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List of works by Justin R. Cross

AT-35INTERMITTENT HIGH DOSE (PULSATILE) ERLOTINIB FOR EGFRvIII MUTANT RECURRENT MALIGNANT GLIOMAS: A PILOT CLINICAL TRIAL.

scientific article

ATP-citrate lyase links cellular metabolism to histone acetylation

scientific article (publication date: 22 May 2009)

Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

scientific article published in Nature

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease

scientific article published in 2022

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation

scientific article published on 04 April 2016

Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion

scientific article

Author Correction: Microbiota modulate sympathetic neurons via a gut-brain circuit

scientific article published on 20 August 2020

Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells

scientific article published on 15 April 2020

Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition

scientific article published on September 2013

Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer

scientific article published on 18 May 2016

Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia

scientific article published on 07 June 2018

Commensal bacteria make GPCR ligands that mimic human signalling molecules

scientific article published on 30 August 2017

Comparison of Topical and Intravenous Tranexamic Acid for Total Knee Replacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels

scientific article published on 20 September 2019

Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis

scientific article published on 15 December 2021

Corrigendum: Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer.

scientific article published on 29 March 2017

Corrigendum: Commensal bacteria make GPCR ligands that mimic human signalling molecules

scientific article published in Nature

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

scientific article

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

scientific article

Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness

scientific article published on 26 January 2015

Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo

scientific article published on February 2015

Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy

scientific article published in 2022

Hypoxia Induces Production of L-2-Hydroxyglutarate.

scientific article published on 23 July 2015

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

scientific article published on 21 November 2011

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

scientific article published on 13 May 2013

Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production ⬇️

scientific article published on September 26, 2011

Impact of gut colonization with butyrate producing microbiota on respiratory viral infection following allo-HCT.

scientific article published on 19 April 2018

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen

scientific article published on 13 July 2020

Induction of sarcomas by mutant IDH2

scientific article published on September 2013

Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification

scientific article published on 18 December 2018

Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma

scientific article

Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis

scientific article

Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

scientific article published on 29 June 2015

Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease

scientific article published on 11 May 2015

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation.

scientific article published in February 2018

Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation

scientific article published on 26 March 2015

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

scientific article

In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors

scientific article published on 16 October 2017

L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH

scientific article published on 6 March 2017

Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs

scientific article published on 30 May 2019

MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα

scientific article published on 22 May 2017

Mapping Interactions of Microbial Metabolites with Human G-Protein-Coupled Receptors

scientific article published on 01 August 2019

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

scientific article (publication date: 19 December 2013)

Microbe-derived short chain fatty acids butyrate and propionate are associated with protection from chronic GVHD

scientific article published on 19 May 2020

Microbiota modulate sympathetic neurons via a gut-brain circuit

scientific article published on 08 July 2020

Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus

scientific article published on 21 August 2019

Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor.

scientific article

Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial.

scientific article published on 6 May 2016

Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence.

scientific article published on 27 November 2017

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

scientific article published on 01 June 2019

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice

scientific article published on 19 March 2018

PTEN is a protein tyrosine phosphatase for IRS1

scientific article (publication date: June 2014)

Praf2 is a novel Bcl-xL/Bcl-2 interacting protein with the ability to modulate survival of cancer cells

scientific article

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

scientific article

Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress

scientific article published on 05 March 2020

Ras-driven cancer cells can scavenge exogenous lipids to support their proliferation.

scientific article published in June 2012

Serine catabolism regulates mitochondrial redox control during hypoxia

scientific article

Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype

scientific article published on 17 March 2020

Stable Isotope Tracers for Metabolic Pathway Analysis

scientific article published on 01 January 2019

TM-15GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO.

scientific article

The Intestinal Microbiota Correlates with Response and Toxicity after CAR T Cell Therapy in Patients with B-Cell Malignancies

scientific article published in 2021

The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping

scientific article published on 30 December 2021

The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis

scientific article published on 14 March 2004

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

scientific article

The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization.

scientific article published on 21 December 2012

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

scientific article

Translation in amino acid-poor environments is limited by tRNA<sup>Gln</sup> charging

scientific article published on 08 December 2020

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

scientific article published on 10 October 2019

Tumor Tissue-Specific Biomarkers of Colorectal Cancer by Anatomic Location and Stage

scientific article published on 19 June 2020

Vitamin B6 Addiction in Acute Myeloid Leukemia

scientific article published on 01 January 2020

c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma

scientific article published on 29 May 2019

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