List of works - Lucielli Savegnago

1,1,2-Tris-organoselenide alkene derivatives, but not 1,2-bis-organoselenide alkene derivatives, inhibited δ-aminolevulinate dehydratase activity from human erythrocytic cells in vitro

scientific article published on 29 September 2006

4-Phenylselenyl-7-chloroquinoline, a new quinoline derivative containing selenium, has potential antinociceptive and anti-inflammatory actions

scientific article

7-Chloroquinoline-1,2,3-triazoyl carboxamides induce cell cycle arrest and apoptosis in human bladder carcinoma cells

scientific article published on 06 November 2019

A novel pyrazole-containing selenium compound modulates the oxidative and nitrergic pathways to reverse the depression-pain syndrome in mice

scientific article published on 14 May 2020

Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures.

scientific article published in April 2009

Antidepressant-like activity of dehydrozingerone: involvement of the serotonergic and noradrenergic systems

scientific article

Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice.

scientific article

Antinociceptive and anti-allodynic effects of 3-alkynyl selenophene on different models of nociception in mice.

scientific article

Antinociceptive and anti-hyperalgesic effects of bis(4-methylbenzoyl) diselenide in mice: evidence for the mechanism of action.

scientific article published on 9 December 2014

Antinociceptive and anti-hypernociceptive effects of Se-phenyl thiazolidine-4-carboselenoate in mice

scientific article published on 7 July 2011

Antinociceptive and anti-inflammatory effects of 1,2-bis-(4 methoxyphenylselanyl) styrene in mice: involvement of the serotonergic system

scientific article published on 27 March 2018

Antinociceptive properties of diphenyl diselenide: Evidences for the mechanism of action

scientific article published on 17 October 2006

Antioxidant compound (E)-2-benzylidene-4-phenyl-1,3-diselenole protects rats against thioacetamide-induced acute hepatotoxicity

scientific article published on 13 July 2017

Antioxidant properties of (R)-Se-aryl thiazolidine-4-carboselenoate.

scientific article

Antiparasitic activity of 1,3-dioxolanes containing tellurium in Trichomonas vaginalis

scientific article published on 22 February 2017

Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses

scientific article published on 11 February 2020

Antitumor activity of Brazilian red propolis fractions against Hep-2 cancer cell line

scientific article

Apoptosis induction by 7-chloroquinoline-1,2,3-triazoyl carboxamides in triple negative breast cancer cells.

scientific article published on 5 May 2017

Bis selenide alkene derivatives: A class of potential antioxidant and antinociceptive agents

scientific article published on 01 February 2006

Brazilian red propolis induces apoptosis-like cell death and decreases migration potential in bladder cancer cells

scientific article published on 3 November 2014

Cadmium inhibits the ovary δ-aminolevulinate dehydratase activity in vitro and ex vivo: protective role of seleno-furanoside.

scientific article published on 4 July 2012

Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.

scientific article published on 6 March 2008

Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa.

scientific article published in July 2005

Chemical composition, immunostimulatory, cytotoxic and antiparasitic activities of the essential oil from Brazilian red propolis

scientific article published in February 2018

Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice

scientific article published in November 2017

Contribution of dopaminergic and noradrenergic systems in the antinociceptive effect of α-(phenylalanyl) acetophenone.

scientific article published on 27 March 2017

Correction: Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice

scientific article published on 14 December 2017

Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system

scientific article published on 04 May 2019

Depressive-like behavior induced by tumor necrosis factor-α is attenuated by m-trifluoromethyl-diphenyl diselenide in mice

scientific article published on 5 May 2015

Dihydropyrimidin-(2H)-ones obtained by ultrasound irradiation: a new class of potential antioxidant agents.

scientific article published on 3 March 2006

Diphenyl diselenide attenuates acute thermal hyperalgesia and persistent inflammatory and neuropathic pain behavior in mice

scientific article published on 22 August 2007

Diphenyl diselenide exerts antidepressant-like and anxiolytic-like effects in mice: involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway in its antidepressant-like action.

scientific article published on 29 September 2007

Effect of QTC-4-MeOBnE Treatment on Memory, Neurodegeneration, and Neurogenesis in a Streptozotocin-Induced Mouse Model of Alzheimer's Disease

scientific article published on 14 December 2020

Effect of oral administration of diphenyl diselenide on antioxidant status, and activity of delta aminolevulinic acid dehydratase and isoforms of lactate dehydrogenase, in streptozotocin-induced diabetic rats.

scientific article published on 31 July 2008

Effects of Se-phenyl thiazolidine-4-carboselenoate on mechanical and thermal hyperalgesia in brachial plexus avulsion in mice: mediation by cannabinoid CB1 and CB2 receptors

scientific article published on 8 August 2012

Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice

scientific article published on 12 March 2019

Essential oil of Psidium cattleianum leaves: antioxidant and antifungal activity

scientific article

Essential oil of the leaves of Eugenia uniflora L.: antioxidant and antimicrobial properties

scientific article published on 11 May 2012

Evaluation of antioxidant activity and potential toxicity of 1-buthyltelurenyl-2-methylthioheptene

article

Evaluation of the effect of synthetic compounds derived from azidothymidine on MDA-MB-231 type breast cancer cells

scientific article published on 24 June 2020

Evaluation of the toxicity of α-(phenylselanyl) acetophenone in mice.

scientific article

Evidence for the involvement of glutamatergic and GABAergic systems and protein kinase A pathway in the antinociceptive effect caused by p-methoxy-diphenyl diselenide in mice.

scientific article published on 23 October 2007

Further analysis of the antimicrobial activity of α-phenylseleno citronellal and α-phenylseleno citronellol

Further analysis of the antinociceptive action caused by p-methoxyl-diphenyl diselenide in mice.

scientific article

Glycerol as a recyclable solvent for copper-catalyzed cross-coupling reactions of diaryl diselenides with aryl boronic acids

article published in 2012

Hepatoprotective effect of 3-alkynyl selenophene on acute liver injury induced by D-galactosamine and lipopolysaccharide

scientific journal article

Hepatoprotective effect ofbis(4-methylbenzoyl) diselenide against CCl4-induced oxidative damage in mice

scientific article published on 07 September 2012

High sucrose consumption potentiates the sub-acute cadmium effect on Na+/K+ -ATPase but not on delta-aminolevulinate dehydratase in mice.

scientific article published in November 2004

In vitro antioxidant activity and in vivo antidepressant-like effect of α-(phenylselanyl) acetophenone in mice

scientific article published on 27 March 2012

Introduction of trifluoromethyl group into diphenyl diselenide molecule alters its toxicity and protective effect against damage induced by 2-nitropropane in rats

scientific article published on 24 September 2008

Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tramadol in the rat forced swimming test

scientific article

Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test

scientific article published on 24 October 2015

Involvement of serotoninergic and adrenergic systems on the antidepressant-like effect of E. uniflora L. leaves essential oil and further analysis of its antioxidant activity.

scientific article published on 10 April 2013

Involvement of the dopaminergic and serotonergic systems in the antidepressant-like effect caused by 4-phenyl-1-(phenylselanylmethyl)-1,2,3-triazole

scientific article published on 2 August 2013

Mechanisms involved in the antinociceptive and anti-inflammatory effects of bis selenide in mice

Mechanisms involved in the antinociceptive and anti-inflammatory effects of bis selenide in mice.

scientific article published in May 2009

Meloxicam-loaded nanocapsules as an alternative to improve memory decline in an Alzheimer's disease model in mice: involvement of Na(+), K(+)-ATPase

scientific article

Modulation of PKA, PKC, CAMKII, ERK 1/2 pathways is involved in the acute antidepressant-like effect of (octylseleno)-xylofuranoside (OSX) in mice

scientific article published on 19 December 2016

Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats.

