List of works - Stephen M. Kaminsky

"Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors

scientific article published on 27 March 2014

AAV-directed persistent expression of a gene encoding anti-nicotine antibody for smoking cessation

scientific article published on June 2012

AAV-mediated persistent bevacizumab therapy suppresses tumor growth of ovarian cancer.

scientific article published on 06 August 2014

AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.

scientific article

AAVrh.10-Mediated Expression of an Anti-Cocaine Antibody Mediates Persistent Passive Immunization That Suppresses Cocaine-Induced Behavior ⬇️

scientific article published on May 1, 2012

Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.

scientific article published on 10 May 2013

Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma

scientific article

Anti-hIgE gene therapy of peanut-induced anaphylaxis in a humanized murine model of peanut allergy.

scientific article published on 23 June 2016

Brain Region-Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease).

scientific article published on 28 January 2016

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

scientific article (publication date: 9 October 2009)

Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs

scientific article

Comparative efficacy and safety of multiple routes of direct CNS administration of adeno-associated virus gene transfer vector serotype rh.10 expressing the human arylsulfatase A cDNA to nonhuman primates

scientific article

Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders

scientific article

Differences in hydrogen exchange behavior between the oxidized and reduced forms of Escherichia coli thioredoxin

scientific article published on January 1992

Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity.

scientific article published on 21 December 2012

Double-blinded, placebo-controlled, randomized gene therapy using surgery for vector delivery

scientific article published on 23 April 2012

Efficacy of an adenovirus-based anti-cocaine vaccine to reduce cocaine self-administration and reacqusition using a choice procedure in rhesus macaques.

scientific article

Evaluation of a Lipopeptide Immunogen as a Therapeutic in HIV Type 1-Seropositive Individuals

article

Evaluation of compounded bevacizumab prepared for intravitreal injection

scientific article published on January 2015

Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine

scientific article

Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations.

scientific article

Gene therapy for metachromatic leukodystrophy.

scientific article

Gene therapy to stimulate angiogenesis to treat diffuse coronary artery disease

scientific article

Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma

scientific article

HIV-1 rational vaccine design: molecular details of b12-gp120 complex structure

scientific article published on 01 June 2007

In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration.

scientific article published on 23 September 2016

In vivo gene transfer strategies to achieve partial correction of von Willebrand disease.

scientific article

Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.

scientific article published on 30 April 2016

Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis.

scientific article

Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency

scientific article published on December 2013

Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects

scientific article

P12-14. Design of hydrophilic, helical peptides that mimic the 4E10 epitope of HIV-1 gp41.

scientific article published on 22 October 2009

Persistent suppression of ocular neovascularization with intravitreal administration of AAVrh.10 coding for bevacizumab

scientific article published on 27 October 2011

Phase I/II study of intrapleural administration of a serotype rh.10 replication-deficient adeno-associated virus gene transfer vector expressing the human α1-antitrypsin cDNA to individuals with α1-antitrypsin deficiency

scientific article published on September 2014

Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors

scientific article published on 06 January 2017

Reduction of thioredoxin significantly decreases its partial specific volume and adiabatic compressibility

scientific article published on January 1992

Safety of direct administration of AAV2(CU)hCLN2, a candidate treatment for the central nervous system manifestations of late infantile neuronal ceroid lipofuscinosis, to the brain of rats and nonhuman primates

scientific article published in December 2005

Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats

scientific article published in March 2013

Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing <i>CLN2</i>

scientific article published on 01 December 2020

Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function

scientific article

Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction.

scientific article

Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice.

scientific article

List of works by Stephen M. Kaminsky

"Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors

AAV-directed persistent expression of a gene encoding anti-nicotine antibody for smoking cessation

AAV-mediated persistent bevacizumab therapy suppresses tumor growth of ovarian cancer.

AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.

AAVrh.10-Mediated Expression of an Anti-Cocaine Antibody Mediates Persistent Passive Immunization That Suppresses Cocaine-Induced Behavior ⬇️

Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.

Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma

Anti-hIgE gene therapy of peanut-induced anaphylaxis in a humanized murine model of peanut allergy.

Brain Region-Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease).

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs

Comparative efficacy and safety of multiple routes of direct CNS administration of adeno-associated virus gene transfer vector serotype rh.10 expressing the human arylsulfatase A cDNA to nonhuman primates

Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders

Differences in hydrogen exchange behavior between the oxidized and reduced forms of Escherichia coli thioredoxin

Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity.

Double-blinded, placebo-controlled, randomized gene therapy using surgery for vector delivery

Efficacy of an adenovirus-based anti-cocaine vaccine to reduce cocaine self-administration and reacqusition using a choice procedure in rhesus macaques.

Evaluation of a Lipopeptide Immunogen as a Therapeutic in HIV Type 1-Seropositive Individuals

Evaluation of compounded bevacizumab prepared for intravitreal injection

Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine

Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations.

Gene therapy for metachromatic leukodystrophy.

Gene therapy to stimulate angiogenesis to treat diffuse coronary artery disease

Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma

HIV-1 rational vaccine design: molecular details of b12-gp120 complex structure

In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration.

In vivo gene transfer strategies to achieve partial correction of von Willebrand disease.

Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.

Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis.

Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency

Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects

P12-14. Design of hydrophilic, helical peptides that mimic the 4E10 epitope of HIV-1 gp41.

Persistent suppression of ocular neovascularization with intravitreal administration of AAVrh.10 coding for bevacizumab

Phase I/II study of intrapleural administration of a serotype rh.10 replication-deficient adeno-associated virus gene transfer vector expressing the human α1-antitrypsin cDNA to individuals with α1-antitrypsin deficiency

Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors

Reduction of thioredoxin significantly decreases its partial specific volume and adiabatic compressibility

Safety of direct administration of AAV2(CU)hCLN2, a candidate treatment for the central nervous system manifestations of late infantile neuronal ceroid lipofuscinosis, to the brain of rats and nonhuman primates

Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats

Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing <i>CLN2</i>

Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function

Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction.

Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice.