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List of works by Maria Sibilia

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor

scientific article

ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.

scientific article published on 22 February 2018

Afatinib restrains K-RAS–driven lung tumorigenesis

scientific article published on 01 June 2018

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

scientific article (publication date: March 1999)

Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor.

scientific article published on 17 January 2013

Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development

scientific article

Autophagy regulation in pancreatic acinar cells is independent of epidermal growth factor receptor signaling

scientific article published on 4 March 2014

BRAF and MEK inhibitors increase PD1-positive melanoma cells leading to a potential lymphocyte-independent synergism with anti-PD1 antibody.

scientific article published on 12 April 2018

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis

scientific article published on 16 February 2018

CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin

scientific article published on 4 May 2015

Consequences of epidermal growth factor receptor (ErbB1) loss for vascular smooth muscle cells from mice with targeted deletion of ErbB1.

scientific article published on 21 April 2011

Consequences of postnatal vascular smooth muscle EGFR deletion on acute angiotensin II action

scientific article published on 5 October 2015

Covalent Dimerization of Interleukin-Like Epithelial-to-Mesenchymal Transition (EMT) Inducer (ILEI) Facilitates EMT, Invasion and Late Aspects of Metastasis

scientific article published on 24 August 2017

Defective angiogenesis delays thrombus resolution: a potential pathogenetic mechanism underlying chronic thromboembolic pulmonary hypertension

scientific article published on 13 February 2014

Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes

scientific article

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon

scientific article published in April 1999

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

scientific article

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

scientific journal article

EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma

scientific article published on September 2012

EGFR Signaling in Liver Diseases

scientific article

EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.

scientific article published on 14 February 2018

EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation

scientific article

EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients

scientific article published on 8 April 2017

EGFR inhibitors erlotinib and lapatinib ameliorate epidermal blistering in pemphigus vulgaris in a non-linear, V-shaped relationship

scientific article

EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling

scientific article published on 01 November 2018

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma

scientific article

Early embryonic lethality of mice lacking the essential protein SNEV

scientific article

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

scientific article

Effects of Depilation Methods on Imiquimod-Induced Skin Inflammation in Mice

scientific article published on 30 September 2016

Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression

scientific article published in July 2016

Epidermal EGFR controls cutaneous host defense and prevents inflammation

scientific article published in August 2013

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion

scientific article published on October 2017

Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease

scientific article published on 08 January 2020

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

scientific article

Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis

scientific article

Evidence That Cingulin Regulates Endothelial Barrier Function In Vitro and In Vivo

scientific article published on 28 January 2016

Feasibility of personalized treatment concepts in gastrointestinal malignancies: Sub-group results of prospective clinical phase II trial EXACT

article published in 2018

Functions of c-Jun in liver and heart development

scientific journal article

Guidelines for vaccination of immunocompromised individuals

scientific article published on 25 July 2016

Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy

scientific article published on 01 December 2019

Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions

scientific article

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

scientific article published in February 2012

Hepatocyte-specific deletion of EGFR in mice reduces hepatic Abcg2 transport activity measured with [(11)C]erlotinib and positron emission tomography

scientific article published on 08 August 2017

High-Affinity IgE Receptors on Dendritic Cells Exacerbate Th2-Dependent Inflammation

scientific article published on 27 May 2011

How imiquimod licenses plasmacytoid dendritic cells to kill tumors

scientific article

Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod

scientific article

Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

scientific article published on 17 January 2012

Impaired neural stem cell expansion and hypersensitivity to epileptic seizures in mice lacking the EGFR in the brain

scientific article published on 04 August 2018

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

scientific article

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

scientific article published on 01 June 2018

Loss of epidermal growth factor receptor in vascular smooth muscle cells and cardiomyocytes causes arterial hypotension and cardiac hypertrophy

scientific article published on 17 December 2012

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

scientific article (publication date: 2 November 2001)

Mechanisms underlying skin disorders induced by EGFR inhibitors

scientific article

Methods to study MAP kinase signalling in the central nervous system.

scientific article

Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart

scientific article

Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor

scientific article

Molecular oncology in lung cancer – between biomarkers and clinical application. Relevance of the Ras–Raf–MEK–ERK pathway

Mouse Models of Receptor Tyrosine Kinases

Mouse models of nonmelanoma skin cancer

scientific article published on January 2015

Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes

scientific article

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

scientific article (publication date: 18 May 2000)

Osteopontin-deficient progenitor cells display enhanced differentiation to adipocytes

scientific article published on 6 March 2018

Qualitative and quantitative re-evaluation of epidermal growth factor-ErbB1 action on developing midbrain dopaminergic neurons in vivo and in vitro: target-derived neurotrophic signaling (Part 1).

scientific article published on 19 May 2011

RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure

scientific article published on 07 August 2018

Raf-1 addiction in Ras-induced skin carcinogenesis

scientific article published in August 2009

Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells

scientific article published on 20 January 2016

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

scientific article published on 14 December 2015

Sequential cooperation of CD2 and CD48 in the buildup of the early TCR signalosome

scientific article published in June 2009

Skin Inflammation Is Not Sufficient to Break Tolerance Induced against a Novel Antigen

scientific article published on 01 July 2009

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

scientific article

Strain-dependent epithelial defects in mice lacking the EGF receptor

scientific article

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins

scientific article published on November 2009

TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo

scientific article published on 17 January 2014

The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity

scientific article published on 23 March 2021

The EGF receptor is required for efficient liver regeneration

scholarly article

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

scientific article

The EGFR network in bone biology and pathology

scientific article published on 12 October 2009

The cytoplasmic tail of CD45 is released from activated phagocytes and can act as an inhibitory messenger for T cells

scientific article published on 29 May 2008

The epidermal growth factor receptor: from development to tumorigenesis

scientific article published on November 2007

The protein tyrosine kinase Tec regulates mast cell function

scientific article published in November 2009

Transgenic animals

c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

scientific article published on June 2003

hVps37A Status affects prognosis and cetuximab sensitivity in ovarian cancer

scientific article published on 20 October 2011

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