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List of works by Mauricio P. Cunha

Acute atorvastatin treatment exerts antidepressant-like effect in mice via the L-arginine-nitric oxide-cyclic guanosine monophosphate pathway and increases BDNF levels

scientific article

Antidepressant-like effect of creatine in mice involves dopaminergic activation.

scientific article published on 6 June 2012

Antidepressant-like effect of extract from Polygala paniculata: involvement of the monoaminergic systems.

scientific article published in December 2011

Antidepressant-like effect of pramipexole in an inflammatory model of depression.

scientific article published on 5 November 2016

Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: evidence for the involvement of the serotonergic and noradrenergic systems.

scientific article published on 29 March 2008

Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems.

scientific article published on 30 June 2010

Antidepressant-like effect of the extract of Rosmarinus officinalis in mice: involvement of the monoaminergic system.

scientific article published on 13 March 2009

Antidepressant-like effect of ursolic acid isolated from Rosmarinus officinalis L. in mice: Evidence for the involvement of the dopaminergic system

scientific article published on 25 August 2012

Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L.

scientific article published on 16 September 2012

Anxiolytic-like effects of ursolic acid in mice

scientific article published on 8 April 2015

Atorvastatin Protects from Aβ1-40-Induced Cell Damage and Depressive-Like Behavior via ProBDNF Cleavage.

scientific article published on 5 October 2016

Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice

scientific article

Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson's model

scientific article published on 24 November 2014

Creatine Prevents Corticosterone-Induced Reduction in Hippocampal Proliferation and Differentiation: Possible Implication for Its Antidepressant Effect

scientific article published on 6 October 2016

Creatine affords protection against glutamate-induced nitrosative and oxidative stress

scientific article published on 19 January 2016

Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway

scientific article

Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A₁ and A2A receptor activation

scientific article published on 22 February 2015

Effects of Agmatine on Depressive-Like Behavior Induced by Intracerebroventricular Administration of 1-Methyl-4-phenylpyridinium (MPP(+)).

scientific article published on 9 July 2015

Effects of physical exercise and social isolation on anxiety-related behaviors in two inbred rat strains.

scientific article published on 7 June 2017

Effects of traumatic brain injury of different severities on emotional, cognitive, and oxidative stress-related parameters in mice

scientific article published on October 2010

Evidence for the involvement of 5-HT1A receptor in the acute antidepressant-like effect of creatine in mice

scientific article

Evidence for the involvement of heme oxygenase-1 in the antidepressant-like effect of zinc

scientific article published on 22 January 2017

Fluoxetine reverses depressive-like behaviors and increases hippocampal acetylcholinesterase activity induced by olfactory bulbectomy

scientific article published on 31 August 2012

Guanosine prevents nitroxidative stress and recovers mitochondrial membrane potential disruption in hippocampal slices subjected to oxygen/glucose deprivation.

scientific article published on 9 September 2016

Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.

scientific article published on 26 June 2012

Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor.

scientific article published on 30 April 2016

Interaction of zinc with antidepressants in the tail suspension test

scientific article published on 11 September 2008

Involvement of PI3K/Akt Signaling Pathway and Its Downstream Intracellular Targets in the Antidepressant-Like Effect of Creatine.

scientific article published on 6 May 2015

Involvement of PKA, PKC, CAMK-II and MEK1/2 in the acute antidepressant-like effect of creatine in mice.

scientific article

MPP+-Lesioned Mice: an Experimental Model of Motor, Emotional, Memory/Learning, and Striatal Neurochemical Dysfunctions.

scientific article published on 8 October 2016

Methylglyoxal-Mediated Dopamine Depletion, Working Memory Deficit, and Depression-Like Behavior Are Prevented by a Dopamine/Noradrenaline Reuptake Inhibitor

scientific article published on 04 October 2020

Novel approaches for the management of depressive disorders

scientific article

Nrf2 participates in depressive disorders through an anti-inflammatory mechanism

scientific article

Pramipexole, a Dopamine D2/D3 Receptor-Preferring Agonist, Prevents Experimental Autoimmune Encephalomyelitis Development in Mice.

scientific article published on 22 January 2016

Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways.

scientific article published on 26 February 2013

Repeated Methylglyoxal Treatment Depletes Dopamine in the Prefrontal Cortex, and Causes Memory Impairment and Depressive-Like Behavior in Mice

scientific article published on 30 November 2019

Rosmarinus officinalis L. hydroalcoholic extract, similar to fluoxetine, reverses depressive-like behavior without altering learning deficit in olfactory bulbectomized mice.

scientific article published on 18 June 2012

Serotonergic and noradrenergic systems are implicated in the antidepressant-like effect of ursolic acid in mice

scientific article published on 02 June 2014

Subchronic administration of creatine produces antidepressant-like effect by modulating hippocampal signaling pathway mediated by FNDC5/BDNF/Akt in mice

scientific article published on 06 July 2018

The activation of α1-adrenoceptors is implicated in the antidepressant-like effect of creatine in the tail suspension test.

scientific article published on 26 January 2013

The antidepressant-like effect of inosine in the FST is associated with both adenosine A1 and A 2A receptors.

scientific article published on 25 April 2013

The antidepressant-like effect of physical activity on a voluntary running wheel.

scientific article

The modulation of NMDA receptors and L-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test.

scientific article published on 3 January 2015

The role of the NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of duloxetine in the forced swimming test

scientific article published on 23 September 2012

Ursolic acid affords antidepressant-like effects in mice through the activation of PKA, PKC, CAMK-II and MEK1/2.

scientific article published on 24 May 2017