scientific article published on 25 May 2007

Neuroprotective effect of physical exercise in a mouse model of Alzheimer's disease induced by β-amyloid₁₋₄₀ peptide

scientific article

Organochalcogen compounds from glycerol: synthesis of new antioxidants

scientific article published on 27 August 2014

Palladium-Catalyzed Suzuki Cross-Coupling of 2-Haloselenophenes: Synthesis of 2-Arylselenophenes, 2,5-Diarylselenophenes, and 2-Arylselenophenyl Ketones

scientific article published on 01 May 2006

Proteomic analysis identifies differentially expressed proteins after red propolis treatment in Hep-2 cells.

scientific article published on 13 November 2013

QTC-4-MeOBnE Rescues Scopolamine-Induced Memory Deficits in Mice by Targeting Oxidative Stress, Neuronal Plasticity, and Apoptosis

scientific article published on 13 April 2020

Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease

scientific article published on 13 May 2019

Repeated administration of diphenyl ditelluride induces hematological disorders in rats

scientific article published on 24 February 2007

Role of nitric oxide/cyclic GMP/K(+) channel pathways in the antinociceptive effect caused by 2,3-bis(mesitylseleno)propenol

scientific article published in December 2007

Selanylimidazopyridine Prevents Lipopolysaccharide-Induced Depressive-Like Behavior in Mice by Targeting Neurotrophins and Inflammatory/Oxidative Mediators

scientific article published on 19 July 2018

Selective blockade of mGlu5 metabotropic glutamate receptors is hepatoprotective against fulminant hepatic failure induced by lipopolysaccharide and D-galactosamine in mice

scientific article

Selenium compounds in Click Chemistry: copper catalyzed 1,3-dipolar cycloaddition of azidomethyl arylselenides and alkynes

Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

scientific article

Spinal mechanisms of antinociceptive action caused by diphenyl diselenide.

scientific article

Spinal mechanisms of antinociceptive effect caused by oral administration of bis-selenide in mice.

scientific article

Structural modifications into diphenyl diselenide molecule do not cause toxicity in mice

article

Substituted diaryl diselenides: cytotoxic and apoptotic effect in human colon adenocarcinoma cells.

scientific article

Synthesis and antioxidant properties of novel quinoline–chalcogenium compounds

Synthesis of 1-H-1,5-benzodiazepines derivatives using SiO2/ZnCl2

Synthesis, Molecular Docking, and Preliminary Evaluation of 2-(1,2,3-Triazoyl)benzaldehydes As Multifunctional Agents for the Treatment of Alzheimer's Disease

scientific article published on 12 March 2020

The antioxidant and immunomodulatory compound 3-[(4-chlorophenyl)selanyl]-1-methyl-1H-indole attenuates depression-like behavior and cognitive impairment developed in a mouse model of breast tumor

scientific article published on 16 December 2019

The selenium-containing compound 3-((4-chlorophenyl)selanyl)-1-methyl-1H-indole reverses depressive-like behavior induced by acute restraint stress in mice: modulation of oxido-nitrosative stress and inflammatory pathway

scientific article published on 04 January 2019

Toxicological evaluation of 3-(4-Chlorophenylselanyl)-1-methyl-1H-indole through the bovine oocyte in vitro maturation model

scientific article published on 17 October 2019

Toxicological investigation and antinociceptive property of potassium thiophene-3-trifluoroborate

scientific article published on 27 March 2009

Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities

scientific article published on 13 June 2017

List of works by Lucielli Savegnago

1,1,2-Tris-organoselenide alkene derivatives, but not 1,2-bis-organoselenide alkene derivatives, inhibited δ-aminolevulinate dehydratase activity from human erythrocytic cells in vitro

4-Phenylselenyl-7-chloroquinoline, a new quinoline derivative containing selenium, has potential antinociceptive and anti-inflammatory actions

7-Chloroquinoline-1,2,3-triazoyl carboxamides induce cell cycle arrest and apoptosis in human bladder carcinoma cells

A novel pyrazole-containing selenium compound modulates the oxidative and nitrergic pathways to reverse the depression-pain syndrome in mice

Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures.

