

Synthesis and biological evaluation of norcantharidin analogues: Towards PP1 selectivity

scientific article published on 24 August 2007

Synthesis and evaluation of novel ellipticines as potential anti-cancer agents

scientific article published on February 2013

Synthesis of Dynole 34-2, Dynole 2-24 and Dyngo 4a for investigating dynamin GTPase

Synthesis of the Pitstop family of clathrin inhibitors

Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists.

scientific article

Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors

scientific article

Tetrabromocyclopentadienylidene: generation and reaction with CO in low temperature matrices

The Bispidinone Derivative 3,7-Bis-[2-(S)-amino-3-(1H-indol-3-yl)-propionyl]-1,5-diphenyl-3,7-diazabicyclo[3.3.1]nonan-9-one Dihydrochloride Induces an Apoptosis-Mediated Cytotoxic Effect on Pancreatic Cancer Cells In Vitro

scientific article published on 31 January 2019

The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity

scientific article

The antiplasmodial activity of norcantharidin analogs.

scientific article published on 7 September 2010

The aryl hydrocarbon receptor (AhR) as a breast cancer drug target

scientific article published on 12 November 2019

The crystal structures of 3-O-benzyl-1,2-O-isopropylidene-5-O-methanesulfonyl-6-O-triphenylmethyl-α-d-glucofuranose and its azide displacement product.

scientific article

The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells

scientific article published on 22 June 2010

The expanding utility of continuous flow hydrogenation

scientific article published on 15 June 2015

The first two cantharidin analogues displaying PP1 selectivity

scientific article published in February 2002

The pthaladyns: GTP competitive inhibitors of dynamin I and II GTPase derived from virtual screening

scientific article

The role of the HPA axis in psychiatric disorders and CRF antagonists as potential treatments.

scientific article published on July 2006

The synthesis and biological activity of novel anthracenone-pyranones and anthracenone-furans

scientific article published on 22 April 2015

The use of effective fragment potentials in the design and synthesis of molecularly imprinted polymers for the group recognition of PCBs

scientific article published on 10 June 2013

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