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List of works by Xiaoyu Hu

Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors

scientific article published on 3 October 2004

Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1.

scientific article published on 24 September 2010

Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells

scholarly article by Fuyu Duan et al published 27 July 2018 in Stem Cell Research & Therapy

Combining Vγ9Vδ2 T Cells with a Lipophilic Bisphosphonate Efficiently Kills Activated Hepatic Stellate Cells

scientific article published on 24 October 2017

Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival

scientific article published on 05 November 2019

Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases

scientific article published on October 2009

Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation

scientific article published on 14 May 2007

Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.

scientific article

Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade

scientific article published on 01 September 2020

Epithelial Hes1 maintains gut homeostasis by preventing microbial dysbiosis

scientific article published on 3 January 2018

FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin

scientific article

Gene-specific mechanisms direct Glucocorticoid Receptor-driven repression of inflammatory response genes in macrophages

scientific article published on 9 February 2018

Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages.

scientific article published on 23 November 2017

Hes1 attenuates type I IFN responses via VEGF-C and WDFY1

article

IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins.

scientific article

IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1

scientific article published on 01 September 2005

Increased Th17 cells in the tumor microenvironment is mediated by IL-23 via tumor-secreted prostaglandin E2.

scientific article published on 3 May 2013

Inhibition of IFN-gamma signaling by glucocorticoids

scientific article published on 01 May 2003

Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways

scientific article published on 30 October 2008

Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

scientific article published on 30 August 2009

Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

scientific article published on 29 June 2015

MicroRNA-21: A Positive Regulator for Optimal Production of Type I and Type III Interferon by Plasmacytoid Dendritic Cells

scientific article published on 21 August 2017

MicroRNAs of the miR-17~92 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression

scientific article published on 05 November 2020

Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway

scientific article

NOTCH1 Signaling Regulates Self-Renewal and Platinum Chemoresistance of Cancer Stem-like Cells in Human Non-Small Cell Lung Cancer

scientific article published on 17 April 2017

Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression

scientific article published on 08 May 2020

Notch- and transducin-like enhancer of split (TLE)-dependent histone deacetylation explain interleukin 12 (IL-12) p70 inhibition by zymosan

scientific article published on 14 March 2011

Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

scientific article

Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1

scientific article published on 30 April 2019

RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis

scientific article published on 20 October 2014

RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes

scientific article published on 13 February 2016

RBP-J-Regulated miR-182 Promotes TNF-α-Induced Osteoclastogenesis.

scientific article published on 09 May 2016

Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

scientific article published on December 2008

Reprogramming of IL-10 activity and signaling by IFN-gamma.

scientific article published on November 2003

Role of Notch signaling in regulating innate immunity and inflammation in health and disease

scientific article

Sensitization of IFN-γ Jak-STAT signaling during macrophage activation

scientific article published on 12 August 2002

Signaling by STATs

scientific article

Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses

scientific article published on 06 August 2019

Stereotyping in East and West: live with it or deal with it?

scientific article published on 01 March 2020

Sweet Memories of 8 Empowered by Butyrate

scientific article published on 01 August 2019

Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling

scientific article published on 5 September 2013

TLE4 acts as a corepressor of Hes1 to inhibit inflammatory responses in macrophages

article

TMEM43-S358L mutation enhances NF-κB-TGFβ signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy

scientific article published on 06 July 2018

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

article

TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J.

scientific article published on 16 January 2012

The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression

scientific article

The JAK/STAT pathway in rheumatoid arthritis: Pathogenic or protective?

scientific article published on 01 August 2003

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

The transcriptional repressor Hes1 attenuates inflammation by regulating transcription elongation

scientific article published on 20 June 2016

Three paralogous clusters of the miR-17~92 family of microRNAs restrain IL-12-mediated immune defense

scientific article published on 03 February 2020

Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages

scientific article published on 22 May 2011

Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity

scientific article published on 4 September 2017

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