List of works - Henrik J. Ditzel

CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial

scientific article published on 6 March 2012

Neutralization of Human Immunodeficiency Virus Type 1 by Antibody to gp120 Is Determined Primarily by Occupancy of Sites on the Virion Irrespective of Epitope Specificity

scientific article published on May 1, 1998

Oncogenic cancer/testis antigens: prime candidates for immunotherapy.

scientific article published on June 2015

Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site.

scientific article published on June 1995

Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease

scientific article published in August 2001

Stromal CD8+ T-cell Density—A Promising Supplement to TNM Staging in Non–Small Cell Lung Cancer

scientific article published on 13 February 2015

Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: a case control study.

scientific article

Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry.

scientific article published on 24 March 2009

Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells

scientific article published on 16 September 2013

The tumor-infiltrating B cell response in medullary breast cancer is oligoclonal and directed against the autoantigen actin exposed on the surface of apoptotic cancer cells.

scientific article

The K/BxN mouse: a model of human inflammatory arthritis.

scientific article published on January 2004

Functional Heterogeneity within the CD44 High Human Breast Cancer Stem Cell-Like Compartment Reveals a Gene Signature Predictive of Distant Metastasis

scientific article published on September 25, 2012

Identification of genes for normalization of real-time RT-PCR data in breast carcinomas

scientific article

The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer.

scientific article published in July 2012

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

scientific article

Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC.

scientific article

Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study

scientific article (publication date: 2012)

Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

scientific article published on 4 September 2017

Efficient isolation and quantitative proteomic analysis of cancer cell plasma membrane proteins for identification of metastasis-associated cell surface markers.

scientific article published on June 2009

MAGE-A1, GAGE and NY-ESO-1 cancer/testis antigen expression during human gonadal development

scientific article published on 5 January 2007

KeyPathwayMiner 4.0: condition-specific pathway analysis by combining multiple omics studies and networks with Cytoscape.

scientific article

Discriminating isogenic cancer cells and identifying altered unsaturated fatty acid content as associated with metastasis status, using k-means clustering and partial least squares-discriminant analysis of Raman maps

scientific article

Phage display derived human monoclonal antibodies isolated by binding to the surface of live primary breast cancer cells recognize GRP78.

scientific article

Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.

scientific article published on January 1995

Gene expression profiling identifies FYN as an important molecule in tamoxifen resistance and a predictor of early recurrence in patients treated with endocrine therapy.

scientific article

Distinct GAGE and MAGE-A expression during early human development indicate specific roles in lineage differentiation

scientific article published on 8 July 2008

Association of autoantibodies to glucose-6-phosphate isomerase with extraarticular complications in rheumatoid arthritis

scientific article published in February 2004

Fyn is an important molecule in cancer pathogenesis and drug resistance.

scientific article published on 21 August 2015

A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library.

scientific article published in December 2002

High CDK6 Protects Cells from Fulvestrant-Mediated Apoptosis and is a Predictor of Resistance to Fulvestrant in Estrogen Receptor-Positive Metastatic Breast Cancer

scientific article

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

scientific article

Translocation of an intracellular antigen to the surface of medullary breast cancer cells early in apoptosis allows for an antigen-driven antibody response elicited by tumor-infiltrating B cells

article

Determinants of polyreactivity in a large panel of recombinant human antibodies from HIV-1 infection.

scientific article published on July 1996

Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display

scientific article

Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo

scientific article published on 27 February 2016

Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

scientific article

Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence.

scientific article

Autoantibodies against C1q in systemic lupus erythematosus are antigen-driven

scientific article

KeyPathwayMinerWeb: online multi-omics network enrichment.

scientific article published on 5 May 2016

Simian Immunodeficiency Virus (SIV) Envelope-Specific Fabs with High-Level Homologous Neutralizing Activity: Recovery from a Long-Term-Nonprogressor SIV-Infected Macaque

scientific article published on January 1, 1998

De novo pathway-based biomarker identification.

scientific article published in September 2017

Cancer-associated cleavage of cytokeratin 8/18 heterotypic complexes exposes a neoepitope in human adenocarcinomas

scientific article

Cloning and expression of a novel human antibody-antigen pair associated with Felty's syndrome.

scientific article published on August 2000

A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents.

scientific article

Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis.

scientific article published on 30 September 2004

Modified cytokeratins expressed on the surface of carcinoma cells undergo endocytosis upon binding of human monoclonal antibody and its recombinant Fab fragment.