Antidepressant-like activity of dehydrozingerone: involvement of the serotonergic and noradrenergic systems

Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice.

Antinociceptive and anti-allodynic effects of 3-alkynyl selenophene on different models of nociception in mice.

Antinociceptive and anti-hyperalgesic effects of bis(4-methylbenzoyl) diselenide in mice: evidence for the mechanism of action.

Antinociceptive and anti-hypernociceptive effects of Se-phenyl thiazolidine-4-carboselenoate in mice

Antinociceptive and anti-inflammatory effects of 1,2-bis-(4 methoxyphenylselanyl) styrene in mice: involvement of the serotonergic system

Antinociceptive properties of diphenyl diselenide: Evidences for the mechanism of action

Antioxidant compound (E)-2-benzylidene-4-phenyl-1,3-diselenole protects rats against thioacetamide-induced acute hepatotoxicity

Antioxidant properties of (R)-Se-aryl thiazolidine-4-carboselenoate.

Antiparasitic activity of 1,3-dioxolanes containing tellurium in Trichomonas vaginalis

Antiparasitic activity of furanyl N-acylhydrazone derivatives against Trichomonas vaginalis: in vitro and in silico analyses

Antitumor activity of Brazilian red propolis fractions against Hep-2 cancer cell line

Apoptosis induction by 7-chloroquinoline-1,2,3-triazoyl carboxamides in triple negative breast cancer cells.

Bis selenide alkene derivatives: A class of potential antioxidant and antinociceptive agents

Brazilian red propolis induces apoptosis-like cell death and decreases migration potential in bladder cancer cells

Cadmium inhibits the ovary δ-aminolevulinate dehydratase activity in vitro and ex vivo: protective role of seleno-furanoside.

Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.

Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa.

Chemical composition, immunostimulatory, cytotoxic and antiparasitic activities of the essential oil from Brazilian red propolis

Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice

Contribution of dopaminergic and noradrenergic systems in the antinociceptive effect of α-(phenylalanyl) acetophenone.

Correction: Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice

Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system

Depressive-like behavior induced by tumor necrosis factor-α is attenuated by m-trifluoromethyl-diphenyl diselenide in mice

Dihydropyrimidin-(2H)-ones obtained by ultrasound irradiation: a new class of potential antioxidant agents.

Diphenyl diselenide attenuates acute thermal hyperalgesia and persistent inflammatory and neuropathic pain behavior in mice

Diphenyl diselenide exerts antidepressant-like and anxiolytic-like effects in mice: involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway in its antidepressant-like action.

Effect of QTC-4-MeOBnE Treatment on Memory, Neurodegeneration, and Neurogenesis in a Streptozotocin-Induced Mouse Model of Alzheimer's Disease

Effect of oral administration of diphenyl diselenide on antioxidant status, and activity of delta aminolevulinic acid dehydratase and isoforms of lactate dehydrogenase, in streptozotocin-induced diabetic rats.

Effects of Se-phenyl thiazolidine-4-carboselenoate on mechanical and thermal hyperalgesia in brachial plexus avulsion in mice: mediation by cannabinoid CB1 and CB2 receptors

Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice

Essential oil of Psidium cattleianum leaves: antioxidant and antifungal activity

Essential oil of the leaves of Eugenia uniflora L.: antioxidant and antimicrobial properties

Evaluation of antioxidant activity and potential toxicity of 1-buthyltelurenyl-2-methylthioheptene

Evaluation of the effect of synthetic compounds derived from azidothymidine on MDA-MB-231 type breast cancer cells

Evaluation of the toxicity of α-(phenylselanyl) acetophenone in mice.

Evidence for the involvement of glutamatergic and GABAergic systems and protein kinase A pathway in the antinociceptive effect caused by p-methoxy-diphenyl diselenide in mice.

Further analysis of the antimicrobial activity of α-phenylseleno citronellal and α-phenylseleno citronellol

Further analysis of the antinociceptive action caused by p-methoxyl-diphenyl diselenide in mice.

