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List of works by Valérie Capra

A functional G300S variant of the cysteinyl leukotriene 1 receptor is associated with atopy in a Tristan da Cunha isolate

scientific article

A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes.

scientific article

Antagonism of thromboxane receptors by diclofenac and lumiracoxib

Autocrine activity of cysteinyl leukotrienes in human vascular endothelial cells: Signaling through the CysLT₂ receptor

scientific article published on April 2015

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

scholarly article by Massimo Bertinaria et al published 26 November 2012 in ChemMedChem

CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors

scientific article

CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation.

scientific article published in December 2005

CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation

scientific article published on 22 March 2006

CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras.

scientific article published on April 2004

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies

scientific article

Cysteinyl-leukotriene receptors and cellular signals.

scientific article

Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

scientific article published on July 2007

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

scientific article

Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk

scientific article published in February 2010

Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke

scientific article published on 20 March 2012

Facilitation of acetylcholine signaling by the dithiocarbamate fungicide propineb.

scientific article published in January 2002

Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.

scientific article

Impact of vascular thromboxane prostanoid receptor activation on hemostasis, thrombosis, oxidative stress, and inflammation.

scientific article

Impaired thromboxane receptor dimerization reduces signaling efficiency: A potential mechanism for reduced platelet function in vivo.

scientific article

In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition.

scientific article

Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells ⬇️

scientific article published on July 1, 2003

Leukotriene modifiers in the treatment of cardiovascular diseases.

scientific article published on 15 September 2008

Leukotrienes and Atherosclerosis

scientific article published on 01 July 2010

Leukotrienes as mediators of asthma.

scientific article

Light on the structure of thromboxane A₂receptor heterodimers.

scientific article

Molecular and functional aspects of human cysteinyl leukotriene receptors

scientific article

Mutational analysis of the highly conserved ERY motif of the thromboxane A2 receptor: alternative role in G protein-coupled receptor signaling.

scientific article published on 30 June 2004

Pharmacogenetics of the G protein-coupled receptors

scientific article

Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vasc

scientific article published on 6 January 2006

Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro

scientific article

Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma.

scientific article

Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents.

scientific article published on 24 June 2013

Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor

scientific article published on 13 July 2011

The DRY motif and the four corners of the cubic ternary complex model.

scientific article published on 24 March 2017

The DRY motif at work: the P2Y12receptor case

scientific article published on 01 May 2014

The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

scientific article published on 27 December 2006

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

scientific article

Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation.

scientific article published in August 2003

Thromboxane prostanoid receptor signals through Gi protein to rapidly activate extracellular signal-regulated kinase in human airways

scientific article published on 30 December 2004

Transcellular biosynthesis of eicosanoid lipid mediators

scientific article

Working hypothesis on the classification of Cys-leukotriene receptors in airways.

scientific article published in May 1997

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