scientific article

Decorin is down-regulated in multiple myeloma and MGUS bone marrow plasma and inhibits HGF-induced myeloma plasma cell viability and migration

scientific article published on 7 July 2013

Epigenetic modulation of cancer-germline antigen gene expression in tumorigenic human mesenchymal stem cells: implications for cancer therapy

scientific article published on 4 June 2009

Tumor-selective replication herpes simplex virus-based technology significantly improves clinical detection and prognostication of viable circulating tumor cells.

scientific article published on 18 May 2016

The first dose of a Haemophilus influenzae type b conjugate vaccine reactivates memory B cells: evidence for extensive clonal selection, intraclonal affinity maturation, and multiple isotype switches to IgA2.

scientific article published on January 1999

List of works by Henrik J. Ditzel

CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial

Neutralization of Human Immunodeficiency Virus Type 1 by Antibody to gp120 Is Determined Primarily by Occupancy of Sites on the Virion Irrespective of Epitope Specificity

Oncogenic cancer/testis antigens: prime candidates for immunotherapy.

Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site.

Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease

Stromal CD8+ T-cell Density—A Promising Supplement to TNM Staging in Non–Small Cell Lung Cancer

Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: a case control study.

Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry.

Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells

The tumor-infiltrating B cell response in medullary breast cancer is oligoclonal and directed against the autoantigen actin exposed on the surface of apoptotic cancer cells.

The K/BxN mouse: a model of human inflammatory arthritis.

Functional Heterogeneity within the CD44 High Human Breast Cancer Stem Cell-Like Compartment Reveals a Gene Signature Predictive of Distant Metastasis

Identification of genes for normalization of real-time RT-PCR data in breast carcinomas

The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer.

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC.

Global microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG study

Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

Efficient isolation and quantitative proteomic analysis of cancer cell plasma membrane proteins for identification of metastasis-associated cell surface markers.

MAGE-A1, GAGE and NY-ESO-1 cancer/testis antigen expression during human gonadal development

KeyPathwayMiner 4.0: condition-specific pathway analysis by combining multiple omics studies and networks with Cytoscape.

Discriminating isogenic cancer cells and identifying altered unsaturated fatty acid content as associated with metastasis status, using k-means clustering and partial least squares-discriminant analysis of Raman maps

Phage display derived human monoclonal antibodies isolated by binding to the surface of live primary breast cancer cells recognize GRP78.

Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.

Gene expression profiling identifies FYN as an important molecule in tamoxifen resistance and a predictor of early recurrence in patients treated with endocrine therapy.

Distinct GAGE and MAGE-A expression during early human development indicate specific roles in lineage differentiation

Association of autoantibodies to glucose-6-phosphate isomerase with extraarticular complications in rheumatoid arthritis

Fyn is an important molecule in cancer pathogenesis and drug resistance.

A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library.

High CDK6 Protects Cells from Fulvestrant-Mediated Apoptosis and is a Predictor of Resistance to Fulvestrant in Estrogen Receptor-Positive Metastatic Breast Cancer

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

Translocation of an intracellular antigen to the surface of medullary breast cancer cells early in apoptosis allows for an antigen-driven antibody response elicited by tumor-infiltrating B cells

Determinants of polyreactivity in a large panel of recombinant human antibodies from HIV-1 infection.

Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display

Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo

Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence.

Autoantibodies against C1q in systemic lupus erythematosus are antigen-driven

KeyPathwayMinerWeb: online multi-omics network enrichment.

Simian Immunodeficiency Virus (SIV) Envelope-Specific Fabs with High-Level Homologous Neutralizing Activity: Recovery from a Long-Term-Nonprogressor SIV-Infected Macaque

De novo pathway-based biomarker identification.

Cancer-associated cleavage of cytokeratin 8/18 heterotypic complexes exposes a neoepitope in human adenocarcinomas

Cloning and expression of a novel human antibody-antigen pair associated with Felty's syndrome.

A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents.

Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis.

Modified cytokeratins expressed on the surface of carcinoma cells undergo endocytosis upon binding of human monoclonal antibody and its recombinant Fab fragment.

Decorin is down-regulated in multiple myeloma and MGUS bone marrow plasma and inhibits HGF-induced myeloma plasma cell viability and migration

Epigenetic modulation of cancer-germline antigen gene expression in tumorigenic human mesenchymal stem cells: implications for cancer therapy

Tumor-selective replication herpes simplex virus-based technology significantly improves clinical detection and prognostication of viable circulating tumor cells.

The first dose of a Haemophilus influenzae type b conjugate vaccine reactivates memory B cells: evidence for extensive clonal selection, intraclonal affinity maturation, and multiple isotype switches to IgA2.