Glycerol as a recyclable solvent for copper-catalyzed cross-coupling reactions of diaryl diselenides with aryl boronic acids

Hepatoprotective effect of 3-alkynyl selenophene on acute liver injury induced by D-galactosamine and lipopolysaccharide

Hepatoprotective effect ofbis(4-methylbenzoyl) diselenide against CCl4-induced oxidative damage in mice

High sucrose consumption potentiates the sub-acute cadmium effect on Na+/K+ -ATPase but not on delta-aminolevulinate dehydratase in mice.

In vitro antioxidant activity and in vivo antidepressant-like effect of α-(phenylselanyl) acetophenone in mice

Introduction of trifluoromethyl group into diphenyl diselenide molecule alters its toxicity and protective effect against damage induced by 2-nitropropane in rats

Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tramadol in the rat forced swimming test

Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test

Involvement of serotoninergic and adrenergic systems on the antidepressant-like effect of E. uniflora L. leaves essential oil and further analysis of its antioxidant activity.

Involvement of the dopaminergic and serotonergic systems in the antidepressant-like effect caused by 4-phenyl-1-(phenylselanylmethyl)-1,2,3-triazole

Mechanisms involved in the antinociceptive and anti-inflammatory effects of bis selenide in mice

Mechanisms involved in the antinociceptive and anti-inflammatory effects of bis selenide in mice.

Meloxicam-loaded nanocapsules as an alternative to improve memory decline in an Alzheimer's disease model in mice: involvement of Na(+), K(+)-ATPase

Modulation of PKA, PKC, CAMKII, ERK 1/2 pathways is involved in the acute antidepressant-like effect of (octylseleno)-xylofuranoside (OSX) in mice

Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats.

Neuroprotective effect of physical exercise in a mouse model of Alzheimer's disease induced by β-amyloid₁₋₄₀ peptide

Organochalcogen compounds from glycerol: synthesis of new antioxidants

Palladium-Catalyzed Suzuki Cross-Coupling of 2-Haloselenophenes: Synthesis of 2-Arylselenophenes, 2,5-Diarylselenophenes, and 2-Arylselenophenyl Ketones

Proteomic analysis identifies differentially expressed proteins after red propolis treatment in Hep-2 cells.

QTC-4-MeOBnE Rescues Scopolamine-Induced Memory Deficits in Mice by Targeting Oxidative Stress, Neuronal Plasticity, and Apoptosis

Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease

Repeated administration of diphenyl ditelluride induces hematological disorders in rats

Role of nitric oxide/cyclic GMP/K(+) channel pathways in the antinociceptive effect caused by 2,3-bis(mesitylseleno)propenol

Selanylimidazopyridine Prevents Lipopolysaccharide-Induced Depressive-Like Behavior in Mice by Targeting Neurotrophins and Inflammatory/Oxidative Mediators

Selective blockade of mGlu5 metabotropic glutamate receptors is hepatoprotective against fulminant hepatic failure induced by lipopolysaccharide and D-galactosamine in mice

Selenium compounds in Click Chemistry: copper catalyzed 1,3-dipolar cycloaddition of azidomethyl arylselenides and alkynes

Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

Spinal mechanisms of antinociceptive action caused by diphenyl diselenide.

Spinal mechanisms of antinociceptive effect caused by oral administration of bis-selenide in mice.

Structural modifications into diphenyl diselenide molecule do not cause toxicity in mice

Substituted diaryl diselenides: cytotoxic and apoptotic effect in human colon adenocarcinoma cells.

Synthesis and antioxidant properties of novel quinoline–chalcogenium compounds

Synthesis of 1-H-1,5-benzodiazepines derivatives using SiO2/ZnCl2

Synthesis, Molecular Docking, and Preliminary Evaluation of 2-(1,2,3-Triazoyl)benzaldehydes As Multifunctional Agents for the Treatment of Alzheimer's Disease

The antioxidant and immunomodulatory compound 3-[(4-chlorophenyl)selanyl]-1-methyl-1H-indole attenuates depression-like behavior and cognitive impairment developed in a mouse model of breast tumor